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Results for "

anti-inflammatory and immunomodulatory activities

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47

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2

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4

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2

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18

Natural
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2

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Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1104
    Indoprofen

    (±)-Indoprofe

    		 Akt AMPK NF-κB p38 MAPK Inflammation/Immunology
    Indoprofen ((±)-Indoprofe) activates AKT-AMPK signaling pathway, inhibits NF-κB/MAPK signaling pathway. Indoprofen exhibits anti-inflammatory and immunomodulatory activities. Indoprofen is orally active .
    Indoprofen
  • HY-B1402
    Hydrocortisone hemisuccinate
    1 Publications Verification

    Hydrocortisone 21-hemisuccinate

    		 Interleukin Related Cardiovascular Disease Metabolic Disease Inflammation/Immunology Endocrinology
    Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a glucocorticoid, is an orally active steroidal anti-inflammatory agent (SAID) with anti-inflammatory and immunomodulatory activities. Hydrocortisone hemisuccinate inhibits the bioactivity of IL-6 and IL-3 with IC50 values of 6.7 and 21.4 μM, respectively. Hydrocortisone hemisuccinate can be used in the study of ulcerative colitis (UC) and recurrent oral ulcers .
    Hydrocortisone hemisuccinate
  • HY-B1402A
    Hydrocortisone hemisuccinate hydrate
    1 Publications Verification

    Hydrocortisone 21-hemisuccinate hydrate

    		 Interleukin Related Inflammation/Immunology Endocrinology
    Hydrocortisone hemisuccinate hydrate (Hydrocortisone 21-hemisuccinate hydrate), a glucocorticoid, is an orally active steroidal anti-inflammatory agent (SAID) with anti-inflammatory and immunomodulatory activities. Hydrocortisone hemisuccinate hydrate inhibits the bioactivity of IL-6 and IL-3 with IC50 values of 6.7 and 21.4 μM, respectively. Hydrocortisone hemisuccinate hydrate can be used in the study of ulcerative colitis (UC) and recurrent oral ulcers .
    Hydrocortisone hemisuccinate hydrate
  • HY-N7696
    Physalin F

    		Apoptosis Inflammation/Immunology
    Physalin F is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC, decreasing the spontaneous proliferation and cytokine production caused by Human T-lymphotropic virus type 1 (HTLV-1) infection .
    Physalin F
  • HY-159159
    MS-II-124

    		NOD-like Receptor (NLR) Inflammation/Immunology
    MS-II-124 is an effective and selective NLRP3 inhibitor (IC50=0.12 μM) with anti-inflammatory and immunomodulatory activities, which can be used in the research of acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) .
    MS-II-124
  • HY-N9337
    Amaroswerin

    		NO Synthase Metabolic Disease Inflammation/Immunology Cancer
    Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC50 value of 5.42 μg/mL in RAW264.7 cells .
    Amaroswerin
  • HY-151232
    (E/Z)-Rilzabrutinib

    (E/Z)-PRN1008

    		 Btk Inflammation/Immunology
    Rilzabrutinib (PRN1008) is an orally active Bruton's tyrosine kinase (BTK) inhibitor with anti-inflammatory and immunomodulatory activities. Rilzabrutinib can be used in the research of various inflammatory and immune-related diseases such as acute respiratory distress syndrome and sepsis .
    (E/Z)-Rilzabrutinib
  • HY-N2965
    Bryonolic acid

    		NO Synthase Neurological Disease Inflammation/Immunology Cancer
    Bryonolic acid is an active triterpenoid compound with immunomodulatory, anti-inflammatory, antioxidant and anticancer activities .
    Bryonolic acid
  • HY-156089
    Triptoquinone H

    		Others Inflammation/Immunology Cancer
    Triptoquinone H is a class of natural product isolated from traditional Chinese medicine Tripterygium hypoglaucu. Triptoquinone H has strong cytotoxic, immunomodulatory and anti-inflammatory activities. Triptoquinone H can be used for cancer or inflammatory diseases research .
    Triptoquinone H
  • HY-B1104R
    Indoprofen (Standard)

    (±)-Indoprofe (Standard)

    		 Akt AMPK Reference Standards NF-κB p38 MAPK Inflammation/Immunology
    Indoprofen (Standard) is the analytical standard of Indoprofen. This product is intended for research and analytical applications. Indoprofen activates AKT-AMPK signaling pathway, inhibits NF-κB/MAPK signaling pathway. Indoprofen exhibits anti-inflammatory and immunomodulatory activities. Indoprofen is orally active .
    Indoprofen (Standard)
  • HY-21075
    3-Furanoic acid

