Search Result

Results for "

T-ALL

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (6) Bcl-2 Family (1) Bcr-Abl (1) Calcium Channel (1) Discoidin Domain Receptor (1) DNA Alkylator/Crosslinker (1) Drug Metabolite (1) EAAT (1) Glucocorticoid Receptor (1) Histone Acetyltransferase (1) Histone Demethylase (5) Methylenetetrahydrofolate Dehydrogenase (MTHFD) (1) Molecular Glues (1) Notch (4) Nucleoside Antimetabolite/Analog (2) PROTACs (2) Reference Standards (1) SHMT (1) Src (3) γ-secretase (1)
By Research Areas:	Cancer (22) Inflammation/Immunology (1) Neurological Disease (3)

By Targets:

Apoptosis (6)

Bcl-2 Family (1)

Bcr-Abl (1)

Calcium Channel (1)

Discoidin Domain Receptor (1)

DNA Alkylator/Crosslinker (1)

Drug Metabolite (1)

EAAT (1)

Glucocorticoid Receptor (1)

Histone Acetyltransferase (1)

Histone Demethylase (5)

Methylenetetrahydrofolate Dehydrogenase (MTHFD) (1)

Molecular Glues (1)

Notch (4)

Nucleoside Antimetabolite/Analog (2)

PROTACs (2)

Reference Standards (1)

SHMT (1)

Src (3)

γ-secretase (1)

By Research Areas:

Cancer (22)

Inflammation/Immunology (1)

Neurological Disease (3)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-13701

Nelarabine 2 Publications Verification 506U78; GW 506U78; Nelzarabine	Nucleoside Antimetabolite/Analog Apoptosis	Cancer
Nelarabine (506U78) is a nucleoside analogue and can be used for the research of T cell acute lymphoblastic leukemia (T-ALL) .

HY-136522

S2116	Histone Demethylase Apoptosis	Cancer
S2116, a N-alkylated tranylcypromine (TCP) derivative, is a potent lysine-specific demethylase 1 (LSD1) inhibitor. S2116 increases H3K9 methylation and reciprocal H3K27 deacetylation at super-enhancer regions. S2116 induces apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by repressing transcription of the NOTCH3 and TAL1 genes. S2116 significantly retardes the growth of T-ALL cells in xenotransplanted mice .

HY-136523

S2157	Histone Demethylase Apoptosis	Cancer
S2157, a N-alkylated tranylcypromine (TCP) derivative, is a potent lysine-specific demethylase 1 (LSD1) inhibitor. S2157 increases H3K9 methylation and reciprocal H3K27 deacetylation at super-enhancer regions. S2157 induces apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by repressing transcription of the NOTCH3 and TAL1 genes. S2157 efficiently pass through the blood-brain barrier and can almost completely eradicate CNS leukemia in mice transplanted with T-ALL cells .

HY-14174

MRK-560	γ-secretase	Neurological Disease Cancer
MRK-560, a chemical probe, is an orally active, brain barrier-penetrated γ-Secretase inhibitor, reducing Aβ peptide in rat brain and cerebrospinal fluid. MRK-560 decreases mutant NOTCH1 processing by selectively inhibiting PSEN1. MRK-560 can be used in studies of Alzheimer's disease and T-cell acute lymphoblastic leukaemia (T-ALL) .

HY-118858

UCPH-102	EAAT	Neurological Disease Cancer
UCPH-102 is a highly selective EAAT1 inhibitor with an IC₅₀ of 0.43 µM. UCPH-102 exhibits a specific anti-proliferative effect on T-ALL cells. UCPH-102 also shows good blood-brain permeability, which can be used in studies of amyotrophic lateral sclerosis, Alzheimer’s disease, chronic pain and obsessive compulsive disorder .

