Search Result
Results for "
antioxidant-agent
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
11
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-145104
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Drug Derivative
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Others
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Antioxidant agent-1 is a new chalcone derivative as a potential antioxidant agent.
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-
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- HY-155123
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Monoamine Oxidase
Xanthine Oxidase
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Inflammation/Immunology
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Antioxidant agent-13 (Compound 5f) is an antioxidant agent. Antioxidant agent-13 inhibits DPPH and FRAP with IC50s of 80.33 and 85.69 μM. Antioxidant agent-13 also inhibits LOX and XO enzymes with IC50s of 16.85 and 23.01 μM .
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- HY-N11655
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Others
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Others
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Antioxidant agent-10 (Compound 3) is an antioxidant agent that exhibits moderate DPPH scavenging activity with an EC50 of 33.2 μg/mL .
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-
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- HY-143243
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Apoptosis
NF-κB
Keap1-Nrf2
Reactive Oxygen Species (ROS)
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Cardiovascular Disease
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Antioxidant agent-5 (compound D-6) is a potent antioxidant agent. Antioxidant agent-5 can inhibit oxLDL (oxidized low-density lipoprotein)-induced apoptosis and the expression of ICAM-1 and VCAM-1 in VECs. Antioxidant agent-5 suppresses oxLDL-induced increase of ROS level and nuclear translocation of NF-κB. Antioxidant agent-5 protects against oxLDL-induced endothelial injury by activating Nrf2/HO-1 anti-oxidation pathway .
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-
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- HY-P4307
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SARS-CoV
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Infection
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Antioxidant agent-9 is a peptide with the sequence Asp-Trp. Antioxidant agent-9 shows antioxidant activity. Antioxidant agent-9 also is potential as SARS-CoV-2 antiviral, with an affinity strength equal to Chloroquine (HY-17589A) and Favipiravir (HY-14768) .
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-
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- HY-174271
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Apoptosis
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Cancer
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Antioxidant agent-21 (Compound 9) is a phenolic heterocyclic compound with antioxidant and anticancer activities. Antioxidant agent-21 shows significant cytotoxicity toward human gastric adenocarcinoma (AGS) and lung cancer (A549) cells. Antioxidant agent-21 induces caspase-dependent apoptosis in cancer cells .
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- HY-145888
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Amyloid-β
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Neurological Disease
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Antioxidant agent-2 (comp 3c), an BBB-penetrated antioxidant agent and a selective metal ions chelator, presents good neuroprotective effect and hepatoprotective effect for the study of Alzheimer’s disease .
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-
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- HY-N12443
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Cytochrome P450
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Inflammation/Immunology
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Antioxidant agent-18 (compound 5) is a flavonol glycoside with antioxidant activity isolated from Ginkgo biloba. Antioxidant agent-18 scavenges DPPH radicals (IC50: 15.8 μM) and reduces cytochrome c (IC50: 14.7 μM).
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- HY-170579
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Reactive Oxygen Species (ROS)
Apoptosis
NF-κB
Keap1-Nrf2
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Inflammation/Immunology
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Antioxidant agent-20 (Compound 3d) has potent anti-inflammatory and antioxidant activity. Antioxidant agent-20 reduces reactive oxygen species (ROS) and apoptosis in a dose-dependent manner. Antioxidant agent-20 exhibits photoprotective effect against UVB-irradiated human skin keratinocytes (HaCaT) (IC50=5.13 µM) via activation of Nrf2/HO-1 signaling and inhibition of NF-κB pathway .
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-
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- HY-N12271
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Others
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Others
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Antioxidant agent-14 is a kaempferol glycoside isolated from the leaves of Brassica juncea .
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-
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- HY-20808
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COX
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Cancer
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Antioxidant agent-15 (Compound 4) is a potent antioxidant inhibition activity, with the IC50 of 15.44 nM. Antioxidant agent-15 inhibits tumor cell growth in Hela, Hep G2 and Caco-2 cells, with the IC50 of 395.26, 400.4 and 24.6 nM, respectively .
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-
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- HY-W068420
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Others
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Cancer
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Antioxidant agent-4 (Compound 2) is an effective antioxidant molecule with antilipid peroxidative activity .
