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Results for "

Anemia

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (3) Apoptosis (1) Bacterial (1) Biochemical Assay Reagents (7) Calcineurin (1) Calcium Channel (1) Caspase (1) Complement System (1) DNA Alkylator/Crosslinker (2) DNA/RNA Synthesis (5) DYRK (1) E1/E2/E3 Enzyme (1) E3 Ligase Ligand-Linker Conjugates (1) Endogenous Metabolite (24) ERK (1) Ferroportin (1) Ferroptosis (1) HBV (2) HCV (2) Herbicide (2) HIF/HIF Prolyl-Hydroxylase (28) Interleukin Related (1) Isotope-Labeled Compounds (8) MEK (1) Neuropeptide Y Receptor (1) NO Synthase (1) p38 MAPK (1) PKC (1) Potassium Channel (9) PROTACs (1) Pyruvate Kinase (3) Reactive Oxygen Species (ROS) (3) Reference Standards (9) TGF-beta/Smad (3) TGF-β Receptor (2) Transferrin Receptor (4)
By Research Areas:	Cancer (27) Cardiovascular Disease (33) Infection (3) Inflammation/Immunology (19) Metabolic Disease (28) Neurological Disease (8)
Oligonucleotides:	Nucleotides and their Analogs (2)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P3761

Ac-Tyr-Val-Lys-Asp-aldehyde	Caspase	Others
Ac-Tyr-Val-Lys-Asp-aldehyde is a caspase-1 inhibitor, can be used for disease research including anemia-associated to chronic diseases, chemotherapy-induced anemia and Diamond-Blackfan anemia .

HY-130078

Ferrous bisglycinate	Transferrin Receptor	Metabolic Disease Inflammation/Immunology
Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia .

HY-103227

Desidustat 2 Publications Verification ZYAN1	HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease
Desidustat is an orally active HIF hydroxylase inhibitor. Desidustat can be used for the research of various disorders including anemia of different types and conditions associated with ischemia/hypoxia .

HY-109690

1-(2-Amino-3-hydroxyphenyl)ethanone	Endogenous Metabolite	Cancer
1-(2-Amino-3-hydroxyphenyl)ethanone is the kynuridine metabolite, which could be extracted from rat liver mitochondrium. 1-(2-Amino-3-hydroxyphenyl)ethanone is associated with tryptophan metabolism disturbances, and can be used in bladder cancer, leukemia and anemia researches .

HY-B2209

Hydroxocobalamin 3 Publications Verification Vitamin B12a	Endogenous Metabolite	Metabolic Disease
Hydroxocobalamin (Vitamin B12a) is an injectable natural vitamin B12 with a favorable adverse effect profile for use as a dietary supplement for vitamin B12 deficiency, including pernicious anemia .

HY-15692

PHD2-IN-3	HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease
PHD2-IN-3 (compound 2) is a PHD2 inhibitor. PHD2-IN-3 can be used for study of anemia .

HY-139855

ZG-2033	HIF/HIF Prolyl-Hydroxylase	Metabolic Disease
ZG-2033 (Compound 26) is an orally active HIF-2α agonist that demonstrates nanomolar activity in luciferase reporter gene assays (EC₅₀ = 490 nM). ZG-2033 has the effect of alleviating anemia and exhibits synergistic action with AKB-6548 (HY-101277) in anemia, and can be used in the study of renal anemia .

HY-W581819

Ferric glycinate	Biochemical Assay Reagents	Others
Ferric glycinate is an iron amino acid chelate used as a food fortifier and therapeutic agent, which can prevent and ameliorate iron deficiency anemia .

HY-161660

DS44470011	HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease Metabolic Disease
DS44470011 is a hypoxia-inducing factor prolyl hydroxylase (HIF-PHD) inhibitor. DS44470011 has oral activity. DS44470011 promotes cell release of erythropoietin (EPO). DS44470011 can be used in the research of renal anemia .

HY-P991201

REGN-7257	Interleukin Related	Inflammation/Immunology
REGN-7257 is a humanized monoclonal antibody targeting IL2RG that effectively blocks signaling of all γ-c cytokines. REGN-7257 can be used in the study of aplastic anemia. The corresponding isotype control is: Human IgG4 kappa, Isotype Control (HY-P99003) .

