Search Result
Results for "
Lucidum
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-159059
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- HY-125361
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Others
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Others
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Ganosporeric acid A, a natural product, is isolated from the ether-soluble fraction of the spores of Ganoderma lucidum. Ganosporeric acid A can be used for the research of liver injury .
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- HY-N10070
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Others
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Others
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Lucidumol A is a Triterpenoids product that can be isolated from the fruit body of Ganoderma lucidum .
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-
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- HY-107259
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23S-Hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic
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Others
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Others
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23S-Hydroxyl-11,15-dioxo-ganoderic acid DM is a compound isolated from the fruit bodies of Ganoderma lucidum .
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-
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- HY-N3844
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Others
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Others
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Ergosta-7,22-dien-3-on is a lanosterane isolated from the fruiting bodies of Ganoderma lucidum. ent-16-Kaurene-3b,15b,18-triol inhibits platelet aggregation .
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- HY-N8819
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NO Synthase
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Others
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Methyl ganoderate H is a natural product that can be isolated from Ganoderma lucidum. Methyl ganoderate H has moderate inhibitory effect to NO production .
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- HY-N11640
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Others
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Neurological Disease
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Methyl Ganoderic acid B is a triterpenoid, that can be isolated from Ganoderma lucidum. Methyl Ganoderic acid B has nerve growth factor-like neuronal survival-promoting effects .
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-
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- HY-N11636
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Apoptosis
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Cancer
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Ganoderic acid S is a positional isomer of ganoderic acids, that can be isolated from the fermented mycelia of Ganoderma lucidum. Ganoderic acid S can induce apoptosis in HeLa cells through the mitochondria pathway .
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-
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- HY-N11641
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Cholinesterase (ChE)
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Neurological Disease
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Methyl ganoderate A acetonide, a lanostane triterpene, is a natural product that could be isolated from the fruiting bodies of Ganoderma lucidum. Methyl ganoderate A acetonide is a potent AChE inhibitor with an IC50 value of 18.35 μM. Methyl ganoderate A acetonide can be used in research of Alzheimer’s disease (AD) .
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- HY-N11643
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GA-Mk
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Apoptosis
Reactive Oxygen Species
MMP
Caspase
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Cancer
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Ganoderic acid Mk (GA-Mk) is a triterpenoid acid, that can be isolated from the mycelia of Ganoderma lucidum. Ganoderic acid Mk is efficiently anti-proliferative and can induce apoptosis of HeLa cells by mitochondria-mediated pathway. Ganoderic acid Mk can be used for cervical cancer research .
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- HY-125443
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Others
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Cancer
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Lucialdehydes A is a lanostante-type triterpene aldehydes, isolated from the fruiting bodies of Ganoderma lucidum. Lucialdehydes A shows cytotoxic effects on tumor cells, including Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines .
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- HY-N8106
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Others
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Cancer
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7,15-Dihydroxy-4,4,14-trimethyl-3,11-dioxochol-8-en-24-oic acid is one of the ganoderma triterpenoids which have been recognised as an important bioactive ingredient in Ganoderma Lucidum Karst. 7,15-Dihydroxy-4,4,14-trimethyl-3,11-dioxochol-8-en-24-oic acid can be used for the research of various etiologies .
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- HY-107265
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- HY-N2999
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Others
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Others
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Ganoderic acid I is a triterpenoid found in ganoderma lucidum .
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-
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- HY-N1512
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Others
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Others
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Ganoderic acid E is a triterpenoid found in Ganoderma lucidum .
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-
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- HY-129154
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Others
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Others
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Ganolucidic acid A is a natural product that can be isolated from Ganoderma lucidum .
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- HY-N6859
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- HY-N11591
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Others
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Others
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Ganoderic acid T is a natural product that can be found in ganoderma lucidum .
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- HY-N3372
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Others
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Others
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Longifloroside A is a Lignans product that can be isolated from the seeds of Ligustrum lucidum .