HY-134978A

(+)SHIN2 2 Publications Verification	SHMT	Cancer
(+)SHIN2 is a serine hydroxymethyltransferase (SHMT) inhibitor, whose target can be traced with ¹³C-serine. (+)SHIN2 increases survival in NOTCH1-driven mouse primary acute lymphoblastic leukemia (T-ALL) in vivo with a synergistic effect with Methotrexate (HY-14519) . (+)SHIN2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-175281

SJ11646	PROTACs Src Discoidin Domain Receptor Bcr-Abl Apoptosis	Cancer
SJ11646 is a Dasatinib (HY-10181)-based LCK PROTAC degrader with a DC₅₀ of 0.00838 pM. SJ11646 has potent cytotoxicity against LCK-activated T-cell acute lymphoblastic leukemia (T-ALL) cells and primary leukemia samples with drastically prolonged suppression of LCK signaling, and induces T-ALL apoptosis. SJ11646 binds to 51 human kinases with a high affinity (particularly ABL1, KIT, and DDR1). SJ11646 has superior antileukemic efficacy in T-ALL mice model. . Pink: LCK ligand (HY-107447); Blue: CRBN ligase ligand (HY-163169); Black: linker (HY-76667)

HY-164466

CAD204520	Calcium Channel Notch	Cancer
CAD204520, a SERCA inhibitor (IC₅₀ = 0.34 μM), targets mutated over wild type NOTCH1 proteins in T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL) .

HY-175280

Lck degrader-1	Molecular Glues Src	Cancer
Lck degrader-1 (Compound 17) is a molecular glue degrader targeting lymphocyte-specific protein tyrosine kinase (LCK) (DC₅₀=23.1 nM). Lck degrader-1 is promising for research of T-cell acute lymphoblastic leukemia (T-ALL) .

HY-13701R

Nelarabine (Standard) 506U78 (Standard); GW 506U78 (Standard); Nelzarabine (Standard)	Reference Standards Nucleoside Antimetabolite/Analog Apoptosis	Cancer
Nelarabine (Standard) is the analytical standard of Nelarabine. This product is intended for research and analytical applications. Nelarabine (506U78) is a nucleoside analogue and can be used for the research of T cell acute lymphoblastic leukemia (T-ALL) .

HY-176244

KI-TOX-A3	Histone Acetyltransferase	Cancer
KI-TOX-A3 is a selective protein-protein interaction (PPI) inhibitor targeting TOX protein (with an IC₅₀ value of 0.51 μM for TOX-KAT7 interaction). KI-TOX-A3 induces proteasomal degradation of TOX, restores KAT7-mediated H3K14 acetylation, reversing CD8 ⁺ T cell exhaustion and inhibiting T-cell acute lymphoblastic leukemia (T-ALL) cell proliferation. KI-TOX-A3 is promising for research of hematological tumors (e.g., T-ALL) .

HY-P991328

MAb604.107	Notch	Cancer
MAb604.107 is a human monoclonal antibody (mAb) targeting NOTCH1. MAb604.107 inhibits the proliferation and CD34/CD44 expression of primary T-ALL cells. MAb604.107 has anti-tumor activity in four tumor xenograft mouse models: MDA-MB-231, HCC-1806, BT-474, and HCT-116. MAb604.107 can be used in T acute lymphoblastic leukemia research .

HY-14572

PR-104A SN 27858	DNA Alkylator/Crosslinker Drug Metabolite	Cancer
PR-104A (SN 27858) is the alcohol metabolite of phosphate proagent PR-104. PR-104A is a hypoxia-selective DNA cross-linking agent/DNA-damaging agent and cytotoxin. Antitumor Activity . PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase. PR-104A can be used for the research of relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL) .

HY-155188

NWP-0476	Bcl-2 Family	Neurological Disease
NWP-0476 is BCL-2/BCL-xL inhibitor. NWP-0476 has a modified structure with fine-tuned BCL-xL activity. NWP-0476 can be used for relapsed T-acute lymphoblastic leukemia (T-ALL) research .

