Search Result

Results for "

TfR

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Transferrin Receptor (16) ADC Linker (1) Amyloid-β (1) Antibody-Oligonucleotide Conjugates (AOCs) (3) Ferroptosis (3) Liposome (8) Reactive Oxygen Species (ROS) (2) Small Interfering RNA (siRNA) (5) VDAC (1)
By Research Areas:	Cancer (17) Infection (2) Inflammation/Immunology (4) Metabolic Disease (2) Neurological Disease (5)
Click Chemistry:	Azide (1)
Oligonucleotides:	Pegylated Lipids (6) Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (2) Antisense Oligonucleotides (1) siRNAs (5)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Click Chemistry

Oligonucleotides

Targets Recommended: Transferrin Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-159569

TfR-1-IN-1	Transferrin Receptor Ferroptosis	Cancer
TfR-1-IN-1 (compound C4) is an inhibitor of transferrin receptor 1 (TfR-1) with anticancer activity. TfR-1-IN-1 strongly increases intracellular iron (II) levels as a driving force for the induction of ferroptosis. TfR-1-IN-1 significantly reduces the metabolic activity of ovarian cancer (A2780cis), breast cancer (MDA-MB 231), and leukemia (HL-60) cell lines with IC₅₀ values of 0.51, 0.46, and 0.48 μM, respectively .

HY-P2297

TfR-T12	Transferrin Receptor	Metabolic Disease
TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range .

HY-P2297A

TfR-T12 TFA	Transferrin Receptor	Metabolic Disease
TfR-T12 TFA is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range .

HY-P990129

*Anti-Mouse CD71/TfR1 Antibody (8D3)*	Transferrin Receptor	Infection
Anti-Mouse CD71/TfR1 Antibody (8D3) is a rat-derived anti-mouse CD71/TfR1 IgG2a type antibody inhibitor. Anti-Mouse CD71/TfR1 Antibody (8D3) depletes of CD71+ erythroid cells but does not change percentages of Tregs in neonatal mice. Anti-Mouse CD71/TfR1 Antibody (8D3) enhances neonatal mice defence against infection .

HY-RS21441

Tfr2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tfr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tfr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tfr2 Mouse Pre-designed siRNA Set A Tfr2 Mouse Pre-designed siRNA Set A

HY-RS14430

TFR2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TFR2 Human Pre-designed siRNA Set A contains three designed siRNAs for TFR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TFR2 Human Pre-designed siRNA Set A TFR2 Human Pre-designed siRNA Set A

HY-RS27959

Tfr2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tfr2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tfr2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tfr2 Rat Pre-designed siRNA Set A Tfr2 Rat Pre-designed siRNA Set A

HY-RS14431

TFRC Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TFRC Human Pre-designed siRNA Set A contains three designed siRNAs for TFRC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TFRC Human Pre-designed siRNA Set A TFRC Human Pre-designed siRNA Set A

HY-RS16743

Tfrc Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Tfrc Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tfrc gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tfrc Mouse Pre-designed siRNA Set A Tfrc Mouse Pre-designed siRNA Set A

HY-P11099

Cys-LT7	Transferrin Receptor	Cancer
Cys-LT7 is a Cys-modified analog of LT7 peptide. LT7 (HAIYPRH) is a *TfR* homing peptide with binding site for TfR distinct from that of Tf. Cys-LT7 can be used to construct TfR-targeted drug delivery systems .

HY-P990130

*Anti-Mouse/Rat CD71/TfR1 Antibody (OX-26)*	Transferrin Receptor	Neurological Disease
Anti-Mouse/Rat CD71/TfR1 Antibody (OX-26) is a mouse-derived IgG2a κ type antibody, targeting to mouse/rat *CD71/TfR1. Anti-Mouse/Rat CD71/TfR1* Antibody (OX-26) targets the transferrin receptor and binds to an extracellular domain for the transferrin receptor. Anti-Mouse/Rat CD71/TfR1 Antibody (OX-26) can be used for the research in drug delivery, especially for drug delivery to the brain .

