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  6. Caffeoylmalic acid

Caffeoylmalic acid is an orally active hydroxycinnamoyl-malate ester found in stinging nettle (Urtica dioica). Caffeoylmalic acid exhibits anti-diabetic, anti-inflammation and anti-oxidant effects. Caffeoylmalic acid shows cytotoxicity to cancer cells. Caffeoylmalic acid can be used for the researches of cancer, inflammation and metabolic disease, such as colon cancer and diabetes.

For research use only. We do not sell to patients.

Caffeoylmalic acid

Caffeoylmalic acid Chemical Structure

CAS No. : 39015-77-5

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Caffeoylmalic acid Related Antibodies

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Description

Caffeoylmalic acid is an orally active hydroxycinnamoyl-malate ester found in stinging nettle (Urtica dioica). Caffeoylmalic acid exhibits anti-diabetic, anti-inflammation and anti-oxidant effects. Caffeoylmalic acid shows cytotoxicity to cancer cells. Caffeoylmalic acid can be used for the researches of cancer, inflammation and metabolic disease, such as colon cancer and diabetes[1][2][3].

In Vitro

Caffeoylmalic acid (5-80 μM) increases glucose absoption in yeast cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Caffeoylmalic acid Related Antibodies
In Vivo

Caffeoylmalic acid (0.5 mg/kg, p.o., daily for 21 days) reduces blood glucose level in alloxan-induced diabetic mice models[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Alloxan-induced diabetic mice models[1]
Dosage: 0.5 mg/kg
Administration: Orally administration, daily for 21 days
Result: Reduced blood glucose level.
Increased body weight.
Induced the production of insulin.
Decreased total cholesterol, triglycerides and LDL as well as increased HDL.
Reduced the levels of SGOT, ALP and SGPT.
Increased RBC count and decreased WBC count.
Molecular Weight

296.23

Formula

C13H12O8
CAS No.
SMILES

O=C(/C=C/C1=CC=C(C(O)=C1)O)OC(CC(O)=O)C(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Caffeoylmalic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Caffeoylmalic acid39015-77-5OthersStinging nettleUrtica dioicaCancerDiabetesInhibitorinhibitorinhibit

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