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Suzuki

" in MedChemExpress (MCE) Product Catalog:

20

Inhibitors & Agonists

2

Fluorescent Dye

9

Biochemical Assay Reagents

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W019633

    Biochemical Assay Reagents Others
    Benzothiazole-5-boronic acid pinacol ester is a compound that can be used in the boronate part of Suzuki coupling reactions .
    Benzothiazole-5-boronic acid pinacol ester
  • HY-32928

    Biochemical Assay Reagents Others
    4-Cyanobenzeneboronic acid is a Boronic acid derivative. 4-Cyanobenzeneboronic acid can be used in Suzuki-Miyaura cross-coupling reactions .
    4-Cyanobenzeneboronic acid
  • HY-W001987

    Biochemical Assay Reagents Others
    Organic ligands can be prepared through Suzuki cross-coupling reaction between 4,6-Dichloropyrimidin-5-amine and dimethyl(5-pinyl)isophthalate .
    4,6-Dichloropyrimidin-5-amine
  • HY-W002849

    2-(Dicyclohexylphosphino)biphenyl

    Biochemical Assay Reagents Others
    Cyjohnphos is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Cyjohnphos can be used in combination with a nickel catalyst for the Suzuki-Miyaura arylation of tertiary benzylic acetates with aryl boroxines to produce diaryl and triaryl quaternary stereocenters .
    Cyjohnphos
  • HY-W002570

    Biochemical Assay Reagents Others
    2-Naphthylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Naphthylboronic acid can undergo silylation reaction. 2-Naphthylboronic acid also readily undergo Suzuki-Miyaura cross-coupling .
    2-Naphthylboronic acid
  • HY-W005558

    Biochemical Assay Reagents Others
    6-Aminopyridine-3-boronic acid is a boronic acid derivative. Boronic acid derivatives are widely used in organic synthesis for carbon-carbon bond formation. In Suzuki coupling, aryl halides and boronic acid aryl or vinyl esters or boronic acid are coupled using Pd(PPh3)4. It can be used as a pharmaceutical intermediate [1] .
    6-Aminopyridine-3-boronic acid
  • HY-75129

    Biochemical Assay Reagents Others
    Pyridin-3-ylboronic acid is an organic compound. Pyridin-3-ylboronic acid is a key reagent in the Suzuki-Miyaura cross-coupling reaction. Pyridin-3-ylboronic acid is used in organic synthesis to construct oligopyridine compounds, and then as an α-helix mimetic to study protein-protein interactions .
    Pyridin-3-ylboronic acid
  • HY-W244282

    Ligands for E3 Ligase Cancer
    Thalidomide-pinacolborane is a Thalidomide analogue featuring a boronic pinacol ester, otherwise known as a Bpin group, and they are most frequently used in Suzuki reactions. This molecule is an activator for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.
    Thalidomide-pinacolborane
  • HY-D2262

    Fluorescent Dye Metabolic Disease
    BODIPY-cholesterol conjugate-2 (compound 6) is a BODIPY-cholesterol conjugate. BODIPY-cholesterol conjugate-2 is a useful probe for simultaneous visualization of intracellular cholesterol pools and for monitoring cholesterol efflux from cells to extracellular acceptors. (λex=589 nm, λem=638 nm) .
    BODIPY-cholesterol conjugate-2
  • HY-D2261

    Fluorescent Dye Metabolic Disease
    BODIPY-cholesterol conjugate-1 (compound 5) is a BODIPY-cholesterol conjugate. BODIPY-cholesterol conjugate-1 is a useful probe for simultaneous visualization of intracellular cholesterol pools and for monitoring cholesterol efflux from cells to extracellular acceptors . (λex 541 nm, λem 615 nm).
    BODIPY-cholesterol conjugate-1
  • HY-101974

    Biochemical Assay Reagents Others
    Biotin-PEG3-Bromide is a short PEG linker featuring a biotin group and a bromide. The bromide is a halogen which is easily displaced by nucleophiles such as alcohols or amines. Alternatively, bromide can be applied in a number of cross-coupling reactions such as in a Suzuki reaction. Biotin is useful for affinity-based applications such as pull-down assays or for ligating with streptavidin proteins.
    Biotin-PEG3-Bromide
  • HY-42045

