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Isoforms Recommended:	MAP3K7/TAK1

Results for "

TAK1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Akt (7) Antibiotic (1) Apoptosis (16) Autophagy (1) Bcl-2 Family (1) Calmodulin (2) Casein Kinase (2) Caspase (2) CDK (3) Checkpoint Kinase (Chk) (2) COX (3) Endogenous Metabolite (6) ERK (6) FGFR (1) FLT3 (2) GLP Receptor (2) GPR119 (2) GSK-3 (3) IKK (2) Interleukin Related (1) IRAK (4) Isotope-Labeled Compounds (2) JAK (2) JNK (1) Kisspeptin Receptor (2) LIM Kinase (LIMK) (1) MAP3K (25) MAP4K (4) MAPKAPK2 (MK2) (2) MEK (2) Mitochondrial Metabolism (6) Na+/H+ Exchanger (NHE) (1) NF-κB (6) NO Synthase (1) p38 MAPK (6) Phosphodiesterase (PDE) (1) PI3K (1) Reactive Oxygen Species (ROS) (2) Reference Standards (2) Ribosomal S6 Kinase (RSK) (1) RIP kinase (1) ROS Kinase (6) Small Interfering RNA (siRNA) (5) Src (1) TGF-beta/Smad (2) TNF Receptor (2) VEGFR (1) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (29) Cardiovascular Disease (1) Infection (3) Inflammation/Immunology (18) Metabolic Disease (8) Neurological Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (2) Human Pre-designed siRNA Sets (2) siRNAs (5)

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-132172

TAK1-IN-2	MAP3K	Cancer
TAK1-IN-2 is a potent and selective *TAK1* inhibitor, with an IC_50> of 2 nM ^[1].

HY-115743

TAK1-IN-3	MAP3K	Cancer
TAK1-IN-3 is a potent ATP-competitive *TAK1* inhibitor.

HY-122642

TAK1-IN-4	MAP3K	Inflammation/Immunology
TAK1-IN-4 (Compound 14) is a *TAK1* inhibitor ^[1].

HY-77251

TAK1/MAP4K2 inhibitor 1 1 Publications Verification	MAP4K MAP3K	Cancer
TAK1/MAP4K2 inhibitor 1 is a potent dual TGFβ-activated kinase 1 (TAK1) and mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) inhibitor, with IC₅₀s of 41.1 nM and 18.2 nM, respectively.

HY-150612

(R)-STU104	p38 MAPK	Cancer
(R)-STU104 is a potent and orally active TAK1-MKK3 interaction inhibitor with IC₅₀s of 0.58 μM and 4.0 μM for TNF-α and MKK3 phosphorylation. (R)-STU104 suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signal pathways through binding with MKK3 and disrupting the TAK1 phosphorylating MKK3. (R)-STU104 can be used for researching ulcerative colitis ^[1].

HY-120823

PF-05381941	MAP3K p38 MAPK	Inflammation/Immunology
PF-05381941 is a potent dual inhibitor of *TAK1/p38α, with IC₅₀*s of 156 and186 nM, respectively ^[1].

HY-150612S

(R)-STU104-d6	Isotope-Labeled Compounds p38 MAPK	Cancer
(R)-STU104-d₆ is a deuterium labeled (R)-STU104 (HY-150612). (R)-STU104 is a potent and orally active TAK1-MKK3 interaction inhibitor with IC₅₀s of 0.58 μM and 4.0 μM for TNF-α and MKK3 phosphorylation. (R)-STU104 suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signal pathways through binding with MKK3 and disrupting the TAK1 phosphorylating MKK3. (R)-STU104 can be used for researching ulcerative colitis ^[1].

HY-157871

TAK1-IN-5	MAP3K	Cancer
TAK1-IN-5 (Compound 26) is an inhibitor of the transforming growth factor-β activated kinase (TAK1) with an IC₅₀ value of 55 nM. TAK1-IN-5 can inhibit the growth of MPC-11 and H929 cells with a GI₅₀ lower than 30 nM. TAK1-IN-5 can be used in the study of multiple myeloma ^[1].

HY-153320

AZ-TAK1	MAP3K	Cancer
AZ-TAK1, an ATP-competitive small molecule inhibitor of *TAK1, dephosphorylates TAK1*, p38, and IκB-α in lymphoma cell lines ^[1].

HY-169949

TAK-756	MAP3K	Inflammation/Immunology
TAK-756 is a *TAK1* inhibitor with good selectivity for *IRAK1/4* and excellent intra-articular pharmacokinetic properties. TAK1 is a potential molecular target for osteoarthritis (OA) with complementary anti-catabolic and anti-inflammatory effects ^[1].

HY-15434

NG25 Maximum Cited Publications 24 Publications Verification	MAP4K MAP3K	Inflammation/Immunology Cancer
NG25 is a potent dual *TAK1* and MAP4K2 inhibitor, with IC₅₀s of 149 nM and 21.7 nM, respectively.

HY-N2435

[8]-Shogaol 3 Publications Verification	COX Apoptosis	Cancer
[8]-Shogaol, a kind of stimulating compound in ginger, has antiplatelet (IC₅₀=5 μM), anti-cancer and anti-inflammatory activity. [8]-Shogaol inhibited COX-2 (IC₅₀=17.5 μM), which led to the decline of human leukemia cells. 8-Shogaol Selective direction TAK1 sum TAK1-TAB1 (IC₅₀=5 μM), suppress IKK, Akt sum MAPK signal pathway, and reverse synovitis synovial sum Air dampness (RA).