HY-162676

SJ45566	PROTACs Src	Cancer
SJ45566 a potent and orally active PROTAC-based LCK degrader, with a DC₅₀ of 1.21 nM. SJ45566 can be used in the research for T‑Cell Acute Lymphoblastic Leukemia .

HY-12419

BMS-983970	Notch	Cancer
BMS-983970 is an oral pan-Notch inhibitor for the treatment of multiplecancers .

HY-155219

TH9028	Methylenetetrahydrofolate Dehydrogenase (MTHFD)	Cancer
TH9028 is an inhibitor of MTHFD2 (IC₅₀ = 11 nM) with IC₅₀ values against hMTHFD2, MTHFD2L, and MTHFD1 being 7.97 nM, 27 nM, and 0.5 nM, respectively. TH9028 also exhibits anti-cancer cell proliferation activity .

HY-112255

J9	Glucocorticoid Receptor	Cancer
J9 is a small molecule that reverses Dexamethasone (HY-14648) resistance in T-cell acute lymphoblastic leukemia. J9 is lethal to CUTLL1 cells only in the presence of Dexamethasone. J9 inhibits CUTLL1 cell growth with an EC₅₀ of 28 μM in combination with Dexamethasone .

HY-151194

LSD1/2-IN-4	Histone Demethylase	Cancer
LSD1/2-IN-4, a PCPA derivative, is an inhibitor of lysine-specific demethylase 1 (LSD1) and lysine-specific demethylase 2 (LSD2). LSD1/2-IN-4 inhibits LSD1 and LSD2 with K_i values of 0.11 μM and 130 μM, respectively. LSD1/2-IN-4 can be used for the research of several cancers including T-cell acute lymphoblastic leukemia (TALL) .

HY-121662

Lenaldekar LDK	Apoptosis	Inflammation/Immunology Cancer
Lenaldekar (LDK) inhibits human and murine T-cell expansiomn. Lenaldekar inhibits autoimmune T cell response. Lenaldekar also induces cancer cell apoptosis. Lenaldekar can be used for T-cell mediated autoimmune diseases research .

HY-137471

RBPJ Inhibitor-1 5 Publications Verification RIN1	Notch	Cancer
RBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation .

HY-151190

cis-4-Br-2,5-F2-PCPA S1024	Histone Demethylase	Cancer
cis-4-Br-2,5-F2-PCPA (S1024) is a selective inhibitor of lysine-specific demethylase 1 (LSD1), with a K_i value of 94 nM instead of 8.4 μM for LSD2. There is aberrant expression of LSD1 in cancer stem cells, cis-4-Br-2,5-F2-PCPA inhibits LSD1 cell proliferation and by increasing the level of dimethylated histone H3 at K4 (H3K4) in CCRF-CEM cells .

HY-151192

LSD1/2-IN-3	Histone Demethylase	Cancer
LSD1/2-IN-3 is a selective inhibitor of lysine-specific demethylase 1 (LSD1), with a K_i value of 11 nM instead of 7 μM for LSD2. There is aberrant expression of LSD1 in cancer stem cells, LSD1/2-IN-1 inhibits LSD1 cell proliferation .

Cat. No.	Product Name	Target	Research Area

HY-P991328

MAb604.107	Notch	Cancer
MAb604.107 is a human monoclonal antibody (mAb) targeting NOTCH1. MAb604.107 inhibits the proliferation and CD34/CD44 expression of primary T-ALL cells. MAb604.107 has anti-tumor activity in four tumor xenograft mouse models: MDA-MB-231, HCC-1806, BT-474, and HCT-116. MAb604.107 can be used in T acute lymphoblastic leukemia research .