HY-P990791

*Anti-Mouse CD71/TfR1 Antibody (R17 217.1.3)*	Transferrin Receptor	Infection Inflammation/Immunology Cancer
Anti-Mouse CD71/TfR1 Antibody (R17 217.1.3) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse *CD71/TfR1. Anti-Mouse CD71/TfR1* Antibody (R17 217.1.3) can deplete CD71 ⁺ cells and inhibit transferrin receptor. Anti-Mouse CD71/TfR1 Antibody (R17 217.1.3) can be used for the researches of cancer, infection, inflammation and immunology, such as lung cancer, lymphocytic choriomeningitis virus (LCMV) infection and Cardiac allograft .

HY-P991047

*Anti-CD71/TfR1 Antibody* JR-141 antibody (uncoupled from iduronate 2-sulfatase)	Transferrin Receptor	Neurological Disease Cancer
Anti-CD71/TfR1 Antibody (JR-141 antibody (uncoupled from iduronate 2-sulfatase)) is a humanized anti-human transferrin receptor (CD71; TfR) antibody. Anti-CD71/TfR1 Antibody is the antibody part of the fusion protein Pabinafusp alfa (HY-P99797). The recommend isotype control of Anti-CD71/TfR1 Antibody: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P991381

*JST-TfR09* PPMX-T003	Transferrin Receptor Reactive Oxygen Species (ROS) Ferroptosis	Cancer
TXB4 (PPMX-T003) is a human monoclonal antibody (mAb) targeting CD71. JST-TfR09 can induce ferroptosis by reducing ferritin levels in ATLL cell lines, increasing the generation of ferrous iron and reactive oxygen species (ROS), and inducing lipid peroxidation via malondialdehyde. JST-TfR09 can be used in leukemia research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-172690A

DSPE-PEG3400-THRPPMWSPVWP	Liposome	Cancer
DSPE-PEG3400-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .

HY-172691

DSPE-PEG5000-THRPPMWSPVWP	Liposome	Cancer
DSPE-PEG5000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .

HY-172689

DSPE-PEG1000-THRPPMWSPVWP	Liposome	Cancer
DSPE-PEG1000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .

HY-172690

DSPE-PEG2000-THRPPMWSPVWP	Liposome	Cancer
DSPE-PEG2000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .

HY-P10928A

BCY17901	Transferrin Receptor	Neurological Disease Cancer
BCY17901 is a potent irreversible transferrin receptor 1 (TfR1) inhibitor (K_i=12 nM). BCY17901 inhibits TfR1-mediated endocytosis and iron transport, and suppresses the proliferation of tumor cells dependent on iron metabolism. BCY17901 can be used in the research of solid tumors (such as breast cancer, glioblastoma) and neurodegenerative diseases .

HY-P10928

BCY17901 TFA	Transferrin Receptor	Neurological Disease Cancer
BCY17901 TFA is a potent irreversible transferrin receptor 1 (TfR1) inhibitor (K_i=12 nM). BCY17901 TFA inhibits TfR1-mediated endocytosis and iron transport, and suppresses the proliferation of tumor cells dependent on iron metabolism. BCY17901 TFA can be used in the research of solid tumors (such as breast cancer, glioblastoma) and neurodegenerative diseases .

HY-172723A

DSPE-PEG3400-T7	Liposome	Cancer
DSPE-PEG3400-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG3400-T7 can be used for drug delivery .

HY-172724

DSPE-PEG5000-T7	Liposome	Cancer
DSPE-PEG5000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG5000-T7 can be used for drug delivery .

HY-172723

DSPE-PEG2000-T7	Liposome	Cancer
DSPE-PEG2000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG2000-T7 can be used for drug delivery .

HY-172722

DSPE-PEG1000-T7	Liposome	Cancer
DSPE-PEG1000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG1000-T7 can be used for drug delivery .

HY-P2314

HAIYPRH hydrochloride	Transferrin Receptor	Cancer
HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier .

HY-177454

Basivarsen linker	ADC Linker	Others
Basivarsen linker is a linker used in HY-177452 Zeleciment basivarsen for coupling a TfR1-binding Fab (HY-P990780 Zeleciment) and an antisense oligonucleotide. Zeleciment basivarsen is an antibody-oligonucleotide conjugate (AOC) designed to target mutant nuclear myotonic dystrophy protein kinase (DMPK) RNA for RHase H-mediated degradation to correct splicing. It is used for the study of myotonic dystrophy type 1 (DM1).