HY-147141

HS-276	IRAK TNF Receptor Casein Kinase	Inflammation/Immunology
HS-276 is an orally active, potent and highly selective *TAK1* inhibitor, with a K_i of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC₅₀ values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 can be used for rheumatoid arthritis (RA) research ^[1].

HY-15434R

NG25 (Standard)	MAP4K MAP3K	Inflammation/Immunology Cancer
NG25 (Standard) is the analytical standard of NG25. This product is intended for research and analytical applications. NG25 is a potent dual TAK1 and MAP4K2 inhibitor, with IC50s of 149 nM and 21.7 nM, respectively.

HY-N2435R

[8]-Shogaol (Standard)	Reference Standards COX Apoptosis	Cancer
-Shogaol (Standard) is the analytical standard of -Shogaol. This product is intended for research and analytical applications. -Shogaol, a kind of stimulating compound in ginger, has antiplatelet (IC₅₀=5 μM), anti-cancer and anti-inflammatory activity. -Shogaol inhibited COX-2 (IC₅₀=17.5 μM), which led to the decline of human leukemia cells. 8-Shogaol Selective direction TAK1 sum TAK1-TAB1 (IC₅₀=5 μM), suppress IKK, Akt sum MAPK signal pathway, and reverse synovitis synovial sum Air dampness (RA) ^[1] .

HY-12686

5Z-7-Oxozeaenol Maximum Cited Publications 24 Publications Verification FR148083; L783279; LL-Z 1640-2	MAP3K VEGFR Antibiotic	Infection Inflammation/Immunology
5Z-7-Oxozeaenol is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of *TAK1* and VEGF-R2, with IC₅₀s of 8 nM and 52 nM, respectively.

HY-103490

Takinib 20+ Cited Publications EDHS-206	MAP3K Apoptosis	Infection Inflammation/Immunology Cancer
Takinib (EDHS-206) is an orally active and selective *TAK1* inhibitor (IC₅₀=9.5 nM), more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. Takinib is an inhibitor of autophosphorylated TAK1 that non-competitively binds within the ATP binding pocket. Takinib induces apoptosis following TNFα stimulation in cell models of rheumatoid arthritis and metastatic breast cancer. Takinib is also a P. falciparum protein kinase 9 (PfPK9) inhibitor (K_D(app) of 0.46 μM) ^[1] .

HY-N15315

Triptriolide	Apoptosis MAP3K NF-κB	Others
Triptriolide inhibits Puromycin aminonucleoside PAN (HY-15695)-induced apoptosis in mouse podocytes through regulation of Bcl-2 family proteins and inhibition of Caspase-3. Triptriolide promotes the cell survival, protects and restores the podocyte function through activation of *TAK1-NF-κB* signaling pathway and upregulation of podocin ^[1].

HY-15434A

NG25 trihydrochloride	MAP3K MAP4K	Cancer
NG25 trihydrochloride is a dual *TAK1* and MAP4K2 inhibitor (IC₅₀: 149 nM and 21.7 nM respectively). NG25 sensitizes the breast cancer cells to Doxorubicin (HY-15142A), and enhances apoptosis. NG25 trihydrochloride can be used for research of various cancers ^[1] .

HY-103490R

Takinib (Standard) EDHS-206 (Standard)	Reference Standards MAP3K Apoptosis	Infection Inflammation/Immunology Cancer
Takinib (Standard) is the analytical standard of Takinib. This product is intended for research and analytical applications. Takinib (EDHS-206) is an orally active and selective TAK1 inhibitor (IC50=9.5 nM), more than 1.5 log more potent than the second and third ranked targets, IRAK4 (120 nM) and IRAK1 (390 nM), respectively. Takinib is an inhibitor of autophosphorylated TAK1 that non-competitively binds within the ATP binding pocket. Takinib induces apoptosis following TNFα stimulation in cell models of rheumatoid arthritis and metastatic breast cancer. Takinib is also a P. falciparum protein kinase 9 (PfPK9) inhibitor (KD(app) of 0.46 μM) ^[1] .

HY-W995241

BPD	COX NF-κB	Inflammation/Immunology
BPD is a COX-2 and *TAK1-NF-κB* inhibitor, with an IC₅₀ of 18.5 μM for COX-2. BPD inhibits the expression of iNOS, TNF-α, IL-6 and IL-1β at the transcriptional level. BPD has anti-inflammatory activity. BPD can inhibit Carrageenan-induced paw oedema and LPS-induced septic death ^[1].

HY-114454

INH14 5 Publications Verification	IKK	Inflammation/Immunology Cancer
INH14 is a cell permeable inhibitor of IKKα/IKKβ, with IC₅₀s of 8.97 and 3.59 μM, respectively. INH14 inhibits the IKKα/β-dependent TLR inflammatory response. INH14 also inhibits downstream of TAK1/TAB1 and NF-kB pathways. Anti-inflammatory and anti-cancer activity ^[1].

