Search Result
        
        
            
                Results for "
Gram-positive bacteria infections
" in MedChemExpress (MCE) Product Catalog:
            
         
        
        
            
                
            
            
            
            
                
                    2
Biochemical Assay Reagents
 
            
            
                
            
            
            
            
                
            
            
            
                
                    18
Isotope-Labeled Compounds
 
            
            
            
            
         
        
            
            
                
                    
                    
                        
                            | Cat. No. | Product Name | Target | Research Areas | Chemical Structure | 
                    
                    
                        
                            
                            - 
                                
                                    - HY-117660
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                                                | U-10149 | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Lincomycin, a lincosamide antibiotic, is an antimicrobial agent used for the research of Gram-positive bacteria infections . |  
 
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                                    - HY-B2237A
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                                                |  | Bacterial
                                                    
                                                        HIV | Infection |  
                                                | Lysozyme chloride is a bactericidal enzyme, and it lyses gram-positive bacteria. Lysozyme chloride can also be used for the research of HIV infection and pulmonary emphysema   . |  
 
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                                    - HY-B1466
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                                                | BAY-f 1353 sodium | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research  . |  
 
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                                    - HY-B2237
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                                                |  | Bacterial
                                                    
                                                        HIV | Infection |  
                                                | Lysozyme from chicken egg white is a bactericidal enzyme, and it lyses gram-positive bacteria. 	
Lysozyme from chicken egg white can also be used for the research of HIV infection and pulmonary emphysema   . |  
 
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                                    - HY-N15551
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                                                |  | Bacterial | Infection |  
                                                | Armeniaspirol C is a potent antibacterial agent targeting Gram-positive bacteria. Armeniaspirol C is is promising for research of infections caused by multidrug-resistant Gram-positive bacteria . |  
 
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                                    - HY-B1466A
- 
                                        
                                            
                                                | BAY-f 1353 | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Mezlocillin (BAY-f 1353) is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin is active against both gram-negative and gram-positive bacteria. Mezlocillin can be used in bacterial infection research  . |  
 
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                                    - HY-117660R
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                                                | U-10149 (Standard) | Reference Standards
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Lincomycin (Standard) is the analytical standard of Lincomycin. This product is intended for research and analytical applications. Lincomycin, a lincosamide antibiotic, is an antimicrobial agent used for the research of Gram-positive bacteria infections . |  
 
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                                    - HY-106882
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                                                | MDL 62879 | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection  . |  
 
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                                    - HY-B1466R
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                                                | BAY-f 1353 sodium (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Mezlocillin (sodium) (Standard) is the analytical standard of Mezlocillin (sodium). This product is intended for research and analytical applications. Mezlocillin (BAY-f 1353) sodium is a β-lactam antibiotic, a semisynthetic and extended-spectrum antibiotic. Mezlocillin sodium is active against both gram-negative and gram-positive bacteria. Mezlocillin sodium can be used in bacterial infection research[1][2]. |  
 
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                                    - HY-W923644
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                                                | Aegelinol; (-)-Smyrinol | Bacterial | Infection |  
                                                | (-)-Decursinol (Aegelinol; (-)-Smyrinol) is a natural pyranocoumarin compound tant can be isolated from the roots of Apiaceae plants such as Ferulago campestris. (-)-Decursinol inhibits both Gram-positive bacteria (Staphylococcus aureus ATCC 13709, Enterococcus faecalis ATCC 14428) and Gram-negative bacteria (Salmonella typhii ATCC 19430, Enterobacter cloacae ATCC 10699, Enterobacter aerogenes ATCC 13048) with minimum inhibitory concentrations (MIC) ranging from 16 to 64 μg/mL. (-)-Decursinol possesses antioxidant activity. (-)-Decursinol can be used for the study of bacterial infections . |  
 
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                                    - HY-B1210
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                                                |  | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Pipemidic acid , a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid inhibits DNA gyrase. Pipemidic acid is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid can be used for the research of intestinal, urinary, and biliary tract infections  . |  
 
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                                    - HY-118951
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                                                |  | Bacterial | Infection |  
                                                | VU0038882 is a small-molecule activator of coproporphyrinogen oxidase (CgoX). VU0038882 can activate CgoX from Gram-Positive bacteria in vitro. VU0038882 can be used for the research of skin and soft tissue infections (SSTIs)  . |  
 
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                                    - HY-B0159
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                                                | Q-35 | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections  . |  
 
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                                    - HY-B1210R
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                                                |  | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Pipemidic acid (Standard) is the analytical standard of Pipemidic acid. This product is intended for research and analytical applications. Pipemidic acid , a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid inhibits DNA gyrase. Pipemidic acid is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid can be used for the research of intestinal, urinary, and biliary tract infections  . |  
 
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                                    - HY-B0159A
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                                                | Q-35 dihydrate | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Balofloxacin dihydrate (Q-35 dihydrate) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin dihydrate can be used for the research of respiratory, intestinal, and urinary tract infections  . |  
 
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                                    - HY-B0159R
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                                                | Q-35 (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Balofloxacin (Standard) is the analytical standard of Balofloxacin. This product is intended for research and analytical applications. Balofloxacin (Q-35) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections  . |  
 
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                                    - HY-101726
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                                                |  | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | DuP 105 is an orally active oxazolidinone with activity against Gram-positive bacteria. DuP 105 protects staphylococcal and streptococcal infections in mice. DuP 105 can be used for the study of infections caused by gram-positive bacteria  . |  
 
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                                    - HY-175795
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                                                |  | Tyrosinase
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Tyrosinase activator-1 (Compound 7A) is a Tyrosinase activator. Tyrosinase activator-1 significant antibacterial activity against gram-positive bacteria, such as MRSA, Staphylococcus aureus ATCC653 and Enterococcus faecium with MICs of 12.5-20  μM. Tyrosinase activator-1 activates tyrosinase by competitively occupying the binding site of L-DOPA on the surface of tyrosinase without interfering with the substrate binding at the active center. Tyrosinase activator-1 can be used for bacterial infections and antibiotics development research . |  
 
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                                    - HY-N14202
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                                                |  | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Maridomycin V is a macrolide antibiotic. Maridomycin Vhas the activity against Gram-positive bacteria and mycoplasma. Maridomycin V has the effect of protecting Gram-positive bacterial infection mice . |  
 
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                                    - HY-N14201
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                                                |  | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Maridomycin IV is a macrolide antibiotic. Maridomycin IV has the activity against Gram-positive bacteria and mycoplasma. Maridomycin IV has the effect of protecting Gram-positive bacterial infection mice . |  
 
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                                    - HY-N14203
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                                                |  | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Maridomycin VI is a macrolide antibiotic. Maridomycin VI has the activity against Gram-positive bacteria and mycoplasma. Maridomycin VI has the effect of protecting Gram-positive bacterial infection mice . |  
 
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                                    - HY-N14200
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                                                |  | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Maridomycin II is a macrolide antibiotic. Maridomycin II has the activity against Gram-positive bacteria and mycoplasma. Maridomycin II has the effect of protecting Gram-positive bacterial infection mice . |  
 
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                                    - HY-B0226A
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                                                | (E)-Nitrofural | Bacterial
                                                    
                                                        Parasite | Infection |  
                                                | (E)-Nitrofurazone ((E)-Nitrofural) is a topical broad-spectrum antibacterial agent effective against both Gram-negative and Gram-positive bacteria. (E)-Nitrofurazone also possesses antiprotozoal and antiparasitic activities. (E)-Nitrofurazone is commonly used in the research of superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, trypanosomiasis, and acute bacillary dysentery  . |  
 
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                                    - HY-A0256
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                                                |  | Beta-lactamase
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias . |  
 
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                                    - HY-B1150
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                                                |  | Bacterial
                                                    
                                                        SARS-CoV
                                                    
                                                        Antibiotic | Infection
                                                    
                                                        Cancer |  
                                                | Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency   . |  
 
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                                    - HY-125608
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                                                | Lipiarmycin B3 | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Tiacumicin C (Lipiarmycin B3) is an antibiotic with activity against Gram-positive bacteria. Tiacumicin C is employed in research related to bacterial infections . |  
 
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                                    - HY-112959
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                                                | TD-6424 | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Telavancin (TD-6424) is a semisynthetic lipoglycopeptide vancomycin-derivative, is a novel antimicrobial agent developed by Theravance for overcoming resistant Gram-positive bacterial infections, specifically methicillin-resistant Staphylococcus aureus (MRSA). Telavancin disrupts cell membrane integrity, can be used for research of complicated skin and skin structure infections (cSSSIs) caused by Gram-positive bacteria . |  
 
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                                    - HY-B1282A
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                                                |  | Bacterial
                                                    
                                                        Parasite
                                                    
                                                        Antibiotic | Infection |  
                                                | Sulfaquinoxaline sodium salt is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections  . |  
 
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                                    - HY-B1282
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                                                |  | Bacterial
                                                    
                                                        Parasite
                                                    
                                                        Antibiotic | Infection |  
                                                | Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections  . |  
 
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                                    - HY-N15095
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                                                |  | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Parasite | Infection |  
                                                | Aplasmomycin is a boron-containing macrodiolide antibiotic. Aplasmomycin shows antimicrobial activity against Gram-positive bacteria and exhibits inhibitory activity against plasmodium infections in vivo . |  
 
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                                    - HY-A0256R
- 
                                        
                                            
                                                |  | Beta-lactamase
                                                    
                                                        Reference Standards
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Clavulanic acid (Standard) is the analytical standard of Clavulanic acid. This product is intended for research and analytical applications. Clavulanic acid is a naturally occurring powerful bacterial β-lactamases inhibitor for research of infections caused by bacteria, including infections of the ears. Clavulanic acid is active against a wide spectrum of gram-positive and gram-negative bacterias[1]. |  
 
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                                    - HY-B0474
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                                                |  | Antibiotic
                                                    
                                                        Bacterial | Infection
                                                    
                                                        Cancer |  
                                                | Tetracycline hydrochloride is a broad-spectrum antibiotic with oral activity. Tetracycline hydrochloride exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline hydrochloride can be used for the research of infections . |  
 