HY-P9999

Trontinemab RG6102; RO-7126209	Amyloid-β	Neurological Disease
Trontinemab (RG6102) is a brain-penetrant, anti-amyloid, bispecific and humanizedized IgG1-κ antibody, targeting to Aβ plaques and transferrin receptor 1 (TFR1). Trontinemab binds to fibrillar Aβ as well as Aβ plaques triggering plaque clearance by engaging immune cells on Alzheimer disease (AD) brain sections. Trontinemab also shows specific affinity to cynomolgus and human *TFR1* .

HY-176212

Ferroptosis-IN-20	Ferroptosis VDAC Reactive Oxygen Species (ROS)	Inflammation/Immunology
Ferroptosis-IN-20 (Compound 34a) is a Ferroptosis inhibitor (EC₅₀: 24.2 nM) targeting voltage-dependent anion channel (VDAC). Ferroptosis-IN-20 inhibits VDAC oligomerization and lipid peroxidation. Ferroptosis-IN-20 reduces content of ROS, attenuates TFR1-mediated iron uptake, inhibits Fe ²⁺ level and restores glutathione (GSH) level. Ferroptosis-IN-20 alleviates Folic acid (HY-16637)-induced acute kidney injury (AKI) .

HY-177565

Delpacibart etedesiran Del-desiran; AOC 1001	Antibody-Oligonucleotide Conjugates (AOCs) Transferrin Receptor	Inflammation/Immunology
Delpacibart braxlosiran (Del-desiran), an antibody oligonucleotide conjugate (AOC), consists of a monoclonal antibody (Delpacibart) (HY-P990051) that binds to the transferrin receptor 1 (TfR1) conjugated with a siRNA targeting DMPK (DM1 protein kinase) mRNA. Delpacibart braxlosiran is used for the study of myotonic dystrophy type 1 (DM1) .

HY-P990856

Anti-CD71 Antibody (OKT-9)	Transferrin Receptor	Cancer
Anti-CD71 Antibody (OKT-9) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CD71. Anti-CD71 Antibody (OKT-9) can recognize CD71 also known as Transferrin receptor protein 1 (TfR1). Anti-CD71 Antibody (OKT-9) can be used for the detections of immunohistochemistry, immunofluorescence and flow cytometry in cancer, such as leukemia and lymphoma .

HY-177484

Rostudirsen DYNE-251 Oligomer	Transferrin Receptor Antibody-Oligonucleotide Conjugates (AOCs)	Others
Rostudirsen, one of the components of Zeleciment rostudirsen (HY-177485), is a phosphorodiamidate morpholino oligomer. Zeleciment rostudirsen consists of Rostudirsen (HY-177484) conjugated to a fragment antibody (Fab), Zeleciment (HY-P990780), which binds to the transferrin receptor 1 (TfR1) that is highly expressed in muscle. It is designed to enable targeted muscle tissue delivery and promote exon skipping in the nucleus, allowing muscle cells to create internally shortened, near full-length dystrophin protein.

HY-177566

Delpacibart braxlosiran Del-brax; AOC 1020	Antibody-Oligonucleotide Conjugates (AOCs) Transferrin Receptor	Inflammation/Immunology
Delpacibart braxlosiran (Del-brax), an antibody oligonucleotide conjugate (AOC), consists of a monoclonal antibody (Delpacibart) (HY-P990051) that binds to the transferrin receptor 1 (TfR1) conjugated with a siRNA targeting DUX4 (Double homeobox protein) mRNA. It is used for the study of Facioscapulohumeral Muscular Dystrophy (FSHD). The abnormal expression of DUX4 protein leads to changes in gene expression in muscle cells that are associated with the life-long, progressive loss of muscle function in patients with FSHD .

Cat. No.	Product Name	Type

HY-172723

DSPE-PEG2000-T7	Drug Delivery
DSPE-PEG2000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG2000-T7 can be used for drug delivery .

HY-172690A

DSPE-PEG3400-THRPPMWSPVWP	Drug Delivery
DSPE-PEG3400-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .

HY-172691

DSPE-PEG5000-THRPPMWSPVWP	Drug Delivery
DSPE-PEG5000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .

HY-172689

DSPE-PEG1000-THRPPMWSPVWP	Drug Delivery
DSPE-PEG1000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .

HY-172690

DSPE-PEG2000-THRPPMWSPVWP	Drug Delivery
DSPE-PEG2000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .

HY-172723A

DSPE-PEG3400-T7	Drug Delivery
DSPE-PEG3400-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG3400-T7 can be used for drug delivery .