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- HY-N7021
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-
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- HY-N2221
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- HY-129153
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Others
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Others
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Ganoderic acid ζ is a triterpene that can be isolated from the spores of Ganoderma lucidum .
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-
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- HY-N3501
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-
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- HY-N8602
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Others
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Others
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Ganoderenic acid F (compound 17) is a triterpenoid that can be found in ganoderma lucidum .
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-
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- HY-129160
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Others
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Others
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Ganoderenic acid H is a compound isolated from the fruit bodies of Ganoderma lucidum .
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- HY-N6874
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Others
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Others
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Ligustrosidic acid is a natural compound isolated from ligustrum japonicum and ligustrum lucidum .
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- HY-N2223
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Ganodermadiol
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Glycosidase
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Metabolic Disease
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Ganoderol B is a potent α-glucosidase inhibitor. Ganoderol B has high α-glucosidase inhibition with an IC50 of 48.5 μg/mL (119.8 μM) .
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- HY-123100
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Others
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Others
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Ganoderic acid N is a natural terpenoid isolated from the Fungus Ganoderma lucidum .
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- HY-N2458
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Others
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Infection
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Ganoderic acid G is a triterpene isolated from the surface part of gills of Ganoderma lucidum .
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- HY-N9853
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Others
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Others
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Methyl lucidenate A is a Triterpenoids product that can be isolated from the fruit body of Ganoderma lucidum .
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- HY-N5153
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Others
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Others
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12β-Acetoxyganoderic Acid θ is a triterpenoid that can be isolated from G. lucidum .
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- HY-N3923
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Others
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Others
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Ganoderic acid S1 (compound 4) is a natural product that can be found in ganoderma lucidum .
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- HY-N1164
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(-)-Tetrachyrin; Zoapatlin
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Others
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Others
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Tetrachyrin ((-)-Tetrachyrin) is a Triterpenoids product that can be isolated from the fruit body of Ganoderma lucidum .
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-
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- HY-N2724
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Others
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Others
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6-O-Methylcerevisterol is a Steroids product that can be isolated from the fungus Ganoderma lucidum .
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- HY-N1790
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Others
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Others
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6-Dehydrocerevisterol is a Steroids product that can be isolated from the fruit body of Ganoderma lucidum .
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- HY-N9843
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Others
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Others
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Methyl ganoderenate D is a Triterpenoids product that can be isolated from the fruit body of Ganoderma lucidum .
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- HY-N9829
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Others
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Others
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Methyl lucidenate E2 is a Triterpenoids product that can be isolated from the fruit body of Ganoderma lucidum .
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- HY-N6055
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Influenza Virus
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Infection
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Nuezhenidic acid can be isolated from the fruits of Ligustrum lucidum, posseses inhibitory activities against influenza A virus .
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- HY-113898
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- HY-N9312
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Others
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Inflammation/Immunology
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Ganoderic acid J is a natural terpenoid isolated from the Fungus Ganoderma lucidum. Ganoderic acid J possesses anti-inflammatory anti-inflammatory activity .
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- HY-N2997
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Others
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Cancer
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Ganoderic acid LM2 is a natural terpenoid isolated from the Fungus Ganoderma lucidum. Ganoderic acid LM2 possesses potential anti-tumor activity .
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- HY-N9350
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Others
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Cancer
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Ganoderic acid ε is a natural terpenoid isolated from the Fungus Ganoderma lucidum. Ganoderic acid ε exhibits an ED50 of 12.2 μg/mL in Meth-A tumor cells
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- HY-N3500
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- HY-N6862
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MMP
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Cancer
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Lucideric acid A is a natural compound isolated from Ganoderma lucidum, inhibits PMA-induced MMP-9 activity, with anti-invasive effect on hepatoma cells .
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- HY-N6860
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MMP
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Cancer
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Lucidenic acid C is a natural compound isolated from Ganoderma lucidum, inhibits PMA-induced MMP-9 activity, with anti-invasive effect on hepatoma cells .
