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1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PE (18:0p/20:4-PE; C18(Plasm)-20:4-PE) is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively.
PE 22-28 is a TREK-1 inhibitor with IC50 value of 0.12 nM. PE 22-28 also is a 7 amino-acid peptide that is used as a core sequence for preparing analogs by chemical modifications and also by substitution of amino-acids. PE 22-28 can be used for the research of depression .
Prolyl Endopeptidase, highly active in brain and other tissues, catabolizes proline-containing peptides such as substance P, neurotensin, luteinizing hormone-releasing hormone, thyrotropin releasing hormone, bradykinin and angiotensin II. Prolyl Endopeptidase can be used for study of neuropsychiatric diseases such as stress disorder, depression, and schizophrenia .
PE0116 is a fully human CD137 agonistic monoclonal antibody generated from immunized harbor H2L2 human transgenic mice. PE0116 is a ligand block. PE0116 activates NF-κB signaling which significantly promotes T-cell proliferation and increases cytokine secretion in vitro. PE0116 exhibits robust antitumor activity in MC38 tumor model .
1-Stearoyl-2-eicosapentaenoyl-sn-glycero-3-PE (PE(18:0/20:5)) is a phospholipid identified in plasma lipid profile analysis, with similar lipid level changes in high-grade cervical intraepithelial neoplasia and cervical cancer compared with normal state and low-grade cervical intraepithelial neoplasia, and can be used to monitor cervical cancer progression.
1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE (18:0p/22:6-PE) is a lipid identified in rat brain tissue by mass spectrometry imaging with specific structural and distribution characteristics, and isomers of different fatty acid chains can be identified by improved methods.
1,2-Dierucoyl-sn-glycero-3-PE (1,2-Dierucoyl-sn-3-phosphatidylethanolamine) is a phospholipid that contains erucic acid. 1,2-Dierucoyl-sn-glycero-3-PE can be used in the generation of lipid nanoparticles (LNPs) to deliver mRNA in vivo. 1,2-Dierucoyl-sn-glycero-3-PE can also be used to synthesize numerous PEG-conjugates for liposomes incorporation .
PE-VF647 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. PE-VF647 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 665 nm.
PE-VF750 Maleimide is a thiol-reactive double-dye dye that contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/777 nm. PE-VF750 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 777 nm.
PE-VF680 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/701 nm. PE-VF680 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 701 nm.
PE154 (Compound 13) is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50s=280 pM and 16 nM, respectively) . PE154 can label β-amyloid plaques in histochemical analysis .
1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) and adrenic acid (HY-W013215) at the sn-1 and sn-2 positions, respectively. 1-Stearoyl-2-adrenoyl-sn-glycero-3-PE levels are inversely correlated with subject age in mitochondria isolated from human post-mortem hippocampus.
06:0 PE (PE(6:0/6:0)) is a water-soluble phospholipid characterized by its short acyl chains, exhibiting notable antitumor activity and the ability to inhibit tumor progression in vivo, alongside antiproliferative and proapoptotic effects, while serving as a precursor for phosphatidylcholine and phosphatidylethanolamine.
1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-PE; PE(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))) is an ester product.
PeS-9 is an Androgen Receptor (AR) degrader that induces androgen receptor degradation PeS-9 induces mitochondrial and ER stress by promoting cytotoxic ROS production, leading to the release of mitochondrial cytochrome C and AIF. PeS-9 subsequently activates caspases-9 and -3, causing DNA fragmentation and apoptotic cell death. PeS-9 has anticancer activity against prostate cancer and exerts in vivo antitumor and antimetastatic activity with minor side effects. PeS-9 can be used for the study of targeting monotherapy against GLUT-1-overexpressing tumors .
Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 25% of total mammalian phospholipids. In the brain, phosphatidylethanolamine comprises almost half of the total phospholipids. It is synthesized mainly through the cytidine diphosphate-ethanolamine and phosphatidylserine decarboxylation pathways, which occur in the endoplasmic reticulum (ER) and mitochondrial membranes, respectively. It is a precursor in the synthesis of phosphatidylcholine and arachidonoyl ethanolamide and is a source of ethanolamine used in various cellular functions. In E. coli, phosphatidylethanolamine deficiency prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone. It is a cofactor in the propagation of prions in vitro and can convert recombinant mammalian proteins into infectious molecules even in the absence of RNA. This product contains phosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 and sn-2 positions.
PES1 Human Pre-designed siRNA Set A contains three designed siRNAs for PES1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
PENK Human Pre-designed siRNA Set A contains three designed siRNAs for PENK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
18:0-18:2 PE is an important component of phosphatidylethanolamine (PE), involved in phospholipid metabolism and associated with diseases such as ovarian cancer. 18:0-18:2 PE in the hot processing process, its unsaturated fatty acids will degrade to form a variety of odor active compounds. 18:0-18:2 PE is mainly used in the field of food science to improve the flavor of aquatic products, as well as medical research on diseases related to phospholipid metabolism .
Bovine Sermu Albumin-PE is a biochemical reagent conjugated to fluorescein PE (Ex=565 nm; Em=578 nm). Bovine Sermu Albumin-PE can be used to label or detect specific antigens, molecules or cellular structures .
Fura PE-3 potassium is a Ca 2+sensitive fluorophore. Fura PE-3 potassium loads in IPA (intrapulmonary arteries) and MA (mesenteric resistance arteries) for the research of vasoconstriction .
R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm).
NBD-PE is an effective lipid fluorescent probe (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology .
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines .
NP-PE (Phycoerythrin) is an immune complex. The formation and transport of NP-PE (Phycoerythrin) depends on the complement system, specifically through the complement receptors CR1 and CR2. These receptors are expressed on the surface of B cells and help B cells capture and transport immune complexes. NP-PE (Phycoerythrin) can be used to study the mechanisms by which B cells capture and transport immune complexes in lymph nodes .