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-
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- HY-N10166
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Others
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Others
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Antioxidant agent-12 is an antioxidant active ingredient that can be isolated from Chuan-maidong .
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-
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- HY-152506
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Amyloid-β
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Neurological Disease
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Antioxidant agent-8 is an orally active inhibitor of Aβ1-42 deposition. Antioxidant agent-8 inhibits fibril aggregation (IC50=11.15 µM) and promotes fibril disaggregation (IC50=6.87 µM). Antioxidant agent-8 also inhibits Cu 2+-induced Aβ1-42 fibril aggregation (IC50=3.69 µM) and promotes Cu 2+-induced Aβ1-42 fibril disaggregation (IC50=3.35 µM). Antioxidant agent-8 has antioxidant activity, anti-inflammatory activity, biosafety, blood-brain barrier permeability and neuroprotective effect .
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- HY-153757
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Others
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Cancer
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Antioxidant agent-11 (compound 3d) is a compound that has weak anti-cancer and antioxidant activities .
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- HY-155373
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-
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- HY-156468
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-
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- HY-N13153
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Others
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Inflammation/Immunology
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Antioxidant agent-19 (compound 12) is an arylbutyl glycoside with antioxidant activity that can be isolated from the bark of B. platyphylla vat. Japonica .
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- HY-146172
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Reactive Oxygen Species (ROS)
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Inflammation/Immunology
Cancer
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Antioxidant agent-3 (Compound 14q), an potent antioxidant, displays potent DPPH radicals scavenging activity and ABTS + scavenging activity with IC50s of 26.58 and 30.31 μM, respectively. Antioxidant agent-3 (Compound 14q) increases reactive oxygen species (ROS), superoxide dismutase (SOD) and glutathione (GSH), and reduced lactate dehydrogenase (LDH) in H2O2-treated HepG2 cells .
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- HY-W274194
-
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Reactive Oxygen Species (ROS)
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Others
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Antioxidant agent-7 (SD-7) is a benzodiazepine derivative with antioxidant activity with an IC50 value of 470 nM to scavenge DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical .
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-
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- HY-N8167
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Kaempferol 3-O-rhamnosylgentiobioside
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COX
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Inflammation/Immunology
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Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research .
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- HY-W101673
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-
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- HY-N3379
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-
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- HY-N4047
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Others
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Cancer
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Heveaflavone is an anticancer and antioxidant agent .
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- HY-N2943
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-
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- HY-136941
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-
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- HY-W016491
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Isopropylparaben
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Bacterial
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Infection
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Isopropyl 4-hydroxybenzoate (Isopropylparaben) is an antimicrobial and antioxidant agent .
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- HY-N0111
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- HY-136972
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-
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- HY-W101673R
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-
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- HY-N11729
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Others
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Others
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Pyrogallol-phloroglucinol-6,6-bieckol is an antioxidant agent that can be isolated from Ecklonia .
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-
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- HY-N7935
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-
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- HY-130668
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-
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- HY-123501
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-
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- HY-N11895
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-
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- HY-133965
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-
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- HY-N4203
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Fungal
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Infection
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Isopropyl ferulate, isolated from Notopterygium incisum, is used in the reduction of pharmaceuticals, preparation of antifungal agents, cosmetics and as antioxidant agent and so forth .
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- HY-120570
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Keap1-Nrf2
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Neurological Disease
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WN1316 is an oral active antioxidant agent. WN1316 shows neuroprotectant activity and can be used for study of amyotrophic lateral sclerosis .
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-
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- HY-W083373
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Antibacterial agent 65
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Bacterial
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Infection
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(E)-3,4-Dimethoxychalcone is an isoform of 3,4-Dimethoxychalcone (HY-W083373A), a potential antimicrobial and antioxidant agent.
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- HY-N7904
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Others
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Others
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Laricitrin 3-O-glucoside is an antioxidant agent. Laricitrin 3-O-glucoside correlates significantly with DPPH assay and CUPRAC assay .