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                                    - HY-125654
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                                                |  | Bacterial | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Olanexidine is an antibacterial agent. Olanexidine is active against a wide range of bacteria, imcluding both Gram-positive and Gram-negative bacteria Olanexidine is also an antiseptic. Olanexidine can be used in the research of infection and inflammation   . |  
 
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                                    - HY-A0107
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                                                | 
                                                        
                                                            Tetracycline
                                                            
                                                        
                                                        
                                                            
                                                                
                                                                    Maximum Cited Publications 45 Publications Verification | Antibiotic
                                                    
                                                        Bacterial | Infection
                                                    
                                                        Cancer |  
                                                | Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections . |  
 
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                                    - HY-12888
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                                                |  | Topoisomerase
                                                    
                                                        Bacterial | Infection |  
                                                | AZD5099, an antibacterial agent, is a potent and selective bacterial topoisomerase II inhibitor. AZD5099 potently inhibits the infections caused by Gram-positive and fastidious Gram-negative bacteria . |  
 
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                                    - HY-B0395C
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                                                | DU6859a hydrate | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections    . |  
 
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                                    - HY-B1150R
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                                                |  | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        SARS-CoV
                                                    
                                                        Antibiotic | Infection
                                                    
                                                        Cancer |  
                                                | Clofoctol (Standard) is the analytical standard of Clofoctol. This product is intended for research and analytical applications. Clofoctol is a bacteriostatic antibiotic. Clofoctol is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. Clofoctol is only functional against Gram-positive bacteria and can penetrate into human lung tissue. Clofoctol is also an inhibitor of prostate cancer. Clofoctol has antiviral potency   . |  
 
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                                    - HY-B0220H
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                                                |  | DNA/RNA Synthesis
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Erythromycin hydrochloride is a protein synthesis inhibitor with activity against the growth of both Gram-negative and Gram-positive bacteria. Erythromycin hydrochloride is commonly used in biomedicine to inhibit diseases caused by bacterial infections. Erythromycin hydrochloride is also involved in the inhibition of mammalian mRNA splicing. The application range of erythromycin hydrochloride includes respiratory tract infections, skin infections, and other infections caused by sensitive bacteria . |  
 
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                                    - HY-N7139
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                                                | Benzylpenicillin | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Penicillin G is a potent penicillinantibiotic. Penicillin G can be used for bacterial infection. Penicillin G has potent activity against all Gram-positive bacteria and Gram-negative cocci  . |  
 
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                                    - HY-N14217
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                                                |  | Fungal
                                                    
                                                        HIV | Infection |  
                                                | Eulicin is an antifungal agent that inhibits human immunodeficiency virus (HIV) infection and replication. Eulicin is broadly active against both Gram-positive and Gram-negative bacteria and can be found in Streptomyces  . |  
 
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                                    - HY-125654C
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                                                |  | Bacterial | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Olanexidine gluconate is an antibacterial agent. Olanexidine gluconate is active against a wide range of bacteria, imcluding both Gram-positive and Gram-negative bacteria Olanexidine gluconate is also an antiseptic. Olanexidine gluconate can be used in the research of infection and inflammation   . |  
 
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                                    - HY-125654B
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                                                |  | Bacterial | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Olanexidine hydrochloride semihydrate is an antibacterial agent. Olanexidine hydrochloride semihydrate is active against a wide range of bacteria, imcluding both Gram-positive and Gram-negative bacteria Olanexidine hydrochloride semihydrate is also an antiseptic. Olanexidine hydrochloride semihydrate can be used in the research of infection and inflammation   . |  
 
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                                    - HY-B0395A
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                                                | DU6859a hydrochloride | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Sitafloxacin (DU6859a) hydrochloride is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin hydrochloride shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin hydrochloride can be used for the research of respiratory tract infection and urinary tract infection  . |  
 
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                                    - HY-B0395
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                                                | DU6859a | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection  . |  
 
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                                    - HY-B0395B
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                                                | DU6859a monohydrate | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Sitafloxacin (DU6859a) monohydrate is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin monohydrate shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin monohydrate can be used for the research of respiratory tract infection and urinary tract infection  . |  
 
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                                    - HY-113640
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                                                |  | Bacterial | Infection |  
                                                | BC-7013 is a novel semi-synthetic pleuromutilin derivative. BC-7013 has excellent activity against Gram-positive pathogenic bacteria. BC-7013 exhibits potent antibacterial properties against both Staphylococcus, Streptococcus and penicillin-resistant Streptococcus pneumoniae. BC-7013 has activity against Gram-positive pathogenic bacteria, BC-7013 is useful in the research of acute bacterial skin and skin structure infection (ABSSSI) . |  
 
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                                    - HY-B1282S
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                                                |  | Isotope-Labeled Compounds
                                                    
                                                        Bacterial
                                                    
                                                        Parasite
                                                    
                                                        Antibiotic | Infection |  
                                                | Sulfaquinoxaline-d4 is the deuterium labeled Sulfaquinoxaline. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections  . |  
 
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                                    - HY-B0213
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                                                | Sulfametoxydiazine;  5-Methoxysulfadiazine;  NSC 683528 | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections  . |  
 
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                                    - HY-B0958
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                                                | BRL-4910A;  Pseudomonic acid | Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Aminoacyl-tRNA Synthetase | Infection
                                                    
                                                        Endocrinology |  
                                                | Mupirocin is an antibiotic. Mupirocin inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis      . |  
 
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                                    - HY-B1924
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                                                | N-Demethylvancomycin monohydrochloride; NVCM monohydrochloride | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Norvancomycin hydrochloride is a cell wall synthesis inhibitor targeting peptidoglycan precursors of Gram-positive bacteria and cannot pass the blood-brain barrier. Norvancomycin hydrochloride can competitively bind to peptidoglycan precursors, irreversibly inhibit bacterial cell wall synthesis, and exert antibacterial activity. Norvancomycin hydrochloride is mainly used in the study of Gram-positive bacterial infections, especially infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE). Norvancomycin hydrochloride can also be incorporated into the bionic calcium phosphate coating of titanium implants to enhance antibacterial activity and inhibit postoperative orthopedic infections  . |  
 
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                                    - HY-B0126
- 
                                        
                                            
                                                |  | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Marbofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma   . |  
 
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                                    - HY-B0977
- 
                                        
                                            
                                                | Dicloxacillin sodium salt monohydrate | Bacterial
                                                    
                                                        Antibiotic | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to treat infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus   . |  
 
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                                    - HY-B0126A
- 
                                        
                                            
                                                |  | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Marbofloxacin hydrochloride is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin hydrochloride can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma   . |  
 
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                                    - HY-B0136
- 
                                        
                                            
                                                | FK-482;  CI-983 | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin  . |  
 
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                                    - HY-B0395CR
- 
                                        
                                            
                                                | DU6859a hydrate (Standard) | Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Reference Standards | Infection |  
                                                | Sitafloxacin (hydrate) (Standard) is the analytical standard of Sitafloxacin (hydrate). This product is intended for research and analytical applications. Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections    . |  
 
- 
                                        
                                        
                                              
                                    - HY-W013766
- 
                                        
                                            
                                                |  | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections  . |  
 
- 
                                        
                                        
                                              
                                    - HY-A0107R
- 
                                        
                                            
                                                |  | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection
                                                    
                                                        Cancer |  
                                                | Tetracycline (Standard) is the analytical standard of Tetracycline. This product is intended for research and analytical applications. Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections . |  
 
- 
                                        
                                        
                                              
                                    - HY-105284
- 
                                        
                                            
                                                | CP-70429 | Beta-lactamase
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Sulopenem (CP-70429) is an orally active, parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. Sulopenem has the potential for urinary tract infections and intra-abdominal infections treatment. Sulopenem is inactive against Pseudomonas aeruginosa and Xanthomonas maltophilia   . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1282R
- 
                                        
                                            
                                                |  | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Parasite
                                                    
                                                        Antibiotic | Infection |  
                                                | Sulfaquinoxaline (Standard) is the analytical standard of Sulfaquinoxaline. This product is intended for research and analytical applications. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections  . |  
 
- 
                                        
                                        
                                              
                                    - HY-105284A
- 
                                        
                                            
                                                | CP-70429 sodium | Bacterial
                                                    
                                                        Antibiotic | Inflammation/Immunology |  
                                                | Sulopenem (sodium)(CP-70429 (sodium)) is an orally active, parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. Sulopenem has the potential for urinary tract infections and intra-abdominal infections treatment. Sulopenem is inactive against Pseudomonas aeruginosa and Xanthomonas maltophilia   . |  
 
- 
                                        
                                        
                                              
                                    - HY-159688
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | Cefditoren is an orally active antibiotic with broad-spectrum antibacterial activity, capable of inhibiting both Gram-negative and Gram-positive bacteria. It has a MIC50 of 0.25-0.5 mg/L against Streptococcus pneumoniae strains. Cefditoren is effective against respiratory tract infections and skin infections   . |  
 
- 
                                        
                                        
                                              
                                    - HY-W108875
- 
                                        
                                            
                                                | BRL-4910A lithium; Pseudomonic acid lithium | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Aminoacyl-tRNA Synthetase | Infection
                                                    
                                                        Endocrinology |  
                                                | Mupirocin lithium is an antibiotic. Mupirocin lithium inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin lithium has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin lithium can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis      . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1369
- 
                                        
                                            
                                                | N-Formimidoyl thienamycin monohydrate; MK0787 monohydrate | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections   . |  
 
- 
                                        
                                        
                                              
                                    - HY-157482
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | EBP-59 is a bacterial inhibitor with antibiofilm activity against Gram-positive bacteria. EBP-59 is effective against Staphylococcus aureus and MRSA (methicillin–resistant staphylococcus aureus). EBP-59 can be used to study bacterial infections . |  
 
- 
                                        
                                        
                                              
                                    - HY-A0107S2
- 
                                        
                                            
                                                |  | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Isotope-Labeled Compounds | Infection |  
                                                | Tetracycline-d6-1 is deuterated labeled Tetracycline (HY-A0107). Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections . |  
 
- 
                                        
                                        
                                              
