Search Result
Results for "
amino-sugar
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
7
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W016445
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1-amino-1-deoxy-D-glucitol, 98%
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Biochemical Assay Reagents
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Others
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D-Glucamine, 98% (1-Amino-1-deoxy-D-glucitol, 98%) is an amino-sugar derivative and can be used as an excipient in pharmaceutical formulations. D-Glucamine, 98% can also be used as a substrate for sugar transporter pathway assay studies .
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- HY-N0733S3
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- HY-B0342
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Methylglucamine; Meglumin; Methylglucamin
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Biochemical Assay Reagents
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Cancer
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Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
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- HY-130480
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AIM2
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Inflammation/Immunology
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Fructose-arginine, an amino-sugar, is an AIM2 inflammasome activation inhibitor. Fructose-arginine attenuates the secretion of IL-1β, IL-18, and caspase-1, and Asc pyroptosome formation and Gsdmd cleavage resulting from AIM2 inflammasome activation .
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- HY-N15740
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Endogenous Metabolite
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Others
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Chondrosamine, 6-phosphate is an amino sugar phosphate compound that participates in sugar metabolism and amino sugar metabolic pathways .
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- HY-N0733S4
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- HY-N0733S
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- HY-113407C
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Drug Intermediate
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Metabolic Disease
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D-Fructose-6-phosphate disodium monohydrate is an intermediate of Glycolysis. D-Fructose-6-phosphate disodium monohydrate is the precursor for the synthesis of amino sugars, such as galactosamine and glucosamine .
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- HY-N0733S1
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- HY-N0733S2
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- HY-113407CR
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Reference Standards
Drug Intermediate
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Metabolic Disease
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D-Fructose-6-phosphate disodium monohydrate (Standard) is the analytical standard of D-Fructose-6-phosphate disodium monohydrate. D-Fructose-6-phosphate is an intermediate of Glycolysis. D-Fructose-6-phosphate is the precursor for the synthesis of amino sugars, such as galactosamine and glucosamine .
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- HY-B1125
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- HY-N0733
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D-(+)-Glucosamine hydrochloride; Chitosamine hydrochloride
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Endogenous Metabolite
Reactive Oxygen Species (ROS)
HIF/HIF Prolyl-Hydroxylase
Autophagy
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Inflammation/Immunology
Cancer
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Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine hydrochloride also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
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- HY-N0487
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- HY-B0342R
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Methylglucamine (Standard); Meglumin (Standard); Methylglucamin (Standard)
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Biochemical Assay Reagents
Reference Standards
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Cancer
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Meglumine (Standard) is the analytical standard of Meglumine. This product is intended for research and analytical applications. Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
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- HY-113407CS
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Isotope-Labeled Compounds
Drug Intermediate
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Metabolic Disease
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D-Fructose-6-phosphate disodium monohydrate- 13C6 is the 13C-labeled D-Fructose-6-phosphate disodium monohydrate (HY-113407C). D-Fructose-6-phosphate disodium monohydrate is an intermediate of Glycolysis. D-Fructose-6-phosphate disodium monohydrate is the precursor for the synthesis of amino sugars, such as galactosamine and glucosamine .
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- HY-N0733R
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D-(+)-Glucosamine hydrochloride (Standard); Chitosamine hydrochloride (Standard)
|
Reference Standards
Endogenous Metabolite
Reactive Oxygen Species (ROS)
HIF/HIF Prolyl-Hydroxylase
Autophagy
|
Inflammation/Immunology
Cancer
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Glucosamine (hydrochloride) (Standard) is the analytical standard of Glucosamine (hydrochloride). This product is intended for research and analytical applications. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine hydrochloride also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
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- HY-B1125S
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- HY-B0342GL
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Methylglucamine (GMP Like); Meglumin (GMP Like); Methylglucamin (GMP Like)
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Biochemical Assay Reagents
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Cancer
|
Meglumine (GMP Like) (Methylglucamine (GMP Like)) is the GMP Like class Meglumine (HY-B0342) that can be used as pharmaceutical excipients. Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
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- HY-N0487R
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|
Endogenous Metabolite
Reactive Oxygen Species (ROS)
HIF/HIF Prolyl-Hydroxylase
Autophagy
|
Inflammation/Immunology
Cancer
|
Glucosamine (sulfate) (Standard) is the analytical standard of Glucosamine (sulfate). This product is intended for research and analytical applications. Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine sulfate also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
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- HY-128852
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Galectin
Endogenous Metabolite
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Others
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N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets .
N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin .
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- HY-P2075
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Renin
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Endocrinology
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EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .
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- HY-P11004
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Bacterial
Antibiotic
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Infection
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A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .
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- HY-P2336A
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Melanocortin Receptor
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Cancer
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CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
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- HY-W142618
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Biochemical Assay Reagents
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Others
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D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.