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-
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- HY-136941R
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MD 1024 (Standard)
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Biochemical Assay Reagents
Reference Standards
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Others
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Antioxidant 1024 (Standard) is the analytical standard of Antioxidant 1024. This product is intended for research and analytical applications. Antioxidant 1024 (MD 1024) is an antioxidant agent and metal deactivator .
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- HY-13256AR
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OSI-420 free base (Standard); CP-373420 (Standard)
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Reference Standards
Drug Metabolite
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Cancer
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Antioxidant 1024 (Standard) is the analytical standard of Antioxidant 1024. This product is intended for research and analytical applications. Antioxidant 1024 (MD 1024) is an antioxidant agent and metal deactivator .
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- HY-W004263
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Arachidyl alcohol
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Others
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Metabolic Disease
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1-Eicosanol (Arachidyl alcohol) is a natural compound with antioxidant activity found in Justicia insularis leaves. 1-Eicosanol can be used as an antioxidant agent .
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- HY-N11469
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Others
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Others
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Cyclobisdemethoxycurcumin is an antioxidant agent with IC50s of ~250 μM and 15-20 μM in DPPH radical scavenging assay and 2-DR oxidation assay, respectively .
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-
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- HY-N0111S2
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-
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- HY-N9585
-
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Others
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Cancer
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Lutonarin is a antioxidant agent that can be isolated from green barley leaves. Lutonarin inhibits malonaldehyde formation from all lipids when in combination with Saponarin (HY-N5083) .
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-
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- HY-N11835
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Asparenydiol
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Others
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Others
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Asparenyldiol (Asparenydiol) is a antioxidant agent . Asparenyldiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- HY-N0111S
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-
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- HY-W016491R
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Isopropylparaben (Standard)
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Reference Standards
Bacterial
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Infection
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Isopropyl 4-hydroxybenzoate (Standard) is the analytical standard of Isopropyl 4-hydroxybenzoate. This product is intended for research and analytical applications. Isopropyl 4-hydroxybenzoate (Isopropylparaben) is an antimicrobial and antioxidant agent .
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-
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- HY-N0111R
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- HY-N4046
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n-Hexacosyl trans-ferulate
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Others
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Others
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Hexacosyl (E)-ferulate (n-Hexacosyl trans-ferulate) is an antioxidant agent that displays significant antioxidant activity in the DPPH (HY-112053) assay with the RC50 (50% reduction concentration) of 0.0976 mg/mL .
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- HY-B0166A
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Sodium ascorbate; Sodium L-ascorbate; Vitamin C sodium salt
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Reactive Oxygen Species (ROS)
Calcium Channel
Apoptosis
Endogenous Metabolite
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Cancer
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L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor .
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- HY-N15697
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(-)-Prinsepiol
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Others
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Metabolic Disease
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Prinsepiol ((-)-Prinsepiol) is an antioxidant agent targeting free radical scavenging. Prinsepiol exerts antioxidant activity via direct free radical neutralization and modulation of oxidative stress-related pathways. Prinsepiol is promising for research of liver injury repair and oxidative stress-related diseases .
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- HY-N10407
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Others
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Metabolic Disease
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Quercetin 3-O-rutinoside-7-O-glucoside (compound 8) is an antioxidant agent that canbe found in Hemerocallis fulva. Quercetin 3-O-rutinoside-7-O-glucoside shows strong lipid peroxidation inhibitory activities .
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- HY-B0166S6
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- HY-B0166S5
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- HY-B0166S2
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- HY-B0166S4
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- HY-B0166S3
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- HY-N10183
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Reactive Oxygen Species (ROS)
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Neurological Disease
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Crocin-4, a carotenoid constituent of saffron, is a potent and brain-penetrant antioxidant agent. Crocin-4 can inhibit the aggregation and the concomitant deposition of Aβ fibrils in the brain. Crocin-4 can be used for the research of Alzheimer's Disease. Crocin-4 also exhibits antitumor and anti-inflammatory activities .
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- HY-167628
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Dipyrone hemimagnesium; Methamizole hemimagnesium
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COX
Apoptosis
Interleukin Related
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Inflammation/Immunology
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Metamizole (Dipyrone) hemimagnesium is an anti-inflammatory and antioxidant agent with the property of reducing body temperature. Metamizole hemimagnesium can decrease the levels of C-reactive protein (CRP) and interleukin 6 (IL-6). It is also an orally active cyclooxygenase (COX) inhibitor. Metamizole hemimagnesium can inhibit cell proliferation and promote apoptosis. It can be used in the research of inflammation and fever .