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- HY-N8039
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Ganodermic acid T-Q
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Microtubule/Tubulin
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Cancer
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Ganoderic acid T-Q (Ganodermic acid T-Q) (compound 1) is a natural product that can be found in ganoderma lucidum. Ganoderic acid T-Q stimulates tubulin polymerization .
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- HY-129151
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TNF Receptor
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Inflammation/Immunology
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Ganoderic acid C1, a natural compound that could be isolated from G. lucidum, suppresses TNF-α production by murine macrophages (RAW 264.7 cells) .
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- HY-N1516
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Apoptosis
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Cancer
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Ganoderenic acid D is a triterpene identified from the effective compounds of Ganoderma lucidum extract (GLE). Ganoderenic acid D inhibits the proliferation of cancer cells by inducing cell cycle arrest and apoptosis .
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- HY-N11639
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Aldose Reductase
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Metabolic Disease
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Ganoderic acid Df is a lanostane-type triterpenoid, that can be isolated from the fruiting body of Ganoderma lucidum. Ganoderic acid Df potently inhibits aldose reductase, with an IC50 of 22.8 ± 0.6 μM .
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- HY-129148
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GAAM1
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Others
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Cancer
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Ganoderic acid AM1 (GAAM1) is a natural product that can be found in ganoderma lucidum. Ganoderic acid AM1 shows cytotoxicity with an IC50 value of 19.8 µM for HeLa cells .
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- HY-N3925
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Bacterial
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Infection
Metabolic Disease
Inflammation/Immunology
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Ganoderol A is a terpenoid extracted from Ganoderma lucidum with antimicrobial activities. Ganoderol A inhibits cholesterol synthesis pathway and has significant anti-inflammatory activity and protection against ultraviolet A (UVA) damage .
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- HY-N11637
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HMG-CoA Reductase (HMGCR)
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Inflammation/Immunology
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Ganoderenic acid K is a natural product, that can be isolated from fruiting bodies of Ganoderma lucidum. Ganoderenic acid K shows strong inhibitory activity against HMG-CoA reductase (HMGCR) with IC50 of 16.5 μM .
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- HY-N2721
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6'-O-trans-cinnamoyl 8-epikingisidic acid
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Others
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Others
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6'-O-Cinnamoyl-8-epikingisidic acid (6'-O-trans-cinnamoyl 8-epikingisidic acid) is a secoiridoid constituent isolated from the dried fruits of Ligustrum lucidum AIT .
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- HY-N15224
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Endogenous Metabolite
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Others
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15-Hydroxy-3,11,23-trioxolanost-8,20-dien-26-oic acid (comound 35) is a triterpenoid that can be isolated from Ganoderma lucidum .
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- HY-120140
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- HY-N15225
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Others
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Others
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12β-Hydroxyganoderenic acid B (Compound 15) is the triterpenoid compound that can be isolated from Ganoderma lucidum. Some triterpenoids isolated from Ganoderma species are reported to exhibits antitumor, antimicrobial, antiviral and anti-aging activities .
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- HY-N7346
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HSV
Cholinesterase (ChE)
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Infection
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Lucidadiol is a natural compound isolated from Ganoderma lucidum. Lucidadiol exhibits acetylcholinesterase-inhibitory activity, with IC50 values of 31 μM. Lucidadiol shows antiviral activity against influenza virus type A and HSV type 1 .
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- HY-N11637A
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HMG-CoA Reductase (HMGCR)
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Inflammation/Immunology
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(Z)-Ganoderenic acid K is a triterpene acid that can be isolated from the basidiocarp of Ganoderma lucidum. Ganoderenic acid K (HY-N11637), the isomer of (Z)-Ganoderenic acid K, is a HMG-CoA reductase (HMGCR) inhibitor with an IC50 of 16.5 μM .
