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Results for "

Sonic

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

1

Peptides

3

Natural
Products

3

Recombinant Proteins

2

Isotope-Labeled Compounds

2

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100515
    Robotnikinin
    3 Publications Verification

    		 Hedgehog Inflammation/Immunology
    Robotnikinin is a small molecule capable of binding to and inhibiting the activity of Sonic Hedgehog (Shh) signaling up stream of Smo .
    Robotnikinin
  • HY-158059
    DS-1-38

    		Hedgehog Cancer
    DS-1-38 is an EYA1 antagonist that blocks Sonic Hedgehog (SHH) signaling. EYA1 is a haloacid dehalogenase phosphatase and transcription factor that regulates tumorigenesis and proliferation in SHH medulloblastoma (SHH-MB) .
    DS-1-38
  • HY-B0508
    Ornidazole
    2 Publications Verification

    Ro 7-0207

    		 Bacterial Parasite Antibiotic Hedgehog Infection Cancer
    Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
    Ornidazole
  • HY-147743
    SMO-IN-1

    		Smo Cancer
    SMO-IN-1 (Compound 15) is an orally active Smoothened (SMO) inhibitor with an EC50 of 89 nM against sonic Hh protein (shh) .
    SMO-IN-1
  • HY-147744
    AZD7254

    		Smo Cancer
    AZD7254 is an orally active Smoothened (SMO) inhibitor with an EC50 of 1.0 nM against sonic Hh protein (shh) .
    AZD7254
  • HY-162135
    MAT2A-IN-14

    		Methionine Adenosyltransferase (MAT) Reactive Oxygen Species (ROS) Cancer
    MAT2A-IN-14 (compound H3) is a MAT2A inhibitor, and generates reactive oxygen species after sonication to specifically degrade cellular MAT2A via rapid oxidative reactions. Combination of MAT2A-IN-14 and sonication induces 87% MAT2A depletion in human colon cancer cell .
    MAT2A-IN-14
  • HY-N16232
    2-ACC

    2-α-Carboxy cholestanol

    		 Hedgehog Metabolic Disease
    2-ACC (2-α-Carboxy cholestanol) is a cholestanol, is a mutant Sonic Hedgehog protein D46A activator with an EC50 of ～5 μM.
    2-ACC
  • HY-120664
    BRD50837

    		Hedgehog Cancer
    BRD50837 is a potent inhibitor of Sonic Hedgehog (Shh), with the EC50 of 0.09 μM. BRD50837 plays an important role in cancer research .
    BRD50837
  • HY-P10875
    HL2-m5

    		Hedgehog Cancer
    HL2-m5 is the inhibitor for the interaction between sonic hedgehog/patched (Shh/PTCH1) with Kd of 170 nM for Shh. HL2-m5 inhibits activation of Hedgehog signaling pathway and transcription of Gli-controlled gene with an IC50 of 230 nM .
    HL2-m5
  • HY-B0508S
    Ornidazole-d5

    Ro 7-0207-d5

    		 Isotope-Labeled Compounds Bacterial Parasite Antibiotic Hedgehog Infection Cancer
    Ornidazole-d5 is deuterium labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
    Ornidazole-d5
  • HY-116455
    BRD-9526

    		Fluorescent Dye Cancer
    BRD-9526 is a potent and selective Sonic Hedgehog (Shh) pathway inhibitor with potential anti-cancer activity. The mechanism of BRD-9526 is similar in some ways to commonly used inhibitors such as cyclopamine, but is significantly different in other ways. The discovery of BRD-9526 may provide a useful probe for studying complex signaling pathways .
    BRD-9526
  • HY-B0508R
    Ornidazole (Standard)

    Ro 7-0207 (Standard)

    		 Reference Standards Bacterial Parasite Antibiotic Hedgehog Infection Cancer
    Ornidazole (Standard) is the analytical standard of Ornidazole. This product is intended for research and analytical applications. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
    Ornidazole (Standard)
  • HY-B0508S1
    Ornidazole-13C2,15N2

    Ro 7-0207-13C2,15N2

    		 Isotope-Labeled Compounds Bacterial Parasite Antibiotic Hedgehog Infection
    Ornidazole- 13C2, 15N2 is the 13C, 15N labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease .
    Ornidazole-13C2,15N2

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