    		Endogenous Metabolite Inflammation/Immunology
    3-Furanoic acid is an active unit, and its derivatives have a wide range of anti-inflammatory activities. 3-Furanoic acid-related derivatives can target inflammation-related signaling pathways and inhibit the proliferation of synovial fibroblasts to exert immunomodulatory effects .
    3-Furanoic acid
  • HY-N7088
    Raffinose
    1 Publications Verification

    Melitose

    		 NF-κB Autophagy Keap1-Nrf2 Toll-like Receptor (TLR) MyD88 Metabolic Disease Inflammation/Immunology
    Raffinose (Melitose) regulates intestinal flora, inhibits TLR4-MyD88-NF-κB signaling pathway, and activates Nrf2 signaling pathway. Raffinose exhibits anti-inflammatory, antioxidant, and immunomodulatory activities. Raffinose is orally active .
    Raffinose
  • HY-112575
    Tiazotic acid

    		NO Synthase Infection Cardiovascular Disease Inflammation/Immunology
    Tiazotic acid is a metabolic agent that has immunomodulatory, anti-inflammatory, antioxidant, anti-ischemic, cardio- and endothelioprotective, antiplatelet, hepatoprotective activities. Tiazotic acid increases the levels of eNOS. Tiazotic acid also reduces the level of D-dimer in the blood, which reduces the risks of heart attacks and strokes in post-COVID syndrome .
    Tiazotic acid
  • HY-N8492
    Monascorubrin

    		Bacterial Calcium Channel Infection Inflammation/Immunology Cancer
    Monascorubrin is a compound that can be isolated from Monascus mycelia. Monascorubrin has activities such as anti-inflammatory, anti-tumor, antibacterial, and immunomodulatory. Monascorubrin also has certain embryotoxicity, with an ED50 of 4.3 μg for chicken embryos. Monascorubrin can be used for the research of tumors and inflammatory diseases .
    Monascorubrin
  • HY-N0313
    Euphol

    		MAGL Endogenous Metabolite Inflammation/Immunology
    Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .
    Euphol
  • HY-N0410
    Daucosterol
    5 Publications Verification

    Eleutheroside A; β-Sitosterol β-D-glucoside

    		 Apoptosis Reactive Oxygen Species (ROS) Autophagy Inflammation/Immunology Cancer
    Daucosterol is an orally active natural sterol compound, which has anti-inflammatory, anticancer and immunomodulatory activities. Daucosterol inhibits cancer cell proliferation by inducing autophagy through ROS-dependent manner. Daucosterol also inhibits colon cancer growth by inducing apoptosis, inhibiting cell migration and invasion and targeting caspase signalling pathway .
    Daucosterol
  • HY-W717504
    Glucosylceramide, plant

    		Others
    Glucosylceramide, plant is a plant-derived glycolipid with anti-inflammatory and immunomodulatory activities. Glucosylceramide, plant plays an important role in promoting cell proliferation and repair. Glucosylceramide, plant is widely used in skin care products to enhance skin barrier function. Glucosylceramide, plant has also been studied for improving nervous system health, showing potential neuroprotective effects.
    Glucosylceramide, plant
  • HY-P990782
    Efzofitimod

    		Aminoacyl-tRNA Synthetase Inflammation/Immunology
    Efzofitimod is a splice variant of the aminoacyl-tRNA synthetase HARS1, which is fused with the Fc segment of a human antibody. Efzofitimod targets the neuronal phospholipid NRP2 (neuropilin-2) and has anti-inflammatory and immunomodulatory activities. Efzofitimod can downregulate the innate and adaptive immune responses in inflammatory disease states, suppressing indirect lung disease (ILD) .
    Efzofitimod
  • HY-N7088R
    Raffinose (Standard)

    Melitose (Standard)

    		 Reference Standards NF-κB Toll-like Receptor (TLR) MyD88 Keap1-Nrf2 Autophagy Metabolic Disease Inflammation/Immunology
    Raffinose (Standard) is the analytical standard of Raffinose. This product is intended for research and analytical applications. Raffinose (Melitose) regulates intestinal flora, inhibits TLR4-MyD88-NF-κB signaling pathway, and activates Nrf2 signaling pathway. Raffinose exhibits anti-inflammatory, antioxidant, and immunomodulatory activities. Raffinose is orally active .
    Raffinose (Standard)
  • HY-B0905
    Tilmicosin
    3 Publications Verification

