Search Result
Results for "
Chloromethyl
" in MedChemExpress (MCE) Product Catalog:
3
Biochemical Assay Reagents
5
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-Z2475
-
|
Chloromethyl Propyl Carbonate
|
Drug Intermediate
|
Others
|
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Tenofovir Impurity 54 (Chloromethyl Propyl Carbonate) is an impurity of Tenofovir (HY-13910).
|
-
-
- HY-43384
-
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Tenofovir Impurity 66
|
Drug Intermediate
|
Others
|
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Chloromethyl methyl carbonate (Tenofovir Impurity 66) is a drug intermediate for synthesis of various active compounds.
|
-
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- HY-76779
-
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Drug Derivative
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Cancer
|
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4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII .
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-
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- HY-W013510
-
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Biochemical Assay Reagents
|
Others
|
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2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-52102
-
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Drug Intermediate
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Others
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2-(Chloromethyl)pyrimidine hydrochloride is a synthetic intermediate useful for pharmaceutical synthesis.
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-
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- HY-W015577R
-
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Reference Standards
|
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Chloromethyl isopropyl carbonate (Standard) is the analytical standard of Chloromethyl isopropyl carbonate. This product is intended for research and analytical applications.
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-
-
- HY-W010311R
-
|
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Reference Standards
|
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1-(Chloromethyl)-4-methylbenzene (Standard) is the analytical standard of 1-(Chloromethyl)-4-methylbenzene. This product is intended for research and analytical applications.
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-
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- HY-I0482R
-
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Reference Standards
|
|
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2-(Chloromethyl)-4-methylquinazoline (Standard) is the analytical standard of 2-(Chloromethyl)-4-methylquinazoline. This product is intended for research and analytical applications.
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-
-
- HY-W704178
-
-
-
- HY-156723
-
|
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Topoisomerase
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Cancer
|
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9-Chloromethyl-10-hydroxy-11-F-Camptothecin is a novel camptothecin derivatives. 9-Chloromethyl-10-hydroxy-11-F-Camptothecin is a DNA topoisomerase I (Topo I) inhibitor, can be used in anticancer research .
|
-
-
- HY-W742282
-
-
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- HY-W016753R
-
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Reference Standards
|
|
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1,3-Bis(chloromethyl)benzene (Standard) is the analytical standard of 1,3-Bis(chloromethyl)benzene. This product is intended for research and analytical applications.
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-
-
- HY-42850
-
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Drug Intermediate
|
Others
|
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5-Chloromethyl-1-propyl-1H-imidazole hydrochloride is a drug intermediate for synthesis of various active compounds.
|
-
-
- HY-W540356
-
-
-
- HY-W007502
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-
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- HY-W040762R
-
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Reference Standards
|
|
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2,4-Dichloro-1-(chloromethyl)benzene (Standard) is the analytical standard of 2,4-Dichloro-1-(chloromethyl)benzene. This product is intended for research and analytical applications.
|
-
-
- HY-W319189
-
-
-
- HY-137038
-
|
TLCK hydrochloride
|
Caspase
Ser/Thr Protease
|
Cancer
|
|
N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride (TLCK hydrochloride) is an irreversible inhibitor for serine protease, which inhibits trypsin and trypsin-like protease by alkylating histidine residues in their active site. N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride inhibits caspase-3, caspase-6 and caspase-7, with IC50s of 12.0, 54.5 and 19.3 μM, respectively. N-alpha-Tosyl-Lys chloromethyl ketone hydrochloride induces apoptosis in cell HL-60, and inhibits the decrease in mitochondrial transmembrane potential during apoptosis .
|
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-
- HY-I0167
-
|
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Drug Intermediate
|
Others
|
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1-(2-(4-(Chloromethyl)phenoxy)ethyl)azepane hydrochloride is a drug intermediate for synthesis of various active compounds.
|
-
-
- HY-W587507
-
|
1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate
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Others
|
Metabolic Disease
|
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1,2-Dilauroyl-3-chloropropanediol (1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate) is an ester product.
