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consumption

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87

Inhibitors & Agonists

2

Screening Libraries

1

Biochemical Assay Reagents

1

Peptides

22

Natural
Products

6

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-16688A
    RU 24969 succinate
    1 Publications Verification

    		 5-HT Receptor Neurological Disease
    RU 24969 succinate is a 5-HT receptor agonist with Ki values of 0.38 and 2.5 nM for 5-HT1B and 5-HT1A, respectively. RU 24969 decreases fluid consumption and increases forward locomotion. RU 24969 succinate can be used for the research of neurological disease .
    RU 24969 succinate
  • HY-155363
    AMPK activator 13

    		AMPK Metabolic Disease
    AMPK activator 13 is a potent activator of AMPK. AMPK activator 13 inhibits mitotic clonal expansion of 3T3-L1 cells by activating AMPK pathway and enhances cell mitochondrial oxygen consumption rate. AMPK activator 13 can be used in study obesity .
    AMPK activator 13
  • HY-138879B
    CP-601932

    (1S,5R)-CP-601927

    		 nAChR Neurological Disease
    CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR (Ki=21 nM; EC50=~ 3 μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (Ki=21 nM) and an order of magnitude lower affinity for α6 and α7 nAChR subtypes. CP-601932 selectively decreases ethanol but not sucrose consumption and operant self-administration following long-term exposure. CP-601932 can penetrate the CNS .
    CP-601932
  • HY-18686
    AS1949490
    1 Publications Verification

    		 Phosphatase Akt Metabolic Disease
    AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC50 values of 0.34, 0.62, 13, >50, >50, and >50 µM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes .
    AS1949490
  • HY-146240
    ALDH1A1-IN-3

    		Aldehyde Dehydrogenase (ALDH) Metabolic Disease
    ALDH1A1-IN-3 (compound 57) is an excellent and selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor with an IC50 value of 0.379 μM. ALDH1A1-IN-3 can effectively improve glucose consumption in HepG2 cells. ALDH1A1-IN-3 can be used for researching glucose metabolism improvement .
    ALDH1A1-IN-3
  • HY-146977
    LDHA/PDKs-IN-1

    		PDK-1 Cancer
    LDHA/PDKs-IN-1 (compound 20e) is a potent and dual inhibitor of PDKs and LDHA with IC50s of 0.8 and 0.15 μM, respectively. LDHA/PDKs-IN-1 reduces A549 cell proliferation with an EC50 of 13.2 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-1 has the potential for the research of cancer diseases .
    LDHA/PDKs-IN-1
  • HY-146978
    LDHA/PDKs-IN-2

    		PDK-1 Cancer
    LDHA/PDKs-IN-2 (compound 20k) is a potent and dual inhibitor of PDKs and LDHA with IC50s of 1.6 and 0.7 μM, respectively. LDHA/PDKs-IN-2 reduces A549 cell proliferation with an EC50 of 15.7 μM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-2 has the potential for the research of cancer diseases .
    LDHA/PDKs-IN-2
  • HY-16688AR
    RU 24969 succinate (Standard)

    		5-HT Receptor Neurological Disease
    RU 24969 (succinate) (Standard) is the analytical standard of RU 24969 (succinate). This product is intended for research and analytical applications. RU 24969 succinate is a 5-HT receptor agonist with Ki values of 0.38 and 2.5 nM for 5-HT1B and 5-HT1A, respectively. RU 24969 decreases fluid consumption and increases forward locomotion. RU 24969 succinate can be used for the research of neurological disease .
    RU 24969 succinate (Standard)
  • HY-N15691
    Tadehaginoside

    		Keap1-Nrf2 NF-κB Metabolic Disease Inflammation/Immunology
    Tadehaginoside, a phenylpropanoid glycoside, is a regulator of lipogenesis and glucose consumption. Tadehaginoside has antioxygenic property. Tadehaginoside mediates liver protection against oxidative stress injury and inflammation by regulating Nrf2 and NF-κB signaling pathways in hepatocytes. Tadehaginoside can be used for the study of obesity and diabetes .
    Tadehaginoside
  • HY-114976
    S-Allylmercapturic acid

    		Drug Metabolite Metabolic Disease
    S-Allylmercapturic acid is a biomarker of food intake (BFIs) for garlic consumption .
    S-Allylmercapturic acid
  • HY-113340
    2-Furoylglycine