                                    - HY-105088A
- 
                                        
                                            
                                                | MSI 78 | Bacterial | Infection |  
                                                | Pexiganan acetate (MSI 78) is the acetate salt form of Pexiganan (HY-105088). Pexiganan acetate is an orally active broad-spectrum antimicrobial peptide, which inhibits 99% gram-positive and Gram-negative aerobic bacteria through disruption of cell membrane/cells permeability. Pexiganan acetate can be used in the research of infections, such as diabetic foot ulcer infections . |  
 
- 
                                        
                                        
                                              
                                    - HY-19915
- 
                                        
                                            
                                                | MRX-I | Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Monoamine Oxidase | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Contezolid (MRX-I), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid (MRX-I) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI)  . |  
 
- 
                                        
                                        
                                              
                                    - HY-10394
- 
                                        
                                            
                                                | PNU-100766 | Bacterial
                                                    
                                                        Antibiotic | Infection
                                                    
                                                        Cancer |  
                                                | Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics   . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1369A
- 
                                        
                                            
                                                | N-Formimidoyl thienamycin;  MK0787 | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections   . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0724A
- 
                                        
                                            
                                                | T-3762;  Pazufloxacin methanesulfonate;  Pazufloxacin mesilate | Bacterial
                                                    
                                                        DNA/RNA Synthesis | Infection |  
                                                | Pazufloxacin mesylate is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin mesylate inhibits DNA gyrase with IC50 values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). Pazufloxacin mesylate exhibits broad-spectrum antimicrobial activity, with MIC90 values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin mesylate is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia     . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0724B
- 
                                        
                                            
                                                | T3761 | Bacterial
                                                    
                                                        DNA/RNA Synthesis | Infection |  
                                                | Pazufloxacin is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin inhibits DNA gyrase with IC50 values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). Pazufloxacin exhibits broad-spectrum antimicrobial activity, with MIC90 values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia     . |  
 
- 
                                        
                                        
                                              
                                    - HY-P5724
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | Nv-CATH is an antibacterial peptide of frog origin. Nv-CATH has broad-spectrum antibacterial activity against gram-positive and gram-negative bacteria. Nv-CATH significantly protects mice from fatal infections caused by Staphylococcus aureus. Nv-CATH protects mice from bacterial infection through antimicrobial immunoregulatory duality . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0510
- 
                                        
                                            
                                                |  | Antifolate
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Influenza Virus | Infection
                                                    
                                                        Cancer |  
                                                | Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc    . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0510B
- 
                                        
                                            
                                                |  | Antifolate
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Influenza Virus | Infection
                                                    
                                                        Cancer |  
                                                | Trimethoprim hydrochloride is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim hydrochloride is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim hydrochloride has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim hydrochloride can inhibit infection of Influenza A virus in chick embryo when combinated with zinc    . |  
 
- 
                                        
                                        
                                              
                                    - HY-162171
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | Antibacterial agent 179 (Compound 23) is a potent antibacterial agent, which effectively kills both Gram-negative and Gram-positive bacteria. Antibacterial agent 179 shows potent in vivo antibacterial efficacy in murine corneal infection models caused by Staphylococcus aureus or Pseudomonas aeruginosa . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1002
- 
                                        
                                            
                                                |  | Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        DNA/RNA Synthesis | Infection |  
                                                | Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice   . |  
 
- 
                                        
                                        
                                              
                                    - HY-12480
- 
                                        
                                            
                                                | GSK 1322322 | Bacterial | Infection |  
                                                | Lanopepden (GSK 1322322) is a peptidyl peptidase (PDF) inhibitor. Lanopepden inhibits PDF activity, preventing bacterial protein synthesis, thereby exerting antibacterial activity. Lanopepden is primarily effective against Gram-positive bacteria. Lanopepden is used in the study of acute bacterial skin and skin structure infections . |  
 
- 
                                        
                                        
                                              
                                    - HY-116598
- 
                                        
                                            
                                                | GSK 1322322 mesylate | Bacterial | Infection |  
                                                | Lanopepden mesylate (GSK 1322322 mesylate) is a peptide deformase (PDF) inhibitor. Lanopepden mesylate has antibacterial activity by inhibiting the activity of PDF, preventing the correct synthesis of bacterial proteins. Lanopepden mesylate mainly targets Gram-positive bacteria. Lanopepden mesylate can be used in the study of acute bacterial skin and skin structural infections . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0024
- 
                                        
                                            
                                                | NM441 | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Prulifloxacin (NM441) is an orally active fluoroquinolone antibiotic with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a proagent of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis  . |  
 
- 
                                        
                                        
                                              
                                    - HY-162923
- 
                                        
                                            
                                                |  | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Antibacterial agent 244 is an orally active compound with broad-spectrum antibacterial activity, primarily targeting Gram-positive bacteria, with a MIC value of 1–4 μg/mL and low hemolytic toxicity (HC50 of 111.6 μg/mL). Antibacterial agent 244 disrupts bacterial transmembrane potential, increases membrane permeability, leading to leakage of cellular contents such as DNA and proteins, ultimately causing bacterial death. Antibacterial agent 244 can be used in research related to Gram-positive bacterial infections . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0395S
- 
                                        
                                            
                                                | DU6859a-d4 | Isotope-Labeled Compounds
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Sitafloxacin-d4 (DU6859a-d4) is deuterium labeled Sitafloxacin. Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection  . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0126S
- 
                                        
                                            
                                                |  | Isotope-Labeled Compounds
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Marbofloxacin-d8 is the deuterium labeled Marbofloxacin. Marbofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma   . |  
 
- 
                                        
                                        
                                              
                                    - HY-19915B
- 
                                        
                                            
                                                | MRX-4 sodium | Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Monoamine Oxidase | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Contezolid acefosamil sodium (MRX-4), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid acefosamil sodium (MRX-4) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI)  . |  
 
- 
                                        
                                        
                                              
                                    - HY-18324
- 
                                        
                                            
                                                | REP-3123 | Antibiotic | Inflammation/Immunology |  
                                                | CRS3123 is a potent and orally active narrow-spectrum antibiotic. CRS3123 inhibits bacterial methionyl-tRNA synthetase. CRS3123 has potent activity against Clostridium difficile (C. difficile) and aerobic Gram-positive bacteria but little activity against Gram-negative bacteria, including anaerobes. CRS3123 has the potential for the research of C. difficile infections . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0958R
- 
                                        
                                            
                                                | BRL-4910A (Standard); Pseudomonic acid (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Aminoacyl-tRNA Synthetase | Infection
                                                    
                                                        Endocrinology |  
                                                | Mupirocin (Standard) is the analytical standard of Mupirocin (HY-B0958). This product is intended for research and analytical applications. Mupirocin is an antibiotic. Mupirocin inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis      . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0136R
- 
                                        
                                            
                                                | FK-482 (Standard); CI-983 (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Cefdinir (Standard) is the analytical standard of Cefdinir. This product is intended for research and analytical applications. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin  . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0510C
- 
                                        
                                            
                                                |  | Antifolate
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection
                                                    
                                                        Cancer |  
                                                | Trimethoprim lactate is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim lactate is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim lactate has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim lactate can inhibit infection of Influenza A virus in chick embryo when combinated with zinc    . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0510A
- 
                                        
                                            
                                                |  | Antifolate
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Influenza Virus | Infection
                                                    
                                                        Cancer |  
                                                | Trimethoprim sulfate is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim sulfate is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim sulfate has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim sulfate can inhibit infection of Influenza A virus in chick embryo when combinated with zinc    . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0126AS
- 
                                        
                                            
                                                |  | Isotope-Labeled Compounds
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Marbofloxacin-d8 (hydrochloride) is deuterium labeled Marbofloxacin (hydrochloride). Marbofloxacin hydrochloride is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin hydrochloride can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma    . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0510S
- 
                                        
                                            
                                                |  | Antifolate
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Trimethoprim-d9 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment   . |  
 
- 
                                        
                                        
                                              
                                    - HY-N12496
- 
                                        
                                            
                                                |  | Fungal
                                                    
                                                        Bacterial | Infection |  
                                                | Di-O-methylhonokiol is a natural phenolic compound that can be isolated from magnolia flowers. Di-O-methylhonokiol has significant antibacterial activity against Gram-positive bacteria, acid-fast bacilli, and yeast-like and filamentous fungi. Di-O-methylhonokiol can be used in the study of fungal infections . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0510S2
- 
                                        
                                            
                                                |  | Antifolate
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Trimethoprim-d3is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment   . |  
 
- 
                                        
                                        
                                              
                                    - HY-17395S
- 
                                        
                                            
                                                | TDT 067-d3 hydrochloride | Isotope-Labeled Compounds
                                                    
                                                        Fungal
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Terbinafine-d3 hydrochloride is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM  . Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria . |  
 
- 
                                        
                                        
                                              
                                    - HY-17395AS
- 
                                        
                                            
                                                | TDT 067-d7 | Isotope-Labeled Compounds
                                                    
                                                        Fungal
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Terbinafine-d7 is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM  . Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria . |  
 
- 
                                        
                                        
                                              
                                    - HY-A0097
- 
                                        
                                            
                                                | Antibiotic MDL-507;  MDL-507 | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Teicoplanin is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity  . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0977R
- 
                                        
                                            
                                                | Dicloxacillin sodium salt monohydrate (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Dicloxacillin (Sodium hydrate) (Standard) is the analytical standard of Dicloxacillin (Sodium hydrate). This product is intended for research and analytical applications. Dicloxacillin Sodium hydrate (Dicloxacillin sodium salt monohydrate) is a narrow-spectrum β-Lactam antibiotic of the penicillin class, is used to treat infections caused by susceptible Gram-positive bacteria, active against beta-lactamase-producing organisms such as Staphylococcus aureus   . |  
 
- 
                                        
                                        
                                              
                                    - HY-A0097A
- 
                                        
                                            
                                                | Antibiotic MDL-507 sodium; MDL-507 sodium | Antibiotic
                                                    
                                                        HIV
                                                    
                                                        SARS-CoV | Infection |  
                                                | Teicoplanin sodium is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin sodium shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity  . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0126R
- 
                                        