HY-172724

DSPE-PEG5000-T7	Drug Delivery
DSPE-PEG5000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG5000-T7 can be used for drug delivery .

HY-172722

DSPE-PEG1000-T7	Drug Delivery
DSPE-PEG1000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG1000-T7 can be used for drug delivery .

Cat. No.	Product Name	Target	Research Area

HY-P2297

TfR-T12	Transferrin Receptor	Metabolic Disease
TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range .

HY-P2297A

TfR-T12 TFA	Transferrin Receptor	Metabolic Disease
TfR-T12 TFA is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range .

HY-P10928

BCY17901 TFA	Transferrin Receptor	Neurological Disease Cancer
BCY17901 TFA is a potent irreversible transferrin receptor 1 (TfR1) inhibitor (K_i=12 nM). BCY17901 TFA inhibits TfR1-mediated endocytosis and iron transport, and suppresses the proliferation of tumor cells dependent on iron metabolism. BCY17901 TFA can be used in the research of solid tumors (such as breast cancer, glioblastoma) and neurodegenerative diseases .

HY-P2314

HAIYPRH hydrochloride	Transferrin Receptor	Cancer
HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier .

HY-P11099

Cys-LT7	Transferrin Receptor	Cancer
Cys-LT7 is a Cys-modified analog of LT7 peptide. LT7 (HAIYPRH) is a *TfR* homing peptide with binding site for TfR distinct from that of Tf. Cys-LT7 can be used to construct TfR-targeted drug delivery systems .

HY-P10928A

BCY17901	Transferrin Receptor	Neurological Disease Cancer
BCY17901 is a potent irreversible transferrin receptor 1 (TfR1) inhibitor (K_i=12 nM). BCY17901 inhibits TfR1-mediated endocytosis and iron transport, and suppresses the proliferation of tumor cells dependent on iron metabolism. BCY17901 can be used in the research of solid tumors (such as breast cancer, glioblastoma) and neurodegenerative diseases .

Cat. No.	Product Name	Target	Research Area

HY-P990129

*Anti-Mouse CD71/TfR1 Antibody (8D3)*	Transferrin Receptor	Infection
Anti-Mouse CD71/TfR1 Antibody (8D3) is a rat-derived anti-mouse CD71/TfR1 IgG2a type antibody inhibitor. Anti-Mouse CD71/TfR1 Antibody (8D3) depletes of CD71+ erythroid cells but does not change percentages of Tregs in neonatal mice. Anti-Mouse CD71/TfR1 Antibody (8D3) enhances neonatal mice defence against infection .

HY-P990130

*Anti-Mouse/Rat CD71/TfR1 Antibody (OX-26)*	Transferrin Receptor	Neurological Disease
Anti-Mouse/Rat CD71/TfR1 Antibody (OX-26) is a mouse-derived IgG2a κ type antibody, targeting to mouse/rat *CD71/TfR1. Anti-Mouse/Rat CD71/TfR1* Antibody (OX-26) targets the transferrin receptor and binds to an extracellular domain for the transferrin receptor. Anti-Mouse/Rat CD71/TfR1 Antibody (OX-26) can be used for the research in drug delivery, especially for drug delivery to the brain .

HY-P991047

*Anti-CD71/TfR1 Antibody* JR-141 antibody (uncoupled from iduronate 2-sulfatase)	Transferrin Receptor	Neurological Disease Cancer
Anti-CD71/TfR1 Antibody (JR-141 antibody (uncoupled from iduronate 2-sulfatase)) is a humanized anti-human transferrin receptor (CD71; TfR) antibody. Anti-CD71/TfR1 Antibody is the antibody part of the fusion protein Pabinafusp alfa (HY-P99797). The recommend isotype control of Anti-CD71/TfR1 Antibody: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-P9999

Trontinemab RG6102; RO-7126209	Amyloid-β	Neurological Disease
Trontinemab (RG6102) is a brain-penetrant, anti-amyloid, bispecific and humanizedized IgG1-κ antibody, targeting to Aβ plaques and transferrin receptor 1 (TFR1). Trontinemab binds to fibrillar Aβ as well as Aβ plaques triggering plaque clearance by engaging immune cells on Alzheimer disease (AD) brain sections. Trontinemab also shows specific affinity to cynomolgus and human *TFR1* .

