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Decoy substrate

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W013724
    Inosine-5'-diphosphoric acid disodium

    		c-Myc Apoptosis Cancer
    Inosine-5'-diphosphoric acid disodium (Inosine 5′-diphosphate disodium) is a decoy substrate of NM23-H2. Inosine-5'-diphosphoric acid disodium has a superior bond capacity on GDP-binding pocket of NM23-H2 (KD: 5.0 μM). Inosine-5'-diphosphoric acid disodium abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphoric acid disodium can be used for cancers like Burkitt's lymphoma research .
    Inosine-5'-diphosphoric acid disodium

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