C16-18:1 PE is a lipid. C16-18:1 PE has the activity of promoting membrane fusion and enhancing endosomal escape, which can significantly improve the delivery efficiency of mRNA. C16-18:1 PE is used in the synthesis of lipid nanoparticles (LNP) .
16:0 PDP PE belongs to a class of head group modified functionalized lipids. 16:0 PDP PE has been used in preparation of rhodamine high-density lipoprotein nanoparticle (Rh-HDL NP) synthesis.
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring choline phospholipid that can be synthesized from phosphatidylcholine and fatty acids. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is used as a structure-related lipid control .
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PE (PAPE), a compound isolated from egg yolk with antioxidant activity related to the unsaturated fatty acid content, was extracted, purified, and analyzed by various techniques.
18:1 PE AF 594 triammonium is a fluorescently labeled phospholipid probe. 18:1 PE AF 594 triammonium can be used as a fluorescent tracer for lipid nanoparticles (LNPs). 18:1 PE AF 594 triammonium is promising for research of drug delivery systems .
Preactivated PE-Cy5.5 Maleimide is a Preactivated PE-Cy5.5 Maleimide, which is a dye that can be used to label molecules such as dye that can be used to label molecules such as antibodies .
1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE (1-Palmitoyl-2-linoleoyl PE) is a lipid, which promotes nucleic acid such as sRNA to absorb and enter the target cell .
DMABA NHS ester can chemically react with the primary amine groups of the major phospholipid component of the cell membrane, Phosphatidylethanolamine (PE). Through precursor ion scanning, all PE subclasses labeled with DMABA can be detected. DMABA NHS ester can be used in combination with isotope-labeled compounds such as DMABA-d6 NHS ester, DMABA-d10 NHS ester, and DMABA-d4 NHS ester to observe changes in the distribution of PE lipids and the formation of novel PE lipid products .
16:0 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a phenyl maleimide group.
DNS-pE is a vinyl sulfone-based fluorescent probe that has the activity to selectively label 3-phosphoglycerate dehydrogenase (PHGDH) in living mammalian cells and generate fluorescence after labeling, while having inhibitory properties comparable to those of known inhibitors.
B-Phycoerythrin (B-PE) is a light-harvesting pigment protein that can be isolated from the red alga Porphyridium cruentum. The absorption spectrum of B-Phycoerythrin peaks at 545 nm and 563 nm, with a shoulder at 498 nm .
Mifamurtide (MTP-PE; CGP 19835) sodium hydrate is the sodium hydrate of mifamurtide. Mifamurtide is a nonspecific immunomodulator that acts by stimulating immune responses by activating macrophages and monocytes. Mifamurtide is a specific ligand for NOD2 and is used as an insulin sensitizer and may also be used in osteosarcoma research .
Mifamurtide sodium (MTP-PE sodium), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide sodium is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide sodium has potential for use in rare disease and osteosarcoma research .
Mifamurtide (MTP-PE), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide has potential for use in rare disease and osteosarcoma research .
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a derivative of phosphatidylethanolamine with lauric acid (12:0) acyl chains. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine can be used to synthesize liposomes .
Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium is used in the composition of lipid vesicles for supported lipid bilayer (SLB) formation. 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium can be used as a probe for understanding the interactions between proteins and lipid-tethered ligands .
Mifamurtide TFA (MTP-PE TFA), an analog of the muramyl dipeptide (MDP), is a nonspecific immunomodulator by stimulating the immune response activating macrophages and monocytes. Mifamurtide TFA is a specific ligand for NOD2 and acts as an insulin sensitizer. Mifamurtide TFA has potential for use in rare disease and osteosarcoma research .
18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:0 mPEG2000 PE ammonium can be used for drug delivery .
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE (15(S)-HETE-SAPE) is a phospholipid containing stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE (HY-113336) at the sn-2 position. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is formed by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LOX in human peripheral mononuclear cells activated with the calcium ionophore A23187 (HY-N6687).
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 (15(S)-HETE-SAPE-d11) is deuterium labeled 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (HY-N6687) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes .
DSPE-CH2-PEG-Fluor 488,MW 2000 is a PEG lipid conjugate with a DSPE group and a Fluor 488 dye. DSPE is a phosphoethanolamine (PE) lipid that can be used in the synthesis of liposomes. And Fluor 488 is a fluorescent dye .
18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-Pe (SAPE) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Pe (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine can be used for the research of premature ejaculation (PE) .
Dapoxetine (LY-210448) hydrochloride is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine hydrochloride can be used for the research of premature ejaculation (PE) .
Sulfo SMCC R-phycoerythrin is a conjugate composed of the protein crosslinker SMCC (HY-42360) and R-PE (R-Phycoerythrin) (HY-D0988) that can be used to label proteins to make them carry red fluorescence. Among them, SMCC is able to engage antigen-coupled spleen cells to induce antigen-specific immune responses .
DSPE-PEG-Fluor 555,MW 2000 is a PEG lipid conjugate with a DSPE group and a Fluor 555 dye. DSPE is a phosphoethanolamine (PE) lipid that can be used in the synthesis of liposomes. And Fluor 555 is a fluorescent dye .
18:1 Dimethyl PE (1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N,N-dimethyl) is a phospholipid that can be used as a biological material or organic compound for life science related research.
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance PP2A and PTP1B activities in malignant pleural mesothelioma cells. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis of NCI-H28 malignant pleural mesothelioma cells .
Dapoxetine (hydrochloride) (Standard) is the analytical standard of Dapoxetine (hydrochloride). This product is intended for research and analytical applications. Dapoxetine (LY-210448) hydrochloride is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine hydrochloride can be used for the research of premature ejaculation (PE) .