Species:	Human (17) Mouse (6) Cynomolgus (5) Canine (1)
Tag:	His (16) SUMO (1) Tag Free (2) Avi (11) Fc (11) Flag (7)
Source:	HEK293 (24) CHO (1) E. coli (4)

Cat. No.	Compare	Product Name	Species	Source

HY-P77571

	BAFF/TNFSF13B Trimer Protein, Cynomolgus (HEK293, His-Avi) BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Cynomolgus	HEK293
	BAFF/TNFSF13B protein is a member of the TNF family and regulates immune responses and cell survival. It is also known as B cell activating factor, which plays a vital role in the development, activation and survival of B cells by binding to receptors such as BAFF-R. BAFF/TNFSF13B Trimer Protein, Cynomolgus (HEK293, His-Avi) is the recombinant cynomolgus-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-His, N-Avi labeled tag.

HY-P78384

	BAFF/TNFSF13B Trimer Protein, Human (HEK293, His-Flag) BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Human	HEK293
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. BAFF/TNFSF13B Trimer Protein, Human (HEK293, His-Flag) is the recombinant human-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-His, N-Flag labeled tag.

HY-P77572

	BAFF/TNFSF13B Protein, Cynomolgus (Biotinylated, HEK293, His-Flag-Avi) BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Cynomolgus	HEK293
	BAFF/TNFSF13B protein is a member of the TNF family and regulates immune responses and cell survival. It is also known as B cell activating factor, which plays a vital role in the development, activation and survival of B cells by binding to receptors such as BAFF-R. BAFF/TNFSF13B Protein, Cynomolgus (Biotinylated, HEK293, His-Flag-Avi) is the recombinant cynomolgus-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-His, N-Avi, N-Flag labeled tag.

HY-P78066

	BAFF/TNFSF13B Trimer Protein, Human (Biotinylated, HEK293, His-Avi) BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Human	HEK293
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. BAFF/TNFSF13B Trimer Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-His, N-Avi labeled tag.

HY-P7003

	BAFF/TNFSF13B Protein, Human (CHO) 1 Publications Verification rHuBAFF/TNFSF13B; BLYS; TALL1; THANK; ZTNF4; TALL-1; TNFSF20	Human	CHO
	BAFF/TNFSF13B Protein, Human (CHO) is a member of the tumor necrosis factor (TNF) superfamily, and plays an essential role in peripheral B-cell homeostasis.

HY-P700531

	BAFF/TNFSF13B Protein, Human (His-SUMO) BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Human	E. coli
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. BAFF/TNFSF13B Protein, Human (His-SUMO) is the recombinant human-derived BAFF/TNFSF13B protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

HY-P703757

	BAFF/TNFSF13B Protein, Cynomolgus (HEK293, hFc) BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Cynomolgus	HEK293
	BAFF/TNFSF13B Protein, Cynomolgus (HEK293, hFc) is the recombinant cynomolgus-derived BAFF/TNFSF13B protein, expressed by HEK293, with N-hFc tag.

HY-P78385

	BAFF/TNFSF13B Protein, Human (HEK293, Fc-Flag) BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Human	HEK293
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. BAFF/TNFSF13B Protein, Human (HEK293, Fc-Flag) is the recombinant human-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-hFc, N-Flag labeled tag.

HY-P700459

	BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, hFc-Avi) BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Human	HEK293
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, hFc-Avi) is the recombinant human-derived BAFF/TNFSF13B protein, expressed by HEK293 , with C-Avi, N-hFc labeled tag.

HY-P705471

	BAFF/TNFSF13B Trimer Protein, Human (Biotinylated, 152a.a, HEK293, His-Avi) BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1	Human	HEK293

HY-P700016AF

	Animal-Free APRIL/TNFSF13 Protein, Human (His) TNFSF13; CD256; TALL-2; TALL2; TNLG7B; TRDL-1; UNQ383/PRO715; ZTNF2	Human	E. coli
	APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture. APRIL protein has been widely used in the study of lymphatic malignancies. Human APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. Animal-Free APRIL/TNFSF13 Protein, Human (His) is produced by E. coli (A105-L250) with C-terminal His-tag.This product is for cell culture use only.

