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Results for "

IL-6R

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

1

Peptides

8

Inhibitory Antibodies

21

Recombinant Proteins

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P990211

    Interleukin Related Inflammation/Immunology Cancer
    Anti-Mouse IL-6R Antibody (15A7) is a rat-derived anti-mouse IL-6R IgG2b κ type antibody inhibitor. Anti-Mouse IL-6R Antibody (15A7) blocks IL-6 binding to IL-6Rα and inhibits both IL-6 classic and trans-signaling. Anti-Mouse IL-6R Antibody (15A7) can be used for the researches of cancer and inflammation, such as triple-negative breast cancer .
    Anti-Mouse IL-6R Antibody (15A7)
  • HY-P9917
    Tocilizumab
    35+ Cited Publications

    Anti-Human IL6R, Humanized Antibody

    Interleukin Related Inflammation/Immunology Cancer
    Tocilizumab (Anti-Human IL6R, Humanized Antibody) is an anti-human interleukin-6 receptor (IL-6R) neutralizing antibody, prevents binding of IL-6 to the IL-6R, thereby inhibiting both classic and trans-signaling. Tocilizumab (Anti-Human IL6R, Humanized Antibody) can be used for the treatment of rheumatoid arthritis . Tocilizumab is remarkablely effective for the study of severe COVID-19 (coronavirus disease) .
    Tocilizumab
  • HY-P10284

    Interleukin Related Cancer
    S7 is an IL-6 receptor antagonist and inhibits the binding between IL-6 and IL-6R. S7 can inhibit angiogenesis and tumor growth .
    S7
  • HY-P99702

    BCD-089

    Interleukin Related Inflammation/Immunology
    Levilimab (BCD-089) is a fully humanized anti-interleukin-6 receptor (IL-6R) monoclonal antibody. Levilimab is an inflammation-alleviating antibody. Levilimab can be used for the research of rheumatoid .
    Levilimab
  • HY-P99112

    RG-6168; SA-237

    Interleukin Related Inflammation/Immunology Cancer
    Satralizumab is a humanized monoclonal antibody that targets IL-6R. Satralizumab prevents dTAA formation and progression in rattus norvegicus. Satralizumab can be used for neuromyelitis optica spectrum disorder (NMOSD) and descending thoracic aorta aneurysm (dTAA) research .
    Satralizumab
  • HY-P9916

    Anti-Human IL6Rα, Human Antibody

    Interleukin Related Inflammation/Immunology Cancer
    Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis .
    Sarilumab
  • HY-RS06777

    Small Interfering RNA (siRNA) Others

    IL6R Human Pre-designed siRNA Set A contains three designed siRNAs for IL6R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    IL6R Human Pre-designed siRNA Set A
    IL6R Human Pre-designed siRNA Set A
  • HY-RS23587

    Small Interfering RNA (siRNA) Others

    Il6r Rat Pre-designed siRNA Set A contains three designed siRNAs for Il6r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Il6r Rat Pre-designed siRNA Set A
    Il6r Rat Pre-designed siRNA Set A
  • HY-174599

    mRNA Inflammation/Immunology
    Human IL6R mRNA encodes the human interleukin 6 receptor (IL6R) protein, a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response.
    Human IL6R mRNA
  • HY-P991602

    TZLS-501

    Interleukin Related Cancer
    NI-1201 is a monoclonal antibody that targets, in the human IL-6R sequence, the epitope recognized by 25F10 for mice. NI-1201 inhibits both IL-6 cis- and trans-signaling. NI-1201 targets site IIb of hIL-6R. NI-1201 inhibits gp130 binding to IL-6R .
    NI-1201
  • HY-P99385

    ALX-0061

    Interleukin Related Inflammation/Immunology
    Vobarilizumab (ALX-0061) is a humanized bispecific anti-IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) (Kd: 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis .
    Vobarilizumab
  • HY-P991519

    Interleukin Related Inflammation/Immunology
    VDJ001 is a high-affinity humanized anti-IL-6R monoclonal antibody. VDJ001 can be used for the study of rheumatoid arthritis .
    VDJ001
  • HY-177063

    Interleukin Related Others
    IL-6-IN-2 (Compound 15) is an inhibitor of the IL-6/IL-6R protein interaction. The ∆G binding energy of IL-6-IN-2 is −36.50 kcal/mol. Contributions of Lys66, Phe74, Gln175, Ser176, and Arg179 to IL-6 binding are −1.10, −8.68, −6.91, −3.69, and −1.72 kcal/mol, respectively. IL-6-IN-2 exhibits low gastrointestinal (GI) absorption .
    IL-6-IN-2

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