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D-glucuronic acid

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30

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10

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3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6612
    D-Glucuronic acid
    1 Publications Verification

    Endogenous Metabolite Toll-like Receptor (TLR) Metabolic Disease Inflammation/Immunology Cancer
    D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity .
    D-Glucuronic acid
  • HY-N6612A

    Endogenous Metabolite Metabolic Disease
    D-Glucuronic acid sodium salt monohydrate is an endogenous metabolite.
    D-Glucuronic acid sodium salt monohydrate
  • HY-N6612R

    Reference Standards Endogenous Metabolite Toll-like Receptor (TLR) Metabolic Disease Inflammation/Immunology Cancer
    D-Glucuronic acid (Standard) is the analytical standard of D-Glucuronic acid. This product is intended for research and analytical applications. D-Glucuronic acid is a major component of many anti-inflammatory proteoglycans, which can promote embryonic development and inhibit cell aggregation. After being metabolized into ethyl glucuronide (HY-113093), D-Glucuronic acid activates Toll-like receptor 4 (TLR4), causing pain. D-Glucuronic acid and its derivative glucurono-lactone can serve as liver detoxifiers for human health prevention, and its derivatives also possess anti-tumor activity .
    D-Glucuronic acid (Standard)
  • HY-N6612S

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    D-Glucuronic acid sodium monohydrate- 13C6 is the 13C-labeled D-Glucuronic acid sodium salt monohydrate (HY-N6612A). D-Glucuronic acid sodium salt monohydrate is an endogenous metabolite.
    D-Glucuronic acid sodium monohydrate-13C6
  • HY-41982
    D-Glucuronic acid lactone
    1 Publications Verification

    D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone

    Endogenous Metabolite Drug Derivative Cardiovascular Disease Metabolic Disease
    D-Glucuronic acid lactone (D-Glucurono-6,3-lactone) is an endogenous metabolite, which is a glucuronic acid derivative. D-Glucuronic acid lactone can be used as starting regents in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, requirement for the preparation of 1-O-acyl glucuronide of the anti-inflammatory agent ML-3000 (HY-B1452), synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides. D-Glucuronic acid lactone is promising for research of reversible cerebral vasoconstriction syndrome (RCVS) .
    D-Glucuronic acid lactone
  • HY-128749

    Potassium D-glucarate

    Endogenous Metabolite Apoptosis Metabolic Disease Inflammation/Immunology Cancer
    D-Glucaric acid potassium (Potassium D-glucarate) is an orally active end product of the D-glucuronic acid pathway in mammals. D-Glucaric acid potassium is present in a variety of fruits and vegetables. D-Glucaric acid potassium has cholesterol-lowering and anti-tumor activities. D-Glucaric acid potassium can inhibit tumor cell proliferation and inflammation, and induce apoptosis .
    D-Glucaric acid potassium
  • HY-137134

    Biochemical Assay Reagents Others
    D-Glucuronic acid,2-propen-1-yl ester is a biochemical assay reagent.
    D-Glucuronic acid,2-propen-1-yl ester
  • HY-41982R

    D-Glucurono-6,3-lactone (Standard); D-Glucurono-γ-lactone (Standard); D-Glucuronolactone (Standard); Dicurone (Standard); Glucoxy (Standard); Glucurolactone (Standard); Glucurone (Standard)

    Reference Standards Endogenous Metabolite Metabolic Disease
    D-Glucuronic acid lactone (Standard) is the analytical standard of D-Glucuronic acid lactone. This product is intended for research and analytical applications. D-Glucuronic acid lactone is an endogenous metabolite.
    D-Glucuronic acid lactone (Standard)
  • HY-W699702

    Biochemical Assay Reagents Others
    D-Glucuronic acid,methyl ester,2,3,4-tribenzoate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    D-Glucuronic acid,methyl ester,2,3,4-tribenzoate
  • HY-W145597

    Drug Derivative Others
    D-Glucuronamide is the derivate of D-glucuronic acid .
    D-Glucuronamide
  • HY-E70035

    Endogenous Metabolite Metabolic Disease
    Glucuronokinase (AtGlcAK) is a member of the GHMP-kinase. Glucuronokinase (AtGlcAK) shows unique substrate specificity for D-glucuronic acid with a Km value of 0.7 mM. Glucuronokinase (AtGlcAK) catalyzes D-glucuronic acid and ATP to produce D-glucuronic acid-1-phosphate and ADP .
    Glucuronokinase (AtGlcAK)
  • HY-W008125