HY-P990856

Anti-CD71 Antibody (OKT-9)	Transferrin Receptor	Cancer
Anti-CD71 Antibody (OKT-9) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CD71. Anti-CD71 Antibody (OKT-9) can recognize CD71 also known as Transferrin receptor protein 1 (TfR1). Anti-CD71 Antibody (OKT-9) can be used for the detections of immunohistochemistry, immunofluorescence and flow cytometry in cancer, such as leukemia and lymphoma .

HY-P990791

*Anti-Mouse CD71/TfR1 Antibody (R17 217.1.3)*	Transferrin Receptor	Infection Inflammation/Immunology Cancer
Anti-Mouse CD71/TfR1 Antibody (R17 217.1.3) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse *CD71/TfR1. Anti-Mouse CD71/TfR1* Antibody (R17 217.1.3) can deplete CD71 ⁺ cells and inhibit transferrin receptor. Anti-Mouse CD71/TfR1 Antibody (R17 217.1.3) can be used for the researches of cancer, infection, inflammation and immunology, such as lung cancer, lymphocytic choriomeningitis virus (LCMV) infection and Cardiac allograft .

HY-P991381

*JST-TfR09* PPMX-T003	Transferrin Receptor Reactive Oxygen Species (ROS) Ferroptosis	Cancer
TXB4 (PPMX-T003) is a human monoclonal antibody (mAb) targeting CD71. JST-TfR09 can induce ferroptosis by reducing ferritin levels in ATLL cell lines, increasing the generation of ferrous iron and reactive oxygen species (ROS), and inducing lipid peroxidation via malondialdehyde. JST-TfR09 can be used in leukemia research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

Species:	Human (7) Mouse (7) Rat (2) Cynomolgus (3) Pig (2)
Tag:	His (14) Tag Free (1) Avi (6) Fc (6)
Source:	HEK293 (21)

Cat. No.	Compare	Product Name	Species	Source

HY-P72455

	TFRC Protein, Mouse (HEK293, His) Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; CD71; TfRc	Mouse	HEK293
	TFRC is a key protein in cellular iron uptake, coordinating receptor-mediated endocytosis of the ligand transferrin into specialized endosomes, where endosomal acidification triggers iron release.TFRC actively regulates T and B cell proliferation through iron uptake.TFRC Protein, Mouse (HEK293, His) is the recombinant mouse-derived TFRC protein, expressed by HEK293 , with N-8*His labeled tag.

HY-P71069

	TFRC Protein, Human (HEK293, His) 1 Publications Verification Transferrin receptor protein 1; TR; TfR; Trfr; T9; p90	Human	HEK293
	TFRC protein promotes cellular iron uptake through receptor-mediated endocytosis. TFRC is essential for erythroid and nervous system development and plays a crucial role in iron homeostasis. TFRC Protein, Human (HEK293, His) is the recombinant human-derived TFRC protein, expressed by HEK293 , with N-6*His labeled tag.

HY-P74526

	TFRC Protein, Human (HEK293, hFc) Transferrin receptor protein 1; TR; TfR; Trfr; T9; p90	Human	HEK293
	TFRC protein promotes cellular iron uptake through receptor-mediated endocytosis. TFRC is essential for erythroid and nervous system development and plays a crucial role in iron homeostasis. TFRC Protein, Human (HEK293, hFc) is the recombinant human-derived TFRC protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P77855

	TFRC Protein, Cynomolgus (HEK293, His) TR; TfR1; CD71; sTfR; T9; p90; TfRC; TfR	Cynomolgus	HEK293
	TFRC is a key protein in cellular iron uptake, coordinating receptor-mediated endocytosis of the ligand transferrin into specialized endosomes, where endosomal acidification triggers iron release. TFRC actively regulates T and B cell proliferation through iron uptake. TFRC Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived TFRC protein, expressed by HEK293 , with N-His labeled tag.

HY-P78523

	TFRC Protein, Human (HEK293, His-Avi) TR; TfR1; CD71; sTfR; T9; p90; TfRC; TfR	Human	HEK293
	TFRC protein promotes cellular iron uptake through receptor-mediated endocytosis. TFRC is essential for erythroid and nervous system development and plays a crucial role in iron homeostasis. TFRC Protein, Human (HEK293, His-Avi) is the recombinant human-derived TFRC protein, expressed by HEK293 , with N-His, N-Avi labeled tag.