HY-115630

cRIPGBM chloride	RIP kinase Caspase Apoptosis	Cancer
cRIPGBM chloride, an orally active, proapoptotic derivative. cRIPGBM can be generated from glioblastoma multiforme (GBM) cancer stem cells (CSCs). cRIPGBM(chloride) targets to receptor-interacting protein kinase 2 (RIPK2) to induce caspase 1-dependent apoptosis. cRIPGBM(chloride) suppresses the formation of *RIPK2/TAK1* (prosurvival complex), and increases the formation of RIPK2/caspase 1 (proapoptotic complex). cRIPGBM(chloride) exerts potent anti-tumor activity in vivo in animal models ^[1].

HY-134911

HS-243	IRAK CDK	Inflammation/Immunology Cancer
HS-243 is a potent and selective IRAK-4 and *IRAK-1* inhibitor, with IC₅₀ values of 20 and 24 nM. HS-243 shows minimal *TAK1* (transforming growth factor β-activated kinase 1) inhibition activity, with a IC₅₀ of 0.5 μM. HS-243 shows anti-inflammatory and anticancer activity ^[1].

HY-151365

IRAK4-IN-22	IRAK	Inflammation/Immunology
IRAK4-IN-22 (compound 18) is an orally active, potent and selective IRAK4 inhibitor with IC₅₀ values of 3 and 17 nM for IRAK4 and *TAK1, respectively. IRAK4-IN-21 effectively inhibits IL-23 production (IC₅₀*=0.10 µM) and can be used in studies of autoimmune diseases such as plaque psoriasis and psoriatic arthritis ^[1].

HY-151363

IRAK4-IN-21	IRAK	Inflammation/Immunology
IRAK4-IN-21 (compound 17) is an orally active, potent and selective IRAK4 inhibitor with IC₅₀ values of 5 and 56 nM for IRAK4 and *TAK1, respectively. IRAK4-IN-21 effectively inhibits IL-23 production (IC₅₀*=0.17 μM) and can be used in studies of autoimmune diseases such as plaque psoriasis and psoriatic arthritis ^[1].

HY-N1904

4′-Hydroxywogonin 8-Methoxyapigenin	IKK NF-κB p38 MAPK PI3K Akt Reactive Oxygen Species (ROS) Interleukin Related TNF Receptor Apoptosis Caspase Bcl-2 Family	Cardiovascular Disease Inflammation/Immunology Cancer
4′-Hydroxywogonin (8-Methoxyapigenin), a flavonoid, could be isolated from a variety of plants including Scutellaria barbata and Verbena littoralis. 4′-Hydroxywogonin has anti-inflammatory activity via TAK1/IKK/NF-κB, MAPKs and PI3/AKT signaling pathways. 4′-Hydroxywogonin inhibits angiogenesis by disrupting PI3K/AKT signaling. 4′-Hydroxywogonin inhibits cell proliferation and induces apoptosis ^[1] .

HY-16129A

CBP-501 acetate	Calmodulin MAP3K MAPKAPK2 (MK2) Checkpoint Kinase (Chk)	Cancer
CBP-501 acetate, a cell-permeable calmodulin-binding peptide and a G2-abrogating drug candidate, inhibits the activity of multiple Ser ²¹⁶-specific kinases, such as MAPKAP-K2, *C-Tak1, CHK1* and CHK2, with IC₅₀ values of 0.9 μM, 1.4 μM 3.4 μM and 6.5 μM, respectively. CBP-501 acetate is used for various types of cancer ^[1] .

HY-16129

CBP-501	Calmodulin Checkpoint Kinase (Chk) MAPKAPK2 (MK2) MAP3K	Cancer
CBP-501, a cell-permeable calmodulin-binding peptide and a G2-abrogating drug candidate, inhibits the activity of multiple Ser ²¹⁶-specific kinases, such as MAPKAP-K2, *C-Tak1, CHK1* and CHK2, with IC₅₀ values of 0.9 μM, 1.4 μM 3.4 μM and 6.5 μM, respectively. CBP-501 is used for various types of cancer ^[1] .

HY-W011121

2-Oleoylglycerol 2-OG	GPR119 NF-κB TGF-beta/Smad GLP Receptor	Metabolic Disease
2-Oleoylglycerol (2-OG) is a lipid found in the diet. It is a GPR119 agonist, with an EC₅₀ value of 2.5 μM in activating hGPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol enhances the inflammatory response of macrophages and promotes fibrosis by activating the *GPR119/TAK1/NF-κB/TGF-β1* signaling pathway. It also stimulates glucagon-like peptide 1 (GLP-1) secretion in vivo. 2-Oleoylglycerol is expected to be used in the research of non-alcoholic steatohepatitis (NASH) ^[1] .

HY-D0885

Phosphocreatine 2 Publications Verification Creatine phosphate; Creatinephosphoric acid	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase	Metabolic Disease
Phosphocreatine (creatine phosphate) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine enhances antioxidant activity, and activates the *TAK1* pathway to protect the heart. Phosphocreatine normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-D0885C

Phosphocreatine dipotassium Creatine phosphate dipotassium; Creatinephosphoric acid dipotassium	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase	Metabolic Disease
Phosphocreatine (creatine phosphate) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine enhances antioxidant activity, and activates the *TAK1* pathway to protect the heart. Phosphocreatine normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-N6969A

Dicentrine hydrochloride	Adrenergic Receptor	Cancer
Dicentrine hydrochloride is a drug with anti-inflammatory and anti-cancer activity. Dicentrine hydrochloride exerts its effects by enhancing TNF-α-induced apoptosis in A549 lung adenocarcinoma cells. Dicentrine hydrochloride increases caspase-8, -9, -3 and poly(ADP-ribose) polymerase (PARP) activities. Dicentrine hydrochloride inhibits TNF-α-induced invasion and migration of A549 cells. Dicentrine hydrochloride significantly inhibited the TNF-α-activated TAK1, p38, JNK and Akt signaling pathways, and reduced the transcriptional activities of NF-κB and AP-1 ^[1].