Dapoxetine (Standard) is the analytical standard of Dapoxetine. This product is intended for research and analytical applications. Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine can be used for the research of premature ejaculation (PE) .
1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls .
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
DMPE-PEG2000 (14:0 PEG2000 PE) is a surface functionalized material with improved lipid nanocarrier stability and ocular delivery efficiency compared to PEG2000. DMPE-PEG2000 is particularly suitable for the preparation of sterile ophthalmic formulations. In nanostructured lipid carriers (NLCs) of Ciprofloxacin (HY-B0356), DMPE-PEG2000 can significantly improve the drug's corneal penetration and ocular tissue distribution .
DPPE-PEG2000 ammonium (16:0 PEG2000 PE ammonium) is a PEG-modified lipids. DPPE-PEG2000 can reduce the nonspecific adsorption of protein and prolong circulation time in vivo. DPPE-PEG2000 can be used in liposome preparation. DPPE-PEG2000 is also used in preparation of tripeptide arginine-glycine-aspartic acid magnetoliposomes and poly(ethylene glycol) (PEG) – MLPs .
18:0 mPEG750 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG5000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG550 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG350 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG1000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
PREP Human Pre-designed siRNA Set A contains three designed siRNAs for PREP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
DMPE-PEG750 ammonium (14:0 PEG750 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG550 PE ammonium (DOPE-PEG550 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG350 ammonium (14:0 PEG350 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG1000 ammonium (14:0 PEG1000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG5000 PE ammonium (DOPE-PEG5000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG3000 PE ammonium (DOPE-PEG3000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG1000 PE ammonium (DOPE-PEG1000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG550 ammonium (14:0 PEG550 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG350 PE ammonium (DOPE-PEG350 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG5000 ammonium (14:0 PEG5000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG3000 ammonium (14:0 PEG3000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
Phosphorylethanolamine (Monoaminoethyl phosphate) is a membrane phospholipid and an important precursor of Phosphatidylcholine (HY-B2233B). It is found in most animal tissues and various human extracranial tumors, playing a critical role in membrane integrity, cell division, mitochondrial respiratory function, and more. Studies have shown that changes in the abundance of Phosphorylethanolamine are associated with Alzheimer's disease and Parkinson's disease. Lowering the ratio of Phosphorylethanolamine to Phosphatidylcholine in the liver can improve insulin signaling. Phosphorylethanolamine holds promise for research in the fields of cancer, neurodegenerative disorders, and metabolic diseases .
RFB4 is a anti-CD22 monoclonal antibody. RFB4 can construct recombinant immunotoxins by fusing with copper green pseudomonas exotoxin (PE38) through disulfide bonds such as RFB4(dsFv)-PE38. RFB4 can be used for research on cancer such as lymphoma .
2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternate might be via reduction in toxin content and breakdown of cell membrane integrity .
Protein A-RBITC is a biochemical reagent conjugated to fluorescein PE. Protein A-RBITC can be used to label or detect specific antigens, molecules or cellular structures .
Sulforhodamine 101 DHPE is a fluorescent probe made from the conjugation of the phospholipid 1,2-dipalmitoyl-sn-glycero-3-PE to sulforhodamine 101, a red fluorescent dye that displays excitation/emission spectra of 586/605 nm, respectively. It integrates into phospholipid bilayers and has been used for imaging of solid supported lipid bilayers, detection of protein-ligand binding on bilayers, and to monitor colocalization of lipid probes in liposomes via resonance energy transfer (RET).
Prep Mouse Pre-designed siRNA Set A contains three designed siRNAs for Prep gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Prolyl Endopeptidase Inhibitor 1 (Boc-Pro-prolinal) is a potent prolyl endopeptidase (PEP; PE) inhibitor, with a Ki value of 15 nM. Prolyl Endopeptidase Inhibitor 1 has anti-amnesic effect .
(Rac)-Dapoxetine hydrochloride is a racemate of Dapoxetine hydrochloride (HY-B0304A). Dapoxetine (LY-210448) hydrochloride is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine hydrochloride can be used for the research of premature ejaculation (PE) .
Dapoxetine-d6 is the deuterium labeled Dapoxetine . Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine can be used for the research of premature ejaculation (PE) .
LY 165163 is a potent 5-HT presynaptic receptor agonist. LY 165163 significantly decreases 5-HTP accumulation and increases DOPA accumulation in the cortex and striatum .
AP3B1 Human Pre-designed siRNA Set A contains three designed siRNAs for AP3B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Vari Fluor 555-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence when labeled, allowing for fluorescence imaging using the PE channel (Ex/Em=550 nm/561 nm) .
Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (HY-12031A) and PD 98059 (HY-12028) and the EGFR inhibitor AG-1478 (HY-13524).1 LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage.3 This product contains lysophosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position.
H-Pro-Glu-OH is a protein secreted by pathogenic mycobacteria through the Type VII secretion system. H-Pro-Glu-OH targets LipY lipases to the cell Surface via the ESX-5 Pathway .
1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a PE-based synthetic phospholipid that can intercalate with other amphiphilic molecules to form stable bilayers at physiological pH. 1-Palmitoyl-2-oleoylphosphatidylethanolamine can be used in drug delivery research .
DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
2-Phenylethyl isothiocyanate-d5 isothiocyanate-d5 is the deuterium labeled 2-Phenylethyl isothiocyanate[1]. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity[2][3].
1-Oleoyl-2-hydroxy-sn-glycero-3-PG (18:1 Lyso PE) sodium is a lysophospholipid containing oleic acid (18:1) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d70 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine. 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) is a phosphoethanolamine (PE) lipid that can be used in the synthesis
Anti-EGFR Antibody (D2C7) is a monoclonal antibody against EGFR. The recombinant immunotoxin D2C7-(scdsFv)-PE38KDEL constructed based on Anti-EGFR Antibody (D2C7) has antineoplastic activity in glioblastoma models .