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- HY-W984782
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GLUT
AMPK
PPAR
Reactive Oxygen Species (ROS)
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Metabolic Disease
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Flindersine is an antidiabetic and antioxidant agent. Flindersine can result in a decline of blood glucose levels in rats. Flindersine also reduces the body weight gain, plasma insulin concentration, urea, creatinine, total cholesterol, triglycerides and free fatty acids levels in vivo. Flindersine enhances the phophotylation of GLUT4, AMPK, and PPARγ in adipose tissues and skeletal muscles .
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- HY-W728151
-
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Endogenous Metabolite
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Cancer
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3-O-Caffeoylshikimic acid (Compound 8) is a phenolic and can be isolated from Livistona chinensis. 3-O-Caffeoylshikimic acid is an antioxidant agent. 3-O-Caffeoylshikimic acid inhibits the proliferation of human cancer cells HepG2, HL-60, K562, and CNE-1 with IC50s of 5-150 μM .
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- HY-B0166AR
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Sodium ascorbate (Standard); Sodium L-ascorbate (Standard); Vitamin C sodium salt (Standard)
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Reference Standards
Calcium Channel
Reactive Oxygen Species (ROS)
Apoptosis
Endogenous Metabolite
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Cancer
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L-Ascorbic acid (sodium salt) (Standard) is the analytical standard of L-Ascorbic acid (sodium salt). This product is intended for research and analytical applications. L-Ascorbic acid sodium salt (Sodium ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid sodium salt selectively inhibits Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid sodium salt is also a collagen deposition enhancer and an elastogenesis inhibitor .
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- HY-W012788
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Maltol
2 Publications Verification
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Endogenous Metabolite
Apoptosis
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Infection
Neurological Disease
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Maltol, a type of aromatic compound, is an antioxidant agent. Maltol enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol is an inhibitor of oxidative damage in nerve cells and is effective in preventing diabetic peripheral neuropathy (DPN). Maltol is used extensively as a safe flavoring agent and food preservative. Maltol is a metal ion chelator that can be used in the field of catalysis, cosmetics, and medicine .
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- HY-W582504
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CuCl(TPP)3
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DNA Stain
Bacterial
Fungal
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Infection
Cancer
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Chlorotris(triphenylphosphine)copper (CuCl(TPP)₃) is a DNA-targeted metal complex. Chlorotris(triphenylphosphine)copper involves non-covalent interactions (such as groove binding mode) through the copper(I) center to affect DNA function, showing inhibitory activity against bacteria, fungi, and tumor cells. Chlorotris(triphenylphosphine)copper is promising for research of antibacterial, antitumor, and antioxidant agents .
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- HY-B0166
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-
- HY-120485
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IRFI-016
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p38 MAPK
ERK
PKC
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Cardiovascular Disease
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Raxofelast (IRFI-016) is an antioxidant agent in various models of ischemia-reperfusion injury. Raxofelast has antiproliferative activity in H2O2-stimulated rat aortic smooth muscle cells. Raxofelast attenuates the activation of mitogen-activating protein kinase (MAPK), ERK kinase 1, 2 (MEK1,2) and protein kinase C (PKC) without affecting Ras expression .
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- HY-W012788R
-
|
Reference Standards
Endogenous Metabolite
Apoptosis
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Infection
Neurological Disease
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Maltol (Standard) is the analytical standard of Maltol. This product is intended for research and analytical applications. Maltol, a type of aromatic compound, is an antioxidant agent. Maltol enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol is an inhibitor of oxidative damage in nerve cells and is effective in preventing diabetic peripheral neuropathy (DPN). Maltol is used extensively as a safe flavoring agent and food preservative. Maltol is a metal ion chelator that can be used in the field of catalysis, cosmetics, and medicine .