HY-P700841

	TFRC Protein, Human (Biotinylated, HEK293, His-Avi) TR; TfR1; CD71; sTfR; T9; p90; TfRC; TfR	Human	HEK293
	TFRC protein promotes cellular iron uptake through receptor-mediated endocytosis. TFRC is essential for erythroid and nervous system development and plays a crucial role in iron homeostasis. TFRC Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived TFRC protein, expressed by HEK293 , with C-Avi, N-His labeled tag.

HY-P78904

	TFRC Protein, Cynomolgus (Biotinylated, HEK293, His) CD71; TfRC; TfR; sTfR; TfR1; Trfr; T9; p90	Cynomolgus	HEK293
	TFRC proteins mediate iron uptake by triggering receptor-mediated endocytosis of ligand-occupied transferrin receptors, followed by acidification and iron release. It is essential for red blood cell and nervous system development, and for maintaining iron balance. TFRC Protein, Cynomolgus (Biotinylated, HEK293, His) is the recombinant cynomolgus-derived TFRC protein, expressed by HEK293 , with N-His labeled tag.

HY-P701303

	TFRC Protein, Mouse (Biotinylated, HEK293, His) CD71; TfRC; TfR; sTfR; TfR1; Trfr; T9; p90	Mouse	HEK293
	TFRC is a key protein in cellular iron uptake, coordinating receptor-mediated endocytosis of the ligand transferrin into specialized endosomes, where endosomal acidification triggers iron release.TFRC actively regulates T and B cell proliferation through iron uptake.TFRC Protein, Mouse (Biotinylated, HEK293, His) is the recombinant mouse-derived TFRC protein, expressed by HEK293 , with His labeled tag.

HY-P704917

	TFRC Protein, Mouse (HEK293, Fc) Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; CD71; TfRc	Mouse	HEK293

HY-P705097

	TFRC Protein, Human (Biotinylated, HEK293, Fc-Avi) TR; TfR1; CD71; sTfR; T9; p90; TfRC; TfR	Human	HEK293

HY-P705204

	TFRC Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) CD71; TfRC; TfR; sTfR; TfR1; Trfr; T9; p90	Cynomolgus	HEK293

HY-P705277

	TFRC Protein, Mouse (Biotinylated, HEK293, His-Avi) CD71; TfRC; TfR; sTfR; TfR1; Trfr; T9; p90	Mouse	HEK293

HY-P705163

	TFRC Protein, Rat (Biotinylated, HEK293, His-Avi) Transferrin receptor protein 1; TfRc; TR; TfR; TfR1; Trfr; CD71	Rat	HEK293

HY-P704915

	TFRC Protein, Human (HEK293) Transferrin receptor protein 1; TR; TfR; Trfr; T9; p90	Human	HEK293

HY-P704916

	TFRC Protein, Human (672a.a, HEK293, His) Transferrin receptor protein 1; TR; TfR; Trfr; T9; p90	Human	HEK293

HY-P78783

	Transferrin R2 Protein, Mouse (HEK293, mFc) Transferrin R2; TfR2	Mouse	HEK293
	The transferrin R2 protein is a key player in iron-independent cellular uptake of transferrin-bound iron, underscoring its role in delicate iron metabolism. Among other things, it may have crucial effects on liver cell function and red blood cell differentiation. Transferrin R2 Protein, Mouse (HEK293, mFc) is the recombinant mouse-derived Transferrin R2 protein, expressed by HEK293 , with N-mFc labeled tag.

HY-P73453

	Transferrin Protein, Mouse (HEK293, His) Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF	Mouse	HEK293
	Transferrin is an important iron-binding transport protein that combines two Fe(3+) ions with an anion, usually bicarbonate.Its main function is to transport iron from the site of absorption to the site of storage and utilization.Transferrin Protein, Mouse (HEK293, His) is the recombinant mouse-derived Transferrin protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P73454

	Transferrin Protein, Rat (HEK293, His) Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF	Rat	HEK293
	Transferrin is an important iron-binding transport protein that combines two Fe(3+) ions with an anion, usually bicarbonate. Its primary function is to transport iron from the site of absorption and heme degradation to the site of storage and utilization. Transferrin Protein, Rat (HEK293, His) is the recombinant rat-derived Transferrin protein, expressed by HEK293 , with C-His labeled tag.