    		Endogenous Metabolite Others
    2-Furoylglycine, a urinary metabolite in human, is a putative biomarker for coffee consumption .
    2-Furoylglycine
  • HY-33893
    Indole-3-methanamine
    1 Publications Verification

    		 Endogenous Metabolite Metabolic Disease
    Indole-3-methanamine is a potential biomarker for the consumption of these foods such as barley, cereals, and cereal product .
    Indole-3-methanamine
  • HY-17030
    Acamprosate calcium

    Calcium N-acetylhomotaurinate

    		 GABA Receptor iGluR Neurological Disease
    Acamprosate calcium(Campral EC) is a GABA receptor agonist and modulator of glutamatergic systems; reduces alcohol consumption in animal models of alcohol addiction.
    Acamprosate calcium
  • HY-126752
    Ophthalmic acid

    		Reactive Oxygen Species (ROS) Inflammation/Immunology
    Ophthalmic acid, an analogue of GSH, is a marker of oxidative stress and hepatic GSH consumption. Ophthalmic acid is an inhibitor of Glyoxalase I reaction .
    Ophthalmic acid
  • HY-153993
    Pyrocatechol sulfate

    		Endogenous Metabolite Others
    Pyrocatechol sulfate, a phenolic metabolite present in human plasma, is associated with the consumption of specific foods such as berries and the condition of gut microbiota. It serves as a potential urinary biomarker for kidney function, dialytic clearance, whole grain consumption, and regular coffee intake. Additionally, Pyrocatechol sulfate, along with other phenolic sulfates, plays a role in modulating various biological functions, including those related to brain health and the rhythmic beating of cardiomyocytes.
    Pyrocatechol sulfate
  • HY-W007426
    N-Methylbenzylamine

    		Biochemical Assay Reagents Others Others
    N-methylbenzylamine is a member of phenylmethylamines. N-methylbenzylamine can be found in carrot, which makes N-methylbenzylamine a potential biomarker for the consumption of these food products .
    N-Methylbenzylamine
  • HY-N0018
    Daidzin
    5+ Cited Publications

    Daidzoside; NPI-031D; Daidzein 7-O-glucoside

    		 Mitochondrial Metabolism Reverse Transcriptase Aldehyde Dehydrogenase (ALDH) Cardiovascular Disease Others Cancer
    Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption .
    Daidzin
  • HY-W267444
    Pentyl 4-hydroxybenzoate

    Amylparaben

    		 Bacterial Infection
    Pentyl 4-hydroxybenzoate (Amylparaben) is a type of paraben compound commonly used as a preservative, it has antibacterial properties and is related to the inhibition of induced oxygen consumption .
    Pentyl 4-hydroxybenzoate
  • HY-19902
    GSK1521498

    		Opioid Receptor Neurological Disease
    GSK1521498 is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 has the potential for disorders of compulsive consumption of food, alcohol, and agents .
    GSK1521498
  • HY-W041019S
    5-Hydroxytryptophol-d4

    		Endogenous Metabolite Others
    5-Hydroxytryptophol-d4 is the deuterium labeled 5-Hydroxytryptophol. 5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.
    5-Hydroxytryptophol-d4
  • HY-P2740
    Alcohol dehydrogenase, Saccharomyces cerevisiae

    EC 1.1.1.1

    		 Endogenous Metabolite Metabolic Disease
    Alcohol dehydrogenase, Saccharomyces cerevisiae is a dimeric protein in the cytosol of cells. Alcohol dehydrogenase, the key enzyme for alcohol consumption in the body, is the highest expressed in the liver and participates in the detoxification mechanism of environmental alcohol .
    Alcohol dehydrogenase, Saccharomyces cerevisiae
  • HY-113340R
    2-Furoylglycine (Standard)

    		Endogenous Metabolite Others
    2-Furoylglycine (Standard) is the analytical standard of 2-Furoylglycine. This product is intended for research and analytical applications. 2-Furoylglycine, a urinary metabolite in human, is a putative biomarker for coffee consumption .
    2-Furoylglycine (Standard)
  • HY-115066
    GSK1521498 free base

    		Opioid Receptor Neurological Disease
    GSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base has the potential for disorders of compulsive consumption of food, alcohol, and agents .
    GSK1521498 free base
  • HY-158051
    CIDD-0072424

