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burns

" in MedChemExpress (MCE) Product Catalog:

30

Inhibitors & Agonists

1

Biochemical Assay Reagents

5

Peptides

1

Inhibitory Antibodies

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-102065
    SC-19220

    		Prostaglandin Receptor Others
    SC-19220 is a competitive prostaglandinn E2 receptor antagonist. SC-19220 increases the bladder capacity and reduced the voiding efficiency of micturition (elicited by slow transvesical filling) of urethane-anesthetized rats. SC-19220 can restores the balance in bone marrow granulocyte and monocyte production after burn sepsis .
    SC-19220
  • HY-101482
    Ibuprofen piconol

    U75630

    		 COX Inflammation/Immunology
    Ibuprofen piconol is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.
    Ibuprofen piconol
  • HY-101482R
    Ibuprofen piconol (Standard)

    U75630 (Standard)

    		 Reference Standards Others Inflammation/Immunology
    Ibuprofen piconol (Standard) is the analytical standard of Ibuprofen piconol. This product is intended for research and analytical applications. Ibuprofen piconol is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.
    Ibuprofen piconol (Standard)
  • HY-W014750
    3-Acetamidocoumarin
    1 Publications Verification

    		 Biochemical Assay Reagents Inflammation/Immunology Cancer
    3-Acetamidocoumarin plays an important role in biology and medicine. 3-Acetamidocoumarin has physiological effects and has been used for many diseases such as research of burns, brucellosis-rheumatic diseases and cancer .
    3-Acetamidocoumarin
  • HY-P991591
    MOR101

    		Integrin Inflammation/Immunology
    MOR101 is a humanized monoclonal antibody inhibitor targeting ICAM-1/CD54. MOR101 can be used to study acute and chronic inflammation, such as burns .
    MOR101
  • HY-133828
    Cinanserin

    		5-HT Receptor SARS-CoV Infection
    Cinanserin (SQ 10643) is a potent and selective 5-HT2 antagonist with Ki values of 41, 3500 nM for 5-HT2, 5-HT1, respectively. Cinanserin also is a SARS-CoV 3CL pro inhibitor with an KD value of 49.4, 18.2 µM for SARS-CoV 3CL pro, HCoV-229E 3CL pro, respectively. Cinanserin reduces systemic burn edema levels .
    Cinanserin
  • HY-B0226A
    (E)-Nitrofurazone

    (E)-Nitrofural

    		 Bacterial Parasite Infection
    (E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery .
    (E)-Nitrofurazone
  • HY-107940
    Sutilains

    		Proteolytic Enzyme Others
    Sutilains is a proteolytic enzyme that dissolves necrotic tissue and hyaluronidase. Sutilains can be used as a topical debriding agent in burns .
    Sutilains
  • HY-105052
    SC 34301

    Enisoprost

    		 Prostaglandin Receptor Endocrinology
    SC 34301 (Enisoprost) is a potent and orally active PGE1 analog. SC 34301 significantly reduces bacterial translocation and improves survival for burned mice .
    SC 34301
  • HY-W748297
    NK 19 diiodide

    		Fluorescent Dye Others
    NK 19 diiodide is a photosensitive cyanin dye. NK 19 diiodide is an immunomodulator capable of modifying immunological function of the impaired lymphocytes. NK 19 diiodide can be used for research of wounds and burns .
    NK 19 diiodide
  • HY-W014750R
    3-Acetamidocoumarin (Standard)

    		Biochemical Assay Reagents Inflammation/Immunology Cancer
    3-Acetamidocoumarin plays an important role in biology and medicine. 3-Acetamidocoumarin has physiological effects and has been used for many diseases such as research of burns, brucellosis-rheumatic diseases and cancer .
    3-Acetamidocoumarin (Standard)
  • HY-W019321
    3-Butenylamine hydrochloride

    		Biochemical Assay Reagents Others
    3-Butenylamine hydrochloride can be used as an intermediate in the production of polymers, adhesives, resins and other chemicals. 3-Butenylamine hydrochloride may cause skin and eye irritation or burns, severe eye damage, and breathing problems .
    3-Butenylamine hydrochloride
  • HY-B0614
    Mafenide

    		Bacterial Antibiotic Infection
    Mafenide is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis .
    Mafenide
  • HY-B0614B
    Mafenide hydrochloride

    		Bacterial Antibiotic Infection
    Mafenide hydrochloride is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis .
    Mafenide hydrochloride
  • HY-P11211A
    D2A21 TFA

    		Bacterial Infection Cancer
    D2A21 TFA is an antimicrobial peptide with significant antimicrobial activity against Pseudomonas and bactericidal effect on burn scabs. D2A21 TFA has antitumor activity and can be used in prostate cancer research .
    D2A21 TFA
  • HY-151164
    LasR-IN-2

    		Bacterial Infection
    LasR-IN-2 is a LasR inhibitor that forms H-bonding with TRY-56 residue. LasR-IN-2 can be used in the research of bacterial infection, neutropenia, severe burns and chronic lung disease in cystic fibrosis (CF) .
    LasR-IN-2
  • HY-B0614BR
    Mafenide hydrochloride (Standard)

    		Reference Standards Bacterial Antibiotic Infection
    Mafenide (hydrochloride) (Standard) is the analytical standard of Mafenide (hydrochloride). This product is intended for research and analytical applications. Mafenide hydrochloride is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis[1][2].
    Mafenide hydrochloride (Standard)
  • HY-160864
    Torbafylline

