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Results for "

Arf1

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

3

Peptides

1

Recombinant Proteins

2

Antibodies

3

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112473
    Grassofermata
    5+ Cited Publications

    NAV-2729

    		 Ras Cancer
    Grassofermata is a dual Arf1/Arf6 activation inhibitor. ADP ribosylation factors (Arfs) are members of the Arf family of GTP-binding proteins of the Ras superfamily.
    Grassofermata
  • HY-P10658
    ARF1 (2-17)

    		Phospholipase Others
    ARF1 (2-17) inhibits both ARF-independent (PLC-β) and ARF-dependent (PLD) pathways. ARF1 (2-17) inhibits GTP-γ-S-stimulated PLD activity, phospholipase C-β (PLC-β), and exocytosis [1].
    ARF1 (2-17)
  • HY-RS17736
    Arf1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Arf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Arf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Arf1 Mouse Pre-designed siRNA Set A
    Arf1 Mouse Pre-designed siRNA Set A
  • HY-RS24201
    Arf1 Rat Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Arf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Arf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Arf1 Rat Pre-designed siRNA Set A
    Arf1 Rat Pre-designed siRNA Set A
  • HY-RS00894
    ARF1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    ARF1 Human Pre-designed siRNA Set A contains three designed siRNAs for ARF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ARF1 Human Pre-designed siRNA Set A
    ARF1 Human Pre-designed siRNA Set A
  • HY-175290
    Arf1-GEFs-IN-1

    		Arf Family GTPase Cancer
    Arf1-GEFs-IN-1 is a potent and orally active ADP-ribosylation factor 1- guanine nucleotide exchange factors (Arf1-GEFs) inhibitor with an IC50 value of 40.85 μM against CT26 cells. Arf1-GEFs-IN-1 primarily mediates tumor regression by triggering anti-tumor immune responses, rather than through direct cytotoxicity. Arf1-GEFs-IN-1 effectively promotes CCL5 expression, demonstrates excellent in vivo efficacy. Arf1-GEFs-IN-1 can be used for the study of colon cancer [1].
    Arf1-GEFs-IN-1
  • HY-P10157
    ARF(1-22)

    		Biochemical Assay Reagents Others
    ARF(1-22) is potentially capable of intracellular penetration to deliver small molecules, proteins, imaging agents, and pharmaceutical nanocarriers [1].
    ARF(1-22)
  • HY-P10594
    Myr-Arf1(2–17)

    		Ras Endocrinology
    Myr-Arf1(2–17) is a sarcosinated peptide that mimics the localization and function of Arf1 protein on the cell membrane. Myr-Arf1(2–17) can be used to study the desensitization mechanism of luteinizing hormone/chorionic gonadotropin receptor (LH/CGR) [1].
    Myr-Arf1(2–17)
  • HY-177269
    CHNQD-01269

    		Arf Family GTPase Cancer
    CHNQD-01269, a brefeldin A-cinnamate derivative, is an Arf1 inhibitor. CHNQD-01269 exhibits potent cytotoxic activity against HepG2 and BEL-7402 cells, with IC50 values of 0.29 and 0.84 μM, respectively. CHNQD-01269 is indicated for hepatocellular carcinoma (HCC) research [1].
    CHNQD-01269
  • HY-173280
    Brefeldin A 4-O-nicotinate

    CHNQD-01228

    		 Arf Family GTPase BMX Kinase Cancer
    Brefeldin A 4-O-nicotinate (CHNQD-01228) is a dual inhibitor of Arf1 and BMX proteins. The IC50 value for the proliferation of T24 cells is 0.22 μM. It can also dose-dependently inhibit the migration and colony formation of T24 cells, induce G1 phase arrest and trigger Apoptosis. Brefeldin A 4-O-nicotinate exerts its anti-cancer activity by targeting the BMX protein to inhibit the AKT/p-AKT and STAT3/p-STAT3 signaling pathways, as well as by inhibiting the Arf1 protein to eliminate bladder cancer stem cells and activate anti-tumor immunity. Brefeldin A 4-O-nicotinate can be used in the research related to bladder cancer [1].
    Brefeldin A 4-O-nicotinate

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