DMPE-mPEG, MW 2000 is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.
(R)-HTS-3 is an lysophosphatidylcholine acyltransferase 3 (LPCAT3) inhibitor, with an IC50 of 0.09 μM. (R)-HTS-3 suppresses the C20:4 content of PE, PC, and PS, while promoting a correspondingelevation in C22:4 phospholipids and a paradoxical increase in C20:4 phosphatidylinositol (PI) lipids .
DOPE-CF is a pH-sensitive fluorescent membrane labelled probe with a fluorescein moiety that is a weak acid and a conjugated base that is highly fluorescent and can be attached to phospholipid ethanolamine lipids .
mPEG-DMPE (MW 1000) is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the?other?end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications .
1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (18:0 Lyso PE) sodium is a lysophospholipid containing stearic acid (18:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
FerroLOXIN-1 is a potent inhibitor of 15LOX-2 that selectively blocked production of pro-ferroptotic HOO-ETE-PE and protected against RSL3-induced ferroptosis. FerroLOXIN-1 closely interacted therein with 15LOX-2 only, and in particular with Y154, N155, W158 .
1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine has been used in the generation of liposomes and monolayers for use in the study of membrane permeability and monolayer viscosity, respectively.
BI-765063 is a humanized antibody expressed in CHO that targets SIRPa/CD172a. BI-765063 contains an IgG4PE type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 144.36 kDa. The isotype control for BI-765063 can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).
Ochnaflavone is an inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC50 of 3.45 µM. Ochnaflavone exhibits significant anti-inflammatory and liver-protective effects, capable of inhibiting the degradation of phosphatidylethanolamine (PE) and lipid peroxidation induced by carbon tetrachloride (CCl4) in rat liver, with an IC50 of 7.16 µM for lipid peroxidation. Ochnaflavone can be used in research on liver damage and inflammatory diseases .
N-Oleoyl-DPPE ammonium is an N-acylphosphatidylethanolamine (NAPE). N-Oleoyl-DPPE ammonium is a biosynthetic precursor of oleoylethanolamide (OEA), an endocannabinoid derivative and peroxisome proliferator-activated receptor α (PPARα) agonist. N-Oleoyl-DPPE ammonium can be used in the study of neuroinflammation and alcohol abuse .
N-Stearoyl-DPPE ammonium is a type of N-acylphosphatidylethanolamine (NAPE). N-Stearoyl-DPPE ammonium is an important intermediate in the endocannabinoid biosynthesis pathway .
DPPE-PEG350 is a CD1d-dependent lipid antagonist thus blocking the ERK phosphorylation pathway in iNKT cells . DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles.
DPPE-PEG550 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG750 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG3000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG1000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG5000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
Ethyl cinnamate (Standard) is the analytical standard of Ethyl cinnamate. This product is intended for research and analytical applications. Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
Ethyl cinnamate-d7 is deuterated labeled Ethyl cinnamate (HY-Y0121). Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
AChE/BChE-IN-27 is a blood-brain barrier–permeable mixed inhibitor (Pe = 4.12) of AChE and BChE, with IC50 values of 3.72 μM and 9.65 μM, respectively. AChE/BChE-IN-27 has potent antioxidant activity with an IC50 value of 6.32 μM in the DPPH (HY-112053) assay and also exhibits potent in vitro antioxidant activity. AChE/BChE-IN-27 exhibits metal chelating properties. AChE/BChE-IN-27 has neuroprotective potential against oxidative stress. AChE/BChE-IN-27 significantly reduces intracellular reactive oxygen species (ROS). In in vivo experiments, AChE/BChE-IN-27 effectively restored AChE and BChE levels, improved cognition, and can be used for Alzheimer's disease (AD) .
Fmoc-His(3-Me)OH derives Histidine-associating compounds with biological activity. Fmoc-His(3-Me)OH, with Fmoc-citrulline-OH, Fmoc-His(1-Me)-OH together, forms tri-peptides and shows vasodilating effect with EC50s of 2.7-4.7 mM in 1.0 mM Phenylephrine (PE)-contracted aorta rings. Fmoc-His(3-Me)OH (resin) also makes Methyl-His-Gly-Lys (His(3-Me)-Gly-Lys), thus acts as an [Ca 2+]i inhibitor. Fmoc-His(3-Me)OH methylates NAHIS02, making it unable to block the Alzheimer's Aβ channel .
PE154 (Compound 13) is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50s=280 pM and 16 nM, respectively) . PE154 can label β-amyloid plaques in histochemical analysis .
R-Phycoerythrin is found in Heterosiphonia japonica. R-Phycoerythrin is an orange-red fluorescent probe with α, β, and γ subunits. R-Phycoerythrin can be used in photodynamic therapy (PDT) to induce apoptosis in tumor cells. R-Phycoerythrin can be used in fluorescence microscopy, flow cytometry, and immunofluorescence analysis (Ex: 495 nm).
NBD-PE is an effective lipid fluorescent probe (Excitation/Emission: 465/535 nm; Color: Green). NBD-PE offers a wide array of applications in membrane and cell biology .
18:1 PE AF 594 triammonium is a fluorescently labeled phospholipid probe. 18:1 PE AF 594 triammonium can be used as a fluorescent tracer for lipid nanoparticles (LNPs). 18:1 PE AF 594 triammonium is promising for research of drug delivery systems .
PE-VF647 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. PE-VF647 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 665 nm.
PE-VF750 Maleimide is a thiol-reactive double-dye dye that contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/777 nm. PE-VF750 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 777 nm.
PE-VF680 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/701 nm. PE-VF680 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 701 nm.