    HWA 448

    		 Phosphodiesterase (PDE) Cancer
    Torbafylline is a PDE inhibitor. Torbafylline mitigates protein breakdown in rat skeletal muscle following burns by activating the PDE4/cAMP/EPAC/PI3K/Akt signaling pathway. Torbafylline suppresses the increased ubiquitin-proteasome-dependent protein degradation observed in the skeletal muscles of rats susceptible to cancer and sepsis .
    Torbafylline
  • HY-B0614A
    Mafenide Acetate

    		Bacterial Fungal Infection
    Mafenide Acetate is a potent sulfonamide antimicrobial agent. Mafenide Acetate exhibits antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. Mafenide Acetate also exhibits antifungal activity against filamentous fungi (e.g., Lichtheimia and Aspergillus flavus). Mafenide Acetate can be used in the research of skin grafts on burn wounds, post-traumatic invasive fungal infections, and bacterially contaminated wounds .
    Mafenide Acetate
  • HY-W415753
    Alaptide

    VUFB-15754

    		 Drug Derivative Neurological Disease Inflammation/Immunology
    Alaptide, a spirocyclic synthetic dipeptide and a derivative of melanocyte-stimulating hormone release-inhibiting factor (MIF), is a transdermal permeation modifier. Alaptide loaded on nanofibrous membranes accelerates the healing of skin incisions, particularly the healing of skin burns. Alaptide is a nootropic agent, that influences the dopaminergic system and increases homovanillic acid level in the striatum of rat models. Alaptide can be used for wound healing with large damaged areas and neurological diseases research .
    Alaptide
  • HY-107063
    AHR-1911

    10-Undecen-1-yl-thiopseudourea iodide

    		 Histamine Receptor Cancer
    AHR-1911 (10-Undecen-1-yl-Thiopseudourea Iodide;Isothiuronium) is a thiourea-based anti-inflammatory and anti-tumor agent that has an improving effect on burned skin. AHR-1911 produces histamine-like effects when injected intradermally and may reduce arterial pressure in anesthetized dogs. AHR-1911 inhibits tumor growth and reduces microsomal and C-polysome protein synthesis .
    AHR-1911
  • HY-B0226S
    Nitrofurazone-13C,15N2

    Nitrofural-13C,15N2

    		 Isotope-Labeled Compounds Infection
    Nitrofurazone- 13C, 15N2 (Nitrofural- 13C, 15N2) is the 13C and 15N labled Nitrofurazone (HY-B0226) . Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants . Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna .
    Nitrofurazone-13C,15N2
  • HY-B1497
    Silver sulfadiazine

    AgSD

    		 Bacterial DNA/RNA Synthesis Antibiotic Infection
    Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication .
    Silver sulfadiazine
  • HY-B1497R
    Silver sulfadiazine (Standard)

    AgSD (Standard)

    		 Reference Standards Bacterial DNA/RNA Synthesis Antibiotic Infection
    Silver sulfadiazine (Standard) is the analytical standard of Silver sulfadiazine. This product is intended for research and analytical applications. Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication .
    Silver sulfadiazine (Standard)
  • HY-B0614AR
    Mafenide Acetate (Standard)

    		Reference Standards Bacterial Fungal Infection
    Mafenide (Acetate) (Standard) is the analytical standard of Mafenide Acetate (HY-B0614A). This product is intended for research and analytical applications. Mafenide Acetate is a potent sulfonamide antimicrobial agent. Mafenide Acetate exhibits antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa. Mafenide Acetate also exhibits antifungal activity against filamentous fungi (e.g., Lichtheimia and Aspergillus flavus). Mafenide Acetate can be used in the research of skin grafts on burn wounds, post-traumatic invasive fungal infections, and bacterially contaminated wounds .
    Mafenide Acetate (Standard)
  • HY-P11004
    A3-APO

    		Bacterial Antibiotic Infection
    A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .
    A3-APO
  • HY-100943
    Cinanserin hydrochloride
    1 Publications Verification

    SQ 10643

    		 5-HT Receptor Influenza Virus Infection Inflammation/Immunology
    Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT2 receptor antagonist with a Ki of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT2 than for the 5-HT1 receptor (Ki of 3500 nM). Cinanserin is also an inhibitor of 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro .
    Cinanserin hydrochloride
  • HY-105174A
    BPC 157 acetate

    		JAK FAK Neurological Disease Metabolic Disease
    BPC 157 acetate is the acetate salt form of BPC 157 (HY-105174). BPC 157 acetate is the 15-amino acide fragment of gastric peptide BPC. BPC 157 acetate exhibits wound healing promoting and neuroprotective activity. BPC 157 acetate maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 acetate ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems .
    BPC 157 acetate
  • HY-P1263A
    tcY-NH2 TFA
    1 Publications Verification

    (trans-Cinnamoyl)-YPGKF-NH2 TFA

    		 Protease Activated Receptor (PAR) Metabolic Disease Inflammation/Immunology
    tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide. tcY-NH2 TFA inhibits thrombin- and AY-NH2-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology .
    tcY-NH2 TFA
  • HY-P1263
    tcY-NH2
    1 Publications Verification

    (trans-Cinnamoyl)-YPGKF-NH2

    		 Protease Activated Receptor (PAR) Metabolic Disease Inflammation/Immunology
    tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) is a potent selective PAR4 antagonist peptide. tcY-NH2 inhibits thrombin- and AY-NH2-induced platelet aggregation and endostatin release, and can be used in the research of inflammation, immunology .
    tcY-NH2

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