    LY-177370; EL-870

    		 Bacterial Antibiotic Apoptosis Calcium Channel Infection Inflammation/Immunology
    Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects .
    Tilmicosin
  • HY-B0905A
    Tilmicosin phosphate
    3 Publications Verification

    LY-177370 phosphate; EL-870 phosphate

    		 Bacterial Antibiotic Apoptosis NO Synthase COX Infection Inflammation/Immunology
    Tilmicosin (LY-177370) phosphate is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin phosphate mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin phosphate is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin phosphate has immunomodulatory and anti-inflammatory effects .
    Tilmicosin phosphate
  • HY-N0591
    Dehydrocostus Lactone
    1 Publications Verification

    (-)-Dehydrocostus lactone; Epiligulyl oxide

    		 Bacterial Apoptosis p38 MAPK NF-κB MAPKAPK2 (MK2) Akt NO Synthase Interleukin Related Caspase Infection Inflammation/Immunology Cancer
    Dehydrocostus Lactone ((-)-Dehydrocostus lactone) is a natural sesquiterpene that can be isolated from Saussurea lappa. Dehydrocostus Lactone has multiple activities such as anti-inflammatory, antibacterial, anti-tumor, and immunomodulatory effects. Dehydrocostus Lactone has an MIC of 2 µg/mL against Mycobacterium tuberculosis. Dehydrocostus Lactone can also inhibit the killing activity of cytotoxic T lymphocytes and induce apoptosis in tumor cells .
    Dehydrocostus Lactone
  • HY-B1402G
    Hydrocortisone hemisuccinate

    Hydrocortisone 21-hemisuccinate

    		 Interleukin Related Metabolic Disease Inflammation/Immunology Endocrinology
    Hydrocortisone hemisuccinate GMP (Hydrocortisone 21-hemisuccinate GMP) is a GMP-grade version of Hydrocortisone hemisuccinate (HY-B1402). GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a glucocorticoid, is an orally active steroidal anti-inflammatory agent (SAID) with anti-inflammatory and immunomodulatory activities. Hydrocortisone hemisuccinate inhibits the bioactivity of IL-6 and IL-3 with IC50 values of 6.7 and 21.4 μM, respectively. Hydrocortisone hemisuccinate can be used in the study of ulcerative colitis (UC) and recurrent oral ulcers . .
    Hydrocortisone hemisuccinate
  • HY-21075R
    3-Furanoic acid (Standard)

    		Endogenous Metabolite Inflammation/Immunology
    3-Furanoic acid (Standard) is the analytical standard of 3-Furanoic acid. This product is intended for research and analytical applications. 3-Furanoic acid is an active unit, and its derivatives have a wide range of anti-inflammatory activities. 3-Furanoic acid-related derivatives can target inflammation-related signaling pathways and inhibit the proliferation of synovial fibroblasts to exert immunomodulatory effects .
    3-Furanoic acid (Standard)
  • HY-B0905S
    Tilmicosin-d3

    LY-177370-d3; EL-870-d3

    		 Isotope-Labeled Compounds Bacterial Antibiotic Apoptosis NO Synthase COX Infection Inflammation/Immunology
    Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects .
    Tilmicosin-d3
  • HY-B0905R
    Tilmicosin (Standard)

    LY-177370 (Standard); EL-870 (Standard)

    		 Reference Standards Bacterial Antibiotic Apoptosis Calcium Channel Infection Inflammation/Immunology
    Tilmicosin (Standard) is the analytical standard of Tilmicosin. This product is intended for research and analytical applications. Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin has immunomodulatory and anti-inflammatory effects .
    Tilmicosin (Standard)
  • HY-157442
    GLPG3312

    		Salt-inducible Kinase (SIK) Discoidin Domain Receptor RIP kinase LIM Kinase (LIMK) MAP3K Bcr-Abl Src TGF-β Receptor Inflammation/Immunology
    GLPG3312 (Compound 28) is an orally active SIK inhibitor with IC50 values of 2.0 nM, 0.7 nM and 0.6 nM for SIK1, SIK2 and SIK3, respectively. GLPG3312 exhibits anti-inflammatory and immunomodulatory activity in vitro on human primary myeloid cells and in vivo in mouse models. GLPG3312 has good oral bioavailability and can be used for research on inflammatory and immune diseases .
    GLPG3312
  • HY-N0313R
    Euphol (Standard)