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- HY-P10472
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GnRH Receptor
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Endocrinology
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Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
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- HY-P4757
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Parasite
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Others
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N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
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- HY-P10341
-
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GCGR
|
Metabolic Disease
|
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
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- HY-P10876
-
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Amyloid-β
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Neurological Disease
|
mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .
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- HY-D1056E
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LPS, from Pseudomonas aeruginosa (10)
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Toll-like Receptor (TLR)
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Inflammation/Immunology
|
Lipopolysaccharides from P. aeruginosa (Pseudomonas aeruginosa) 10 are lipopolysaccharide endotoxins and TLR4 activators derived from Pseudomonas aeruginosa 10, and are classified as S-type LPS. Lipopolysaccharides from P. aeruginosa 10 exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. The lipopolysaccharides of P. aeruginosa 10 have a fatty acid composition distinct from common enterobacteria, an exceptionally high degree of phosphorylation (triphosphate residues have been detected), and a unique outer region of the core oligosaccharide. Additionally, their O-specific side chains are typically rich in novel aminosugars. Lipopolysaccharides from P. aeruginosa 10 demonstrate susceptibility to viruses, with the level of susceptibility determined by the content of high molecular weight polysaccharides in their composition. The absence of high molecular weight polysaccharides increases their sensitivity to bacteriophages .
It is recommended to prepare a stock solution of ≥2 mg/mL and ensure that it is fully mixed and dissolved. Due to the adsorption characteristics of LPS, low adsorption centrifuge tubes should be used for aliquoting and storage.
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- HY-P2434
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Somatostatin Receptor
|
Neurological Disease
Metabolic Disease
Cancer
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AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
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- HY-P5362A
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Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
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Cancer
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NODAGA-LM3 TFA can be labeled by 68Ga for PET imaging. 68Ga-NODAGA-LM3 TFA is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 TFA can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
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- HY-P5362
-
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Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
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Cancer
|
NODAGA-LM3 can be labeled by 68Ga for PET imaging. 68Ga-NODAGA-LM3 is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
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- HY-105168
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Endothelin Receptor
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Cardiovascular Disease
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TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-B0342GL
-
Methylglucamine (GMP Like); Meglumin (GMP Like); Methylglucamin (GMP Like)
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Fluorescent Dye
|
Meglumine (GMP Like) (Methylglucamine (GMP Like)) is the GMP Like class Meglumine (HY-B0342) that can be used as pharmaceutical excipients. Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
|
Cat. No. |
Product Name |
Type |
-
- HY-W016445
-
1-amino-1-deoxy-D-glucitol, 98%
|
Carbohydrates
|
D-Glucamine, 98% (1-Amino-1-deoxy-D-glucitol, 98%) is an amino-sugar derivative and can be used as an excipient in pharmaceutical formulations. D-Glucamine, 98% can also be used as a substrate for sugar transporter pathway assay studies .
|
-
- HY-128852
-
|
Carbohydrates
|
N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets .
N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin .
|
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- HY-W142618
-
|
Carbohydrates
|
D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.
|
-
- HY-D1056E
-
LPS, from Pseudomonas aeruginosa (10)
|
Carbohydrates
|
Lipopolysaccharides from P. aeruginosa (Pseudomonas aeruginosa) 10 are lipopolysaccharide endotoxins and TLR4 activators derived from Pseudomonas aeruginosa 10, and are classified as S-type LPS. Lipopolysaccharides from P. aeruginosa 10 exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. The lipopolysaccharides of P. aeruginosa 10 have a fatty acid composition distinct from common enterobacteria, an exceptionally high degree of phosphorylation (triphosphate residues have been detected), and a unique outer region of the core oligosaccharide. Additionally, their O-specific side chains are typically rich in novel aminosugars. Lipopolysaccharides from P. aeruginosa 10 demonstrate susceptibility to viruses, with the level of susceptibility determined by the content of high molecular weight polysaccharides in their composition. The absence of high molecular weight polysaccharides increases their sensitivity to bacteriophages .
It is recommended to prepare a stock solution of ≥2 mg/mL and ensure that it is fully mixed and dissolved. Due to the adsorption characteristics of LPS, low adsorption centrifuge tubes should be used for aliquoting and storage.
|
-
- HY-B0342GL
-
Methylglucamine (GMP Like); Meglumin (GMP Like); Methylglucamin (GMP Like)
|
Biochemical Assay Reagents
|
Meglumine (GMP Like) (Methylglucamine (GMP Like)) is the GMP Like class Meglumine (HY-B0342) that can be used as pharmaceutical excipients. Meglumine (Methylglucamine) is an orally active amino sugar derived from sorbitol. Meglumine has anti-inflammatory and antitumor activity. Meglumine is often used as an excipient in active molecules and with iodinated compounds in contrast agents such as meglumine and meglumine iodide .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P2336A
-
|
Melanocortin Receptor
|
Cancer
|
CCZ01048 TFA, a α-MSH analogue, exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0.31 nM. CCZ01048 TFA shows rapid internalization into B16F10 melanoma cells and high in vivo stability. CCZ01048 TFA is a promising candidate for PET imaging of malignant melanoma .