HY-P704361

	APRIL/TNFSF13 Protein, Human (HEK293, hFc) TNFSF13; CD256; TALL-2; TALL2; TNLG7B; TRDL-1; UNQ383/PRO715; ZTNF2	Human	HEK293
	APRIL/TNFSF13 is a TNF superfamily cytokine that affects tumor cell growth by binding to TNFRSF13B/TACI and TNFRSF17/BCMA receptors. Its homotrimeric structure highlights a potential role in oncogenic processes and immune functions involving monocytes and macrophages. APRIL/TNFSF13 Protein, Human (HEK293, hFc) is the recombinant human-derived APRIL/TNFSF13 protein, expressed by HEK293, with N-hFc labeled tag.

HY-P700017AF

	Animal-Free BAFF/TNFSF13B Protein, Human (His) TNFSF13B; BLYS; CD257; DTL; TALL-1; TALL1; THANK; TNFSF20; TNLG7A; ZTNF4	Human	E. coli
	BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. Animal-Free BAFF/TNFSF13B Protein, Human (His) is the recombinant human-derived animal-FreeBAFF/TNFSF13B protein, expressed by E. coli , with C-His labeled tag.This product is for cell culture use only.

HY-P705167

	BAFF/TNFSF13B Protein, Mouse (Biotinylated, HEK293, Avi-Fc) TNFSF13B; BAFF; BLYS; CD257; DTL; TALL1; THANK; TNFSF20; ZTNF4; TALL-1	Mouse	HEK293

HY-P77564

	APRIL/TNFSF13 Trimer Protein, Cynomolgus (HEK293, His-Flag-Avi) CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik	Cynomolgus	HEK293
	APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture. APRIL protein has been widely used in the study of lymphatic malignancies. APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. APRIL/TNFSF13 Trimer Protein, Cynomolgus (HEK293, His-Flag-Avi) is produced by HEK293 cells (K112-L250) with N-terminal His, Avi, and Flag tags.

HY-P704980

	APRIL/TNFSF13 Trimer Protein, Human (Biotinylated, HEK293, His-Fc) CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik	Human	HEK293

HY-P704981

	APRIL/TNFSF13 Trimer Protein, Human (Biotinylated, HEK293, His-Avi) CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik	Human	HEK293

HY-P700661

	APRIL/TNFSF13 Trimer Protein, Human (Biotinylated, HEK293, Flag, His-Avi) CD256; TALL2; TALL-2; TNFSF13; APRIL; APRILFLJ57090; TRDL1; TRDL-1; ZTNF2; 2310026N09Rik	Human	HEK293
	APRIL/TNFSF13 is a TNF superfamily cytokine that affects tumor cell growth by binding to TNFRSF13B/TACI and TNFRSF17/BCMA receptors. Its homotrimeric structure highlights a potential role in oncogenic processes and immune functions involving monocytes and macrophages. APRIL/TNFSF13 Trimer Protein, Human (Biotinylated, HEK293, Flag, His-Avi) is the recombinant human-derived APRIL/TNFSF13 protein, expressed by HEK293 , with N-Flag, C-Avi, N-His labeled tag.

HY-P7538

	APRIL/TNFSF13 Protein, Mouse (HEK293, Fc) rMuAPRIL/TNFSF13, N-Fc; CD256; TALL2; APRIL; TNFSF13	Mouse	HEK293
	APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture. APRIL protein has been widely used in the study of lymphatic malignancies. Mouse APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. APRIL/TNFSF13 Protein, Mouse (HEK293, Fc) is produced by HEK293 cells (A96-K240) with N-terminal Fc-tag.