                                            
                                                |  | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Marbofloxacin (Standard) is the analytical standard of Marbofloxacin. This product is intended for research and analytical applications. Marbofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma   . |  
 
- 
                                        
                                        
                                              
                                    - HY-14865B
- 
                                        
                                            
                                                | PTK 0796 tosylate; Amadacycline tosylate | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections    . |  
 
- 
                                        
                                        
                                              
                                    - HY-14865C
- 
                                        
                                            
                                                | PTK0796 hydrochloride;  Amadacycline hydrochloride | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections    . |  
 
- 
                                        
                                        
                                              
                                    - HY-14865
- 
                                        
                                            
                                                | PTK 0796;  Amadacycline | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections    . |  
 
- 
                                        
                                        
                                              
                                    - HY-14865A
- 
                                        
                                            
                                                | PTK 0796 mesylate;  Amadacycline mesylate | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Omadacycline (PTK 0796) mesylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline mesylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline mesylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline mesylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections    . |  
 
- 
                                        
                                        
                                              
                                    - HY-W013766R
- 
                                        
                                            
                                                |  | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Pipemidic acid (trihydrate) (Standard) is the analytical standard of Pipemidic acid (trihydrate). This product is intended for research and analytical applications. Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections  . |  
 
- 
                                        
                                        
                                              
                                    - HY-132242R
- 
                                        
                                            
                                                | SFN-NAC (Standard) | Reference Standards
                                                    
                                                        HDAC
                                                    
                                                        Apoptosis
                                                    
                                                        Drug Metabolite | Cancer |  
                                                | Pipemidic acid (trihydrate) (Standard) is the analytical standard of Pipemidic acid (trihydrate). This product is intended for research and analytical applications. Pipemidic acid trihydrate, a derivative of Piromidic acid, is an antibacterial agent. Pipemidic acid trihydrate inhibits DNA gyrase. Pipemidic acid trihydrate is active against gram-negative bacteria including Pseudomonas aeruginosa as well as some gram-positive bacteria. Pipemidic acid trihydrate can be used for the research of intestinal, urinary, and biliary tract infections  . |  
 
- 
                                        
                                        
                                              
                                    - HY-105048A
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | Omiganan pentahydrochloride is a cationic peptide compound with a broad antibacterial profile. Omiganan pentahydrochloride is capable of inhibiting a variety of bacteria, including yeast, and is active against both gram-positive and gram-negative bacteria. Omiganan pentahydrochloride is able to interact with the bacterial cell membrane, causing the destruction of the cell membrane and the death of the bacteria. Omiganan pentahydrochloride can be used for the study of antimicrobial activity against pathogens commonly associated with catheter-associated infections, including strains with drug-resistant phenotypes . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1002S
- 
                                        
                                            
                                                |  | Isotope-Labeled Compounds
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        DNA/RNA Synthesis | Infection |  
                                                | Oxolinic acid-d5 is the deuterium labeled Oxolinic acid. Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice   . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0213S
- 
                                        
                                            
                                                | Sulfametoxydiazine-d4;  5-Methoxysulfadiazine-d4;  NSC 683528-d4 | Isotope-Labeled Compounds
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Sulfameter-d4 (Sulfametoxydiazine-d4) is the deuterium labeled Sulfameter (HY-B0213) . Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1369R
- 
                                        
                                            
                                                | N-Formimidoyl thienamycin monohydrate (Standard); MK0787 monohydrate (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Imipenem (monohydrate) (Standard) is the analytical standard of Imipenem (monohydrate). This product is intended for research and analytical applications. Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections   . |  
 
- 
                                        
                                        
                                              
                                    - HY-10394R
- 
                                        
                                            
                                                | PNU-100766 (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Linezolid (Standard) is the analytical standard of Linezolid. This product is intended for research and analytical applications. Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics   . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0510R
- 
                                        
                                            
                                                |  | Reference Standards
                                                    
                                                        Antifolate
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Influenza Virus | Infection |  
                                                | Trimethoprim (Standard) is the analytical standard of Trimethoprim. This product is intended for research and analytical applications. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc    . |  
 
- 
                                        
                                        
                                              
                                    - HY-N7123
- 
                                        
                                            
                                                | Sulphacetamide | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Fungal | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic. Sulfacetamide has antifungal and antibacterial activities. Sulfacetamide is employed as a topical formulation in various ophthalmic, dermatological, and hair solutions against bacterial infections, acne and scalp conditions. Sulfacetamide targets bacterial folic acid synthesis and is effective against various gram-positive and gram-negative bacteria. Sulfacetamide inhibits the synthesis of both dihydro-folic acid and para-aminobenzoic acid. Sulfacetamide can be used for the study of ocular infections  . |  
 
- 
                                        
                                        
                                              
                                    - HY-W108875R
- 
                                        
                                            
                                                | BRL-4910A lithium (Standard); Pseudomonic acid lithium (Standard) | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Reference Standards
                                                    
                                                        Aminoacyl-tRNA Synthetase | Infection
                                                    
                                                        Endocrinology |  
                                                | Mupirocin (lithium) (Standard) is the analytical standard of Mupirocin lithium (HY-W108875). This product is intended for research and analytical applications. Mupirocin lithium is an antibiotic. Mupirocin lithium inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin lithium has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae). Mupirocin lithium can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis      . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0724AR
- 
                                        
                                            
                                                | T-3762 (Standard); Pazufloxacin methanesulfonate (Standard); Pazufloxacin mesilate (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        DNA/RNA Synthesis | Infection |  
                                                | Pazufloxacin (mesylate) (Standard) is the analytical standard of Pazufloxacin mesylate (HY-B0724A). This product is intended for research and analytical applications. Pazufloxacin mesylate is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin mesylate inhibits DNA gyrase with IC50 values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). Pazufloxacin mesylate exhibits broad-spectrum antimicrobial activity, with MIC90 values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin mesylate is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia     . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0724BS
- 
                                        
                                            
                                                | T3761-d4 | Isotope-Labeled Compounds
                                                    
                                                        Bacterial
                                                    
                                                        DNA/RNA Synthesis | Infection |  
                                                | Pazufloxacin-d4 is deuterium labeled Pazufloxacin (HY-B0724B). Pazufloxacin is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin inhibits DNA gyrase with IC50 values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). Pazufloxacin exhibits broad-spectrum antimicrobial activity, with MIC90 values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia      . |  
 
- 
                                        
                                        
                                              
                                    - HY-14865CR
- 
                                        
                                            
                                                | PTK0796 hydrochloride (Standard); Amadacycline hydrochloride (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Omadacycline (hydrochloride) (Standard) is the analytical standard of Omadacycline (hydrochloride). This product is intended for research and analytical applications. Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections[1][2][3][4]. |  
 
- 
                                        
                                        
                                              
                                    - HY-B1257
- 
                                        
                                            
                                                | Sodium cefmetazole | Bacterial
                                                    
                                                        Antibiotic | Infection
                                                    
                                                        Cancer |  
                                                | Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections   . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1595
- 
                                        
                                            
                                                | CS 1170 | Antibiotic
                                                    
                                                        Bacterial | Infection
                                                    
                                                        Cancer |  
                                                | Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections   . |  
 
- 
                                        
                                        
                                              
                                    - HY-P2320
- 
                                        
                                            
                                                |  | Bacterial | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release  . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0213R
- 
                                        
                                            
                                                | Sulfametoxydiazine (Standard); 5-Methoxysulfadiazine (Standard); NSC 683528 (Standard) | Reference Standards
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Sulfameter (Standard) (Sulfametoxydiazine (Standard)) is the analytical standard of Sulfameter (HY-B0213). This product is intended for research and analytical applications. Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections  . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1002R
- 
                                        
                                            
                                                |  | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        DNA/RNA Synthesis | Infection |  
                                                | Oxolinic acid (Standard) is the analytical standard of Oxolinic acid. This product is intended for research and analytical applications. Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice   . |  
 
- 
                                        
                                        
                                              
                                    - HY-139554A
- 
                                        
                                            
                                                | KBP-7072 TFA | Bacterial | Infection |  
                                                | Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections  . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0510S3
- 
                                        
                                            
                                                |  | Isotope-Labeled Compounds
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Antifolate
                                                    
                                                        Influenza Virus | Others |  
                                                | Trimethoprim- 13C3 is the deuterium labeled Trimethoprim (HY-B0510) . Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc    . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0024R
- 
                                        
                                            
                                                | NM441 (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Prulifloxacin (Standard) is the analytical standard of Prulifloxacin. This product is intended for research and analytical applications. Prulifloxacin (NM441) is an orally active fluoroquinolone antibiotic with a broad spectrum of activity against Gram-positive and -negative bacteria. Prulifloxacin is a proagent of a thiazeto-quinoline carboxylic acid derivative Ulifloxacin (NM394). Prulifloxacin has the potential for lower urinary tract infections and exacerbations of chronic bronchitis  . |  
 
- 
                                        
                                        
                                              
                                    - HY-10394S1
- 
                                        
                                            
                                                | PNU-100766-d8 | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Isotope-Labeled Compounds | Infection |  
                                                | PNU-100766-d8 is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics   . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0213S1
- 
                                        
                                            
                                                | Sulfametoxydiazine-13C6; 5-Methoxysulfadiazine-13C6;  NSC 683528-13C6 | Isotope-Labeled Compounds
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Sulfameter- 13C6 (Sulfametoxydiazine- 13C6) is the  13C6 labeled Sulfameter (HY-B0213). Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections   . |  
 
- 
                                        
                                        
                                              
                                    - HY-N7224
- 
                                        
                                            
                                                | SF-1854 | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | N-Formylfortimicin A (SF-1854) is an aminoglycoside antibiotic with broad-spectrum antibacterial activity. It primarily acts on bacterial ribosomes to inhibit protein synthesis and exhibits notable inhibitory effects against various Gram-positive and Gram-negative bacteria (e.g., E. coli with a MIC of 12.5-50 μg/mL), making it a potential candidate for research on bacterial infection-related diseases . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0455
- 
                                        
                                            
                                                | SC47111A hydrochloride; NY-198 hydrochloride | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Topoisomerase
                                                    