    		MAGL Endogenous Metabolite Inflammation/Immunology
    Euphol (Standard) is the analytical standard of Euphol. This product is intended for research and analytical applications. Euphol is a tetracyclic triterpene alcohol isolated from the sap of Euphorbia tirucalli with anti-mutagenic, anti-inflammatory and immunomodulatory effects, orally active. Euphol inhibits the monoacylglycerol lipase (MGL) activity via a reversible mechanism (IC50=315 nM). MGL inhibition in the periphery modulates the endocannabinoid system to block the development of inflammatory pain .
    Euphol (Standard)
  • HY-P3161
    Lactoferrin from Bovine milk

    		HSV Infection Inflammation/Immunology Cancer
    Lactoferrin from Bovine milk is a substance released by neutrophils. Lactoferrin from Bovine milk is an orally active multifunctional iron binding glycoprotein. Lactoferrin from Bovine milk prevents cell adhesion, growth and spreading of cell colonies. Lactoferrin from Bovine milk also has antiviral activity and inhibits microbial and viral adhesion and entry into host cells. Besides, Lactoferrin from Bovine milk has anti-inflammatory, immunomodulatory, and anti-cancer activities .
    Lactoferrin from Bovine milk
  • HY-N0410R
    Daucosterol (Standard)

    Eleutheroside A (Standard); β-Sitosterol β-D-glucoside (Standard)

    		 Reference Standards Apoptosis Reactive Oxygen Species (ROS) Autophagy Inflammation/Immunology Cancer
    Daucosterol (Standard) is the analytical standard of Daucosterol. This product is intended for research and analytical applications. Daucosterol is an orally active natural sterol compound, which has anti-inflammatory, anticancer and immunomodulatory activities. Daucosterol inhibits cancer cell proliferation by inducing autophagy through ROS-dependent manner. Daucosterol also inhibits colon cancer growth by inducing apoptosis, inhibiting cell migration and invasion and targeting caspase signalling pathway .
    Daucosterol (Standard)
  • HY-34544R
    2-Hexylthiophene (Standard)

    		Reference Standards Others Others
    Daucosterol (Standard) is the analytical standard of Daucosterol. This product is intended for research and analytical applications. Daucosterol is an orally active natural sterol compound, which has anti-inflammatory, anticancer and immunomodulatory activities. Daucosterol inhibits cancer cell proliferation by inducing autophagy through ROS-dependent manner. Daucosterol also inhibits colon cancer growth by inducing apoptosis, inhibiting cell migration and invasion and targeting caspase signalling pathway .
    2-Hexylthiophene (Standard)
  • HY-P10368
    P110 heptapeptide

    		Dynamin Reactive Oxygen Species (ROS) Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology
    P110 heptapeptide is a peptide inhibitor of the Drp1-Fis1 interaction. P110 heptapeptide has anti-inflammatory, immunomodulatory, mitochondrial protective, and neuroprotective activities. Without blocking the physiological functions of Drp1, P110 heptapeptide reduces pathological functions in many models of neurodegeneration, ischemia, and sepsis. P110 heptapeptide can be used for research on neurological and inflammatory diseases .
    P110 heptapeptide
  • HY-N0591R
    Dehydrocostus Lactone (Standard)

    (-)-Dehydrocostus lactone (Standard); Epiligulyl oxide (Standard)

    		 Reference Standards Bacterial Apoptosis p38 MAPK NF-κB MAPKAPK2 (MK2) Akt NO Synthase Interleukin Related Caspase Infection Inflammation/Immunology Cancer
    Dehydrocostus Lactone (Standard) ((-)-Dehydrocostus lactone (Standard)) is the analytical standard of Dehydrocostus Lactone (HY-N0591). This product is intended for research and analytical applications. Dehydrocostus Lactone is a natural sesquiterpene that can be isolated from Saussurea lappa. Dehydrocostus Lactone has multiple activities such as anti-inflammatory, antibacterial, anti-tumor, and immunomodulatory effects. Dehydrocostus Lactone has an MIC of 2 µg/mL against Mycobacterium tuberculosis. Dehydrocostus Lactone can also inhibit the killing activity of cytotoxic T lymphocytes and induce apoptosis in tumor cells.
    Dehydrocostus Lactone (Standard)
  • HY-B0905AR
    Tilmicosin phosphate (Standard)

    LY-177370 phosphate (Standard); EL-870 phosphate (Standard)