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- HY-W012788S
-
|
Isotope-Labeled Compounds
Endogenous Metabolite
Apoptosis
|
Infection
Neurological Disease
|
Maltol-d3 is a deuterium labeled Maltol (HY-W012788). Maltol, a type of aromatic compound, is an antioxidant agent. Maltol enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol is an inhibitor of oxidative damage in nerve cells and is effective in preventing diabetic peripheral neuropathy (DPN). Maltol is used extensively as a safe flavoring agent and food preservative. Maltol is a metal ion chelator that can be used in the field of catalysis, cosmetics, and medicine .
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- HY-163616
-
|
Apoptosis
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Cancer
|
Anticancer agent 221 (Compound 4h) is an orally active anticancer agent and an antioxidant agent. Anticancer agent 221 exhibits cytotoxicity to cancer cells A549 (IC50=22.09 µg/mL) and MCF-7 (IC50=6.40 µg/mL), and induces apoptosis. Anticancer agent 221 exhibits antioxidant efficacy with an IC50 of 42.46 μM in DPPH experiment. Anticancer agent 221 exhibits antitumor efficacy against breast cancer in mouse models .
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- HY-B0166S1
-
-
- HY-W104752
-
-
- HY-B0166S
-
-
- HY-B0166R
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L-Ascorbate (Standard); Vitamin C (Standard)
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Reference Standards
Reactive Oxygen Species (ROS)
Calcium Channel
Apoptosis
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
Cancer
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L-Ascorbic acid (Standard) is the analytical standard of L-Ascorbic acid. This product is intended for research and analytical applications. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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- HY-B0166GL
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L-Ascorbate (GMP Like); Vitamin C (GMP Like)
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Reactive Oxygen Species (ROS)
Apoptosis
Calcium Channel
Endogenous Metabolite
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Neurological Disease
Metabolic Disease
Cancer
|
L-Ascorbic acid (GMP Like) is the GMP Like class L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate, Vitamin C), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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- HY-W010037
-
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COX
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Inflammation/Immunology
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2-tert-Butyl-4-methoxyphenol is a major component of Butylhydroxyanisole (BHA) (HY-B1066). 2-tert-Butyl-4-methoxyphenol is an antioxidant agent, that inhibits expression of Cox2 and Tnfa genes upon stimulation with Lipopolysaccharides (HY-D1056). 2-tert-Butyl-4-methoxyphenol exhibits anti-inflammatory activity, combined with 2,6-di-tert-butyl-4-methylphenol (BHT) .
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- HY-B0166S8
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L-Ascorbate-1; Vitamin C-13C6-1
|
Isotope-Labeled Compounds
Endogenous Metabolite
Reactive Oxygen Species (ROS)
Calcium Channel
Apoptosis
|
Cancer
|
L-Ascorbic acid- 13C6-1 (L-Ascorbate-1; Vitamin C- 13C6-1) is a 13C labeled L-Ascorbic acid (HY-B0166) . L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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- HY-133794R
-
|
Reference Standards
Drug Metabolite
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Cancer
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L-Ascorbic acid (GMP Like) (Standard) is the analytical standard of L-Ascorbic acid (GMP Like). This product is intended for research and analytical applications. L-Ascorbic acid (GMP Like) is the GMP Like class L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate, Vitamin C), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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- HY-W010037R
-
|
Reference Standards
COX
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Inflammation/Immunology
|
2-(tert-Butyl)-4-methoxyphenol (Standard) is the analytical standard of 2-(tert-Butyl)-4-methoxyphenol. This product is intended for research and analytical applications. 2-tert-Butyl-4-methoxyphenol is a major component of Butylhydroxyanisole (BHA) (HY-B1066). 2-tert-Butyl-4-methoxyphenol is an antioxidant agent, that inhibits expression of Cox2 and Tnfa genes upon stimulation with Lipopolysaccharides (HY-D1056). 2-tert-Butyl-4-methoxyphenol exhibits anti-inflammatory activity, combined with 2,6-di-tert-butyl-4-methylphenol (BHT) .