                                                        Reactive Oxygen Species (ROS)
                                                    
                                                        Apoptosis | Infection
                                                    
                                                        Endocrinology
                                                    
                                                        Cancer |  
                                                | Lomefloxacin hydrochloride (NY-198 hydrochloride) is an orally active difluoroquinolone antibiotic. Lomefloxacin hydrochloride prevents DNA supercoiling and replication by inhibiting bacterial topoisomerase II. Lomefloxacin hydrochloride induces ROS production and Apoptosis. Lomefloxacin hydrochloride has broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria. Lomefloxacin hydrochloride has anticancer effects against melanoma. Lomefloxacin hydrochloride can be used in the study of systemic bacterial infections (such as Salmonella typhimurium infections), skin and melanoma       . |  
 
- 
                                        
                                        
                                              
                                    - HY-16764A
- 
                                        
                                            
                                                | JNJ-Q2 hydrochloride | Bacterial | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Acorafloxacin hydrochloride (JNJ-Q2  hydrochloride) is a broad-spectrum fluoroquinolone anti-bacterial drug being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia . 
Acorafloxacin hydrochloride (Avarofloxacin ) is an aminoethylidenylpiperidine fluoroquinolone that demonstrates antibacterial effect against numerous Gram-positive bacteria with a mean 0.12 mg/L MIC90 value . 
Acorafloxacin hydrochloride (JNJ-Q2) has potential for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections . |  
 
- 
                                        
                                        
                                              
                                    - HY-139554
- 
                                        
                                            
                                                | KBP-7072 | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Zifanocycline (KBP-7072) is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits the normal function of the bacterial ribosome. Zifanocycline exhibits a broad spectrum of in vitro antibacterial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline is available in both oral and injectable formulations. Zifanocycline can be used for the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections  . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0136S
- 
                                        
                                            
                                                | FK-482-13C,15N2;  CI-983-13C,15N2 | Isotope-Labeled Compounds
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Cefdinir- 13C, 15N2 (FK-482- 13C, 15N2) is  13C and  15N labeled Cefdinir. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin  . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1916
- 
                                        
                                            
                                                | Spiramycin B;  Spiramycin II;  Foromacidin B | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Parasite | Infection |  
                                                | Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection    . |  
 
- 
                                        
                                        
                                              
                                    - HY-14865R
- 
                                        
                                            
                                                | PTK 0796 (Standard); Amadacycline (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Omadacycline (Standard) is the analytical standard of Omadacycline. This product is intended for research and analytical applications. Omadacycline (PTK 0796), a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections    . |  
 
- 
                                        
                                        
                                              
                                    - HY-14865BR
- 
                                        
                                            
                                                | PTK 0796 tosylate (Standard); Amadacycline tosylate (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Omadacycline (tosylate) (Standard) is the analytical standard of Omadacycline (tosylate). This product is intended for research and analytical applications. Omadacycline (PTK 0796) tosylate, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline tosylate acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline tosylate possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections    . |  
 
- 
                                        
                                        
                                              
                                    - HY-16764
- 
                                        
                                            
                                                | JNJ-Q2 | Bacterial
                                                    
                                                        Antibiotic | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial agent being developed for the treatment of acute bacterial skin and skin-structure infections and community-acquired pneumonia with oral activity. Avarofloxacin (JNJ-Q2) is an aminoethylidenylpiperidine fluoroquinolone that demonstrates antibacterial effect against numerous Gram-positive bacteria with a mean 0.12 mg/L MIC90 value. Avarofloxacin (JNJ-Q2) has potential for treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections   . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1916R
- 
                                        
                                            
                                                | Spiramycin B (Standard); Spiramycin II (Standard); Foromacidin B (Standard) | Reference Standards
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Parasite | Infection |  
                                                | Acetylspiramycin (Standard) is the analytical standard of Acetylspiramycin. This product is intended for research and analytical applications. Acetylspiramycin (Spiramycin B) is an effective oral macrolide antibiotic produced by Streptomyces, It can inhibit the splenic lymphocyte transformation induced by phytohemagglutinin (PHA), LPS (HY-D1056) and antigen, reduce the procoagulant activity of macrophages, have good antibacterial effect on gram-positive bacteria, and is also an effective antigenic insect agent, which can be used to fight parasitic infection[1][2][3][4]. |  
 
- 
                                        
                                        
                                              
                                    - HY-139554AR
- 
                                        
                                            
                                                | KBP-7072 TFA (Standard) | Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Reference Standards | Infection |  
                                                | Zifanocycline (TFA) (Standard) is the analytical standard of Zifanocycline (TFA). This product is intended for research and analytical applications. Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections[1][2]. |  
 
- 
                                        
                                        
                                              
                                    - HY-175376
- 
                                        
                                            
                                                |  | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | QPyN16Th is an N-palmitoylated cationic thiazolidine antibiotic. QPyN16Th is selectively active against the Gram-positive bavteria E. faecalis, S. aureus and MRSA with an MIC of 1.95 μM over gram-negative bacteria. QPyN16Th can induce membrane permeabilization and depolarization and ROS production in MRSA. QPyN16Th increases the survival of zebrafish model of intramuscular MRSA infection . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1050
- 
                                        
                                            
                                                | SB-265805S;  LB-20304a | Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        DNA/RNA Synthesis
                                                    
                                                        Topoisomerase | Infection |  
                                                | Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections   . |  
 
- 
                                        
                                        
                                              
                                    - HY-146811
- 
                                        
                                            
                                                |  | Bacterial | Inflammation/Immunology |  
                                                | HSGN-94 is a potent antimicrobial agent with lipoteichoic acid (LTA) biosynthesis inhibition. HSGN-94 inhibits drug-resistant Gram-positive bacteria with MIC values of 0.25-2 μg/mL. HSGN-94 inhibits biofilm formation of MRSA and Vancomycin-resistant Enterococci. HSGN-94 also inhibits pro-inflammatory cytokines, exhibits in vivo efficacy in an MRSA murine wound infection model . |  
 
- 
                                        
                                        
                                              
                                    - HY-N6680
- 
                                        
                                            
                                                |  | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections [1][2]. |  
 
- 
                                        
                                        
                                              
                                    - HY-P10913
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | HYNIC-UBI29-41 is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41. HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1257R
- 
                                        
                                            
                                                | Sodium cefmetazole (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection
                                                    
                                                        Cancer |  
                                                | Cefmetazole (sodium) (Standard) is the analytical standard of Cefmetazole (sodium). This product is intended for research and analytical applications. Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections   . |  
 
- 
                                        
                                        
                                              
                                    - HY-N7123R
- 
                                        
                                            
                                                | Sulphacetamide (Standard) | Reference Standards
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Fungal | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Sulfacetamide (Standard) (Sulphacetamide (Standard)) is the analytical standard of Sulfacetamide (HY-N7123). This product is intended for research and analytical applications. Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic. Sulfacetamide has antifungal and antibacterial activities. Sulfacetamide is employed as a topical formulation in various ophthalmic, dermatological, and hair solutions against bacterial infections, acne and scalp conditions. Sulfacetamide targets bacterial folic acid synthesis and is effective against various gram-positive and gram-negative bacteria. Sulfacetamide inhibits the synthesis of both dihydro-folic acid and para-aminobenzoic acid. Sulfacetamide can be used for the study of ocular infections  . |  
 
- 
                                        
                                        
                                              
                                    - HY-N7101
- 
                                        
                                            
                                                | U-76,252;  CS-807 | Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Penicillin-binding protein (PBP) | Infection |  
                                                | Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases     . |  
 
- 
                                        
                                        
                                              
                                    - HY-A0111B
- 
                                        
                                            
                                                | Ro 15-8074 hydrochloride; Deacetoxycefotaxime hydrochloride | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Penicillin-binding protein (PBP)
                                                    
                                                        Drug Metabolite | Infection |  
                                                | Cefetamet (Ro 15-8074) hydrochloride is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet hydrochloride binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet hydrochloride has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet hydrochloride kills and lyses Treponema pallidum. Cefetamet hydrochloride can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis     . |  
 
- 
                                        
                                        
                                              
                                    - HY-A0111A
- 
                                        
                                            
                                                | Ro15-8074/001; Deacetoxycefotaxime sodium | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Penicillin-binding protein (PBP)
                                                    
                                                        Drug Metabolite | Infection |  
                                                | Cefetamet (Ro 15-8074) sodium is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet sodium binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet sodium has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet sodium kills and lyses Treponema pallidum. Cefetamet sodium can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis     . |  
 
- 
                                        
                                        
                                              
                                    - HY-A0111
- 
                                        
                                            
                                                | Ro 15-8074;  Deacetoxycefotaxime | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Penicillin-binding protein (PBP)
                                                    
                                                        Drug Metabolite | Infection |  
                                                | Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis     . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0455R
- 
                                        
                                            
                                                | SC47111A hydrochloride (Standard); NY-198 hydrochloride (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Topoisomerase
                                                    
                                                        Reactive Oxygen Species (ROS)
                                                    
                                                        Apoptosis | Infection
                                                    
                                                        Endocrinology
                                                    
                                                        Cancer |  
                                                | Lomefloxacin (hydrochloride) (Standard) is the analytical standard of Lomefloxacin hydrochloride (HY-B0455). This product is intended for research and analytical applications. Lomefloxacin hydrochloride (NY-198 hydrochloride) is an orally active difluoroquinolone antibiotic. Lomefloxacin hydrochloride prevents DNA supercoiling and replication by inhibiting bacterial topoisomerase II. Lomefloxacin hydrochloride induces ROS production and Apoptosis. Lomefloxacin hydrochloride has broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria. Lomefloxacin hydrochloride has anticancer effects against melanoma. Lomefloxacin hydrochloride can be used in the study of systemic bacterial infections (such as Salmonella typhimurium infections), skin and melanoma       . |  
 
- 
                                        
                                        
                                              
                                    - HY-B1050R
- 
                                        
                                            
                                                | SB-265805S (Standard); LB-20304a (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        DNA/RNA Synthesis
                                                    
