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Results for "

PTPN9

" in MedChemExpress (MCE) Product Catalog:

By Targets:	JAK (1) NF-κB (2) Phosphatase (4) Reference Standards (1) Small Interfering RNA (siRNA) (3) STAT (1) Tau Protein (2)
By Research Areas:	Cancer (3) Inflammation/Immunology (3) Metabolic Disease (2) Neurological Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Natural
Products

Recombinant Proteins

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145923

Osunprotafib 3 Publications Verification ABBV-CLS-484	Phosphatase STAT JAK	Cancer
Osunprotafib (ABBV-CLS-484) is an orally active and selective active site *PTPN1* (IC₅₀: 2.5 nM) and *PTPN2(IC₅₀*: 1.8 nM) inhibitor. Osunprotafib has 6-8-fold weaker activity on PTPN9 and no detectable activity on SHP-1 or SHP-2. Osunprotafib increases the sensitivity of human cancer cell lines to IFNγ. Osunprotafib generates robust anti-tumor immunity by enhancing JAK-STAT signalling and reducing T cell dysfunction .

HY-N4150

Quercetagitrin Quercetagetin-7-O-glucoside	Phosphatase Tau Protein NF-κB	Neurological Disease Metabolic Disease Inflammation/Immunology
Quercetagitrin (Quercetagetin-7-O-glucoside) is a natural product that can be isolated from the African marigold (Tagetes erecta). Quercetagitrin has anti-inflammatory activity. Quercetagitrin inhibits Tau accumulation. Quercetagitrin can reverse neuroinflammation and cognitive deficits in P301S-Tau transgenic mouse model through inhibiting NF-κB activation. Quercetagitrin is a dual-target inhibitor of *PTPN6* (IC₅₀ = 1 μM) and *PTPN9* (IC₅₀ = 1.7 μM). Quercetagitrin enhances glucose uptake by mature C2C12 myoblasts. Quercetagitrin can be studied in research for Alzheimer’s disease and type 2 diabetes .

HY-RS26982

Ptpn9 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ptpn9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptpn9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ptpn9 Rat Pre-designed siRNA Set A Ptpn9 Rat Pre-designed siRNA Set A

HY-RS20474

Ptpn9 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Ptpn9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptpn9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ptpn9 Mouse Pre-designed siRNA Set A Ptpn9 Mouse Pre-designed siRNA Set A

HY-RS11431

PTPN9 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PTPN9 Human Pre-designed siRNA Set A contains three designed siRNAs for PTPN9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PTPN9 Human Pre-designed siRNA Set A PTPN9 Human Pre-designed siRNA Set A

HY-145923B

Osunprotafib hydrochloride ABBV-CLS-484 hydrochloride	Phosphatase	Inflammation/Immunology Cancer
Osunprotafib (ABBV-CLS-484) hydrochloride is an orally active and selective active site *PTPN1* (IC₅₀: 2.5 nM) and *PTPN2(IC₅₀*: 1.8 nM) inhibitor. Osunprotafib hydrochloride has 6-8-fold weaker activity on PTPN9 and no detectable activity on SHP-1 or SHP-2. Osunprotafib hydrochloride increases the sensitivity of human cancer cell lines to IFNγ. Osunprotafib hydrochloride generates robust anti-tumor immunity by enhancing JAK-STAT signalling and reducing T cell dysfunction .

HY-N4150R

Quercetagitrin (Standard) Quercetagetin-7-O-glucoside (Standard)	Reference Standards Phosphatase Tau Protein NF-κB	Metabolic Disease Inflammation/Immunology Cancer
Quercetagitrin (Standard) is the analytical standard of Quercetagitrin. This product is intended for research and analytical applications. Quercetagitrin (Quercetagetin-7-O-glucoside) is a natural product that can be isolated from the African marigold (Tagetes erecta). Quercetagitrin has anti-inflammatory activity. Quercetagitrin inhibits Tau accumulation. Quercetagitrin can reverse neuroinflammation and cognitive deficits in P301S-Tau transgenic mouse model through inhibiting NF-κB activation. Quercetagitrin is a dual-target inhibitor of *PTPN6* (IC₅₀ = 1 μM) and *PTPN9* (IC₅₀ = 1.7 μM). Quercetagitrin enhances glucose uptake by mature C2C12 myoblasts. Quercetagitrin can be studied in research for Alzheimer’s disease and type 2 diabetes .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N4150

Quercetagitrin Quercetagetin-7-O-glucoside	Flavonols Structural Classification Flavonoids Classification of Application Fields Source classification Erythrina melanacantha Taub. ex Harms Phenols Polyphenols Plants Compositae Inflammation/Immunology Disease Research Fields	Phosphatase Tau Protein NF-κB
Quercetagitrin (Quercetagetin-7-O-glucoside) is a natural product that can be isolated from the African marigold (Tagetes erecta). Quercetagitrin has anti-inflammatory activity. Quercetagitrin inhibits Tau accumulation. Quercetagitrin can reverse neuroinflammation and cognitive deficits in P301S-Tau transgenic mouse model through inhibiting NF-κB activation. Quercetagitrin is a dual-target inhibitor of *PTPN6* (IC₅₀ = 1 μM) and *PTPN9* (IC₅₀ = 1.7 μM). Quercetagitrin enhances glucose uptake by mature C2C12 myoblasts. Quercetagitrin can be studied in research for Alzheimer’s disease and type 2 diabetes .

HY-N4150R

Quercetagitrin (Standard) Quercetagetin-7-O-glucoside (Standard)	Flavonols Structural Classification Flavonoids Source classification Erythrina melanacantha Taub. ex Harms Phenols Polyphenols Plants Compositae	Reference Standards Phosphatase Tau Protein NF-κB
Quercetagitrin (Standard) is the analytical standard of Quercetagitrin. This product is intended for research and analytical applications. Quercetagitrin (Quercetagetin-7-O-glucoside) is a natural product that can be isolated from the African marigold (Tagetes erecta). Quercetagitrin has anti-inflammatory activity. Quercetagitrin inhibits Tau accumulation. Quercetagitrin can reverse neuroinflammation and cognitive deficits in P301S-Tau transgenic mouse model through inhibiting NF-κB activation. Quercetagitrin is a dual-target inhibitor of *PTPN6* (IC₅₀ = 1 μM) and *PTPN9* (IC₅₀ = 1.7 μM). Quercetagitrin enhances glucose uptake by mature C2C12 myoblasts. Quercetagitrin can be studied in research for Alzheimer’s disease and type 2 diabetes .

Recombinant Proteins Recommended:

PTPN9

Cat. No.	Compare	Product Name	Species	Source

HY-P77170

	*PTP-MEG2/PTPN9* Protein, Human (sf9, His-GST)** Tyrosine-protein phosphatase non-receptor type 9; PTPase MEG2; PTPN9	Human	Sf9 insect cells
	The PTP-MEG2/PTPN9 protein is a multifunctional protein tyrosine phosphatase with potential roles related to hydrophobic ligand transfer or Golgi function. It operates in a complex cellular environment, demonstrating the versatility of different molecular processes. PTP-MEG2/PTPN9 Protein, Human (sf9, His-GST) is the recombinant human-derived PTP-MEG2/PTPN9 protein, expressed by Sf9 insect cells , with C-His, N-GST labeled tag.

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Ptpn9 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Ptpn9 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ptpn9 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ptpn9 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Ptpn9 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ptpn9 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

PTPN9 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PTPN9 Human Pre-designed siRNA Set A contains three designed siRNAs for PTPN9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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