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- HY-N1506
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Epigenetic Reader Domain
p38 MAPK
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Cancer
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Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity .
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- HY-N1513
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AP-1
NF-κB
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Cancer
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Ganoderic acid H is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderic acid H suppresses growth and invasive behavior of breast cancer cells through the inhibition of transcription factors AP-1 and NF-kappaB signaling .
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- HY-N1514
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P-glycoprotein
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Cancer
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Ganoderenic acid B is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderenic acid B exhibits potent reversal effect on ABCB1-mediated multidrug resistance of HepG2/ADM cells to Doxorubicin .
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- HY-N13705
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Others
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Others
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3β,7β-Dihydroxy-11,15,23-trioxo-lanost-8,16-dien-26-oic acid is a triterpene compound that can be found in Ganoderma lucidum .
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- HY-N1517
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Aldose Reductase
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Inflammation/Immunology
Cancer
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Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 is the inhibitor for aldose reductase with an IC50 of 43.8 µM .
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- HY-N6861
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Apoptosis
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Cancer
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Lucidenic acid B is a natural compound isolated from Ganoderma lucidum, induces apoptosis of cancer cells, and causes the activation of caspase-9 and caspase-3, and cleavage of PARP. Lucidenic acid B does not affect the cell cycle profile, or the number of necrotic cells .
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- HY-N2277
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- HY-125664
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Antibiotic
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Cancer
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Lucialdehyde B is a tetracyclic triterpene isolated from the substrates of Ganoderma lucidum with antiviral and cytotoxic activities. Lucialdehyde B has cytotoxic effects against Lewis lung cancer (LLC), T-47D, Sarcoma 180 and Meth-A tumor cell lines .
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- HY-N2006
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EBV
HIV Protease
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Infection
Inflammation/Immunology
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Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM) .
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- HY-118736
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Others
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Cardiovascular Disease
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Ganodermic acid S is an oxygenated triterpenoid, that can be isolated from the Chinese medicinal fungus Ganoderma lucidum (Fr.) Karst (Polyporaceae). Ganodermic acid S exerts a concentration dependent inhibition on the response of human gel-filtered platelets (GFP) to U-46619 (HY-108566), a thromboxane (TX) A2 mimetic .
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- HY-N1517R
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Aldose Reductase
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Inflammation/Immunology
Cancer
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Ganoderic acid C2 (Standard) is the analytical standard of Ganoderic acid C2. This product is intended for research and analytical applications. Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 is the inhibitor for aldose reductase with an IC50 of 43.8 µM .
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- HY-N1517A
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Aldose Reductase
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Cancer
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(Rac)-Ganoderic acid C2 is the racemate of Ganoderic acid C2 (HY-N1517). Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses anti-tumor, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM[ .
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- HY-N2006R
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EBV
HIV Protease
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Infection
Inflammation/Immunology
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Ganoderic acid B (Standard) is the analytical standard of Ganoderic acid B. This product is intended for research and analytical applications. Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM) .
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- HY-N0665
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(8E)-Nuezhenide
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NF-κB
Wnt
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Inflammation/Immunology
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Specnuezhenide ((8E)-Nuezhenide) is isolated from the fruits of?Ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) can inhibit IL-1β-induced inflammation in chondrocytes via inhibition of NF-κB and wnt/β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide) exerts anti-inflammatory effects in a rat model of osteoarthritis (OA) .
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- HY-N2996
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HIV Protease
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Infection
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Ganodermanondiol is a melanogenesis inhibitor isolated from the Ganoderma lucidum .Ganodermanondiol exhibits potent cytoprotective effects on tert-butyl hydroperoxide-induced hepatotoxicity . Ganodermanondiol shows significant anti-HIV-1 protease activity with an IC50 of 90 μM . Ganodermanondiol exhibits a strong anticomplement activity against the classical pathway of the complement system with an IC50 of 41.7μM .
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- HY-146329R
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Bacterial
Antibiotic
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Infection
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Ganoderic acid C2 (Standard) is the analytical standard of Ganoderic acid C2. This product is intended for research and analytical applications. Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM .
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- HY-N1511
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Sirtuin
Apoptosis
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Cancer
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Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
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- HY-N0665R
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NF-κB
Wnt
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Inflammation/Immunology
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Specnuezhenide (Standard) is the analytical standard of Specnuezhenide. This product is intended for research and analytical applications. Specnuezhenide ((8E)-Nuezhenide) is isolated from the fruits of?Ligustrum lucidum. Specnuezhenide ((8E)-Nuezhenide) can inhibit IL-1β-induced inflammation in chondrocytes via inhibition of NF-κB and wnt/β-catenin signaling. Specnuezhenide ((8E)-Nuezhenide) exerts anti-inflammatory effects in a rat model of osteoarthritis (OA) .
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- HY-N13701
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NO Synthase
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Inflammation/Immunology
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3β,7β,15α-Trihydroxy-4-(hydroxymethyl)-11,23-dioxo-lanost-8-en-26-oic acid is a triterpene compound that can be found in Ganoderma lucidum, and it inhibits nitric oxide (NO) production in BV-2 microglial cells induced by lipopolysaccharide (LPS, HY-D1056), with an IC50 of 4.15 μM .
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- HY-N13739
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Tyrosinase
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Cancer
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Taraxinic acid can be found in the roots of Taraxacum flavostylum and Taraxacum lucidum. It is a Tyrosinase inhibitor that dose-dependently inhibits Tyrosinase activity, showing approximately 54.5% inhibition at a concentration of 50 μg/mL. Taraxinic acid has an IC50 of 83.2 μM against melanoma cells A375 and HTB140, and an IC50 of 60.4 μM against melanoma cells WM793, with activity being both dose- and time-dependent. Taraxinic acid holds promise for research in the field of anticancer therapy .
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- HY-N13706
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NO Synthase
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Inflammation/Immunology
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3β,15α-Dihydroxy-7,11,23-trioxo-lanost-8-dien-26-oic acid is a triterpene compound that can be found in Ganoderma lucidum, and it inhibits nitric oxide (NO) production in BV-2 microglial cells induced by lipopolysaccharide (LPS, HY-D1056), with an IC50 of 6.50 μM, making it a potential candidate for anti-inflammatory research .
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- HY-N0546
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Nuezhenoside
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CaSR
RIP kinase
Mixed Lineage Kinase
TGF-beta/Smad
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
Endocrinology
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Ligustroflavone is an orally active flavonoid compound. Ligustroflavone can be extracted from Ligustrum lucidum. Ligustroflavone antagonizes the calcium-sensing receptor (CaSR), inhibits the RIPK1/RIPK3/MLKL pathway, and downregulates TGF-β/Smad signaling. Ligustroflavone regulates calcium metabolism, protects bone tissue, reduces cerebral ischemic injury, and inhibits liver fibrosis. Ligustroflavone can be used in the study of diabetic osteoporosis, ischemic stroke, and liver fibrosis .
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- HY-N1511R
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Sirtuin
Apoptosis
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Cancer
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Ganoderic acid D (Standard) is the analytical standard of Ganoderic acid D. This product is intended for research and analytical applications. Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
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- HY-N0546R
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Nuezhenoside (Standard)
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Reference Standards
CaSR
RIP kinase
Mixed Lineage Kinase
TGF-beta/Smad
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Cardiovascular Disease
Neurological Disease
Metabolic Disease
Endocrinology
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Ligustroflavone (Standard) is the analytical standard of Ligustroflavone (HY-N0546). This product is intended for research and analytical applications. Ligustroflavone is an orally active flavonoid compound. Ligustroflavone can be extracted from Ligustrum lucidum. Ligustroflavone antagonizes the calcium-sensing receptor (CaSR), inhibits the RIPK1/RIPK3/MLKL pathway, and downregulates TGF-β/Smad signaling. Ligustroflavone regulates calcium metabolism, protects bone tissue, reduces cerebral ischemic injury, and inhibits liver fibrosis. Ligustroflavone can be used in the study of diabetic osteoporosis, ischemic stroke, and liver fibrosis .