HY-163148

PHD-IN-3	HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease
PHD-IN-3 (Compound 15) is an orally active PHD inhibitor. PHD-IN-3 can be used in the study of anemia associated with chronic kidney disease .

HY-101277

Vadadustat 5+ Cited Publications PG-1016548; AKB-6548	HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease
Vadadustat (PG-1016548) is a titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor . Vadadustat is an erythropoiesis-stimulating agent and has the potential for anemia treatment in chronic kidney disease in vivo .

HY-103227R

Desidustat (Standard) ZYAN1 (Standard)	Reference Standards HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease
Desidustat (Standard) is the analytical standard of Desidustat. This product is intended for research and analytical applications. Desidustat is an orally active HIF hydroxylase inhibitor. Desidustat can be used for the research of various disorders including anemia of different types and conditions associated with ischemia/hypoxia .

HY-108017

Ferric maltol	Others	Metabolic Disease Cancer
Ferric maltol is an orally active monovalent iron (Fe ³⁺) complex. Ferric maltol is used in the study of iron deficiency anemia in inflammatory bowel disease .

HY-172803

Ferroptosis inducer-7	Ferroptosis ERK MEK p38 MAPK	Inflammation/Immunology
Ferroptosis inducer-7 is an orally active and selective ferroptosis inducer via inositol 1,4,5-trisphosphate receptor (IP₃R)/calcium release-activated calcium channel protein (ORAI). Ferroptosis inducer-7 exhibits a notable effect in alleviating anemia symptoms, suppressing bone marrow CTLs activation, and improving hematopoietic function in immune-mediated bone marrow failure. Ferroptosis inducer-7 can be studied in research for aplastic anemia .

HY-147379

Hepcidin antagonist-1	Ferroportin	Metabolic Disease
Hepcidin antagonist-1 (example 104) is a potent hepcidin (hepcidine) antagonist with an IC₅₀<50 μM. Hepcidin antagonist-1 can be used for researching iron metabolism disorders, such as anemias .

HY-B2209R

Hydroxocobalamin (Standard) Vitamin B12a (Standard)	Reference Standards Endogenous Metabolite	Metabolic Disease
Hydroxocobalamin (Standard) is the analytical standard of Hydroxocobalamin. This product is intended for research and analytical applications. Hydroxocobalamin (Vitamin B12a) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-131346

HIF-PHD-IN-1	HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease
HIF-PHD-IN-1 is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase domain (HIF-PHD), with an IC₅₀ of 54 nM for hHIF-PHD2. HIF-PHD-IN-1 is promising therapeutic agents for renal anemia .

HY-106950S1

Fosfructose-13C6 tetrasodium hydrate Diphosphofructose-¹³C₆ tetrasodium hydrate; Esafosfan-¹³C₆ tetrasodium hydrate; FDP-¹³C₆ tetrasodium hydrate	Endogenous Metabolite	Cardiovascular Disease
Fosfructose- ¹³C₆ (tetrasodium hydrate) is the ¹³C labeled Fosfructose (HY-106950). Fosfructose is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma .

HY-155009

PHD2-IN-1	HIF/HIF Prolyl-Hydroxylase	Others
PHD2-IN-1 is a potent and orally active inhibitor of HIF prolyl hydroxylase 2 (PHD2) with an IC₅₀ of 22.53 nM. PHD2-IN-1 can be used for anemia research .

HY-162438

PHD2-IN-2	HIF/HIF Prolyl-Hydroxylase	Metabolic Disease
PHD2-IN-2 (Compound 12) is a PHD2 inhibitor, with an IC₅₀ of 34.3 nM. PHD2-IN-2 has high erythropoietin (EPO) inducing activity, with an EC₅₀ of 6.79 μM. PHD2-IN-2 can be used for the research of anemia, ischemia, and hypoxia .

HY-108017R

Ferric maltol (Standard)	Others	Metabolic Disease Cancer
Ferric maltol (Standard) is the analytical standard of Ferric maltol. This product is intended for research and analytical applications. Ferric maltol is an orally active monovalent iron (Fe3+) complex. Ferric maltol is used in the study of iron deficiency anemia in inflammatory bowel disease .

