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Results for "

C3 Protein (human)

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Biochemical Assay Reagents

3

Peptides

33

Recombinant Proteins

1

Isotope-Labeled Compounds

2

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P1345A
    TLQP-21 TFA
    2 Publications Verification

    		 Complement System Neurological Disease Endocrinology
    TLQP-21 TFA, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8μM). TLQP-21 TFA activates C3aR1 to induce an increase of intracellular Ca 2+. TLQP-21 TFA is used for the research in regulation of nociception and other relevant physiologic functions .
    TLQP-21 TFA
  • HY-P1363S1
    β-Amyloid (1-42), human, Ala(13C3,15N) TFA

    		Isotope-Labeled Compounds Amyloid-β Neurological Disease
    β-Amyloid (1-42), human, Ala( 13C3, 15N) TFA is the 13C and 15N-labeled β-Amyloid (1-42), human (HY-P1363A). β-Amyloid (1-42) (Amyloid β-peptide (1-42)), human, a 42-amino acid peptide that has not been treated with HFIP, is a brain-penetrant amyloid protein fragment, which can be used in research on Alzheimer's disease and Down’s syndrome. β-Amyloid (1-42), human remaining as a monomer exhibits antioxidant and neuroprotective effects. β-Amyloid (1-42), human, after being monomericized by HFIP and dissolved in DMSO to form the stock solution, on the one hand, can form soluble oligomers (AβOs) when incubated at 4 ℃, which have synaptic toxicity and neurotoxicity; on the other hand, it can be incubated at 37 ℃ to form insoluble fibrils, with lower neurotoxicity, and participating in the oxidative damage process. Aβ42 oligomers bind to various neuronal surface receptors (such as PrPc, mGluR5, NMDA receptors, etc.), triggering oxidative stress, calcium homeostasis imbalance, and synaptic toxicity via activating downstream signaling pathways, leading to neuronal dysfunction and death .
    β-Amyloid (1-42), human, Ala(13C3,15N) TFA
  • HY-NP202A
    C3 Protein (human)

    		Complement System Inflammation/Immunology
    C3 Protein (human) is a naturally glycosylated polypeptide containing two disulfide-linked chains. Complement protein C3 is a central molecule in the complement system whose activation is essential for all the important functions performed by this system .
    C3 Protein (human)
  • HY-NP202
    C2 Protein (human)

    		Complement System Inflammation/Immunology
    C2 Protein (human) is a naturally glycosylated peptide with a 20 amino acid signal sequence. Complement component C2 functions as a key regulator in the early activation phase of the classical pathway and participates in the formation of the classical pathway C3 convertase C4b2a .
    C2 Protein (human)
  • HY-P1345
    TLQP-21

    		Complement System Neurological Disease Endocrinology
    TLQP-21, a VGF-derived peptide endowed of endocrine and extraendocrine properties, is a potent G-protein-coupled receptor complement-3a receptor 1 (C3aR1) agonist (EC50: mouse TLQP-21=10.3 μM; human TLQP-21=68.8 μM). TLQP-21 activates C3aR1 to induce an increase of intracellular Ca 2+. TLQP-21 is used for the research in regulation of nociception and other relevant physiologic functions .
    TLQP-21

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