    		PKC Neurological Disease
    CIDD-0072424 selectively inhibits Protein Kinase C-epsilon (PKCε) (Ki=54 nM). CIDD-0072424 reduces ethanol consumption and preference in a dose-dependent manner .
    CIDD-0072424
  • HY-106844
    EMD 53998

    		Phosphodiesterase (PDE) Cardiovascular Disease
    EMD 53998 is a cardiotonic agent that increases myocardial contractility as an inhibitor for phosphodiesterase III (PDE III) and a calcium sensitizer. EMD 53998 increases myocardial contractility, reduces energy consumption and the risk of inducing arrhythmias .
    EMD 53998
  • HY-115066A
    GSK1521498 free base (hydrochloride)

    		Opioid Receptor Neurological Disease
    GSK1521498 free base (hydrochloride) is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base (hydrochloride) is being used for the treatment of disorders of compulsive consumption of food, alcohol, and agents .
    GSK1521498 free base (hydrochloride)
  • HY-126752R
    Ophthalmic acid (Standard)

    		Reactive Oxygen Species (ROS) Inflammation/Immunology
    Ophthalmic acid (Standard) is the analytical standard of Ophthalmic acid. This product is intended for research and analytical applications. Ophthalmic acid, an analogue of GSH, is a marker of oxidative stress and hepatic GSH consumption. Ophthalmic acid is an inhibitor of Glyoxalase I reaction .
    Ophthalmic acid (Standard)
  • HY-15475
    UK-5099
    35+ Cited Publications

    PF-1005023

    		 Mitochondrial Metabolism Cancer
    UK-5099 (PF-1005023) is a potent inhibitor of the mitochondrial pyruvate carrier (MPC). UK-5099 (PF-1005023) inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM.
    UK-5099
  • HY-N12169
    Janthitrem A

    11,12-Epoxyjanthitrem B

    		 Others Neurological Disease
    Janthitrem A (11,12-Epoxyjanthitrem B) is a natural product that can be isolated from Penicillium janthinellum. Janthitrem A induces tremors in mice and reduces weight gain and food consumption of porina (Wiseana cervinata) larvae .
    Janthitrem A
  • HY-W007426S
    N-Methylbenzylamine-d3

    		Isotope-Labeled Compounds Others
    N-Methylbenzylamine-d3 is the deuterium labeled N-Methylbenzylamine . N-methylbenzylamine is a member of phenylmethylamines. N-methylbenzylamine can be found in carrot, which makes N-methylbenzylamine a potential biomarker for the consumption of these food products .
    N-Methylbenzylamine-d3
  • HY-N0018R
    Daidzin (Standard)

    Daidzoside (Standard); NPI-031D (Standard); Daidzein 7-O-glucoside (Standard)

    		 Reference Standards Mitochondrial Metabolism Reverse Transcriptase Aldehyde Dehydrogenase (ALDH) Others
    Daidzin (Standard) is the analytical standard of Daidzin. This product is intended for research and analytical applications. Daidzin is an isoflavone with antioxidant, anticancer, and antiatherosclerotic activities. Daidzin is a potent and selective inhibitor of mitochondrial ALDH-2. Daidzin reduces ethanol consumption .
    Daidzin (Standard)
  • HY-131901
    Phenylarsine oxide

    Oxophenylarsine; PhAsO; Arsenosobenzene

    		 Phosphatase Others
    Phenylarsine oxide (PAO), an inhibitor of endocytosis, inhibits PTPε with an IC50 of 18 μM. Phenylarsine oxide (PAO) inhibits oxygen consumption and decreases cellular ATP content overlap with those used to inhibit protein internalization .
    Phenylarsine oxide
  • HY-124778
    SW106065

    		Apoptosis Cancer
    SW106065 is an apoptosis inducer in malignant peripheral nerve sheath tumors (MPNST). SW106065 inhibits ATP consumption of sMPNST and other models of MPNST with an EC50 of 1 µM. SW106065 can be used for MPNST research .
    SW106065
  • HY-N7176R
    Kaempferol 3-O-β-D-glucuronide (Standard)

    Kaempferol-3-glucuronide (Standard); Kaempferol-3-O-glucuronide (Standard)