    		 Reference Standards Bacterial Antibiotic Apoptosis NO Synthase COX Infection Inflammation/Immunology
    Tilmicosin (phosphate) (Standard) is the analytical standard of Tilmicosin (phosphate). This product is intended for research and analytical applications. Tilmicosin (LY-177370) phosphate is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. Tilmicosin phosphate mainly acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis. Tilmicosin phosphate is effective in the treatment of respiratory diseases in livestock such as cattle, sheep and pigs. In addition, Tilmicosin phosphate has immunomodulatory and anti-inflammatory effects[1][2][3][4][5][6].
    Tilmicosin phosphate (Standard)
  • HY-156649
    Vorbipiprant

    CR6086

    		 Prostaglandin Receptor Interleukin Related MMP PD-1/PD-L1 Cardiovascular Disease Inflammation/Immunology Cancer
    Vorbipiprant (CR6086) is an orally active EP4 receptor antagonist with high selectivity for the human EP4 receptor (Ki: 16.6 nM). Vorbipiprant has immunomodulatory, anti-inflammatory, antitumor, and anti-angiogenic activities. Vorbipiprant can inhibit the expression of multiple pro-inflammatory cytokines and the activation of immune cells, and convert "cold" tumors unresponsive to immune checkpoint inhibitors into "hot" tumors. Vorbipiprant is used in the research of diseases such as rheumatoid arthritis and colon cancer .
    Vorbipiprant
  • HY-P991067
    Vensobafusp alfa

    KP-104

    		 Complement System Inflammation/Immunology
    Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody directed against terminal complement protein C5 fused to the complement factor H 1-5 domain (FH1-5). Vensobafusp alfa shows anti-inflammatory and immunomodulatory activities. The isotype control for Vensobafusp alfa can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) . .
    Vensobafusp alfa
  • HY-115913
    PDE4-IN-6

    		Phosphodiesterase (PDE) Inflammation/Immunology
    PDE4-IN-6 is a potent, safe and moderately selective PDE4 inhibitor with IC50s of 0.125 and 0.43 µM for PDE4B and PDE4D, respectively. PDE4-IN-6 can downregulate the expression level of TNF-α and IL-6. PDE4-IN-6 has potent immunomodulatory activity thereby its potential against rheumatoid arthritis. Anti-inflammatory and anti-arthritic effects .
    PDE4-IN-6
  • HY-W010649
    Isoxazole

    		HSP Epigenetic Reader Domain ATP-binding cassette (ABC) transporters Bacterial Fungal Antibiotic Infection Metabolic Disease Inflammation/Immunology Cancer
    Isoxazole is a member of the five-membered heterocycle drug scaffold. Isoxazole has been used as a BET bromodomain inhibitor and can improve β-cell function in a diabetic mouse model. Isoxazole and its derivatives exhibit broad biological activities (such as antimicrobial, antibacterial, antifungal, antiviral, anticancer, anti-inflammatory, immunomodulatory, analgesic, anti-tuberculosis, and anti-diabetic effects). For example, the bicyclic Isoxazole can act as an HSP90 inhibitor, and the tricyclic Isoxazole is promising as a selective multidrug resistance protein (MRP1) inhibitor​ .
    Isoxazole
  • HY-N0017
    Bergenin
    5 Publications Verification

    Cuscutin

    		 NF-κB Autophagy Apoptosis Bacterial Fungal Virus Protease Infection Inflammation/Immunology Cancer
    Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties .
    Bergenin
  • HY-P3206
    Serum thymic factor

    Thymulin; Thymic factor

    		 ERK Neurological Disease Inflammation/Immunology Endocrinology
    Serum thymic factor (Thymulin) is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases .
    Serum thymic factor
  • HY-N5060
    Estragole

    4-Allylanisole

    		 Parasite Apoptosis Reactive Oxygen Species (ROS) Keap1-Nrf2 NF-κB Infection Neurological Disease Inflammation/Immunology
    Estragole (4-Allylanisole) is a relatively nontoxic volatile terpenoid ether and major component of the essential oil from many plants. Estragole significantly triggers Apoptosis, suppresses LPS-induced intracellular ROS production. Estragole activats Nrf-2 and regulates NF-κB. Estragole has anti-toxoplasma, anti-inflammatory, anti-edema, antioxidant and immunomodulatory properties. Estragole blocks DRG neuron excitability. Estragole has improves gastric ulcer activity .
    Estragole
  • HY-P10056
    HEP-1

    Human ezrin peptide (324-337)