HY-P73581

	Transferrin Protein, Mouse (HEK293, Fc) Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF	Mouse	HEK293
	Transferrin is an important iron-binding transport protein that combines two Fe(3+) ions with an anion, usually bicarbonate.Its main function is to transport iron from the site of absorption to the site of storage and utilization.Transferrin Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Transferrin protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P74494

	Transferrin Protein, Pig (HEK293, His) Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF	Pig	HEK293
	Transferrin is an important iron-binding transport protein that binds two Fe(3+) ions, usually with anions such as bicarbonate. Crucially, it transports iron from the site of absorption and heme degradation to the site of storage and utilization. Transferrin Protein, Pig (HEK293, His) is the recombinant pig-derived Transferrin protein, expressed by HEK293 , with C-His labeled tag.

HY-P74495

	Transferrin Protein, Pig (HEK293, hFc) Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF	Pig	HEK293
	Transferrin is an important iron-binding transport protein that binds two Fe(3+) ions, usually with anions such as bicarbonate. Crucially, it transports iron from the site of absorption and heme degradation to the site of storage and utilization. Transferrin Protein, Pig (HEK293, hFc) is the recombinant pig-derived Transferrin protein, expressed by HEK293 , with C-hFc labeled tag.

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HY-P86512

	Transferrin Receptor Antibody (YA6204) Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; T9; p90; CD antigen CD71; [Cleaved into: Transferrin receptor protein 1, serum form; sTfR; ]	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Transferrin Receptor Antibody (YA6204) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transferrin Receptor.

HY-P82100

	Transferrin Receptor 2 Antibody (YA1845) HFE3; TfR2; TfRC2	WB, IHC-P	Human
	Transferrin Receptor 2 Antibody (YA1845) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transferrin Receptor 2.

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HY-P10928

BCY17901 TFA		Azide
BCY17901 TFA is a potent irreversible transferrin receptor 1 (TfR1) inhibitor (K_i=12 nM). BCY17901 TFA inhibits TfR1-mediated endocytosis and iron transport, and suppresses the proliferation of tumor cells dependent on iron metabolism. BCY17901 TFA can be used in the research of solid tumors (such as breast cancer, glioblastoma) and neurodegenerative diseases .

Cat. No.	Product Name		Classification

HY-172723

DSPE-PEG2000-T7		Pegylated Lipids
DSPE-PEG2000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG2000-T7 can be used for drug delivery .

HY-RS21441

Tfr2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Tfr2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tfr2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS14430

TFR2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TFR2 Human Pre-designed siRNA Set A contains three designed siRNAs for TFR2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS27959

Tfr2 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Tfr2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tfr2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS14431

TFRC Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
TFRC Human Pre-designed siRNA Set A contains three designed siRNAs for TFRC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS16743

Tfrc Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Tfrc Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tfrc gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-172691

DSPE-PEG5000-THRPPMWSPVWP		Pegylated Lipids
DSPE-PEG5000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .

HY-172689

DSPE-PEG1000-THRPPMWSPVWP		Pegylated Lipids
DSPE-PEG1000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .

HY-172690

DSPE-PEG2000-THRPPMWSPVWP		Pegylated Lipids
DSPE-PEG2000-THRPPMWSPVWP is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (THRPPMWSPVWP). THRPPMWSPVWP binds to the TfR and is subsequently internalized into TfR-expressing cells .

HY-172724

DSPE-PEG5000-T7		Pegylated Lipids
DSPE-PEG5000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG5000-T7 can be used for drug delivery .

HY-172722

DSPE-PEG1000-T7		Pegylated Lipids
DSPE-PEG1000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG1000-T7 can be used for drug delivery .

HY-177484

Rostudirsen DYNE-251 Oligomer		Antisense Oligonucleotides
Rostudirsen, one of the components of Zeleciment rostudirsen (HY-177485), is a phosphorodiamidate morpholino oligomer. Zeleciment rostudirsen consists of Rostudirsen (HY-177484) conjugated to a fragment antibody (Fab), Zeleciment (HY-P990780), which binds to the transferrin receptor 1 (TfR1) that is highly expressed in muscle. It is designed to enable targeted muscle tissue delivery and promote exon skipping in the nucleus, allowing muscle cells to create internally shortened, near full-length dystrophin protein.

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