    		 Reference Standards Interleukin Related Metabolic Disease Inflammation/Immunology Cancer
    Prosulfocarb (Standard) is the analytical standard of Prosulfocarb. This product is intended for research and analytical applications. Prosulfocarb is a herbicide with a rapidly growing use trend. Prosulfocarb is used in winter cereals to help address the problem of increasing biotic resistance of weeds to certain pesticides. Environmental and food effects of prosulfocarb have been observed, and its transfer pattern from target crops to non-target areas has been studied. The volatility effect of prosulfocarb is an important factor explaining the inefficiency of isolated area contamination and marginal protection against residue spread .
    Kaempferol 3-O-β-D-glucuronide (Standard)
  • HY-N7176
    Kaempferol 3-O-β-D-glucuronide
    3 Publications Verification

    Kaempferol-3-glucuronide; Kaempferol-3-O-glucuronide

    		 Interleukin Related Metabolic Disease Inflammation/Immunology Cancer
    Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism .
    Kaempferol 3-O-β-D-glucuronide
  • HY-122964
    URB447

    		Cannabinoid Receptor Metabolic Disease
    URB447 is a peripherally restricted CB1 cannabinoid antagonist (IC50: 313 nM and 41 nM for rat CB1 and human CB2 receptor respectively ). URB447 lowers food intake and body-weight gain in mice without entering the brain or antagonizing central CB1-dependent responses. URB447 can be used for research of obesity .
    URB447
  • HY-170404
    KF-52

    		Phosphatase Metabolic Disease
    KF-52 is a phosphofructokinase-1 (PFK1) inhibitor, with an IC50 of 2.1 μM. KF-52 significantly increases the OCR/ECAR (OCR: oxygen consumption rate; ECAR: extracellular acidification rate) ratio .
    KF-52
  • HY-N2953
    Borapetoside E

    		Fatty Acid Synthase (FASN) Metabolic Disease
    Borapetoside E can be isolated from T. crispa. Borapetoside E improves hyperglycemia, insulin resistance, hepatic steatosis, hyperlipidemia, and oxygen consumption in obese mice. Borapetoside E also inhibits SREBPs expression in the liver and adipose tissue .
    Borapetoside E
  • HY-W017092
    1,2,3-Trimethoxybenzene

    		Biochemical Assay Reagents Others
    1,2,3-Trimethoxybenzene is a member of the class of compounds known as anisoles. 1,2,3-Trimethoxybenzene can be found in tea, which makes 1,2,3-trimethoxybenzene a potential biomarker for the consumption of this food product.
    1,2,3-Trimethoxybenzene
  • HY-W012846R
    D-Threitol (Standard)

    		Reference Standards Endogenous Metabolite Others
    3,5-Dihydroxybenzoic acid (Standard) is the analytical standard of 3,5-Dihydroxybenzoic acid. This product is intended for research and analytical applications. 3,5-Dihydroxybenzoic acid a potential biomarker for the consumption of many food products, including beer, nuts, peanut, and pulses.
    D-Threitol (Standard)
  • HY-33893R
    Indole-3-methanamine (Standard)

    		Endogenous Metabolite Metabolic Disease
    Indole-3-methanamine (Standard) is the analytical standard of Indole-3-methanamine. This product is intended for research and analytical applications. Indole-3-methanamine is a potential biomarker for the consumption of these foods such as barley, cereals, and cereal product .
    Indole-3-methanamine (Standard)
  • HY-18950
    GSK2795039
    Maximum Cited Publications
    66 Publications Verification

    		 NADPH Oxidase Reactive Oxygen Species (ROS) Apoptosis Cancer
    GSK2795039 is a NADPH oxidase 2 (NOX2) inhibitor with a mean pIC50 of 6 in different cell-free assays. GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption . GSK2795039 reduces apoptosis .
    GSK2795039
  • HY-N6692S
    Diacetoxyscirpenol-13C19

    		Endogenous Metabolite Isotope-Labeled Compounds Inflammation/Immunology
    Diacetoxyscirpenol- 13C19 is 13C labeled Diacetoxyscirpenol (HY-N6692). Diacetoxyscirpenol (DAS) is a trichothecene mycotoxin, a secondary metabolite product of fungi. Diacetoxyscirpenol (DAS) consumption induces haematological disorders (neutropenia, aplastic anemia) in human and animals .
    Diacetoxyscirpenol-13C19
  • HY-100607A
    Landiolol hydrochloride