HY-P75589

	BAFF/TNFSF13B Protein, Canine (HEK293, Fc) Tumor necrosis factor ligand superfamily member 13B; BAFF; TALL-1	Canine	HEK293
	The BAFF/TNFSF13B protein is part of the TNF family and is critical in the regulation of immune responses and cell survival. It is also called B cell activating factor and plays a crucial role in B cell development, activation and survival by binding to receptors such as BAFF-R. BAFF/TNFSF13B Protein, Canine (HEK293, Fc) is the recombinant canine-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-hFc labeled tag. The total length of BAFF/TNFSF13B Protein, Canine (HEK293, Fc) is 150 a.a., with molecular weight of ~45.5 kDa.

HY-P7839

	BCMA/TNFRSF17 Protein, Cynomolgus (HEK293, Fc) rCynBCMA-TALL_bind domain-containing protein/BCMA, Fc; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma	Cynomolgus	HEK293
	B Cell Maturation Antigen (BCMA) also referred to as TNFRSF17 or CD269, is a transmembrane glycoprotein member of the tumor necrosis factor receptor (TNFR) superfamily. BCMA is used as a biomarker for Multiple myeloma (MM). BCMA mainly plays an important role in B cells for their proliferation, survival and also differentiates them into plasma cells. BCMA/TNFRSF17 Protein, Cynomolgus (HEK293, Fc) is a recombinant protein with a C-Terminal Fc label, It consists of 53 amino acids (M1-A53) and is produced in HEK293 cells.

HY-P704315

	BAFF/TNFSF13B Protein, Mouse (HEK293) Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1	Mouse	HEK293
	BAFF/TNFSF13B protein binds to TNFRSF13B and TNFRSF17, stimulates B-cell and T-cell function and regulates humoral immunity. BAFF/TNFSF13B also interacts with TNFSF13 to promote the survival and response of mature B cells. BAFF/TNFSF13B Protein, Mouse (HEK293) is the recombinant mouse-derived BAFF/TNFSF13B protein, expressed by HEK293, with tag free.

HY-P70428

	BAFF/TNFSF13B Protein, Human (HEK293, His) Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1	Human	HEK293
	BAFF/TNFSF13B, is the B cell-activating cytokine belonging to the tumor necrosis factor family. BAFF is involved in cancer immunity and is mainly expressed in myeloid cells. Its overexpression can lead to autoimmune diseases such as systemic lupus erythematosus (SLE). In addition, BAFF is also involved in adipogenesis, atherosclerosis, neuroinflammatory process and ischemia/reperfusion (I/R) injury. Human BAFF protein has two glycosylated domains and one transmembrane domain (48-68 a.a.), and can be cleaved into membrane-type peptide fragments and soluble peptide fragments. BAFF/TNFSF13B Protein, Human (HEK293, His) is the extracullar part of BAFF protein (A134-L285), produced in HEK293 cells with N-terminal 6*His-tag.

HY-P70730

	BAFF/TNFSF13B Protein, Human (HEK293, Fc) Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1	Human	HEK293
	BAFF/TNFSF13B, is the B cell-activating cytokine belonging to the tumor necrosis factor family. BAFF is involved in cancer immunity and is mainly expressed in myeloid cells. Its overexpression can lead to autoimmune diseases such as systemic lupus erythematosus (SLE). In addition, BAFF is also involved in adipogenesis, atherosclerosis, neuroinflammatory process and ischemia/reperfusion (I/R) injury . Human BAFF protein has two glycosylated domains and one transmembrane domain (48-68 a.a.), and can be cleaved into membrane-type peptide fragments and soluble peptide fragments. BAFF/TNFSF13B Protein, Human (HEK293, Fc) is the extracullar part of BAFF protein (A134-L285), produced in HEK293 cells with N-terminal hFc-tag.

HY-P70816

	BAFF/TNFSF13B Protein, Mouse (HEK293, Fc) Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1	Mouse	HEK293
	BAFF/TNFSF13B, is the B cell-activating cytokine belonging to the tumor necrosis factor family. BAFF is involved in cancer immunity and is mainly expressed in myeloid cells. Its overexpression can lead to autoimmune diseases such as systemic lupus erythematosus (SLE). In addition, BAFF is also involved in adipogenesis, atherosclerosis, neuroinflammatory process and ischemia/reperfusion (I/R) injury . Mouse BAFF protein has two glycosylated domains and one transmembrane domain (48-68 a.a.), and can be cleaved into membrane-type peptide fragments and soluble peptide fragments. BAFF/TNFSF13B Protein, Mouse (HEK293, Fc) is the extracullar part of BAFF protein (A127-L309), produced in HEK293 cells with N-terminal mFc-tag.