                                                        Topoisomerase | Infection |  
                                                | Gemifloxacin (mesylate) (Standard) is the analytical standard of Gemifloxacin (mesylate). This product is intended for research and analytical applications. Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections   . |  
 
- 
                                        
                                        
                                              
                                    - HY-10393
- 
                                        
                                            
                                                | PNU-100592 | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Eperezolid (PNU-100592) is an orally active protein synthesis inhibitor that targets the bacterial 50S ribosomal subunit. Eperezolid competitively binds to a specific site on the ribosomal 50S subunit (overlapping with the binding sites of chloramphenicol (HY-B0239) and lincomycin (HY-117660)) to inhibit the translation initiation stage and exert antibacterial activity. Eperezolid can induce host cell autophagy to enhance the clearance of intracellular mycobacteria, and its MIC90 for Staphylococcus aureus and Enterococcus is 1-4 μg/mL. Eperezolid is mainly used for antibacterial research on infections with Gram-positive bacteria such as methicillin-resistant (HY-121544) Staphylococci and vancomycin-resistant (HY-B0671) Enterococci, as well as infections with intracellular bacteria such as Mycobacterium tuberculosis    . |  
 
- 
                                        
                                        
                                              
                                    - HY-N7101R
- 
                                        
                                            
                                                | U-76,252 (Standard); CS-807 (Standard) | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Penicillin-binding protein (PBP) | Infection |  
                                                | Cefpodoxime Proxetil (Standard) is the analytical standard of Cefpodoxime Proxetil. This product is intended for research and analytical applications. Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases     . |  
 
- 
                                        
                                        
                                              
                                    - HY-N6680R
- 
                                        
                                            
                                                |  | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Virginiamycin S1 (Standard) is the analytical standard of Virginiamycin S1. This product is intended for research and analytical applications. Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections  . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0330B
- 
                                        
                                            
                                                | (-)-Ofloxacin hydrochloride | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        DNA/RNA Synthesis
                                                    
                                                        Topoisomerase
                                                    
                                                        Orthopoxvirus
                                                    
                                                        Apoptosis | Infection
                                                    
                                                        Neurological Disease
                                                    
                                                        Cancer |  
                                                | Levofloxacin hydrochloride is an orally active antibiotic. Levofloxacin inhibits DNA gyrase and topoisomerase IV activity, inducing Apoptosis. Levofloxacin hydrochloride has antibacterial activity against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrochloride exhibits anticancer activity against lung cancer. Levofloxacin hydrochloride has anti-acnegenic, anxiogenic, and analgesic effects. Levofloxacin hydrochloride shortens sleep duration in mice. Levofloxacin hydrochloride can be used in the research of infectious diseases (such as tuberculosis, chronic periodontitis, bacterial infections associated with stable COPD, and BK viremia) and lung cancer          . |  
 
- 
                                        
                                        
                                              
                                    - HY-A0111R
- 
                                        
                                            
                                                | Ro 15-8074 (Standard); Deacetoxycefotaxime (Standard) | Reference Standards
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Penicillin-binding protein (PBP)
                                                    
                                                        Drug Metabolite | Infection |  
                                                | Cefetamet (Standard) is the analytical standard of Cefetamet (HY-A0111). This product is intended for research and analytical applications. Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis     . |  
 
- 
                                        
                                        
                                              
                                    - HY-12770R
- 
                                        
                                            
                                                | Mebeverine metabolite Mebeverine alcohol (Standard) | Reference Standards
                                                    
                                                        Drug Metabolite | Neurological Disease |  
                                                | Mebeverine alcohol (Standard) is an analytical standard for Mebeverine alcohol. This product is intended for research and analytical applications. Eperezolid (PNU-100592) is an orally active protein synthesis inhibitor that targets the bacterial 50S ribosomal subunit. Eperezolid competitively binds to a specific site on the ribosomal 50S subunit (overlapping with the binding sites of Chloramphenicol (HY-B0239) and Lincomycin (HY-117660)) to inhibit the translation initiation stage and exert antibacterial activity. Eperezolid can induce host cell autophagy to enhance the clearance of intracellular mycobacteria, and its MIC90 for Staphylococcus aureus and Enterococcus is 1-4 μg/mL. Eperezolid is mainly used for antibacterial research on infections with Gram-positive bacteria such as methicillin-resistant (HY-121544) Staphylococci and vancomycin-resistant (HY-B0671) Enterococci, as well as infections with intracellular bacteria such as Mycobacterium tuberculosis    . |  
 
- 
                                        
                                        
                                              
                                    - HY-P11064
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | G(IIKK)3I-NH2 is an antimicrobial peptide. G(IIKK)3I-NH2 exhibits potent antibacterial activity against both Gram-negative and Gram-positive bacteria. G(IIKK)3I-NH2 has low toxicity to primary cells and mice, and G(IIKK)3I-NH2 is not easy to induce bacterial resistance. G(IIKK)3I-NH2 can be used in the research of anti-infection agents . |  
 
- 
                                        
                                        
                                              
                                    - HY-W743473
- 
                                        
                                            
                                                | Ro 15-8074-d3;  Deacetoxycefotaxime-d3 | Isotope-Labeled Compounds
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Penicillin-binding protein (PBP)
                                                    
                                                        Drug Metabolite | Infection |  
                                                | Cefetamet-d3 (Ro 15-8074-d3; Deacetoxycefotaxime-d3) is the deuterium labeled Cefetamet (HY-A0111). Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis     . |  
 
- 
                                        
                                        
                                              
                                    - HY-105099
- 
                                        
                                            
                                                | KRM-1648;  ABI-1648 | Antibiotic
                                                    
                                                        DNA/RNA Synthesis
                                                    
                                                        Bacterial | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase . Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml . Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB) . |  
 
- 
                                        
                                        
                                              
                                    - HY-P11085
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | WLBU2 is a engineered cationic antimicrobial peptide (eCAP) that overcomes the environmental sensitivity of natural antimicrobial peptides (AMPs). WLBU2 exhibits rapid bactericidal effect, with the MIC values of ≤ 10 μM against both Gram-negative and Gram-positive bacteria including MRSA, vancomycin-resistant enterococci, K. pneumoniae, E.aerogenes, E. cloacae, Escherichia coli, et, al. WLBU2 prevents P. aeruginosa biofilm growth and retains its activity in an environment rich in mucus, low pH and high salt concentrations without negative effects on human airway epithelial cells. WLBU2 can be used for the studies of cystic fibrosis (CF) and Pseudomonas aeruginosa infections  . |  
 
- 
                                        
                                        
                                              
                                    - HY-69174
- 
                                        
                                            
                                                |  | Bacterial |  |  
                                                | 1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial compound with antibacterial activity against a variety of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). The application potential of 1-Amino-2,5-anhydro-1-deoxy-D-mannitol lies in its ability to effectively combat common drug-resistant bacterial infections. 1-Amino-2,5-anhydro-1-deoxy-D-mannitol may become an emerging antibacterial agent in clinical inhibition. |  
 
- 
                                        
                                        
                                              
                                    - HY-16485
- 
                                        
                                            
                                                | TD-6424 hydrochloride | Antibiotic
                                                    
                                                        Bacterial | Infection |  
                                                | Telavancin hydrochloride is the hydrochloride form of Telavancin (HY-112959). Telavancin hydrochloride is a semisynthetic derivative of vancomycin, and exhibits antibacterial efficacy through inhibition of cell wall synthesis and disruption of cell membrane barrier function. Telavancin hydrochloride is efficient against antibiotic resistant S. aureus strains MRSA, VISA, and hVISA. Telavancin hydrochloride attenuates gram positive bacteria induced complicated skin and skin structure infections (cSSSI) . |  
 
- 
                                        
                                        
                                              
                                    - HY-N7101S
- 
                                        
                                            
                                                | U-76-d7,252-d7;  CS-807-d7 | Isotope-Labeled Compounds
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic
                                                    
                                                        Penicillin-binding protein (PBP) | Infection |  
                                                | Cefpodoxime proxetil-d7 (U-76-d7,252-d7; CS-807-d7) is the deuterium labeled Cefpodoxime Proxetil (HY-N7101). Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases     . |  
 
- 
                                        
                                        
                                              
                                    - HY-B0330BR
- 
                                        
                                            
                                                | (-)-Ofloxacin hydrochloride (Standard) | Reference Standards
                                                    
                                                        Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        DNA/RNA Synthesis
                                                    
                                                        Topoisomerase
                                                    
                                                        Orthopoxvirus
                                                    
                                                        Apoptosis | Infection
                                                    
                                                        Neurological Disease
                                                    
                                                        Cancer |  
                                                | Levofloxacin (hydrochloride) (Standard) is the analytical standard of Levofloxacin hydrochloride (HY-B0330B). This product is intended for research and analytical applications. Levofloxacin hydrochloride is an orally active antibiotic. Levofloxacin inhibits DNA gyrase and topoisomerase IV activity, inducing Apoptosis. Levofloxacin hydrochloride has antibacterial activity against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrochloride exhibits anticancer activity against lung cancer. Levofloxacin hydrochloride has anti-acnegenic, anxiogenic, and analgesic effects. Levofloxacin hydrochloride shortens sleep duration in mice. Levofloxacin hydrochloride can be used in the research of infectious diseases (such as tuberculosis, chronic periodontitis, bacterial infections associated with stable COPD, and BK viremia) and lung cancer          . |  
 
- 
                                        
                                        
                                              
                                    - HY-168729
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | Antibacterial agent 256 (Compound C09) is an inhibitor for type I signal peptidase (SPase I). Antibacterial agent 256 inhibits gram-positive bacteria, that inhibits S. aureus ATCC 29213, E. faecium QF31, E. faecalis SF23-1 and S. suis P1/7, with MIC of 1-16 μg/mL. Antibacterial agent 256 exhibits cytotoxicity in cancer cell HEp-2 and Caco-2 with CC50 of 14.65 μg/mL and 21.93 μg/mL. Antibacterial agent 256 exhibits a hemolytic activity on mouse RBCs, with an HC50 of 13.29 μg/mL. Antibacterial agent 256 ameliorates the MRSA skin infection in mouse model . |  
 
- 
                                        
                                        
                                              