    ONO1101 hydrochloride

    		 Adrenergic Receptor Calcium Channel Potassium Channel Reactive Oxygen Species (ROS) Cardiovascular Disease Inflammation/Immunology Endocrinology
    Landiolol (ONO1101) hydrochloride is a highly selective, ultra-short-acting competitive inhibitor of β1 adrenergic receptors. Landiolol hydrochloride specifically blocks cardiac β1 receptors, reducing heart rate and myocardial oxygen consumption. Landiolol hydrochloride inhibits TNF-α-induced excessive mitochondrial oxygen consumption and reactive oxygen species production in a sepsis model, alleviating renal injury. Landiolol hydrochloride has little effect on cardiac ion channels (such as L-type calcium current and inward rectifier potassium current) and has a weak negative inotropic effect. Landiolol hydrochloride can be used for perioperative tachycardia control and protection studies of sepsis-related acute kidney injury .
    Landiolol hydrochloride
  • HY-100607
    Landiolol

    ONO1101

    		 Adrenergic Receptor Calcium Channel Potassium Channel Reactive Oxygen Species (ROS) Cardiovascular Disease Inflammation/Immunology Endocrinology
    Landiolol (ONO1101) is a highly selective, ultra-short-acting competitive inhibitor of β1 adrenergic receptors. Landiolol specifically blocks cardiac β1 receptors, reducing heart rate and myocardial oxygen consumption. Landiolol inhibits TNF-α-induced excessive mitochondrial oxygen consumption and reactive oxygen species production in a sepsis model, alleviating renal injury. Landiolol has little effect on cardiac ion channels (such as L-type calcium current and inward rectifier potassium current) and has a weak negative inotropic effect. Landiolol can be used for perioperative tachycardia control and protection studies of sepsis-related acute kidney injury .
    Landiolol
  • HY-B2011
    Flutolanil

    		Fungal Mitochondrial Metabolism Succinate Dehydrogenase Infection
    Flutolanil is a broad-spectrum fungicide. Flutolanil inhibits mycelial oxygen consumption and succinate dehydrogenase in mitochondria Complex II. Flutolanil causes endocrine disruption and reproductive disorders in zebrafish after long-term exposure. Flutolanil can be used to control the fungal pathogens induced plant disease .
    Flutolanil
  • HY-135057
    Lauroylamide propylbetaine (35% in water)

    Lauramidopropyl betaine

    		 Biochemical Assay Reagents Others
    Lauroylamide propylbetaine (35% in water) (Lauramidopropyl betaine) is an ampholytic surfactant for cosmetic and hair compositions to enhance viscosity and has good biodegradability. Lauroylamide propylbetaine (35% in water) promotes CH4 hydrate formation by reducing the induction time and increasing the CH4 consumption rate for hydrate growth .
    Lauroylamide propylbetaine (35% in water)
  • HY-N2086S
    Ethyl palmitate-d31

    Ethyl hexadecanoate-d31

    		 Isotope-Labeled Compounds Others
    Ethyl palmitate-d31 is the deuterium labeled Ethyl palmitate. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent .
    Ethyl palmitate-d31
  • HY-W701246
    Pentyl 4-hydroxybenzoate-d11

    Amylparaben-d11

    		 Isotope-Labeled Compounds Bacterial Infection
    Pentyl 4-hydroxybenzoate-d11 (Amylparaben-d11) is the deuterium labeled Pentyl 4-hydroxybenzoate (HY-W267444). Pentyl 4-hydroxybenzoate (Amylparaben) is a type of paraben compound commonly used as a preservative, it has antibacterial properties and is related to the inhibition of induced oxygen consumption .
    Pentyl 4-hydroxybenzoate-d11
  • HY-N2086R
    Ethyl palmitate (Standard)

    Ethyl hexadecanoate (Standard)

    		 Reference Standards Others Others
    Ethyl palmitate (Standard) is the analytical standard of Ethyl palmitate. This product is intended for research and analytical applications. Ethyl palmitate, a fatty acid ethyl ester (FAEE), shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is used as a hair- and skin-conditioning agent .
    Ethyl palmitate (Standard)

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