HY-D0885B

Phosphocreatine disodium 2 Publications Verification Disodium creatine phosphate	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase	Metabolic Disease
Phosphocreatine (disodium) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium) enhances antioxidant activity, and activates the *TAK1* pathway to protect the heart. Phosphocreatine (disodium) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-N0753

Eupalinolide B	Others Apoptosis Autophagy Reactive Oxygen Species (ROS) GSK-3 β-catenin MAP3K JNK NF-κB p38 MAPK	Neurological Disease Inflammation/Immunology Cancer
Eupalinolide B is a germ sesquiterpene. Eupalinolide B can be isolated from Eupatorium lindleyanum. Eupalinolide B induces Apoptosis, elevates ROS, promotes Autophagy. regulates GSK-3β/β-catenin, targets UBE2D3 and *TAK1, activates ROS-ER-JNK, inhibits NF-κB* and MAPKs. Eupalinolide B has anticancer activity against pancreatic cancer and liver cancer. Eupalinolide B relieves rheumatoid arthritis, acute lung injury, periodontitis, depression ^[1] .

HY-145015

Tuspetinib HM43239	FLT3 Apoptosis	Cancer
Tuspetinib (HM43239) is an orally active and selective FLT3 inhibitor with IC₅₀s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. Tuspetinib inhibits the kinase activity of FLT3 as a reversible type I inhibitor and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. Tuspetinib inhibits the proliferation and induces the apoptosis of leukemic cells ^[1] .

HY-145015A

Tuspetinib hydrate HM43239 hydrate	FLT3 Apoptosis	Cancer
Tuspetinib (HM43239) hydrate is an orally active and selective FLT3 inhibitor with IC₅₀s of 1.1 nM, 1.8 nM and 1.0 nM for FLT3 WT, FLT3 internal tandem duplication (ITD) and FLT3 D835Y kinases, respectively. Tuspetinib hydrate inhibits the kinase activity of FLT3 as a reversible type I inhibitor and modulates p-STAT5, p-ERK, SYK, JAK1/2, and TAK1. Tuspetinib hydrate inhibits the proliferation and induces the apoptosis of leukemic cells ^[1] .

HY-D0885D

Phosphocreatine disodium hydrate 2 Publications Verification	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase	Metabolic Disease
Phosphocreatine (disodium hydrate) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium hydrate) enhances antioxidant activity, and activates the *TAK1* pathway to protect the heart. Phosphocreatine (disodium hydrate) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium hydrate) Phosphocreatine (disodium hydrate) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-D0885R

Phosphocreatine (Standard)	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase	Metabolic Disease
Phosphocreatine (Standard) is the analytical standard of Phosphocreatine. This product is intended for research and analytical applications. Phosphocreatine (creatine phosphate) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine enhances antioxidant activity, and activates the TAK1 pathway to protect the heart. Phosphocreatine normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-W701772

2-Oleoylglycerol-d5 2-OG-d₅	Isotope-Labeled Compounds GPR119 TGF-beta/Smad NF-κB GLP Receptor	Metabolic Disease
2-Oleoylglycerol-d₅ (2-OG-d₅) is the deuterium labeled 2-Oleoylglycerol (HY-W011121). 2-Oleoylglycerol (2-OG) is a lipid found in the diet. It is a GPR119 agonist, with an EC₅₀ value of 2.5 μM in activating hGPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol enhances the inflammatory response of macrophages and promotes fibrosis by activating the GPR119/TAK1/NF-κB/TGF-β1 signaling pathway. It also stimulates glucagon-like peptide 1 (GLP-1) secretion in vivo. 2-Oleoylglycerol is expected to be used in the research of non-alcoholic steatohepatitis (NASH) ^[1] .

HY-D0885BR

Phosphocreatine disodium (Standard)	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase	Metabolic Disease
Phosphocreatine (disodium) (Standard) is the analytical standard of Phosphocreatine (disodium). This product is intended for research and analytical applications. Phosphocreatine (disodium) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium) enhances antioxidant activity, and activates the TAK1 pathway to protect the heart. Phosphocreatine (disodium) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-15504A

RGB-286638 free base 2 Publications Verification	CDK GSK-3 MEK JAK	Cancer
RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC₅₀s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3β, TAK1, Jak2 and MEK1, with IC₅₀s of 3, 5, 50, and 54 nM.

HY-136848

SM1-71	MAP3K Src FGFR Ribosomal S6 Kinase (RSK) LIM Kinase (LIMK)	Cancer
SM1-71 (compound 5) is a potent *TAK1* inhibitor, with a K_i of 160 nM, it also can covalently inhibit MKNK2, *MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1* and RSK2. SM1-71 can inhibit proliferation of multiple cancer cell lines ^[1] .