                                    - HY-105099R
- 
                                        
                                            
                                                | KRM-1648 (Standard); ABI-1648 (Standard) | Antibiotic
                                                    
                                                        Reference Standards
                                                    
                                                        DNA/RNA Synthesis
                                                    
                                                        Bacterial | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | Rifalazil (Standard) is the analytical standard of Rifalazil. This product is intended for research and analytical applications. Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase[1]. Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml[3]. Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB)[2]. |  
 
- 
                                        
                                        
                                              
                                    - HY-168204
- 
                                        
                                            
                                                |  | Bacterial
                                                    
                                                        Fungal | Infection |  
                                                | 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid (compound J1) is a potent antimicrobial agent. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid shows anti-gram-positive bacteria and fungi activity. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic acid can be used as antibiotic adjuvants. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic disrupts the bacterial cell membrane, inserts into the DNA, and binds to DNA gyrase. 3-Acetyl-28-N–(3–guanidinobutoxy)-oleanolic reduces microbial count in a mouse MRSA skin infection model and accelerates wound healing . |  
 
- 
                                        
                                        
                                              
                                    - HY-P11027
- 
                                        
                                            
                                                |  | Bacterial
                                                    
                                                        Antibiotic | Infection |  
                                                | Thiazoplanomicin (Compound 1) is a thiazolyl peptide antibiotic. Thiazoplanomicin can be isolated from the leaf-litter actinomycete Actinoplanes sp. MM794L-181F6. Thiazoplanomicin has potent antimicrobial activities against gonococcal strains (especially drug-resistant strains) and Gram-positive bacterium with MICs of 31.2-125 and 0.5-15.6 ng/mL, respectively. Thiazoplanomicin has no antibacterial activity against E.coli. Thiazoplanomicin can be used for bacterial infections research . |  
 
- 
                                        
                                        
                                              
 
            
            
            
            
            
            
            
                
                    
                        
                            | Cat. No. | Product Name | Type | 
                    
                    
                        
                            
                            - 
                                
                                    - HY-B2237A
- 
                                        
                                            
                                                |  | Biochemical Assay Reagents |  
                                                | Lysozyme chloride is a bactericidal enzyme, and it lyses gram-positive bacteria. Lysozyme chloride can also be used for the research of HIV infection and pulmonary emphysema   . |  
 
 
- 
                                
                                    - HY-69174
- 
                                        
                                            
                                                |  | Microbial Culture |  
                                                | 1-Amino-2,5-anhydro-1-deoxy-D-mannitol is a potent antibacterial compound with antibacterial activity against a variety of Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). The application potential of 1-Amino-2,5-anhydro-1-deoxy-D-mannitol lies in its ability to effectively combat common drug-resistant bacterial infections. 1-Amino-2,5-anhydro-1-deoxy-D-mannitol may become an emerging antibacterial agent in clinical inhibition. |  
 
 
 
            
            
            
                
                    
                        
                            | Cat. No. | Product Name | Target | Research Area | 
                    
                    
                        
                            
                            - 
                                
                                    - HY-P2320
- 
                                        
                                            
                                                |  | Bacterial | Infection
                                                    
                                                        Inflammation/Immunology |  
                                                | IDR-1 is an antimicrobial peptide that is active against Gram-positive and Gram-negative bacteria. IDR-1 counters infection by selective modulation of innate immunity without obvious toxicities. IDR-1 has anti-inflammatory and anti-infective properties, enhances the levels of monocyte chemokines, and attenuates pro-inflammatory cytokine release  . |  
 
 
- 
                                
                                    - HY-P10913
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | HYNIC-UBI29-41 is composed of a bifunctional chelator HYNIC and an antimicrobial peptide UBI 29-41. HYNIC-UBI29-41 retains the antibacterial properties of UBI 29-41, and exhibits good affinity to Gram-positive and Gram-negative bacteria. HYNIC-UBI29-41 can be used as an imaging agent for bacterial infection detection in mouse models, when labeled with the radioactive element technetium (99mTc) . |  
 
 
- 
                                
                                    - HY-106882
- 
                                        
                                            
                                                | MDL 62879 | Bacterial
                                                        
                                                    
                                                        
                                                        
                                                            Antibiotic | Infection |  
                                                | GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection  . |  
 
 
- 
                                
                                    - HY-105088A
- 
                                        
                                            
                                                | MSI 78 | Bacterial | Infection |  
                                                | Pexiganan acetate (MSI 78) is the acetate salt form of Pexiganan (HY-105088). Pexiganan acetate is an orally active broad-spectrum antimicrobial peptide, which inhibits 99% gram-positive and Gram-negative aerobic bacteria through disruption of cell membrane/cells permeability. Pexiganan acetate can be used in the research of infections, such as diabetic foot ulcer infections . |  
 
 
- 
                                
                                    - HY-P5724
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | Nv-CATH is an antibacterial peptide of frog origin. Nv-CATH has broad-spectrum antibacterial activity against gram-positive and gram-negative bacteria. Nv-CATH significantly protects mice from fatal infections caused by Staphylococcus aureus. Nv-CATH protects mice from bacterial infection through antimicrobial immunoregulatory duality . |  
 
 
- 
                                
                                    - HY-105048A
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | Omiganan pentahydrochloride is a cationic peptide compound with a broad antibacterial profile. Omiganan pentahydrochloride is capable of inhibiting a variety of bacteria, including yeast, and is active against both gram-positive and gram-negative bacteria. Omiganan pentahydrochloride is able to interact with the bacterial cell membrane, causing the destruction of the cell membrane and the death of the bacteria. Omiganan pentahydrochloride can be used for the study of antimicrobial activity against pathogens commonly associated with catheter-associated infections, including strains with drug-resistant phenotypes . |  
 
 
- 
                                
                                    - HY-P11064
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | G(IIKK)3I-NH2 is an antimicrobial peptide. G(IIKK)3I-NH2 exhibits potent antibacterial activity against both Gram-negative and Gram-positive bacteria. G(IIKK)3I-NH2 has low toxicity to primary cells and mice, and G(IIKK)3I-NH2 is not easy to induce bacterial resistance. G(IIKK)3I-NH2 can be used in the research of anti-infection agents . |  
 
 
- 
                                
                                    - HY-P11085
- 
                                        
                                            
                                                |  | Bacterial | Infection |  
                                                | WLBU2 is a engineered cationic antimicrobial peptide (eCAP) that overcomes the environmental sensitivity of natural antimicrobial peptides (AMPs). WLBU2 exhibits rapid bactericidal effect, with the MIC values of ≤ 10 μM against both Gram-negative and Gram-positive bacteria including MRSA, vancomycin-resistant enterococci, K. pneumoniae, E.aerogenes, E. cloacae, Escherichia coli, et, al. WLBU2 prevents P. aeruginosa biofilm growth and retains its activity in an environment rich in mucus, low pH and high salt concentrations without negative effects on human airway epithelial cells. WLBU2 can be used for the studies of cystic fibrosis (CF) and Pseudomonas aeruginosa infections  . |  
 
 
- 
                                
                                    - HY-P11027
- 
                                        
                                            
                                                |  | Bacterial
                                                        
                                                    
                                                        
                                                        
                                                            Antibiotic | Infection |  
                                                | Thiazoplanomicin (Compound 1) is a thiazolyl peptide antibiotic. Thiazoplanomicin can be isolated from the leaf-litter actinomycete Actinoplanes sp. MM794L-181F6. Thiazoplanomicin has potent antimicrobial activities against gonococcal strains (especially drug-resistant strains) and Gram-positive bacterium with MICs of 31.2-125 and 0.5-15.6 ng/mL, respectively. Thiazoplanomicin has no antibacterial activity against E.coli. Thiazoplanomicin can be used for bacterial infections research . |  
 
 
 
            
            
            
            
            
            
            
                
                    
                        
                            | Cat. No. | Product Name | Category | Target | Chemical Structure | 
                    
                    
                        
                            
                            - 
                                
                                    - HY-117660
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B2237
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B1150
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N15551
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-117660R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-W923644
- 
                                        
                                            
                                                | Aegelinol; (-)-Smyrinol | Structural Classification
                                                            
                                                        
                                                            
                                                            
                                                                Scutellaria barbataD. Don
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Coumarins
                                                            
                                                        
                                                            
                                                            
                                                                Phenylpropanoids
                                                            
                                                        
                                                            
                                                            
                                                                Umbelliferae
                                                            
                                                        
                                                            
                                                            
                                                                Plants 
                                                        
                                                     | Bacterial |  
                                                | (-)-Decursinol (Aegelinol; (-)-Smyrinol) is a natural pyranocoumarin compound tant can be isolated from the roots of Apiaceae plants such as Ferulago campestris. (-)-Decursinol inhibits both Gram-positive bacteria (Staphylococcus aureus ATCC 13709, Enterococcus faecalis ATCC 14428) and Gram-negative bacteria (Salmonella typhii ATCC 19430, Enterobacter cloacae ATCC 10699, Enterobacter aerogenes ATCC 13048) with minimum inhibitory concentrations (MIC) ranging from 16 to 64 μg/mL. (-)-Decursinol possesses antioxidant activity. (-)-Decursinol can be used for the study of bacterial infections . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N14202
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N14201
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N14203
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N14200
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-125608
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N15095
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0474
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-A0107
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B1150R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N14217
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0958
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-A0107R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B1369
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-105088A
- 
                                        
                                            
                                                | MSI 78 | Natural Products
                                                            
                                                            
                                                        
                                                            
                                                            
                                                                Animals
                                                            
                                                        
                                                            
                                                            
                                                                Source classification 
                                                        
                                                     | Bacterial |  
                                                | Pexiganan acetate (MSI 78) is the acetate salt form of Pexiganan (HY-105088). Pexiganan acetate is an orally active broad-spectrum antimicrobial peptide, which inhibits 99% gram-positive and Gram-negative aerobic bacteria through disruption of cell membrane/cells permeability. Pexiganan acetate can be used in the research of infections, such as diabetic foot ulcer infections . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0958R
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N12496
- 
                                        
                                            
                                                |  | Natural Products
                                                            
                                                            
                                                        
                                                            
                                                            