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- HY-N8229
-
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Others
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Inflammation/Immunology
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7β,15α,20-Trihydroxy-3,11,23-trioxo-5α-lanosta-8-en-26-oic acid is a triterpenoid compound found in Ganoderma lucidum. 7β,15α,20-Trihydroxy-3,11,23-trioxo-5α-lanosta-8-en-26-oic acid may exhibit anti-inflammatory activity and holds potential for research in inflammatory diseases .
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- HY-N13710
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EBV
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Infection
Cancer
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20-Hydroxylucidenic acid E2 is a triterpenoid compound found in Ganoderma lucidum. It exhibits significant inhibitory effects on inflammation induced by TPA (HY-18739). Additionally, 20-Hydroxylucidenic acid E2 can suppress the expression of EBV early antigen induced by TPA (HY-18739), with a IC50 of 290 mol ratio/32 pmol TPA (meaning that when the molar concentration of this compound is 290 times that of 32 pmol of TPA, it can inhibit 50% of EBV early antigen expression). Therefore, 20-Hydroxylucidenic acid E2 has potential applications in anti-inflammatory and anticancer research .
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Cat. No. |
Product Name |
Type |
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
- HY-120140
-
-
- HY-N15225
-
-
- HY-N7346
-
-
- HY-N11637A
-
-
- HY-N1506
-
-
- HY-N1513
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-
- HY-N1514
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-
- HY-N13705
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-
- HY-N1517
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-
- HY-N6861
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-
- HY-N2277
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-
- HY-125664
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-
- HY-N2006
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-
- HY-118736
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-
- HY-N1517R
-
-
- HY-N1517A
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- HY-N2006R
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- HY-N0665
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- HY-N2996
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- HY-N1511
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- HY-N0665R
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- HY-N13701
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- HY-N13739
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Structural Classification
Terpenoids
Sesquiterpenes
Source classification
Asteraceae
Taraxacum coreanum Nakai
Plants
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Tyrosinase
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Taraxinic acid can be found in the roots of Taraxacum flavostylum and Taraxacum lucidum. It is a Tyrosinase inhibitor that dose-dependently inhibits Tyrosinase activity, showing approximately 54.5% inhibition at a concentration of 50 μg/mL. Taraxinic acid has an IC50 of 83.2 μM against melanoma cells A375 and HTB140, and an IC50 of 60.4 μM against melanoma cells WM793, with activity being both dose- and time-dependent. Taraxinic acid holds promise for research in the field of anticancer therapy .
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- HY-N13706
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- HY-N0546
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- HY-N1511R
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Triterpenes
Structural Classification
Terpenoids
Polyporaceae
Ganoderma lucidum (Leyss. Ex Fr.) Karst.
Plants
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Sirtuin
Apoptosis
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Ganoderic acid D (Standard) is the analytical standard of Ganoderic acid D. This product is intended for research and analytical applications. Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
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- HY-N0546R
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- HY-N8229
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- HY-N13710
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Triterpenes
Structural Classification
Microorganisms
Terpenoids
Source classification
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EBV
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20-Hydroxylucidenic acid E2 is a triterpenoid compound found in Ganoderma lucidum. It exhibits significant inhibitory effects on inflammation induced by TPA (HY-18739). Additionally, 20-Hydroxylucidenic acid E2 can suppress the expression of EBV early antigen induced by TPA (HY-18739), with a IC50 of 290 mol ratio/32 pmol TPA (meaning that when the molar concentration of this compound is 290 times that of 32 pmol of TPA, it can inhibit 50% of EBV early antigen expression). Therefore, 20-Hydroxylucidenic acid E2 has potential applications in anti-inflammatory and anticancer research .
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