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- HY-N1353
-
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p38 MAPK
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Cardiovascular Disease
Inflammation/Immunology
|
Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3 and MAPK pathways and can scavenge DPPH (IC50=28.38 mM). Rhamnocitrin selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons. Rhamnocitrin up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE), thereby blocking NFATc3 nuclear translocation and downstream inflammatory factor expression, while inducing heme oxygenase HO-1 expression and regulating the ERK/p38 MAPK pathway, inhibiting antioxidant and pro-inflammatory cytokines (such as IL-6, IL-8) and adhesion molecules (such as ICAM-1, VCAM-1). Rhamnocitrin can be used in the study of endothelial-related inflammatory diseases (such as sepsis, acute lung injury, atherosclerosis) and neuroprotection (such as oxidative damage of PC12 cells) .
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- HY-N1353R
-
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Reference Standards
Others
p38 MAPK
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Cardiovascular Disease
Inflammation/Immunology
|
Rhamnocitrin (Standard) is the analytical standard of Rhamnocitrin. This product is intended for research and analytical applications. Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3 and MAPK pathways and can scavenge DPPH (IC50=28.38 mM). Rhamnocitrin selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons. Rhamnocitrin up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE), thereby blocking NFATc3 nuclear translocation and downstream inflammatory factor expression, while inducing heme oxygenase HO-1 expression and regulating the ERK/p38 MAPK pathway, inhibiting antioxidant and pro-inflammatory cytokines (such as IL-6, IL-8) and adhesion molecules (such as ICAM-1, VCAM-1). Rhamnocitrin can be used in the study of endothelial-related inflammatory diseases (such as sepsis, acute lung injury, atherosclerosis) and neuroprotection (such as oxidative damage of PC12 cells) .
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-
Cat. No. |
Product Name |
Type |
-
- HY-B0166GL
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L-Ascorbate (GMP Like); Vitamin C (GMP Like)
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Fluorescent Dye
|
L-Ascorbic acid (GMP Like) is the GMP Like class L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate, Vitamin C), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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Cat. No. |
Product Name |
Type |
-
- HY-W016491
-
Isopropylparaben
|
Biochemical Assay Reagents
|
Isopropyl 4-hydroxybenzoate (Isopropylparaben) is an antimicrobial and antioxidant agent .
|
-
- HY-B0166GL
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L-Ascorbate (GMP Like); Vitamin C (GMP Like)
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Biochemical Assay Reagents
|
L-Ascorbic acid (GMP Like) is the GMP Like class L-Ascorbic acid (HY-B0166). L-Ascorbic acid (L-Ascorbate, Vitamin C), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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-
- HY-W016491R
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Isopropylparaben (Standard)
|
Biochemical Assay Reagents
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Isopropyl 4-hydroxybenzoate (Standard) is the analytical standard of Isopropyl 4-hydroxybenzoate. This product is intended for research and analytical applications. Isopropyl 4-hydroxybenzoate (Isopropylparaben) is an antimicrobial and antioxidant agent .
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Cat. No. |
Product Name |
Target |
Research Area |
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- HY-P4307
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SARS-CoV
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Infection
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Antioxidant agent-9 is a peptide with the sequence Asp-Trp. Antioxidant agent-9 shows antioxidant activity. Antioxidant agent-9 also is potential as SARS-CoV-2 antiviral, with an affinity strength equal to Chloroquine (HY-17589A) and Favipiravir (HY-14768) .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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- HY-N8167
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- HY-N2943
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- HY-N0111
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- HY-N11655
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- HY-N12443
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- HY-N12271
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- HY-N10166
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- HY-N13153
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- HY-N3379
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- HY-N4047
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- HY-136972
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- HY-N11729
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- HY-N7935
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- HY-N11895
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- HY-133965
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- HY-N4203
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- HY-N7904
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- HY-W004263
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- HY-N11469
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- HY-N9585
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- HY-N11835
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- HY-N0111R
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- HY-N4046
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- HY-B0166A
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- HY-N15697
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- HY-N10183
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- HY-W984782
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- HY-W728151
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- HY-B0166AR
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- HY-W012788
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- HY-B0166
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- HY-W012788R
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- HY-B0166R
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- HY-W010037
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- HY-N1353
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Cardiovascular Disease
Flavonols
Structural Classification
Flavonoids
other families
Classification of Application Fields
Source classification
Phenols
Polyphenols
Plants
Disease Research Fields
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p38 MAPK
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Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3 and MAPK pathways and can scavenge DPPH (IC50=28.38 mM). Rhamnocitrin selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons. Rhamnocitrin up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE), thereby blocking NFATc3 nuclear translocation and downstream inflammatory factor expression, while inducing heme oxygenase HO-1 expression and regulating the ERK/p38 MAPK pathway, inhibiting antioxidant and pro-inflammatory cytokines (such as IL-6, IL-8) and adhesion molecules (such as ICAM-1, VCAM-1). Rhamnocitrin can be used in the study of endothelial-related inflammatory diseases (such as sepsis, acute lung injury, atherosclerosis) and neuroprotection (such as oxidative damage of PC12 cells) .