|
-
- HY-P10341
-
|
GCGR
|
Metabolic Disease
|
ZP3022 is a dual agonist of glucagon-like peptide-1 (GLP-1) and gastrin that has the ability to sustainably improve glycemic control. Additionally, ZP3022 can effectively increase β-cell mass, promote β-cell proliferation, and enhance the function of pancreatic islets. ZP3022 can be used in anti-diabetic research .
|
-
- HY-P5362
-
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Cancer
|
NODAGA-LM3 can be labeled by 68Ga for PET imaging. 68Ga-NODAGA-LM3 is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
|
-
- HY-P2075
-
|
Renin
|
Endocrinology
|
EMD 55068 is a renin antagonist. EMD 55068 inhibits the uptake of taurocholate .
|
-
- HY-P11004
-
|
Bacterial
Antibiotic
|
Infection
|
A3-APO is an antimicrobial peptide. A3-APO has a significant antimicrobial activity by a dual mode of action with both membrane disintegration and intracellular target inhibition. A3-APO can deactivate bacterial toxins and increase the expression of anti-inflammatory cytokines (such as IL-4 and IL-10), without antimicrobial resistance. A3-APO accelerates burn wounds healing in mice infection model of Acinetobacter baumannii and Staphylococcus aureus .
|
-
- HY-P10472
-
|
GnRH Receptor
|
Endocrinology
|
Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
|
-
- HY-P4757
-
|
Parasite
|
Others
|
N1-Glutathionyl-spermidine disulfide is a substrate of trypanothione reductase .
|
-
- HY-P10876
-
|
Amyloid-β
|
Neurological Disease
|
mcK6A1 is an inhibitor for the aggregation of amyloid-β (Aβ), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases .
|
-
- HY-P2434
-
|
Somatostatin Receptor
|
Neurological Disease
Metabolic Disease
Cancer
|
AP102 is a dual SSTR2/SSTR5-specific somatostatin analog (SSA). AP102 is a disulfide-bridged octapeptide SSA containing synthetic iodinated amino acids. AP102 binds with subnanomolar affinity to SSTR2 and SSTR5 (IC50: 0.63 and 0.65 nM, respectively). AP102 does not bind to SSTR1 or SSTR3. AP102 can be used for acromegaly and neuroendocrine tumors research .
|
-
- HY-P5362A
-
|
Radionuclide-Drug Conjugates (RDCs)
Somatostatin Receptor
|
Cancer
|
NODAGA-LM3 TFA can be labeled by 68Ga for PET imaging. 68Ga-NODAGA-LM3 TFA is a SSTR2 antagonist, and can be used for imaging of SSTR positive paragangliomas. NODAGA-LM3 TFA can be labeled with [68Ga] for the synthesis/research of Radionuclide-Drug Conjugates (RDCs) .
|
-
- HY-105168
-
|
Endothelin Receptor
|
Cardiovascular Disease
|
TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage .
|
-
- HY-P4070
-
|
Peptides
|
Metabolic Disease
|
Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec can be used for the research of type 2 diabetes .
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- HY-105055
-
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Peptides
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Cancer
|
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum. Didemnin B can be used for the research of cancer .
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- HY-K1046
-
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L-glutamine is an important amino acid supplement commonly added to mammalian cell culture media. L-glutamine serves as an auxiliary energy source, especially when cells are rapidly dividing. L-glutamine is also important in the production of purine and pyrimidine nucleotides, amino sugars, glutathione, L-glutamate, other amino acids, and plays a role in protein synthesis and glucose production.
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-N0733S3
-
|
Glucosamine-6- 13C (hydrochloride) is the 13C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as
|
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-
- HY-N0733S4
-
|
Glucosamine- 15N (hydrochloride) is the 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a
|
-
-
- HY-N0733S
-
|
Glucosamine- 13C (hydrochloride) is the 13C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a
|
-
-
- HY-N0733S1
-
|
Glucosamine-2- 13C (hydrochloride) is the 13C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as
|
-
-
- HY-N0733S2
-
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Glucosamine- 13C, 15N (hydrochloride) is the 13C and 15N labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, i
|
-
-
- HY-113407CS
-
|
D-Fructose-6-phosphate disodium monohydrate- 13C6 is the 13C-labeled D-Fructose-6-phosphate disodium monohydrate (HY-113407C). D-Fructose-6-phosphate disodium monohydrate is an intermediate of Glycolysis. D-Fructose-6-phosphate disodium monohydrate is the precursor for the synthesis of amino sugars, such as galactosamine and glucosamine .
|
-
-
- HY-B1125S
-
|
Glucosamine- 13C6 (D-Glucosamine- 13C6) is 13C labeled Glucosamine. Glucosamine (D-Glucosamine) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .
|
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