Preactivated PE-Cy5.5 Maleimide is a Preactivated PE-Cy5.5 Maleimide, which is a dye that can be used to label molecules such as dye that can be used to label molecules such as antibodies .
B-Phycoerythrin (B-PE) is a light-harvesting pigment protein that can be isolated from the red alga Porphyridium cruentum. The absorption spectrum of B-Phycoerythrin peaks at 545 nm and 563 nm, with a shoulder at 498 nm .
Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
Sulfo SMCC R-phycoerythrin is a conjugate composed of the protein crosslinker SMCC (HY-42360) and R-PE (R-Phycoerythrin) (HY-D0988) that can be used to label proteins to make them carry red fluorescence. Among them, SMCC is able to engage antigen-coupled spleen cells to induce antigen-specific immune responses .
Vari Fluor 555-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence when labeled, allowing for fluorescence imaging using the PE channel (Ex/Em=550 nm/561 nm) .
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
DOPE-CF is a pH-sensitive fluorescent membrane labelled probe with a fluorescein moiety that is a weak acid and a conjugated base that is highly fluorescent and can be attached to phospholipid ethanolamine lipids .
18:0-18:2 PE is an important component of phosphatidylethanolamine (PE), involved in phospholipid metabolism and associated with diseases such as ovarian cancer. 18:0-18:2 PE in the hot processing process, its unsaturated fatty acids will degrade to form a variety of odor active compounds. 18:0-18:2 PE is mainly used in the field of food science to improve the flavor of aquatic products, as well as medical research on diseases related to phospholipid metabolism .
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines .
NP-PE (Phycoerythrin) is an immune complex. The formation and transport of NP-PE (Phycoerythrin) depends on the complement system, specifically through the complement receptors CR1 and CR2. These receptors are expressed on the surface of B cells and help B cells capture and transport immune complexes. NP-PE (Phycoerythrin) can be used to study the mechanisms by which B cells capture and transport immune complexes in lymph nodes .
Bovine Sermu Albumin-PE is a biochemical reagent conjugated to fluorescein PE (Ex=565 nm; Em=578 nm). Bovine Sermu Albumin-PE can be used to label or detect specific antigens, molecules or cellular structures .
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .
18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:0 mPEG2000 PE ammonium can be used for drug delivery .
18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
18:1 Dimethyl PE (1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N,N-dimethyl) is a phospholipid that can be used as a biological material or organic compound for life science related research.
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance PP2A and PTP1B activities in malignant pleural mesothelioma cells. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis of NCI-H28 malignant pleural mesothelioma cells .
DPPE-PEG2000 ammonium (16:0 PEG2000 PE ammonium) is a PEG-modified lipids. DPPE-PEG2000 can reduce the nonspecific adsorption of protein and prolong circulation time in vivo. DPPE-PEG2000 can be used in liposome preparation. DPPE-PEG2000 is also used in preparation of tripeptide arginine-glycine-aspartic acid magnetoliposomes and poly(ethylene glycol) (PEG) – MLPs .
18:0 mPEG750 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG5000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG550 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG350 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG1000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG750 ammonium (14:0 PEG750 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG550 PE ammonium (DOPE-PEG550 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG350 ammonium (14:0 PEG350 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG1000 ammonium (14:0 PEG1000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG5000 PE ammonium (DOPE-PEG5000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG3000 PE ammonium (DOPE-PEG3000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG1000 PE ammonium (DOPE-PEG1000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG550 ammonium (14:0 PEG550 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG350 PE ammonium (DOPE-PEG350 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG5000 ammonium (14:0 PEG5000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG3000 ammonium (14:0 PEG3000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
Protein A-RBITC is a biochemical reagent conjugated to fluorescein PE. Protein A-RBITC can be used to label or detect specific antigens, molecules or cellular structures .
1-Palmitoyl-2-oleoylphosphatidylethanolamine (POPE) is a PE-based synthetic phospholipid that can intercalate with other amphiphilic molecules to form stable bilayers at physiological pH. 1-Palmitoyl-2-oleoylphosphatidylethanolamine can be used in drug delivery research .
DOPE (GMP Like) is the GMP Like class DOPE (HY-112005), and can be used as pharmaceutical excipients. DOPE is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
mPEG-DMPE (MW 1000) is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the?other?end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications .
DPPE-PEG350 is a CD1d-dependent lipid antagonist thus blocking the ERK phosphorylation pathway in iNKT cells . DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles.
DPPE-PEG550 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG750 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG3000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG1000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG5000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
PE 22-28 is a TREK-1 inhibitor with IC50 value of 0.12 nM. PE 22-28 also is a 7 amino-acid peptide that is used as a core sequence for preparing analogs by chemical modifications and also by substitution of amino-acids. PE 22-28 can be used for the research of depression .
Fmoc-His(3-Me)OH derives Histidine-associating compounds with biological activity. Fmoc-His(3-Me)OH, with Fmoc-citrulline-OH, Fmoc-His(1-Me)-OH together, forms tri-peptides and shows vasodilating effect with EC50s of 2.7-4.7 mM in 1.0 mM Phenylephrine (PE)-contracted aorta rings. Fmoc-His(3-Me)OH (resin) also makes Methyl-His-Gly-Lys (His(3-Me)-Gly-Lys), thus acts as an [Ca 2+]i inhibitor. Fmoc-His(3-Me)OH methylates NAHIS02, making it unable to block the Alzheimer's Aβ channel .
(Pyr11)-Amyloid β-Protein (11-40) (A beta 11pE-40) is a peptide. (Pyr11)-Amyloid β-Protein (11-40) can be used for the research of Alzheimer's disease .
MCE Annexin V-PE Apoptosis Detection Kit provides a rapid and convenient method to detect cell apoptosis and necrosis. After staining, live cells show little or no fluorescence, apoptosis cells and necrosis cells show red fluorescence.