HY-15504

RGB-286638 2 Publications Verification	CDK GSK-3 MEK JAK	Cancer
RGB-286638 is a CDK inhibitor that inhibits the kinase activity of cyclin T1-CDK9, cyclin B1-CDK1, cyclin E-CDK2, cyclin D1-CDK4, cyclin E-CDK3, and p35-CDK5 with IC₅₀s of 1, 2, 3, 4, 5 and 5 nM, respectively; also inhibits GSK-3β, TAK1, Jak2 and MEK1, with IC₅₀s of 3, 5, 50, and 54 nM.

HY-RS08064

MAP3K7 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MAP3K7 Rat Pre-designed siRNA Set A contains three designed siRNAs for MAP3K7 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

MAP3K7 Rat Pre-designed siRNA Set A MAP3K7 Rat Pre-designed siRNA Set A

HY-RS09537

NR2C2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NR2C2 Human Pre-designed siRNA Set A contains three designed siRNAs for NR2C2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NR2C2 Human Pre-designed siRNA Set A NR2C2 Human Pre-designed siRNA Set A

HY-RS08063

Map3k7 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Map3k7 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Map3k7 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Map3k7 Mouse Pre-designed siRNA Set A Map3k7 Mouse Pre-designed siRNA Set A

HY-RS22687

Nr2c2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Nr2c2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nr2c2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Nr2c2 Mouse Pre-designed siRNA Set A Nr2c2 Mouse Pre-designed siRNA Set A

HY-RS08062

MAP3K7 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
MAP3K7 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP3K7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MAP3K7 Human Pre-designed siRNA Set A MAP3K7 Human Pre-designed siRNA Set A

HY-N10156

1,3,5-Trihydroxy-4-prenylxanthone	Na+/H+ Exchanger (NHE) Phosphodiesterase (PDE) NO Synthase	Inflammation/Immunology
1,3,5-Trihydroxy-4-prenylxanthone is a Na ⁺/H ⁺ exchange system (Na+/H+ Exchanger (NHE)) inhibitor with a minimum inhibitory concentration of 10 μg/mL ^[1]. 1,3,5-Trihydroxy-4-prenylxanthone is a phosphodiesterase type 5 (PDE5) (Phosphodiesterase (PDE)) inhibitor with an IC₅₀ value of 3.0 μM . 1,3,5-Trihydroxy-4-prenylxanthone inhibits Lipopolysaccharide (LPS) (Lipopolysaccharides (HY-D1056))-induced NO production in RAW264.7 macrophages, and has anti-inflammatory activities .

Cat. No.	Product Name	Target	Research Area

HY-16129A

CBP-501 acetate	Calmodulin MAP3K MAPKAPK2 (MK2) Checkpoint Kinase (Chk)	Cancer
CBP-501 acetate, a cell-permeable calmodulin-binding peptide and a G2-abrogating drug candidate, inhibits the activity of multiple Ser ²¹⁶-specific kinases, such as MAPKAP-K2, *C-Tak1, CHK1* and CHK2, with IC₅₀ values of 0.9 μM, 1.4 μM 3.4 μM and 6.5 μM, respectively. CBP-501 acetate is used for various types of cancer ^[1] .

HY-16129

CBP-501	Calmodulin Checkpoint Kinase (Chk) MAPKAPK2 (MK2) MAP3K	Cancer
CBP-501, a cell-permeable calmodulin-binding peptide and a G2-abrogating drug candidate, inhibits the activity of multiple Ser ²¹⁶-specific kinases, such as MAPKAP-K2, *C-Tak1, CHK1* and CHK2, with IC₅₀ values of 0.9 μM, 1.4 μM 3.4 μM and 6.5 μM, respectively. CBP-501 is used for various types of cancer ^[1] .

HY-P2161

TAK-683	Kisspeptin Receptor	Cancer
TAK-683 is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively ^[1]. TAK-683 depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer ^[1] .

HY-P2161A

TAK-683 TFA	Kisspeptin Receptor	Cancer
TAK-683 TFA is a potent full KISS1 receptor (KISS1R) agonist (IC₅₀=170 pM) with improved metabolic stability. TAK-683 TFA is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC₅₀ values of 0.96 nM and 1.6 nM for human and rat, respectively ^[1]. TAK-683 TFA depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer ^[1] .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2435

[8]-Shogaol 3 Publications Verification	Zingiber officinale Roscoe Structural Classification Monophenols Classification of Application Fields Source classification Phenols Plants Disease Research Fields Zingiberaceae Cancer	COX Apoptosis
[8]-Shogaol, a kind of stimulating compound in ginger, has antiplatelet (IC₅₀=5 μM), anti-cancer and anti-inflammatory activity. [8]-Shogaol inhibited COX-2 (IC₅₀=17.5 μM), which led to the decline of human leukemia cells. 8-Shogaol Selective direction TAK1 sum TAK1-TAB1 (IC₅₀=5 μM), suppress IKK, Akt sum MAPK signal pathway, and reverse synovitis synovial sum Air dampness (RA).