    Acetobromo-alpha-D-glucuronic acid methyl ester, 98%

    Biochemical Assay Reagents Drug Intermediate Cardiovascular Disease
    Acetobromo-α-D-glucuronic acid methyl ester, 98% is an intermediate. Acetobromo-α-D-glucuronic acid methyl ester, 98% can be used to synthesize HMR1098-S-Glucuronide Methyl Ester. HMR1098 is a novel KATP blocker that is metabolized to S-glucuronide in rat and dog bile. Acetobromo-α-D-glucuronic acid methyl ester, 98% can be used in the research of sudden cardiac death .
    Acetobromo-α-D-glucuronic acid methyl ester, 98%
  • HY-153179

    Drug-Linker Conjugates for ADC Topoisomerase Cancer
    Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for Antibody-Drug Conjugates (ADCs) synthesis. Mal-Gly-PAB-Exatecan-D-glucuronic acid can be used for research of tumor research and diagnosis .
    Mal-Gly-PAB-Exatecan-D-glucuronic acid
  • HY-W357152

    Biochemical Assay Reagents Others
    2-Naphthyl-β-D-glucuronic acid sodium can be used in glycobiology research.
    2-Naphthyl-β-D-glucuronic acid sodium
  • HY-160885A

    ADC Payload Cancer
    NH2-Gly-PAB-Exatecan-D-glucuronic acid formic (Compound 8) is the formic salt form of H2N-Gly-PAB-Exatecan-D-glucuronic acid. H2N-Gly-PAB-Exatecan-D-glucuronic acid formic is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179) .
    NH2-Gly-PAB-Exatecan-D-glucuronic acid formic
  • HY-160885

    ADC Payload Others
    NH2-Gly-PAB-Exatecan-D-glucuronic acid (Compound 8) is an intermediate, which reacts with NHS group to form drug-linker conjugate for ADC, Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179) .
    NH2-Gly-PAB-Exatecan-D-glucuronic acid
  • HY-N9412

    Others Others
    4-O-Methyl-D-glucuronic acid is a kind of hemicellulose that can be isolated from the holocellulose of the Ganpi bast fibers .
    4-O-Methyl-D-glucuronic acid
  • HY-W008125S

    Methyl acetobromo-α-D-glucuronate-13C6 methyl ester

    Isotope-Labeled Compounds Biochemical Assay Reagents Drug Intermediate Cardiovascular Disease
    Acetobromo-a-D-glucuronic acid- 13C6 methyl ester (Methyl acetobromo-α-D-glucuronate- 13C6 methyl ester) is 13C labeled Acetobromo-α-D-glucuronic acid methyl ester, 98% (HY-W008125). Acetobromo-α-D-glucuronic acid methyl ester, 98% is an intermediate. Acetobromo-α-D-glucuronic acid methyl ester, 98% can be used to synthesize HMR1098-S-Glucuronide Methyl Ester. HMR1098 is a novel KATP blocker that is metabolized to S-glucuronide in rat and dog bile. Acetobromo-α-D-glucuronic acid methyl ester, 98% can be used in the research of sudden cardiac death .
    Acetobromo-a-D-glucuronic acid-13C6 methyl ester
  • HY-125954

    UDP-α-D-glucuronic acid

    Endogenous Metabolite Metabolic Disease
    Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .
    Uridine diphosphate glucuronic acid
  • HY-W048546

    Methyl-(2,3,4-tri-O-acetyl-a-D-glucopyranosyl)uronate

    Biochemical Assay Reagents
    2,3,4-Tri-O-acetyl-α-D-glucuronic acid methyl ester is a Biochemical Assay Reagent, and can be used for chemical synthesis .
    2,3,4-Tri-O-acetyl-α-D-glucuronic acid methyl ester
  • HY-W403047

    Biochemical Assay Reagents Others
    Methyl 2,3,4-Tri-O-benzyl-α-D-glucuronic Acid, Benzyl Ester is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    Methyl 2,3,4-Tri-O-benzyl-α-D-glucuronic Acid, Benzyl Ester
  • HY-W794390

    Biochemical Assay Reagents Others
    2,3,4-Tri-O-benzoyl-α-D-glucuronic acid methyl ester,trichloroacetimidate is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    2,3,4-Tri-O-benzoyl-α-D-glucuronic acid methyl ester,trichloroacetimidate
  • HY-W412723