BI-765063 is a humanized antibody expressed in CHO that targets SIRPa/CD172a. BI-765063 contains an IgG4PE type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 144.36 kDa. The isotype control for BI-765063 can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).
PE0116 is a fully human CD137 agonistic monoclonal antibody generated from immunized harbor H2L2 human transgenic mice. PE0116 is a ligand block. PE0116 activates NF-κB signaling which significantly promotes T-cell proliferation and increases cytokine secretion in vitro. PE0116 exhibits robust antitumor activity in MC38 tumor model .
RFB4 is a anti-CD22 monoclonal antibody. RFB4 can construct recombinant immunotoxins by fusing with copper green pseudomonas exotoxin (PE38) through disulfide bonds such as RFB4(dsFv)-PE38. RFB4 can be used for research on cancer such as lymphoma .
Anti-EGFR Antibody (D2C7) is a monoclonal antibody against EGFR. The recombinant immunotoxin D2C7-(scdsFv)-PE38KDEL constructed based on Anti-EGFR Antibody (D2C7) has antineoplastic activity in glioblastoma models .
Phosphorylethanolamine (Monoaminoethyl phosphate) is a membrane phospholipid and an important precursor of Phosphatidylcholine (HY-B2233B). It is found in most animal tissues and various human extracranial tumors, playing a critical role in membrane integrity, cell division, mitochondrial respiratory function, and more. Studies have shown that changes in the abundance of Phosphorylethanolamine are associated with Alzheimer's disease and Parkinson's disease. Lowering the ratio of Phosphorylethanolamine to Phosphatidylcholine in the liver can improve insulin signaling. Phosphorylethanolamine holds promise for research in the fields of cancer, neurodegenerative disorders, and metabolic diseases .
Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
Ochnaflavone is an inhibitor of IIA-type secretory phospholipase A2 (sPLA2-IIA) with an IC50 of 3.45 µM. Ochnaflavone exhibits significant anti-inflammatory and liver-protective effects, capable of inhibiting the degradation of phosphatidylethanolamine (PE) and lipid peroxidation induced by carbon tetrachloride (CCl4) in rat liver, with an IC50 of 7.16 µM for lipid peroxidation. Ochnaflavone can be used in research on liver damage and inflammatory diseases .
Ethyl cinnamate (Standard) is the analytical standard of Ethyl cinnamate. This product is intended for research and analytical applications. Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein, as cells overexpressing mesothelin have altered adhesive properties. Mesothelin is also a Megakaryocyte-potentiating factor (MPF) which potentiates megakaryocyte colony formation in vitro. Mesothelin may be related to cancer metastasis. PE-Labeled Mesothelin Protein, Human (HEK293, His) is the recombinant human-derived PE-Labeled Mesothelin protein, expressed by HEK293 , with C-His, C-Avi labeled tag.
HLA-A*1101 is an important member of the MHC class I family and plays an important role in antigen presentation and immune surveillance. This complex is linked to the HLA-A*1101 allele and actively presents antigenic peptides to cytotoxic T lymphocytes, significantly promoting immune responses. PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGADGVGK, HEK293, His) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293. PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGADGVGK, HEK293), has molecular weight of 55-60 kDa.
HLA-A*1101 is an important member of the MHC class I family and plays an important role in antigen presentation and immune surveillance. This complex is linked to the HLA-A*1101 allele and actively presents antigenic peptides to cytotoxic T lymphocytes, significantly promoting immune responses. PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGAGGVGK, HEK293, His) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 . PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGAGGVGK, HEK293), has molecular weight of 55-60 kDa & 14 kDa, respectively.
The ACE2 protein is an important regulator of blood volume and cardiovascular homeostasis. PE-Labeled ACE2 Protein, Human (HEK293, His) is the recombinant human-derived PE-Labeled ACE2 protein, expressed by HEK293, with C-His labeled tag.
The SIRP α V4/CD172a protein is an immunoglobulin-like cell surface receptor for CD47 that acts as a docking protein to facilitate the translocation of PTPN6, PTPN11, and other partners to the plasma membrane. It supports the adhesion of cerebellar neurons, promotes neurite growth, and promotes glial cell attachment. PE-Labeled SIRP alpha/CD172a Protein, Human (HEK293, Fc) is the recombinant human-derived PE-Labeled SIRP alpha/CD172a protein, expressed by HEK293 , with Fc labeled tag.
IL-15R alpha Protein, a proven high-affinity receptor for interleukin-15, signals in both cis and trans. In neutrophils, it activates SYK kinase, crucial for IL-15-induced phagocytosis in a SYK-dependent manner. Different isoforms may introduce variations in signal transduction. Notably, IL-15R alpha Protein, while having high affinity, does not directly bind to IL15. PE-Labeled IL-15R alpha Protein, Human (HEK293, Fc) is the recombinant human-derived PE-Labeled IL-15R alpha protein, expressed by HEK293 , with Fc labeled tag.
The Glypican-3 (GPC3) protein is a cell surface proteoglycan that plays complex regulatory roles in key signaling pathways critical to developmental processes. Through its GPI anchoring, GPC3 negatively regulates the Hedgehog signaling pathway by competing with the Hedgehog receptor PTC1 for binding to Hedgehog protein, leading to complex internalization and subsequent lysosomal degradation. PE-labeled Glypican-3/GPC3 Protein, Human (HEK293, His) is the recombinant human-derived PE-labeled Glypican-3/GPC3 protein, expressed by HEK293 , with His labeled tag.