|
-
-
- HY-23565
-
|
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Drug Intermediate
|
Others
|
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(R)-1,4-Dibenzyl-2-(chloromethyl)piperazine is a drug intermediate for synthesis of various active compounds.
|
-
-
- HY-W711764
-
-
-
- HY-112716
-
|
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Amino Acid Derivatives
|
Cancer
|
|
N-alpha-Tosyl-L-lysine chloromethyl ketone (TLCK), a trypsin like protease inhibitor, sensitizes HeLa cells to Fas-mediated cell death.
|
-
-
- HY-W654074
-
|
1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate-d5
|
Isotope-Labeled Compounds
Biochemical Assay Reagents
|
Metabolic Disease
|
|
1,2-Dilauroyl-3-chloropropanediol-d5 (1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate-d5) is the deuterium labeled 1,2-Dilauroyl-3-chloropropanediol (HY-W587507). 1,2-Dilauroyl-3-chloropropanediol (1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate) is an ester product.
|
-
-
- HY-P10095
-
-
-
- HY-P10095A
-
|
D-Val-Phe-Lys Chloromethyl ketone diTFA
|
Ser/Thr Protease
|
Metabolic Disease
|
|
D-Val-Phe-Lys-CMK (D-Val-Phe-Lys Chloromethyl ketone) diTFA can inhibit plasmin activity .
|
-
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- HY-D1278
-
|
|
Fluorescent Dye
|
Others
|
|
4-(5)-(((4-ChloroMethyl)Benzoyl)AMino)TetraMethylrhodaMine is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
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- HY-D1462
-
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Fluorescent Dye
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Others
|
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CellTracker Blue CMAC is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels .
|
-
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- HY-DY1041
-
|
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Fluorescent Dye
|
Others
|
CellTracker Blue CMAC (solution) is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels . Solution Concentration: 10 mM
|
-
-
- HY-124379
-
TPCK
1 Publications Verification
L-1-Tosylamido-2-phenylethyl Chloromethyl ketone; L-TPCK
|
Ser/Thr Protease
HPV
Apoptosis
PDK-1
|
Infection
Neurological Disease
Inflammation/Immunology
Cancer
|
|
TPCK (L-1-Tosylamido-2-phenylethyl chloromethyl ketone; L-TPCK) is an effective serine protease inhibitor and also a blocker of the PDK1/Akt pathway. TPCK can modify the E7 protein in actively keratinocyte cells. TPCK can induce cellular apoptosis, suppress tumor growth, reduce hypoxic-ischemic brain injury in rat pups, and affect vascular permeability in inflamed rats .
|
-
-
- HY-Z2475R
-
|
|
Reference Standards
|
|
|
chloromethyl propyl carbonate (Tenofovir Impurity) (Standard) is the analytical standard of chloromethyl propyl carbonate (Tenofovir Impurity). This product is intended for research and analytical applications.
|
-
-
- HY-P10828
-
|
|
Virus Protease
|
Infection
Inflammation/Immunology
|
|
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .
|
-
-
- HY-122542A
-
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Pebac; D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone; D-Phe-Pro-Arg-CH2Cl
|
Thrombin
PAI-1
|
Cardiovascular Disease
|
|
PPACK dihydrochloride is potent, selective and irreversible thrombin inhibitor. PPACK dihydrochloride can be used an alternative anticoagulant to lithium heparin (LiHep) for blood gas and whole-blood electrolyte analyses. PPACK dihydrochloride is also a plasminogen activator (rt-PA) inhibitor. PPACK dihydrochloride can inhibit the binding of rt-PA to plasma protease inhibitors .