    β-D-Glucopyranuronic acid tetraacetate

    Biochemical Assay Reagents
    1,2,3, 4-tetra-o-acetyl-β-d-glucuronic acid (β-D-Glucopyranuronic acid tetraacetate) is a class of biochemical reagents used in the study of glycobiology. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It deals with carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. The field is closely related to basic research, biomedicine and biotechnology .
    1,2,3,4-Tetra-O-acetyl-β-D-glucuronic acid
  • HY-W039890

    Biochemical Assay Reagents Others
    1-(2,2,2-Trifluoro-N-phenylacetimidate)-2,3,4-tri-?O-acetyl-D-glucuronic acid methyl ester is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .
    1-(2,2,2-Trifluoro-N-phenylacetimidate)-2,3,4-tri-​O-acetyl-D-glucuronic acid methyl ester
  • HY-125954S

    UDP-α-D-glucuronic acid-13C,15N2

    Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    Uridine diphosphate glucuronic acid- 13C, 15N2 (UDP-α-D-glucuronic acid- 13C, 15N2) is the 13C- and 15N-labeled Uridine diphosphate glucuronic acid (HY-125954). Uridine diphosphate glucuronic acid (UDP-α-D-glucuronic acid) is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .
    Uridine diphosphate glucuronic acid-13C,15N2
  • HY-128749AR

    Calcium D-glucarate tetrahydrate (Standard)

    Endogenous Metabolite Reference Standards Apoptosis Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    D-Glucaric acid tetrahydrate (Standard) (Calcium D-glucarate tetrahydrate (Standard)) is the analytical standard of D-Glucaric acid tetrahydrate (HY-128749A). This product is intended for research and analytical applications. D-Glucaric acid tetrahydrate (Calcium D-glucarate tetrahydrate) is an orally active end product of the mammalian D-glucuronidation pathway. D-Glucaric acid tetrahydrate is found in a variety of fruits and vegetables. D-Glucaric acid tetrahydrate induces cell Apoptosis. D-Glucaric acid tetrahydrate reduces the expression of hippocampal myelin-related genes (Mbp, Plp1). D-Glucaric acid tetrahydrate has cholesterol-lowering and anti-tumor activities. D-Glucaric acid tetrahydrate can be used in the research of neurological diseases .
    D-Glucaric acid tetrahydrate (Standard)
  • HY-128749A

    Calcium D-glucarate tetrahydrate

    Endogenous Metabolite Apoptosis Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    D-Glucaric acid tetrahydrate (Calcium D-glucarate tetrahydrate) is an orally active end product of the mammalian D-glucuronidation pathway. D-Glucaric acid tetrahydrate is found in a variety of fruits and vegetables. D-Glucaric acid tetrahydrate induces cell Apoptosis. D-Glucaric acid tetrahydrate reduces the expression of hippocampal myelin-related genes (Mbp, Plp1). D-Glucaric acid tetrahydrate has cholesterol-lowering and anti-tumor activities. D-Glucaric acid tetrahydrate can be used in the research of neurological diseases .
    D-Glucaric acid tetrahydrate
  • HY-125954A

    UDP-α-D-glucuronic acid ammonium

    Endogenous Metabolite Metabolic Disease
    Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum .
    Uridine diphosphate glucuronic acid ammonium
  • HY-D1578

    Fluorescent Dye β-glucuronidase Others
    C12FDGlcU is a lipophilic analog of fluorescein di-β-D-glucuronic acid. C12FDGlcU can be useful for the detection of β-glucuronidase (GUS) gene expression. C12FDGlcU can enter the cells and then be cleaved by β-glucuronidase, generating the yellow-colored, green-fluorescent fluorescein (Abs/Em of the reaction product: 495/518 nm) .
    C12FDGlcU
  • HY-177434

    Precem-TcT; M 9140

    Antibody-Drug Conjugates (ADCs) Transmembrane Glycoprotein Topoisomerase Cancer
    Precemtabart tocentecan (Precem-TcT; M 9140) is an anti-CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5) antibody-drug conjugate (ADC). Precemtabart tocentecan consists of a tumor-specific anti-CEACAM5 monoclonal antibody Precemtabart (HY-P990940), a highly hydrophilic and stable cleavable β-glucuronide linker, and a topoisomerase 1 inhibitor payload Exatecan (HY-13631), and the drug-linker conjugate for ADC is Mal-Gly-PAB-Exatecan-D-glucuronic acid (HY-153179). Precemtabart tocentecan inhibits the growth of CEACAM5-positive cancer cells. Precemtabart tocentecan exhibits significant antitumor activity in CEACAM5-expressing xenograft models. Precemtabart tocentecan can be used for the study of CEACAM5-expressing advanced solid tumors, especially mCRC .
    Precemtabart tocentecan

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