The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. PE-Labeled EGFR vIII Protein, Human (HEK293, His-Avi) is the recombinant human-derived EGFR vIII protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
HLA-G is a nonclassical major histocompatibility class Ib molecule that is critical for immune regulation at the maternal-fetal interface. It cooperates with B2M to form a complex that selectively binds self-peptides to promote maternal-fetal tolerance by interacting with KIR2DL4, LILRB1, and LILRB2 receptors. PE-Labeled HLA-G Complex Tetramer Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing HLA-G Protein and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with C-Avi, C-His labeled tag and RIIPRHLQL peptide. PE-Labeled HLA-G Complex Tetramer Protein, Human (HEK293, His-Avi), has molecular weight of 260-265 kDa.
The prolyl endopeptidase (PREP) protein is an enzyme capable of cleaving peptide bonds at the C-terminus of prolyl residues within peptides, particularly peptides up to about 30 amino acids in length.This enzymatic activity suggests a role for PREP in selective processing of peptides, particularly toward proline-containing substrates.Prolyl Endopeptidase/PREP Protein, Mouse (sf9, His) is the recombinant mouse-derived Prolyl Endopeptidase/PREP protein, expressed by Sf9 insect cells , with N-His labeled tag.
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 (15(S)-HETE-SAPE-d11) is deuterium labeled 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE. 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (HY-B2219) at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 (HY-N6687) by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE) by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes .
Dapoxetine-d6 is the deuterium labeled Dapoxetine . Dapoxetine (LY-210448) is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine can be used for the research of premature ejaculation (PE) .
2-Phenylethyl isothiocyanate-d5 isothiocyanate-d5 is the deuterium labeled 2-Phenylethyl isothiocyanate[1]. 2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternata might be via reduction in toxin content and breakdown of cell membrane integrity[2][3].
1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine-d70 is deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine. 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) is a phosphoethanolamine (PE) lipid that can be used in the synthesis
Ethyl cinnamate-d7 is deuterated labeled Ethyl cinnamate (HY-Y0121). Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga, exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC50 values of 0.30 mM and 0.38 mM in rat aorta .
Donkey Anti-Rabbit IgG H&L(PE) is a PE-conjugated and Donkey origined Polyclonal antibody, targeting to Goat IgG antibody. Donkey Anti-Rabbit IgG H&L(PE) can binds to the light and heavy chains of Rabbit IgG antibodies, thus can be used for IHC-F,IHC-P,ICC/IF,FC,ELISA assays in the background of Rabbit.
Armenian Hamster Anti-Mouse CD80 Antibody (PE) (YA3448) is a armenian hamster-derived and phycoerythrin (PE) IgG monoclonal antibody, targeting to CD80. It can be applicated for FC assays, in the background of mouse.
Rat Anti-Mouse F4/80 Antibody (PE)(YA3452) is a rat-derived and phycoerythrin (PE) IgG2b monoclonal antibody, targeting to F4/80. It can be applicated for FC assays, in the background of mouse.
Human CD73 Antibody (PE) (YA3515) is a mouse-derived and phycoerythrin (PE) IgG1 monoclonal antibody, targeting to CD73. It can be applicated for FC assays, in the background of human.
PTPRC; CD45; Receptor-tyPE tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45
FC
Human
Mouse Anti-Human CD45RA Antibody (PE/Cy7) is a non-conjugated and Mouse origined monoclonal antibody , targeting to CD45RA. It can be used for FC assays, in the background of Human.
Human CD138 Antibody (PE) (YA3444) is a mouse-derived and phycoerythrin (PE) IgG1 monoclonal antibody, targeting to CD138. It can be applicated for FC assays, in the background of human.
1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PE (18:0p/20:4-PE; C18(Plasm)-20:4-PE) is a plasmalogen that contains 1(Z)-octadecenoic acid and arachidonic acid (HY-109590) at the sn-1 and sn-2 positions, respectively.
C18(Plasm) LPE (PE(18:1p/0:0)) is a bioactive lipid with the activity of regulating cell signaling and promoting cell growth. C18(Plasm) LPE plays an important role in the composition of cell membranes and has a significant impact on lipid metabolism and cell function. C18(Plasm) LPE is also involved in lipid-mediated cellular responses and improves the adaptability of cells in various physiological and pathological conditions.
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines .
1-Palmitoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (1-Palmitoyl-2-Docosahexaenoyl-sn-glycero-3-PE; PE(16:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z))) is an ester product.
PES1 Human Pre-designed siRNA Set A contains three designed siRNAs for PES1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
PENK Human Pre-designed siRNA Set A contains three designed siRNAs for PENK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
1-Stearoyl-2-oleoyl-sn-glycerol-3-phosphoethanolamine is a phospholipids that contains stearic acid and oleic acid at the sn-1 and sn-2 positions, respectively. It has been used in the generation of lipid nanoparticles (LNPs) for in vitro delivery of mRNA or nuclear-targeted plasmid DNA.
16:0 PDP PE belongs to a class of head group modified functionalized lipids. 16:0 PDP PE has been used in preparation of rhodamine high-density lipoprotein nanoparticle (Rh-HDL NP) synthesis.
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring choline phospholipid that can be synthesized from phosphatidylcholine and fatty acids. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is used as a structure-related lipid control .
1-Palmitoyl-2-arachidonoyl-sn-glycero-3-PE (PAPE), a compound isolated from egg yolk with antioxidant activity related to the unsaturated fatty acid content, was extracted, purified, and analyzed by various techniques.
1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE (1-Palmitoyl-2-linoleoyl PE) is a lipid, which promotes nucleic acid such as sRNA to absorb and enter the target cell .
16:0 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a phenyl maleimide group.
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine (DLPE) is a derivative of phosphatidylethanolamine with lauric acid (12:0) acyl chains. 1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine can be used to synthesize liposomes .
18:0 mPEG2000 PE (DSPE-mPEG2000) ammonium is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:0 mPEG2000 PE ammonium can be used for drug delivery .