HY-B2068

Iron sucrose 1 Publications Verification Iron saccharate	Reactive Oxygen Species (ROS)	Metabolic Disease Cancer
Iron sucrose (Iron saccharate) is a intravenous iron preparation and a pro-oxidant agent. Iron sucrose has the potential for iron deficiency anemia treatment .

HY-145608

Zilurgisertib INCB-000928; NBU-928	TGF-β Receptor	Cardiovascular Disease Cancer
Zilurgisertib (INCB-000928; NBU-928) is a selective ALK2 inhibitor with an IC₅₀ value of 15 nM. Zilurgisertib inhibits SMAD1/5 phosphorylation with an IC₅₀ value of 63 nM. Zilurgisertib inhibits hepcidin production and improve anemia. Zilurgisertib can be used in melanoma research .

HY-125862

Glutathione Reductase, baker's yeast EC 1.6.4.2; GR	Calcineurin Reactive Oxygen Species (ROS)	Cardiovascular Disease Neurological Disease
Glutathione reductase, baker's yeast (EC 1.6.4.2) is a reductase. Glutathione reductase, baker's yeast eliminates intracellular ROS. Glutathione reductase, baker's yeast reduces oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as an electron donor. Glutathione reductase, baker's yeast exerts antioxidant activity. Glutathione reductase is mainly used to study diseases associated with oxidative stress, such as Parkinson's disease and sickle cell anemia .

HY-P99720

Luspatercept 2 Publications Verification ACE-536; luspatercept–aamt	TGF-beta/Smad	Metabolic Disease Cancer
Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia .

HY-Y1620

3-(3,4-Dimethoxyphenyl)propanoic acid	Biochemical Assay Reagents	Cardiovascular Disease
3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias .

HY-136055

(S,R,S)-AHPC-C5-COOH VH032-C5-COOH	E3 Ligase Ligand-Linker Conjugates HIF/HIF Prolyl-Hydroxylase	Cancer
(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate, contains the VH032 VHL-based ligand and a linker to form PROTACs. VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a K_d of 185 nM, has the potential for the study of anemia and ischemic diseases .

HY-147025

(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine 1 Publications Verification	PROTACs TGF-beta/Smad HIF/HIF Prolyl-Hydroxylase	Inflammation/Immunology
(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual target PROTAC that can not only target to the ubiquitination and degradation of Smad3 but also improve the HIF-α protein level. (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine has a multi-path anti-fibrosis function and a renal protection function for research of renal anemia .

HY-P990025

Empasiprubart ARGX-117	Complement System	Inflammation/Immunology
Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models .

HY-113066

Guanosine 5'-diphosphate GDP	Endogenous Metabolite Potassium Channel	Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-W747868

Molidustat sodium	HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease
Molidustat sodium is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with IC₅₀ values of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD3, respectively. Molidustat sodium can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat sodium can be utilized in the research of renal anemia .

HY-113066B

Guanosine 5'-diphosphate ditromethamine GDP ditromethamine	Potassium Channel Endogenous Metabolite	Inflammation/Immunology
Guanosine 5'-diphosphate ditromethamine is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate ditromethamine is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate ditromethamine can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-12654

Molidustat 5+ Cited Publications BAY 85-3934	HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease
Molidustat (BAY 85-3934) is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with IC₅₀ values of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD3, respectively. Molidustat can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat can be utilized in the research of renal anemia .

HY-Y1103

Iron(II) sulfate heptahydrate, 99% Ferrous sulfate heptahydrate, 99%	Biochemical Assay Reagents	Cardiovascular Disease Cancer
Iron(II) sulfate heptahydrate, 99% (Ferrous sulfate heptahydrate, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer .

HY-113066C

Guanosine 5'-diphosphate (sodium), 96% (HPLC) 2 Publications Verification GDP (sodium), Type I, 96% (HPLC)	Endogenous Metabolite Potassium Channel	Inflammation/Immunology Cancer
Guanosine 5'-diphosphate (sodium), 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, Type I, 96% (HPLC) is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate (sodium), 96% (HPLC) can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-16637D

Folic acid disodium Maximum Cited Publications 17 Publications Verification Vitamin B9 disodium; Vitamin M disodium	Endogenous Metabolite DNA/RNA Synthesis	Others Neurological Disease Cancer
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 ⁵ g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .