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- HY-N1353R
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Flavonols
Structural Classification
Flavonoids
other families
Source classification
Phenols
Polyphenols
Plants
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Reference Standards
Others
p38 MAPK
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Rhamnocitrin (Standard) is the analytical standard of Rhamnocitrin. This product is intended for research and analytical applications. Rhamnocitrin is an anti-inflammatory and antioxidant agent that targets STIM-1, NFATc3 and MAPK pathways and can scavenge DPPH (IC50=28.38 mM). Rhamnocitrin selectively inhibits oxidative stress and inflammatory responses in vascular endothelial cells and neurons. Rhamnocitrin up-regulates miR-185 to inhibit STIM-1-mediated store-operated calcium entry (SOCE), thereby blocking NFATc3 nuclear translocation and downstream inflammatory factor expression, while inducing heme oxygenase HO-1 expression and regulating the ERK/p38 MAPK pathway, inhibiting antioxidant and pro-inflammatory cytokines (such as IL-6, IL-8) and adhesion molecules (such as ICAM-1, VCAM-1). Rhamnocitrin can be used in the study of endothelial-related inflammatory diseases (such as sepsis, acute lung injury, atherosclerosis) and neuroprotection (such as oxidative damage of PC12 cells) .
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Cat. No. |
Product Name |
Chemical Structure |
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- HY-N0111S2
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Coenzyme Q10-d9 is the deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
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- HY-B0166S6
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L-Ascorbic acid-d2 is the deuterium labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a colla
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- HY-B0166S2
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L-Ascorbic acid- 13C-1 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen
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- HY-B0166S3
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L-Ascorbic acid- 13C-2 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen
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- HY-W012788S
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Maltol-d3 is a deuterium labeled Maltol (HY-W012788). Maltol, a type of aromatic compound, is an antioxidant agent. Maltol enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol is an inhibitor of oxidative damage in nerve cells and is effective in preventing diabetic peripheral neuropathy (DPN). Maltol is used extensively as a safe flavoring agent and food preservative. Maltol is a metal ion chelator that can be used in the field of catalysis, cosmetics, and medicine .
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- HY-B0166S1
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L-Ascorbic acid- 13C is the 13C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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- HY-B0166S
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L-Ascorbic acid- 13C6 is the 13C-labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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- HY-N0111S
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Coenzyme Q10-d6 is deuterium labeled Coenzyme Q10. Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
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- HY-B0166S5
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L-Ascorbic acid- 13C-4 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collag
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- HY-B0166S4
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L-Ascorbic acid- 13C-3 is the 13C labeled L-Ascorbic acid. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen
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- HY-B0166S8
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L-Ascorbic acid- 13C6-1 (L-Ascorbate-1; Vitamin C- 13C6-1) is a 13C labeled L-Ascorbic acid (HY-B0166) . L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor . L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells .
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Cat. No. |
Product Name |
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Classification |
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- HY-W012788
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Maltol
2 Publications Verification
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Sweetening Agents
Flavoring Agents
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Maltol, a type of aromatic compound, is an antioxidant agent. Maltol enhances neural function by mitigating oxidative stress and cell apoptosis. Maltol is an inhibitor of oxidative damage in nerve cells and is effective in preventing diabetic peripheral neuropathy (DPN). Maltol is used extensively as a safe flavoring agent and food preservative. Maltol is a metal ion chelator that can be used in the field of catalysis, cosmetics, and medicine .
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