DSPE-CH2-PEG-Fluor 488,MW 2000 is a PEG lipid conjugate with a DSPE group and a Fluor 488 dye. DSPE is a phosphoethanolamine (PE) lipid that can be used in the synthesis of liposomes. And Fluor 488 is a fluorescent dye .
18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) is a polyethyleneglycol/phosphatidyl-ethanolamine conjugate. 18:1 PEG2000 PE ammonium (DOPE-PEG2000 ammonium) can be used for drug delivery .
18:0 mPEG2000 PE (DSPE-mPEG2000) sodium is a conjugate of phospholipid and polyethylene glycol, and it can serve as an important PEG lipid component in lipid nanoparticles (LNPs). 18:0 mPEG2000 PE sodium can be used in the research of gene transfection, drug carriers and drug delivery .
DSPE-PEG-Fluor 555,MW 2000 is a PEG lipid conjugate with a DSPE group and a Fluor 555 dye. DSPE is a phosphoethanolamine (PE) lipid that can be used in the synthesis of liposomes. And Fluor 555 is a fluorescent dye .
1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine (16:1 PE) is a phosphatidylethanolamine that can enhance PP2A and PTP1B activities in malignant pleural mesothelioma cells. 1,2-Dipalmitoleoyl-sn-glycero-3-phosphoethanolamine induces apoptosis of NCI-H28 malignant pleural mesothelioma cells .
1,3-Dipalmitoyl-glycero-2-phosphoethanolamine is a phospholipid containing the saturated long-chain (16:0) stearic acid inserted at the sn-1 and sn-3 positions and PE at the sn-2 site. It can be used in the generation of micelles, liposomes, and other types of artificial membranes.
1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls .
1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-phosphoethanolamine (18:0-22:6 PE) is a lipid compound that can be used for liposome preparation. Liposomes are the main component of vesicles with concentric phospholipid bilayer membranes, which can be used to construct drug delivery systems for anti-cancer and anti-infection fields. Highly polar water-soluble loads can be captured in the internal aqueous space of liposomes, while lipophilic loads can be distributed into the lipid bilayer and become part of the lipid bilayer. Especially for the delivery of antisense oligonucleotides, it can overcome the problems of inefficient cellular uptake and rapid loss in the body.
DMPE-PEG2000 (14:0 PEG2000 PE) is a surface functionalized material with improved lipid nanocarrier stability and ocular delivery efficiency compared to PEG2000. DMPE-PEG2000 is particularly suitable for the preparation of sterile ophthalmic formulations. In nanostructured lipid carriers (NLCs) of Ciprofloxacin (HY-B0356), DMPE-PEG2000 can significantly improve the drug's corneal penetration and ocular tissue distribution .
DPPE-PEG2000 ammonium (16:0 PEG2000 PE ammonium) is a PEG-modified lipids. DPPE-PEG2000 can reduce the nonspecific adsorption of protein and prolong circulation time in vivo. DPPE-PEG2000 can be used in liposome preparation. DPPE-PEG2000 is also used in preparation of tripeptide arginine-glycine-aspartic acid magnetoliposomes and poly(ethylene glycol) (PEG) – MLPs .
18:0 mPEG750 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG5000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG550 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG350 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG1000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:0 mPEG3000 PE (ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
PREP Human Pre-designed siRNA Set A contains three designed siRNAs for PREP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
DMPE-PEG750 ammonium (14:0 PEG750 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG550 PE ammonium (DOPE-PEG550 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG350 ammonium (14:0 PEG350 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG1000 ammonium (14:0 PEG1000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG5000 PE ammonium (DOPE-PEG5000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG3000 PE ammonium (DOPE-PEG3000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG1000 PE ammonium (DOPE-PEG1000 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG550 ammonium (14:0 PEG550 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymeric nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
18:1 PEG350 PE ammonium (DOPE-PEG350 ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG5000 ammonium (14:0 PEG5000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DMPE-PEG3000 ammonium (14:0 PEG3000 PE ammonium) is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
Prep Mouse Pre-designed siRNA Set A contains three designed siRNAs for Prep gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
AP3B1 Human Pre-designed siRNA Set A contains three designed siRNAs for AP3B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
1-Oleoyl-2-hydroxy-sn-glycero-3-PG (18:1 Lyso PE) sodium is a lysophospholipid containing oleic acid (18:1) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
DOPE (Dioleoylphosphatidylethanolamine) is a neutral helper lipid for cationic liposome and combines with cationic phospholipids to improve transfection efficiency of naked siRNA .
DMPE-mPEG, MW 2000 is a PEGylated 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine (14:0 PE) compound with a methyl group at the other end of the PEG chain. The PEG polymer exhibits amphiphatic behavior and helps to form stable micelles in an aqueous solution. It can be used to prepare nanoparticles or liposomes for targeted drug delivery applications.
1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (18:0 Lyso PE) sodium is a lysophospholipid containing stearic acid (18:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems.
1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine has been used in the generation of liposomes and monolayers for use in the study of membrane permeability and monolayer viscosity, respectively.
DPPE-PEG350 is a CD1d-dependent lipid antagonist thus blocking the ERK phosphorylation pathway in iNKT cells . DPPE-PEG350 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles.
DPPE-PEG550 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG750 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG3000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG1000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
DPPE-PEG5000 is a PEG lipid functional end group used in the synthesis of liposomes (LPs) for the design of conjugated polymer nanoparticles. Through biotin modification and carboxyl terminus, lipid nanoparticles (LNPs) further coupling with other biomolecules can be achieved. Functionalized nanoparticles can be used for targeted labeling of specific cellular proteins. With streptavidin as a linker, biotinylated PEG lipid-conjugated polymer nanoparticles are able to bind to biotinylated antibodies on cell surface receptors, yielding the utility of fluorescence-based imaging and sensing.
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