HY-Y1103A

Iron(II) sulfate heptahydrate, for cell culture, 99% Ferrous sulfate heptahydrate, for cell culture, 99%	Biochemical Assay Reagents	Cardiovascular Disease Cancer
Iron(II) sulfate heptahydrate, for cell culture, 99% (Ferrous sulfate heptahydrate, for cell culture, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, for cell culture, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, for cell culture, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, for cell culture, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer .

HY-P99720A

Luspatercept (mIgG2a) RAP-536	TGF-beta/Smad	Metabolic Disease
Luspatercept (mIgG2a) (RAP-536) is a fusion protein, consisting of a modified extracellular domain of human ActRIIB linked to the murine IgG2a Fc domain. Luspatercept (mIgG2a) inhibits Smad2/3 signaling, promotes differentiation of late-stage erythroid precursors and mitigates ineffective erythropoiesis (IE) in murine β-thalassemia. Luspatercept (mIgG2a) reduces anemia, α-globin aggregates, hemolysis, and disease complications of IE such as iron overload, splenomegaly, and bone defects .

HY-113066S2

Guanosine 5'-diphosphate-d13 dilithium GDP-d¹³ dilithium	Isotope-Labeled Compounds Endogenous Metabolite Potassium Channel	Inflammation/Immunology
Guanosine 5'-diphosphate-d₁₃ (GDP-d₁₃) dilithium is deuterium labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-12654R

Molidustat (Standard)	HIF/HIF Prolyl-Hydroxylase	Cardiovascular Disease
Molidustat (Standard) is the analytical standard of Molidustat. This product is intended for research and analytical applications. Molidustat (BAY 85-3934) is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH) with IC50 values of 480 nM, 280 nM, and 450 nM for PHD1, PHD2, and PHD3, respectively. Molidustat can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat can be utilized in the research of renal anemia .

HY-113066S1

Guanosine 5'-diphosphate-13C10 dilithium GDP-¹³C₁₀ dilithium	Isotope-Labeled Compounds Endogenous Metabolite Potassium Channel	Inflammation/Immunology
Guanosine 5'-diphosphate- ¹³C₁₀ (GDP- ¹³C₁₀) dilithium is ¹³C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-113066S

Guanosine 5'-diphosphate-15N5 dilithium GDP-¹⁵N₅ dilithium	Isotope-Labeled Compounds Endogenous Metabolite Potassium Channel	Inflammation/Immunology
Guanosine 5'-diphosphate- ¹⁵N₅ (GDP- ¹⁵N₅) dilithium is ¹⁵N labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-113066S3

Guanosine 5'-diphosphate-13C10,15N5 dilithium GDP-¹³C₁₀,¹⁵N₅ dilithium	Isotope-Labeled Compounds Endogenous Metabolite Potassium Channel	Inflammation/Immunology
Guanosine 5'-diphosphate- ¹³C₁₀, ¹⁵N₅ (GDP- ¹³C₁₀, ¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-107928

Iron dextran Fe dextran	Transferrin Receptor	Metabolic Disease Cancer
Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals .

HY-44809A

Izilendustat hydrochloride	HIF/HIF Prolyl-Hydroxylase	Inflammation/Immunology Cancer
Izilendustat (hydrochloride) is a potent inhibitor of prolyl hydroxylase which stabilizes hypoxia inducible factor- 1 alpha (HIF- lα), as well as hypoxia inducible factor-2 (HIF-2). Izilendustat (hydrochloride) has the potential for the research of HIF- lα related diseases including Peripheral Vascular Disease (PVD), Coronary Artery Disease (CAD), heart failure, ischemia, anemia, colitis, and other inflammatory bowel diseases (extracted from patent WO2011057115A1/WO2011057112A1/WO2011057121A1) .

HY-N13061

Nervon	Others	Neurological Disease
Nervon is a crystalline cerebroside. Nervon can be used for the research of peripheral neuropathies and megaloblastic anemia caused by vitamin B12 deficiency .

HY-170915

DDO-3055	HIF/HIF Prolyl-Hydroxylase	Others
DDO-3055 is an orally active PHD2 inhibitor that can be used in the research of anemia associated with chronic kidney disease .

HY-I0466

Glutarimide	Calcium Channel	Cardiovascular Disease
Glutarimide is an important part of many compounds displaying biological activity. Glutarimide is promising for research of anemia, multiple myeloma and cycloheximide .