HY-P700161AF

	Animal-Free BAFF/TNFSF13B Protein, Mouse (His) 1 Publications Verification Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1	Mouse	E. coli
	BAFF/TNFSF13B, is the B cell-activating cytokine belonging to the tumor necrosis factor family. BAFF is involved in cancer immunity and is mainly expressed in myeloid cells. Its overexpression can lead to autoimmune diseases such as systemic lupus erythematosus (SLE). In addition, BAFF is also involved in adipogenesis, atherosclerosis, neuroinflammatory process and ischemia/reperfusion (I/R) injury . Mouse BAFF protein has two glycosylated domains and one transmembrane domain (48-68 a.a.), and can be cleaved into membrane-type peptide fragments and soluble peptide fragments. Animal-Free BAFF/TNFSF13B Protein, Mouse (His) is the extracullar part of BAFF protein (A127-L309), produced in HEK293 cells with C-terminal His-tag.This product is for cell culture use only.

HY-P705246

	BAFF/TNFSF13B Protein, Mouse (Biotinylated, HEK293, His-Avi) Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1	Mouse	HEK293

HY-P70733

	APRIL/TNFSF13 Trimer Protein, Human (HEK293, Flag-His) Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD256; TNFSF13	Human	HEK293
	APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture. APRIL protein has been widely used in the study of lymphatic malignancies. Human APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. APRIL/TNFSF13 Protein, Human (HEK293, Flag-His) is produced by HEK293 cells (K112-L250) with N-terminal 6*His and Flag tag.

HY-P70733A

	APRIL/TNFSF13 Trimer Protein, Human (HEK293, His-Flag) Tumor necrosis factor ligand superfamily member 13; A proliferation-inducing ligand; APRIL; TNF- and APOL-related leukocyte expressed ligand 2; TALL-2; TNF-related death ligand 1; TRDL-1; CD256; TNFSF13	Human	HEK293
	APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation, regulate tumor cell growth, and may participate in mononuclear/macrophage-mediated immune process. APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture. APRIL protein has been widely used in the study of lymphatic malignancies. Human APRIL protein is a type II membrane protein with cytoplasmic domain, hydrophobic transmembrane domain and extracellular domain. APRIL/TNFSF13 Protein, Human (HEK293, His-Flag) is produced by HEK293 cells (K112-L250) with N-terminal His and Flag-tags.

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HY-P82513

	PHAPI2/APRIL Antibody (YA2258) APRIL; CD256; TALL2; TNFSF13; TRDL1; ZTNF2	WB, ICC/IF	Human, Mouse, Rat
	PHAPI2/APRIL Antibody (YA2258) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PHAPI2/APRIL.

HY-P84885

	BAFF Antibody (YA4582) DTL; BAFF; BLYS; CD257; TALL1; THANK; ZTNF4; TALL-1; TNLG7A; TNFSF20	WB, ICC/IF, FC, ELISA	Human
	BAFF Antibody (YA4582) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to BAFF.

HY-P81765

	BAFF Antibody (YA1510) TNFSF13B; BAFF; BLYS; TALL1; TNFSF20; ZTNF4; Tumor necrosis factor ligand superfamily member 13B; B lymphocyte stimulator; BLyS; B-cell-activating factor; BAFF; Dendritic cell-derived TNF-like molecule; TNF- and APOL-related leukocyte expressed ligand 1; TALL-1; CD257	FC, ELISA	Human
	BAFF Antibody (YA1510) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to BAFF.

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