                                                                Magnoliaceae
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Plants 
                                                        
                                                     | Fungal
                                                    
                                                        Bacterial |  
                                                | Di-O-methylhonokiol is a natural phenolic compound that can be isolated from magnolia flowers. Di-O-methylhonokiol has significant antibacterial activity against Gram-positive bacteria, acid-fast bacilli, and yeast-like and filamentous fungi. Di-O-methylhonokiol can be used in the study of fungal infections . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-A0097
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-A0097A
- 
                                        
                                            
                                                | Antibiotic MDL-507 sodium; MDL-507 sodium | Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Phenols
                                                            
                                                        
                                                            
                                                            
                                                                Polyphenols
                                                            
                                                        
                                                            
                                                            
                                                                Endogenous metabolite 
                                                        
                                                     | Antibiotic
                                                    
                                                        HIV
                                                    
                                                        SARS-CoV |  
                                                | Teicoplanin sodium is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin sodium shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity  . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B1369R
- 
                                        
                                            
                                                | N-Formimidoyl thienamycin monohydrate (Standard); MK0787 monohydrate (Standard) | Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Antibiotics
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Antibacterial
                                                            
                                                        
                                                            
                                                            
                                                                Disease Research
                                                            
                                                        
                                                            
                                                            
                                                                Other Antibiotics 
                                                        
                                                     | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic |  
                                                | Imipenem (monohydrate) (Standard) is the analytical standard of Imipenem (monohydrate). This product is intended for research and analytical applications. Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections   . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N7123
- 
                                        
                                            
                                                | Sulphacetamide | Infection
                                                            
                                                        
                                                            
                                                            
                                                                Classification of Application Fields
                                                            
                                                        
                                                            
                                                            
                                                                Disease Research Fields 
                                                        
                                                     | Antibiotic
                                                    
                                                        Bacterial
                                                    
                                                        Fungal |  
                                                | Sulfacetamide (Sulphacetamide) is a sulfonamide antibiotic. Sulfacetamide has antifungal and antibacterial activities. Sulfacetamide is employed as a topical formulation in various ophthalmic, dermatological, and hair solutions against bacterial infections, acne and scalp conditions. Sulfacetamide targets bacterial folic acid synthesis and is effective against various gram-positive and gram-negative bacteria. Sulfacetamide inhibits the synthesis of both dihydro-folic acid and para-aminobenzoic acid. Sulfacetamide can be used for the study of ocular infections  . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N7224
- 
                                        
                                            
                                                | SF-1854 | Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Ketones, Aldehydes, Acids
                                                            
                                                        
                                                            
                                                            
                                                                Source classification 
                                                        
                                                     | Bacterial
                                                    
                                                        Antibiotic |  
                                                | N-Formylfortimicin A (SF-1854) is an aminoglycoside antibiotic with broad-spectrum antibacterial activity. It primarily acts on bacterial ribosomes to inhibit protein synthesis and exhibits notable inhibitory effects against various Gram-positive and Gram-negative bacteria (e.g., E. coli with a MIC of 12.5-50 μg/mL), making it a potential candidate for research on bacterial infection-related diseases . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N6680
- 
                                        
                                    
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N6680R
- 
                                        
                                            
                                                |  | Microorganisms
                                                            
                                                        
                                                            
                                                            
                                                                Macrolide Antibiotics
                                                            
                                                        
                                                            
                                                            
                                                                Antibiotics
                                                            
                                                        
                                                            
                                                            
                                                                Source classification
                                                            
                                                        
                                                            
                                                            
                                                                Antibacterial
                                                            
                                                        
                                                            
                                                            
                                                                Disease Research 
                                                        
                                                     | Reference Standards
                                                    
                                                        Bacterial
                                                    
                                                        Antibiotic |  
                                                | Virginiamycin S1 (Standard) is the analytical standard of Virginiamycin S1. This product is intended for research and analytical applications. Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation. Virginiamycin S1 belongs to the type B compounds in the streptogramin family and is produced by Streptomyces virginiae, shows a strong bactericidal activity against a wide range of Gram-positive bacteria. Virginiamycin S1 together with virginiamycin M1 is more effective in treat multidrug-resistant bacterial infections  . |  
 
- 
                                        
                                        
                                              
 
 
            
            
            
            
            
                
                    
                        
                            | Cat. No. | Product Name | Chemical Structure | 
                    
                    
                        
                            
                            - 
                                
                                    - HY-B0510S
- 
                                        
                                            
                                                |  |  
                                                | Trimethoprim-d9 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment   . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0510S2
- 
                                        
                                            
                                                |  |  
                                                | Trimethoprim-d3is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment   . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-17395S
- 
                                        
                                            
                                                |  |  
                                                | Terbinafine-d3 hydrochloride is the deuterium labeled Terbinafine hydrochloride. Terbinafine hydrochloride (TDT 067 hydrochloride) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM  . Terbinafine hydrochloride also antibacterial activity against certain Gram-positive and Gram-negative bacteria . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B1002S
- 
                                        
                                            
                                                |  |  
                                                | Oxolinic acid-d5 is the deuterium labeled Oxolinic acid. Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice   . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B1282S
- 
                                        
                                            
                                                |  |  
                                                | Sulfaquinoxaline-d4 is the deuterium labeled Sulfaquinoxaline. Sulfaquinoxaline is an antimicrobial for veterinary use, with activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Sulfaquinoxaline is used to prevent coccidiosis and bacterial infections  . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-A0107S2
- 
                                        
                                            
                                                |  |  
                                                | Tetracycline-d6-1 is deuterated labeled Tetracycline (HY-A0107). Tetracycline is a broad-spectrum antibiotic with oral activity. Tetracycline exhibits activity against a wide range of bacteria including gram-positive, gram-negative bacteria, chlamydiae, mycoplasmas and rickettsiae. Tetracycline can be used for the research of infections . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0395S
- 
                                        
                                            
                                                |  |  
                                                | Sitafloxacin-d4 (DU6859a-d4) is deuterium labeled Sitafloxacin. Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection  . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0126S
- 
                                        
                                            
                                                |  |  
                                                | Marbofloxacin-d8 is the deuterium labeled Marbofloxacin. Marbofloxacin is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma   . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0126AS
- 
                                        
                                            
                                                |  |  
                                                | Marbofloxacin-d8 (hydrochloride) is deuterium labeled Marbofloxacin (hydrochloride). Marbofloxacin hydrochloride is a third generation fluoroquinolone and orally active antimicrobial agent, which has a broad spectrum bactericidal activity and good efficacy. Marbofloxacin hydrochloride can be used for the research of infections by Gram-positive and Gram-negative bacteria and Mycoplasma    . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-17395AS
- 
                                        
                                            
                                                |  |  
                                                | Terbinafine-d7 is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM  . Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0213S
- 
                                        
                                            
                                                |  |  
                                                | Sulfameter-d4 (Sulfametoxydiazine-d4) is the deuterium labeled Sulfameter (HY-B0213) . Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0724BS
- 
                                        
                                            
                                                |  |  
                                                | Pazufloxacin-d4 is deuterium labeled Pazufloxacin (HY-B0724B). Pazufloxacin is an orally active fluoroquinolone antimicrobial agent. Pazufloxacin inhibits DNA gyrase with IC50 values of 0.88 μg/mL (E. coli) and 1.9 μg/mL (P. aeruginosa). Pazufloxacin exhibits broad-spectrum antimicrobial activity, with MIC90 values ranging from 0.025 to 100 μg/mL against Gram-positive and Gram-negative bacteria, non-fermenting bacteria, Legionella spp., and anaerobic bacteria. Pazufloxacin is indicated for research on systemic infections, lung infections, urinary tract infections, and Legionella pneumonia      . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0510S3
- 
                                        
                                            
                                                |  |  
                                                | Trimethoprim- 13C3 is the deuterium labeled Trimethoprim (HY-B0510) . Trimethoprim is a bacteriostatic antibiotic and an orally active dihydrofolate reductase inhibitor. Trimethoprim is active against a wide range of Gram-positive and Gram-negative aerobic bacteria. Trimethoprim has the potential for the research of urinary tract infections, Shigellosis and Pneumocystis pneumonia. Trimethoprim can inhibit infection of Influenza A virus in chick embryo when combinated with zinc    . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-10394S1
- 
                                        
                                            
                                                |  |  
                                                | PNU-100766-d8 is deuterated labeled Linezolid (HY-10394). Linezolid (PNU-100766) is the first member of the class of oxazolidinone synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. Linezolid is used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics   . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0213S1
- 
                                        
                                            
                                                |  |  
                                                | Sulfameter- 13C6 (Sulfametoxydiazine- 13C6) is the  13C6 labeled Sulfameter (HY-B0213). Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections   . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-B0136S
- 
                                        
                                            
                                                |  |  
                                                | Cefdinir- 13C, 15N2 (FK-482- 13C, 15N2) is  13C and  15N labeled Cefdinir. Cefdinir (FK-482) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for infections caused by several Gram-negative and Gram-positive bacteria. Cefdinir can be used for the research of common bacterial infections of the ear, sinus, throat, and skin  . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-W743473
- 
                                        
                                            
                                                |  |  
                                                | Cefetamet-d3 (Ro 15-8074-d3; Deacetoxycefotaxime-d3) is the deuterium labeled Cefetamet (HY-A0111). Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis     . |  
 
- 
                                        
                                        
                                              
 
- 
                                
                                    - HY-N7101S
- 
                                        
                                            
                                                |  |  
                                                | Cefpodoxime proxetil-d7 (U-76-d7,252-d7; CS-807-d7) is the deuterium labeled Cefpodoxime Proxetil (HY-N7101). Cefpodoxime Proxetil is an orally active broad spectrum third-generation cephalosporin with potent antibacterial activity against both Gram-positive and Gram-negative bacteria including staphylococci, streptococci, Haemophilus influenzae, Neisseria gonorrhoeae, Escherichia coli, Klebsiella pnuemoniae, Citrobacter spp, and Proteus spp. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis. Cefpodoxime Proxetil can be used against skin structure infections, acute otitis media, pharyngitis, tonsillitis, upper respiratory tract infection, urinary tract infections and sexually transmitted diseases     . |  
 
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