HY-12686

5Z-7-Oxozeaenol Maximum Cited Publications 24 Publications Verification FR148083; L783279; LL-Z 1640-2	Structural Classification Natural Products Monophenols Microorganisms Classification of Application Fields Source classification Phenols Inflammation/Immunology Disease Research Fields	MAP3K VEGFR Antibiotic
5Z-7-Oxozeaenol is a natural anti-protozoan compound from fungal origin, acting as a potent irreversible and selective inhibitor of *TAK1* and VEGF-R2, with IC₅₀s of 8 nM and 52 nM, respectively.

HY-W011121

2-Oleoylglycerol 2-OG	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	GPR119 NF-κB TGF-beta/Smad GLP Receptor
2-Oleoylglycerol (2-OG) is a lipid found in the diet. It is a GPR119 agonist, with an EC₅₀ value of 2.5 μM in activating hGPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol enhances the inflammatory response of macrophages and promotes fibrosis by activating the *GPR119/TAK1/NF-κB/TGF-β1* signaling pathway. It also stimulates glucagon-like peptide 1 (GLP-1) secretion in vivo. 2-Oleoylglycerol is expected to be used in the research of non-alcoholic steatohepatitis (NASH) ^[1] .

HY-D0885

Phosphocreatine 2 Publications Verification Creatine phosphate; Creatinephosphoric acid	Structural Classification Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase
Phosphocreatine (creatine phosphate) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine enhances antioxidant activity, and activates the *TAK1* pathway to protect the heart. Phosphocreatine normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-D0885B

Phosphocreatine disodium 2 Publications Verification Disodium creatine phosphate	Structural Classification Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase
Phosphocreatine (disodium) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium) enhances antioxidant activity, and activates the *TAK1* pathway to protect the heart. Phosphocreatine (disodium) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-N2435R

[8]-Shogaol (Standard)	Zingiber officinale Roscoe Structural Classification Monophenols Source classification Phenols Plants Zingiberaceae	Reference Standards COX Apoptosis
-Shogaol (Standard) is the analytical standard of -Shogaol. This product is intended for research and analytical applications. -Shogaol, a kind of stimulating compound in ginger, has antiplatelet (IC₅₀=5 μM), anti-cancer and anti-inflammatory activity. -Shogaol inhibited COX-2 (IC₅₀=17.5 μM), which led to the decline of human leukemia cells. 8-Shogaol Selective direction TAK1 sum TAK1-TAB1 (IC₅₀=5 μM), suppress IKK, Akt sum MAPK signal pathway, and reverse synovitis synovial sum Air dampness (RA) ^[1] .

HY-N15315

Triptriolide	Triterpenes Structural Classification Terpenoids Source classification Celastraceae Tripterygium wilfordii Hook. f. Plants	Apoptosis MAP3K NF-κB
Triptriolide inhibits Puromycin aminonucleoside PAN (HY-15695)-induced apoptosis in mouse podocytes through regulation of Bcl-2 family proteins and inhibition of Caspase-3. Triptriolide promotes the cell survival, protects and restores the podocyte function through activation of *TAK1-NF-κB* signaling pathway and upregulation of podocin ^[1].

HY-N1904

4′-Hydroxywogonin 8-Methoxyapigenin	Structural Classification Flavonoids Flavones Verbenaceae Verbena littoralis H.B.K. Plants	IKK NF-κB p38 MAPK PI3K Akt Reactive Oxygen Species (ROS) Interleukin Related TNF Receptor Apoptosis Caspase Bcl-2 Family
4′-Hydroxywogonin (8-Methoxyapigenin), a flavonoid, could be isolated from a variety of plants including Scutellaria barbata and Verbena littoralis. 4′-Hydroxywogonin has anti-inflammatory activity via TAK1/IKK/NF-κB, MAPKs and PI3/AKT signaling pathways. 4′-Hydroxywogonin inhibits angiogenesis by disrupting PI3K/AKT signaling. 4′-Hydroxywogonin inhibits cell proliferation and induces apoptosis ^[1] .

HY-D0885C

Phosphocreatine dipotassium Creatine phosphate dipotassium; Creatinephosphoric acid dipotassium	Structural Classification Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase
Phosphocreatine (creatine phosphate) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine enhances antioxidant activity, and activates the *TAK1* pathway to protect the heart. Phosphocreatine normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-N6969A

Dicentrine hydrochloride	Structural Classification Alkaloids Other Alkaloids Source classification Stephania epigaea Lo Plants Menispermaceae	Adrenergic Receptor
Dicentrine hydrochloride is a drug with anti-inflammatory and anti-cancer activity. Dicentrine hydrochloride exerts its effects by enhancing TNF-α-induced apoptosis in A549 lung adenocarcinoma cells. Dicentrine hydrochloride increases caspase-8, -9, -3 and poly(ADP-ribose) polymerase (PARP) activities. Dicentrine hydrochloride inhibits TNF-α-induced invasion and migration of A549 cells. Dicentrine hydrochloride significantly inhibited the TNF-α-activated TAK1, p38, JNK and Akt signaling pathways, and reduced the transcriptional activities of NF-κB and AP-1 ^[1].

