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Results for "

CSD

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Peptides

1

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-123905A
    LIN28 inhibitor LI71 enantiomer

    		Drug Isomer MicroRNA Parasite Infection Cancer
    LIN28 inhibitor LI71 enantiomer is the less active enantiomer of LIN28 inhibitor LI71 (HY-123905). LIN28 inhibitor LI71 is a LIN28 inhibitor that effectively inhibits LIN28:let-7 binding (IC50: 7 μM). LIN28 inhibitor LI71 can abolish LIN28-mediated oligouridylation of let-7 precursor (IC50: 27 μM). LIN28 inhibitor LI71 has potential application value in LIN28-driven cancer research. LIN28 inhibitor LI71 inhibits the interaction of cold shock protein of Plasmodium falciparum (PfCoSP) with DNA and α/β tubulin and has an inhibitory effect on Plasmodium falciparum .
    LIN28 inhibitor LI71 enantiomer
  • HY-123905
    LIN28 inhibitor LI71

    		MicroRNA Parasite Infection Cancer
    LIN28 inhibitor LI71 is a LIN28 inhibitor that effectively inhibits LIN28:let-7 binding (IC50: 7 μM). LIN28 inhibitor LI71 can abolish LIN28-mediated oligouridylation of let-7 precursor (IC50: 27 μM). LIN28 inhibitor LI71 has potential application value in LIN28-driven cancer research. LIN28 inhibitor LI71 inhibits the interaction of cold shock protein of Plasmodium falciparum (PfCoSP) with DNA and α/β tubulin and has an inhibitory effect on Plasmodium falciparum .
    LIN28 inhibitor LI71
  • HY-110255
    AZD 2066
    1 Publications Verification

    		 mGluR Calcium Channel Trk Receptor Neurological Disease
    AZD-2066 is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 activates the BDNF/trkB signaling pathway. AZD 2066 can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease .
    AZD 2066
  • HY-P5756
    CSD-CH2(1,8)-NH2

    		Opioid Receptor Neurological Disease
    CSD-CH2(1,8)-NH2 is a selective and competitive KOR antagonist (Ki: 6.8 nM). CSD-CH2(1,8)-NH2 inhibits calcium mobilization in DRG neurons. CH2(1,8)-NH2 antagonizes the antinociceptive effect of U50,488. CSD-CH2(1,8)-NH2 can be used for research of neuropsychiatric disorders .
    CSD-CH2(1,8)-NH2
  • HY-172550
    MS7710

    		HCN Channel Neurological Disease
    MS7710 is a brain-penetrant inhibitor targeting the hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. MS7710 reduces the Ih current and decreases the activity of ventral tegmental area (VTA) dopamine neurons by inhibiting HCN channels. MS7710 can effectively improve social interaction deficits and reward-related cognitive flexibility in the chronic social defeat stress (CSDS) mouse model. MS7710 is promising for research of depression .
    MS7710
  • HY-RS19125
    Csad Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Csad Mouse Pre-designed siRNA Set A contains three designed siRNAs for Csad gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Csad Mouse Pre-designed siRNA Set A
    Csad Mouse Pre-designed siRNA Set A
  • HY-RS03222
    CSAD Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    CSAD Human Pre-designed siRNA Set A contains three designed siRNAs for CSAD gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    CSAD Human Pre-designed siRNA Set A
    CSAD Human Pre-designed siRNA Set A
  • HY-155237
    LIN28-IN-1

    		MicroRNA Cancer
    LIN28-IN-1 (compound 5) is an inhibitor of the RNA-binding and regulatory protein LIN28 and binds to the LIN28 cold shock domain (CSD). LIN28-IN-1 effectively inhibits the interaction between LIN28 and let-7 miRNA (IC50: 5.4 μM), blocking the negative impact of LIN28 on epigenetic gene regulation. LIN28-IN-1 significantly inhibits the proliferation of JAR cancer cells expressing LIN28 (IC50: 6.4 μM) .
    LIN28-IN-1
  • HY-110255A
    AZD 2066 hydrate

    		mGluR Calcium Channel Trk Receptor Neurological Disease
    AZD-2066 hydrate is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 hydrate activates the BDNF/trkB signaling pathway. AZD 2066 hydrate can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease .
    AZD 2066 hydrate
  • HY-110255B
    AZD-2066 hydrochloride

    		mGluR Calcium Channel Trk Receptor Neurological Disease
    AZD-2066 hydrochloride is a selective, orally active and blood-brain barrier-permeating mGluR5 antagonist. AZD 2066 hydrochloride activates the BDNF/trkB signaling pathway. AZD 2066 hydrochloride can be used in the research of neuropathic pain, major depressive disorder and gastroesophageal reflux disease .
    AZD-2066 hydrochloride
  • HY-RS14443
    TGFBI Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TGFBI Human Pre-designed siRNA Set A contains three designed siRNAs for TGFBI gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TGFBI Human Pre-designed siRNA Set A
    TGFBI Human Pre-designed siRNA Set A

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