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Pathways Recommended: Metabolic Enzyme/Protease
Results for "

chymotrypsin-like protease

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

2

Fluorescent Dye

1

Peptides

4

Natural
Products

3

Recombinant Proteins

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0961
    Merbromin

    Mercury dibromofluorescein disodium salt; ZP1

    		 Flavivirus Proteasome Others
    Merbromin is a mixed inhibitor of the 3-chymotrypsin-like protease (3CLpro) of SARS-CoV-2, with an IC50 of 2.7 μM. Merbromin effectively inhibits the replication of the Zika virus (ZIKV) and shows anti-ZIKV activity by inhibiting ZIKVpro. Merbromin can also be used as a topical disinfectant for cuts and scrapes, and it serves as a biological dye .
    Merbromin
  • HY-126085
    (±)-Alliin
    2 Publications Verification

    (±)-L-Alliin

    		 SARS-CoV Infection
    (±)-Alliin is the main active component of garlic. (±)-Alliin is a putative inhibitor of the main protease of SARS-CoV-2 (Mpro) .
    (±)-Alliin
  • HY-148073
    MeO-Succ-Arg-Pro-Tyr-AMC

    		Fluorescent Dye Others
    MeO-Succ-Arg-Pro-Tyr-AMC is an analogue of 7-amido-4-methylcoumarin (HY-D0027). MeO-Succ-Arg-Pro-Tyr-AMC is a sensitive fluorescent substrate chymotrypsin-like protease. (λex=341 nm, λem=441 nm).
    MeO-Succ-Arg-Pro-Tyr-AMC
  • HY-129867
    Z-Leu-Leu-Leu-AMC

    Z-LLL-AMC

    		 Proteasome Others
    Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like protease activity of the 20S proteasome .
    Z-Leu-Leu-Leu-AMC
  • HY-100397
    Elastatinal

    		Elastase Inflammation/Immunology
    Elastatinal is a potent and competitive inhibitor of elastase, with a Ki of 0.21 μM. Elastatinal more potently inhibits pancreatic elastase versus leucocyte elastase. Elastatinal shows no activity on human leucocyte chymotrypsin-like protease .
    Elastatinal
  • HY-126988
    SP-Chymostatin B

    α-MAPI

    		 Elastase Others
    SP-Chymostatin B (α-MAPI) is a strong inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases such as cathepsins A,B,C, H, and L. SP-Chymostatin B weakly inhibits human leucocyte elastase .
    SP-Chymostatin B
  • HY-144260
    3CPLro-IN-1

    		SARS-CoV Infection
    3CPLro-IN-1 (compound A17) is a potent and orally active inhibitor of SARS-CoV-2 3CLpro with an IC50 of 5.65 μM. 3-Chymotrypsin-like cysteine protease (3CLpro) is an indispensable protein in viral replication and represents an attractive agent target for fighting COVID-19 .
    3CPLro-IN-1
  • HY-144263
    3CPLro-IN-2

    		SARS-CoV Infection
    3CPLro-IN-2 (compound C1) is a potent and orally active inhibitor of SARS-CoV-2 3CLpro with an IC50 and Ki of 1.55 and 6.09 μM, respectively. 3-Chymotrypsin-like cysteine protease (3CLpro) is an indispensable protein in viral replication and represents an attractive agent target for fighting COVID-19 .
    3CPLro-IN-2
  • HY-W614623
    (S)-ML188

    		Virus Protease SARS-CoV Infection
    (S)-ML188 is a SARS-CoV 3-chymotrypsin-like protease (3CLpro) inhibitor (IC50: 1.5 μM). (S)-ML188 has antiviral activity with an EC50 value of 12.9 μM against SARS-CoV. (S)-ML188 inhibits the activity of 3CLpro via non-covalent binding and can be used in the study of SARS-CoV .
    (S)-ML188
  • HY-N15365
    Antcin B

    		Virus Protease SARS-CoV Infection
    Antcin B is a SARS-CoV-2 3-chymotrypsin-like protease (3CL Pro) inhibitor. Antcin B binds to multiple key amino acid residues of 3CL Pro(such as Leu141, Asn142, Glu166, His163, etc.) through hydrogen bonds, salt bridges, and hydrophobic interactions, thereby inhibiting the activity of 3CL Pro, blocking the cleavage process of viral polyproteins, and suppressing the replication of the SARS-CoV-2 virus in host cells. Antcin B is promising for research of COVID-19 .
    Antcin B
  • HY-126085R
    (±)-Alliin (Standard)

    		SARS-CoV Infection
    (±)-Alliin (Standard) is the analytical standard of (±)-Alliin. This product is intended for research and analytical applications. (±)-Alliin is the main active component of garlic. (±)-Alliin is a putative inhibitor of the main protease of SARS-CoV-2 (Mpro) .
    (±)-Alliin (Standard)

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