HY-N0753

Eupalinolide B	Structural Classification Classification of Application Fields Melilotus albus Desr. Terpenoids Sesquiterpenes Source classification Plants Compositae Disease Research Fields Cancer	Others Apoptosis Autophagy Reactive Oxygen Species (ROS) GSK-3 β-catenin MAP3K JNK NF-κB p38 MAPK
Eupalinolide B is a germ sesquiterpene. Eupalinolide B can be isolated from Eupatorium lindleyanum. Eupalinolide B induces Apoptosis, elevates ROS, promotes Autophagy. regulates GSK-3β/β-catenin, targets UBE2D3 and *TAK1, activates ROS-ER-JNK, inhibits NF-κB* and MAPKs. Eupalinolide B has anticancer activity against pancreatic cancer and liver cancer. Eupalinolide B relieves rheumatoid arthritis, acute lung injury, periodontitis, depression ^[1] .

HY-D0885D

Phosphocreatine disodium hydrate 2 Publications Verification	Structural Classification Animals Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase
Phosphocreatine (disodium hydrate) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium hydrate) enhances antioxidant activity, and activates the *TAK1* pathway to protect the heart. Phosphocreatine (disodium hydrate) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium hydrate) Phosphocreatine (disodium hydrate) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-D0885R

Phosphocreatine (Standard)	Structural Classification Animals Ketones, Aldehydes, Acids Source classification Endogenous metabolite	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase
Phosphocreatine (Standard) is the analytical standard of Phosphocreatine. This product is intended for research and analytical applications. Phosphocreatine (creatine phosphate) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine enhances antioxidant activity, and activates the TAK1 pathway to protect the heart. Phosphocreatine normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-D0885BR

Phosphocreatine disodium (Standard)	Structural Classification Source classification Amino acids Endogenous metabolite	Endogenous Metabolite MAP3K Akt Mitochondrial Metabolism ERK Apoptosis ROS Kinase
Phosphocreatine (disodium) (Standard) is the analytical standard of Phosphocreatine (disodium). This product is intended for research and analytical applications. Phosphocreatine (disodium) is an organic compound found in vertebrate skeletal muscles. Phosphocreatine (disodium) enhances antioxidant activity, and activates the TAK1 pathway to protect the heart. Phosphocreatine (disodium) normalizing mitochondrial function and reducing oxidative stress via Akt mediated Nrf2/HO-1 pathway. Phosphocreatine (disodium) provides renal protection by suppressing Apoptosis and ROS (Reactive Oxygen Species) generation through ERK mediated mediated Nrf-2/HO-1 pathway. ^[1] .

HY-N10156

1,3,5-Trihydroxy-4-prenylxanthone	Flavonoids Leguminosae Source classification Plants Other Flavonoids Erythrina variegata Linn.	Na+/H+ Exchanger (NHE) Phosphodiesterase (PDE) NO Synthase
1,3,5-Trihydroxy-4-prenylxanthone is a Na ⁺/H ⁺ exchange system (Na+/H+ Exchanger (NHE)) inhibitor with a minimum inhibitory concentration of 10 μg/mL ^[1]. 1,3,5-Trihydroxy-4-prenylxanthone is a phosphodiesterase type 5 (PDE5) (Phosphodiesterase (PDE)) inhibitor with an IC₅₀ value of 3.0 μM . 1,3,5-Trihydroxy-4-prenylxanthone inhibits Lipopolysaccharide (LPS) (Lipopolysaccharides (HY-D1056))-induced NO production in RAW264.7 macrophages, and has anti-inflammatory activities .

Species:	Human (3)
Tag:	His (1) Tag Free (2)
Source:	Sf9 insect cells (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P703591

	TAK1 Protein, Human (sf9) TAK1	Human	Sf9 insect cells
	TAK1 Protein, Human (sf9) is the recombinant human-derived TAK1, expressed by sf9 insect cells , with tag Free labeled tag. ,

HY-P701640

	TAB1 Protein, Human TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1	Human	E. coli
	The TAB1 protein is a key adapter that activates JNK, NF-kappa-B, and proinflammatory cytokines in response to TLR and cytokine stimulation. It binds to MAP3K7/TAK1, inducing autophosphorylation and full activation. TAB1 Protein, Human is the recombinant human-derived TAB1 protein, expressed by E. coli , with tag free.

HY-P701639

	TAB1 Protein, Human (His) TAB1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1	Human	E. coli
	The TAB1 protein is a key adapter that activates JNK, NF-kappa-B, and proinflammatory cytokines in response to TLR and cytokine stimulation. It binds to MAP3K7/TAK1, inducing autophosphorylation and full activation. TAB1 Protein, Human (His) is the recombinant human-derived TAB1 protein, expressed by E. coli , with N-6*His labeled tag.

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Cat. No.	Product Name	Chemical Structure

HY-150612S

(R)-STU104-d6

(R)-STU104-d₆ is a deuterium labeled (R)-STU104 (HY-150612). (R)-STU104 is a potent and orally active TAK1-MKK3 interaction inhibitor with IC₅₀s of 0.58 μM and 4.0 μM for TNF-α and MKK3 phosphorylation. (R)-STU104 suppresses the TAK1/MKK3/p38/MnK1/MK2/elF4E signal pathways through binding with MKK3 and disrupting the TAK1 phosphorylating MKK3. (R)-STU104 can be used for researching ulcerative colitis ^[1].