|
-
-
- HY-129047C
-
|
|
Biochemical Assay Reagents
Influenza Virus
|
Infection
|
|
TPCK-treated Trypsin is a trypsin whose activity is inhibited by tosyl phenylalanyl chloromethyl ketone. TPCK-treated Trypsin reduces autolysis and nonspecific proteolysis during experiments, exhibits stability in storage and handling. TPCK-treated trypsin can be used in proteomics research . TPCK-treated Trypsin renders the virus hemagglutinin active, which allows multicycle replication of the virus. TPCK-treated Trypsin can be used for the study of influenza virus .
|
-
-
- HY-P1108A
-
|
|
CFTR
|
Others
|
|
Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC50 values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B TFA antagonizes CRF2-mediated inhibition of gastric emptying .
|
-
-
- HY-P1108
-
|
|
CFTR
|
Others
|
|
Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC50 values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B antagonizes CRF2-mediated inhibition of gastric emptying .
|
-
-
- HY-P2592
-
-
-
- HY-P10579
-
123B9
1 Publications Verification
|
Ephrin Receptor
|
Cancer
|
|
123B9, a tumor-homing agent, is a potent and selective EphA2 agonist with a Kd value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. 123B9 does not appreciably inhibit the ligand binding domains of the most closely related EphA3 and EphA4 receptors .
|
-
-
- HY-P4521
-
|
|
MMP
|
Others
|
|
Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt is a MMP12 substrate, and can be used to detect MMP12 enzyme activity .
|
-
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- HY-P3066
-
|
d(CH2)5Tyr(Et)VAVP
|
Vasopressin Receptor
|
Metabolic Disease
|
|
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
|
-
-
- HY-125628
-
|
|
Endogenous Metabolite
|
Infection
|
|
Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .
|
-
-
- HY-P10272
-
|
PTG-300
|
Ferroportin
|
Others
|
|
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .
|
-
-
- HY-A0248A
-
|
|
Bacterial
|
Infection
|
|
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
|
-
-
- HY-A0248AS
-
|
|
Isotope-Labeled Compounds
Bacterial
|
Infection
|
|
Polymyxin B1-d7 TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
|
-
-
- HY-P10563
-
|
BHV-1100
|
CD38
|
Cancer
|
|
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D1462
-
|
|
Fluorescent Dye
|
|
CellTracker Blue CMAC is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels .
|
-
- HY-D1278
-
|
|
Fluorescent Dye
|
|
4-(5)-(((4-ChloroMethyl)Benzoyl)AMino)TetraMethylrhodaMine is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
|
-
- HY-DY1041
-
|
|
Fluorescent Dye
|
CellTracker Blue CMAC (solution) is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels . Solution Concentration: 10 mM
|
| Cat. No. |
Product Name |
Type |
-
- HY-W013510
-
|
|
Biochemical Assay Reagents
|
|
2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W007502
-
|
Picolyl chloride hydrochloride
|
Biochemical Assay Reagents
|
|
2-(Chloromethyl)pyridine (Picolyl chloride) hydrochloride is an alkylating agent that can be used in organic synthesis reactions .
|
-
- HY-W540356
-
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P10095A
-
|
D-Val-Phe-Lys Chloromethyl ketone diTFA
|
Ser/Thr Protease
|
Metabolic Disease
|
|
D-Val-Phe-Lys-CMK (D-Val-Phe-Lys Chloromethyl ketone) diTFA can inhibit plasmin activity .
|
-
- HY-P1108A
-
|
|
CFTR
|
Others
|
|
Astressin 2B TFA is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC50 values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B TFA antagonizes CRF2-mediated inhibition of gastric emptying .
|
-
- HY-P1108
-
|
|
CFTR
|
Others
|
|
Astressin 2B is a potent and selective corticotropin-releasing factor receptor 2 (CRF2) antagonist, with the IC50 values of 1.3 nM and > 500 nM for CRF2 and CRF1, respectively. Astressin 2B antagonizes CRF2-mediated inhibition of gastric emptying .
|
-
- HY-P10579
-
123B9
1 Publications Verification
|
Ephrin Receptor
|
Cancer
|
|
123B9, a tumor-homing agent, is a potent and selective EphA2 agonist with a Kd value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. 123B9 does not appreciably inhibit the ligand binding domains of the most closely related EphA3 and EphA4 receptors .