    Biochemical Assay Reagents Others
    Pyrimidine-5-boronic acid pinacol ester is a derivative of Boronic acid. Boronic acid is an intermediate commonly used in organic synthesis reactions and can be used as a key reagent in the Suzuki-Miyaura reaction. It generates organic free radicals through oxygen-mediated oxidation and exhibits potential mutagenic activity. Boronic acid is mainly used in research in the fields of drug synthesis and catalytic reactions. At the same time, it should be noted that it may be a genotoxic impurity (GTIs) .
    Pyrimidine-5-boronic acid pinacol ester
  • HY-114362

    TPGS-750-M

    Biochemical Assay Reagents Others
    DL-alpha-Tocopherol methoxypolyethylene glycol succinate (TPGS-750-M) is an amphiphile, acts as a surfactant. DL-alpha-Tocopherol methoxypolyethylene glycol succinate has a positive effect on Suzuki-Miyaura cross coupling. DL-alpha-Tocopherol methoxypolyethylene glycol succinate increases the styrene titer. DL-alpha-Tocopherol methoxypolyethylene glycol succinate is used in the stability test of NPYM-modified drugs in biological fluids .
    DL-alpha-Tocopherol methoxypolyethylene glycol succinate
  • HY-W001222

    Biochemical Assay Reagents Others
    3-Furanboronic acid is a 3-furanboronic acid, and furan is a π-electron heteroarene. In chemical synthesis, 3-Furanboronic acid and different 2-benzofuranboronic acids have good reactivity. 3-Furanboronic acid can successfully react with 3-bromothiophene, 2,3-bromopyridine, or 3-bromoquinoline with only a small amount of catalyst. Due to the coordination of heteroatoms with the palladium center, no poisoning effects were observed .
    3-Furanboronic acid
  • HY-W020985

    Pd(DIPHOS)2

    Biochemical Assay Reagents Others
    Bis[1,2-bis(diphenylphosphino)ethane]palladium(0), often abbreviated as Pd(PPh3)2 or Pd(dppf), is an organometallic compound. This compound is widely used as a catalyst for organic chemical reactions, especially cross-coupling reactions such as Suzuki-Miyaura reaction and Heck reaction, and its high catalytic activity, selectivity and stability make it a versatile tool for the synthesis of complex organic compounds , in addition, the potential application of Pd(PPh3)2 in the production of electronic materials and in medical and biochemical research has also been investigated.
    Bis[1,2-bis(diphenylphosphino)ethane]palladium(0)
  • HY-171854

    G2A (GPR132) Neurological Disease Inflammation/Immunology
    SB-583355 (Compound 56) is a potent G2A antagonist. SB-583355 can be prepared by a Suzuki reaction between 4-methoxyphenyl boronic acid and 3-bromo-4-hydroxybenzoic acid following the conditions followed by an amide coupling reaction. SB-583355 blocks the activation of G2A mediated either by 9-HOPE or T-10148 in human G2A expressing CHO-K1 cells. SB-583355 can be studied in research for inflammation, myeloid leukemia, and neuropathic pain .
    SB-583355
  • HY-40190

    Biochemical Assay Reagents Drug Intermediate Metabolic Disease
    5-Bromo-2,3-dihydro-1H-inden-1-one is a bromoindanone compound. 5-Bromo-2,3-dihydro-1H-inden-1-one acts as a key intermediate in organic synthesis, participating in reactions such as Suzuki coupling and Buchwald amination. 5-Bromo-2,3-dihydro-1H-inden-1-one can be used in the research of obesity-related metabolic diseases .
    5-Bromo-2,3-dihydro-1H-inden-1-one
  • HY-146489

    Bacterial Parasite Infection
    Anti-infective agent 3 (compound 3l) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 0.47 and 0.13 μM, respectively. Anti-infective agent 3 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 4 μg/mL .
    Anti-infective agent 3
  • HY-146488

    Parasite Bacterial Infection
    Anti-infective agent 2 (compound 3k) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 0.07 and 2.20 μM, respectively. Anti-infective agent 2 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 32 μg/mL .
    Anti-infective agent 2
  • HY-146487

    Bacterial Parasite Infection
    Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL .
    Anti-infective agent 1

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