HY-W701772

2-Oleoylglycerol-d5

2-Oleoylglycerol-d₅ (2-OG-d₅) is the deuterium labeled 2-Oleoylglycerol (HY-W011121). 2-Oleoylglycerol (2-OG) is a lipid found in the diet. It is a GPR119 agonist, with an EC₅₀ value of 2.5 μM in activating hGPR119 in transiently transfected COS-7 cells. 2-Oleoylglycerol enhances the inflammatory response of macrophages and promotes fibrosis by activating the GPR119/TAK1/NF-κB/TGF-β1 signaling pathway. It also stimulates glucagon-like peptide 1 (GLP-1) secretion in vivo. 2-Oleoylglycerol is expected to be used in the research of non-alcoholic steatohepatitis (NASH) ^[1] .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P80355

	TAK1 Antibody (YA042)	WB	Human, Mouse, Rat, Monkey
	TAK1 Antibody (YA042) is a non-conjugated and Rabbit origined monoclonal antibody about 67 kDa, targeting to TAK1. It can be used for WB assays with tag free, in the background of Human, Mouse, rat, monkey.

HY-P80908

	TAK1 Antibody (YA663) 1 Publications Verification MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1	WB	Human, Mouse, Rat, Monkey
	TAK1 Antibody (YA663) is a non-conjugated and Mouse origined monoclonal antibody about 67 kDa, targeting to TAK1 (3G1). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.

HY-P80858

	*Phospho-TAK1* (Ser439) Antibody (YA144)** 1 Publications Verification MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1	WB, ICC/IF, IP	Human, Mouse, Rat
	Phospho-TAK1 (Ser439) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 67 kDa, targeting to Phospho-TAK1 (Ser439). It can be used for WB,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P82656

	TAB3 Antibody (YA2401) MAP3K7IP 3; NAP1; NFkB activating protein 1; Tab3; TAK1 binding protein 3	WB, ICC/IF	Human, Mouse
	TAB3 Antibody (YA2401) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2401), targeting TAB3, with a predicted molecular weight of 79 kDa (observed band size: 90 kDa). TAB3 Antibody (YA2401) can be used for WB, ICC/IF experiment in human, mouse background.

HY-P86498

	TAK1 Antibody (YA6190) MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	TAK1 Antibody (YA6190) is a rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TAK1. It can be applicated for WB, ICC/IF, IP, ELISA assays, in the background of human, mouse, rat.

HY-P82206

	TAB1 Antibody (YA1951) MAP3K7IP1; TAB1; TAK1 binding protein 1	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	TAB1 Antibody (YA1951) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1951), targeting TAB1, with a predicted molecular weight of 55 kDa (observed band size: 60 kDa). TAB1 Antibody (YA1951) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P85540

	TAB1(N-term) Antibody (YA5232) 2310012M03Rik; 3'-Tab1; MAP3K7IP 1; MAP3K7IP1; MGC57664; Mitogen activated protein kinase kinase kinase 7 interacting protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TAB 1; TAB1; TAB1_HUMAN; TAK1 binding protein 1; TAK1-binding protein 1; TGF beta activated kinase 1 binding protein 1; TGF-beta activated kinase 1/MAP3K7 binding protein 1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; TGF-beta-activated kinase 1-binding protein 1; Transforming growth factor beta activated kinase binding protein 1.	WB	Human
	TAB1(N-term) Antibody (YA5232) is a mouse-derived and non-conjugated monoclonal antibody, targeting to TAB1 (N-term). It can be applicated for WB assays, in the background of human.

HY-P85471

	TAB1 Antibody (YA5163) TAB1; MAP3K7IP1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1	WB	Human, Mouse, Rat, Bovine, Dog, Pig
	TAB1 Antibody (YA5163) is a mouse-derived and non-conjugated monoclonal antibody, targeting to TAB1. It can be applicated for WB assays, in the background of human, mouse, rat, bovine, dog, pig.

HY-P85382

	TAB2 Antibody (YA5074) TAB2; KIAA0733; MAP3K7IP2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAK1-binding protein 2; TAB-2; TGF-beta-activated kinase 1-binding protein 2	WB, FC, ELISA	Human
	TAB2 Antibody (YA5074) is a mouse-derived and non-conjugated monoclonal antibody, targeting to TAB2. It can be applicated for WB, FC, ELISA assays, in the background of human.

HY-P82405

	MARK3 Antibody (YA2150) C-TAK1 antibody; Cdc25C associated protein kinase 1 antibody; Cdc25C-associated protein kinase 1 antibody; cTAK1 antibody; ELKL motif kinase 2 antibody; EMK-2 antibody; Emk2 antibody; ETK 1 antibody; KIAA4230 antibody; KP78 antibody; MAP microtubule affinity regulating kinase 3 antibody; MAP/microtubule affinity-regulating kinase 3 antibody; Mark3 antibody; MARK3_HUMAN antibody; Par 1a antibody; PAR1A antibody; Protein kinase STK10 antibody; Ser/Thr protein kinase PAR-1 antibody; Serine threonine protein kinase p78 antibody; Serine/threonine-protein kinase p78 antibody; SerThr protein kinase PAR 1 antibody;	WB, ICC/IF, IP, FC	Mouse, Human
	MARK3 Antibody (YA2150) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2150), targeting MARK3, with a predicted molecular weight of 84 kDa (observed band size: 84 kDa). MARK3 Antibody (YA2150) can be used for WB, ICC/IF, IP, FC experiment in mouse, human background.