|
-
- HY-P3066
-
|
d(CH2)5Tyr(Et)VAVP
|
Vasopressin Receptor
|
Metabolic Disease
|
|
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
|
-
- HY-P10095
-
-
- HY-P10828
-
|
|
Virus Protease
|
Infection
Inflammation/Immunology
|
|
MAPI is a polypeptide irreversible 3C cysteine protease (SV3CP) inhibitor. MAPI inhibits SV3CP by covalently binding its C-terminal Michael-acceptor extension to the active site thiol of SV3CP Cys 139. MAPI is promising for research of noroviruses infection .
|
-
- HY-P4756
-
|
|
Peptides
|
Others
|
|
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P2592
-
-
- HY-P4521
-
|
|
MMP
|
Others
|
|
Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt is a MMP12 substrate, and can be used to detect MMP12 enzyme activity .
|
-
- HY-125628
-
|
|
Endogenous Metabolite
|
Infection
|
|
Kahalalide A is an anti-mycobacterial compound with antimicrobial activity. Kahalalide A is derived from the marine mollusk Elysia rufescens. Kahalalide A has attracted extensive attention in natural product research due to its potential medicinal value .
|
-
- HY-P10272
-
|
PTG-300
|
Ferroportin
|
Others
|
|
Rusfertide is a peptide mimetic of natural hepcidin, which targets and degrades ferroportin, reduces serum iron and transferrin-saturation, and thus regulates the production of red blood cells. Rusfertide ameliorates the polycythemia vera, β-thalassemia and hereditary hemochromatosis .
|
-
- HY-A0248A
-
|
|
Bacterial
|
Infection
|
|
Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
|
-
- HY-A0248AS
-
|
|
Isotope-Labeled Compounds
Bacterial
|
Infection
|
|
Polymyxin B1-d7 TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
|
-
- HY-P10563
-
|
BHV-1100
|
CD38
|
Cancer
|
|
Noraramtide (BHV-1100) is an antibody recruitment molecule. Noraramtide can specifically bind to CD38 molecules to recruit natural killer (NK) cells. Noraramtide enhances the ability of NK cells to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while avoiding mutual killing between NK cells. Noraramtide can be used for the study of autologous cancer immunity .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W704178
-
|
|
|
N-Chloromethyl citalopram-d6 chloride is the deuterium labeled N-Chloromethyl citalopram chloride.
|
-
-
- HY-W742282
-
|
|
|
4-(Chloromethyl)-2,5-oxazolidinedione-d3 is the deuterium labeled 4-(Chloromethyl)oxazolidine-2,5-dione (HY-W703708).
|
-
-
- HY-W711764
-
|
|
|
1-Chloro-2-(chloromethyl)benzene-3,4,5,6-d4 is the deuterium labeled 1-Chloro-2-(chloromethyl)benzene (HY-W013647).
|
-
-
- HY-W654074
-
|
|
|
1,2-Dilauroyl-3-chloropropanediol-d5 (1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate-d5) is the deuterium labeled 1,2-Dilauroyl-3-chloropropanediol (HY-W587507). 1,2-Dilauroyl-3-chloropropanediol (1,1′-[1-(Chloromethyl)-1,2-ethanediyl] didodecanoate) is an ester product.
|
-
-
- HY-A0248AS
-
|
|
|
Polymyxin B1-d7 TFA is the deuterium labeled Polymyxin B1 TFA (HY-A0248A). Polymyxin B1 is a potent antimicrobial lipopeptide first derived from Bacilus polymyxa. Polymyxin B1 is the major component in Polymyxin B (HY-A0248). Polymyxin B1 can induce lysis of bacterial cells through interaction with their membranes. Polymyxin B1 has the potential for multidrug-resistant Gram-negative bacterial infections treatment .
|
-
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