    		 HIV HCV HPV Influenza Virus Interleukin Related Infection Inflammation/Immunology
    HEP-1 (Human ezrin peptide (324 - 337)) is an orally active peptide with antiviral, anti-inflammatory, and immunomodulatory activities. HEP-1 is effective against infections by various viruses such as HIV, HCV, herpes viruses, HPV, and influenza viruses. As an immunomodulator, HEP-1 can enhance the adaptive immunity mediated by B cells and T cells. HEP-1 can also increase the antibody titers after hepatitis B vaccination. HEP-1 can be used in the research of viral infections and inflammation-related diseases .
    HEP-1
  • HY-19867A
    Burixafor hydrobromide
    2 Publications Verification

    TG-0054 hydrobromide

    		 CXCR VEGFR Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Burixafor (TG-0054) hydrobromide is a selective, orally active CXCR4 antagonist that effectively blocks the interaction between CXCR4 and its ligand, stromal cell-derived factor SDF-1. Burixafor hydrobromide interferes with the SDF-1/CXCR4 signaling pathway, prompting the release of bone marrow stem cells into the peripheral circulation, exerting immunomodulatory and anti-inflammatory activities. Burixafor hydrobromide can be used in the study of cancer, Intraocular neovascular diseases (such as choroidal neovascularization), myocardial infarction and other diseases, with the potential to mobilize stem cells, improve cardiac function and reduce inflammatory responses .
    Burixafor hydrobromide
  • HY-N0017R
    Bergenin (Standard)

    Cuscutin (Standard)

    		 NF-κB Reference Standards Autophagy Apoptosis Bacterial Fungal Virus Protease Infection Inflammation/Immunology Cancer
    Bergenin (Standard) is the analytical standard of Bergenin. This product is intended for research and analytical applications. Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties .
    Bergenin (Standard)
  • HY-P3206A
    Serum thymic factor acetate

    Thymulin acetate; Thymic factor acetate

    		 ERK Neurological Disease Inflammation/Immunology Endocrinology
    Serum thymic factor acetate (Thymulin acetate) is the acetate salt form of Serum thymic factor (HY-P3206). Serum thymic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor acetate stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor acetate protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases .
    Serum thymic factor acetate
  • HY-N5060S
    Estragole-d4

    4-Allylanisole-d4

    		 Parasite Isotope-Labeled Compounds Neurological Disease
    Estragole-d4 is deuterated labeled Estragole (HY-N5060). Estragole (4-Allylanisole) is a relatively nontoxic volatile terpenoid ether and major component of the essential oil from many plants. Estragole significantly triggers Apoptosis, suppresses LPS-induced intracellular ROS production. Estragole activats Nrf-2 and regulates NF-κB. Estragole has anti-toxoplasma, anti-inflammatory, anti-edema, antioxidant and immunomodulatory properties. Estragole blocks DRG neuron excitability. Estragole has improves gastric ulcer activity [10] .
    Estragole-d4
  • HY-B0766
    Bicyclol

    SY801

    		 Autophagy Apoptosis HBV HCV HSP Reactive Oxygen Species (ROS) Bcl-2 Family Glutathione S-transferase p38 MAPK NF-κB Microtubule/Tubulin ERK JNK TNF Receptor Interleukin Related CDK Cyclin G-associated Kinase (GAK) mTOR P-glycoprotein Ferroptosis Infection Inflammation/Immunology Cancer
    Bicyclol (SY801) is an orally active derivative of the traditional Chinese medicine Schisandra chinensis, which has antiviral, anti-inflammatory, immunomodulatory, antioxidant, anti-steatosis, anti-fibrotic and anti-tumor activities. Bicyclol regulates the expression of heat shock proteins and plays an anti-apoptosis role in hepatocytes. Bicyclol reduces the activation of NF-κB and the levels of inflammatory factors in hepatocytes infected with hepatitis C virus (HCV) by inhibiting the activation of the ROS-MAPK-NF-κB pathway, and prevents ferroptosis in acute liver injury. Bicyclol can change the expression of Mdr-1, GSH/GST and Bcl-2, increase the intracellular concentration of anticancer drugs, and sensitize drug-resistant cells to anticancer drugs. Bicyclol inhibits the proliferation of human malignant hepatoma cells by regulating the PI3K/AKT pathway and the Ras/Raf/MEK/ERK pathway. Bicyclol can be used in the study of chronic hepatitis, acute liver injury, nonalcoholic fatty liver disease, liver fibrosis and hepatocellular carcinoma .
    Bicyclol

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