HY-112144

TP0463518 1 Publications Verification	HIF/HIF Prolyl-Hydroxylase	Metabolic Disease Inflammation/Immunology
TP0463518 is an orally active, competitive pan-inhibitor of hypoxia-inducible factor prolyl hydroxylases PHD1/2/3. TP0463518 competitively inhibits human PHD1 (IC₅₀=18 nM), PHD2 (K_i=5.3 nM), and PHD3 (IC₅₀=63 nM), and targets monkey PHD2 with an IC₅₀ of 22 nM. TP0463518 inhibits PHD-catalyzed hydroxylation to stabilize HIFα, thereby upregulating erythropoietin (EPO) expression and enhancing intestinal iron absorption (such as increased DMT-1 and dCYTb expression), improving anemia. TP0463518 is mainly used for the research of renal anemia and inflammatory anemia .

Cat. No.	Product Name

HY-L171

Anti-Hematopathy Compound Library

3,497 compounds

Hematopathy, also known as hematopoietic system diseases, are a class of diseases that hematopoietic system has abnormal changes. Common hematopathy include: aplastic anemia, myeloproliferative diseases, thalassemia, leukemia, lymphoma, myeloma and hemophilia, etc. In recent years, treatments for hematopathy have been developed. In particular, the treatment of malignant hematopathy developed from chemotherapy, radiotherapy, bone marrow development to immunotherapy, induced differentiation therapy, cell therapy, gene therapy and hematopoietic stem cell transplantation. Although these therapies have greatly improved the survival rate of patients, there are still problems such as low cure rate and easy recurrence in the treatment of hematopathy. Therefore, it is of great significance to actively search for new hematopathy therapeutic drugs.

MCE designs a unique collection of 3,497 anti-hematopathy small molecules, which is an effective tool for development and research of anti-hematopathy compounds.

Cat. No.	Product Name	Type

HY-Y1103

Iron(II) sulfate heptahydrate, 99%

Ferrous sulfate heptahydrate, 99%

Buffer Reagents

Iron(II) sulfate heptahydrate, 99% (Ferrous sulfate heptahydrate, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer .

HY-113066C

Guanosine 5'-diphosphate (sodium), 96% (HPLC)

2 Publications Verification

GDP (sodium), Type I, 96% (HPLC)

Gene Sequencing and Synthesis

Guanosine 5'-diphosphate (sodium), 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, Type I, 96% (HPLC) is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate (sodium), 96% (HPLC) can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-Y1103A

Iron(II) sulfate heptahydrate, for cell culture, 99%

Ferrous sulfate heptahydrate, for cell culture, 99%

Buffer Reagents

Iron(II) sulfate heptahydrate, for cell culture, 99% (Ferrous sulfate heptahydrate, for cell culture, 99%) is an orally active iron salt. Iron(II) sulfate heptahydrate, for cell culture, 99% replaces iron found in hemoglobin and myoglobin, allowing for the transportation of oxygen via hemoglobin. Iron(II) sulfate heptahydrate, for cell culture, 99% is mainly used for the prevention of iron-deficiency anemia. Iron(II) sulfate heptahydrate, for cell culture, 99% also has anti-tumor effects on chronic myeloid leukemia and breast cancer .

HY-47030

Ferric citrate hydrate	Microbial Culture
Ferric citrate hydrate, an orally active iron supplement, is an efficacious phosphate binder. Ferric citrate hydrate can be used for iron deficiency anemia and chronic kidney disease (CKD) research .

HY-W127737

Methylcobalamin hydrate

Mecobalamin hydrate

Biochemical Assay Reagents

Methylcobalamin Hydrate is a coenzyme required for methionine biosynthesis. Vitamins (hematopoiesis). It acts as a histamine receptor, Alzheimer study. Methylcobalamin is also used in the research of peripheral neuropathy, diabetic neuropathy, and as an initial research for amyotrophic lateral sclerosis. It can be used to prevent or research pathologies caused by vitamin B12 deficiency, such as pernicious anemia.

HY-107928A

Iron–Dextran(Fe 25-35% w/w)

Cell Assay Reagents

Iron-Dextran is an injectable complex of iron and dextran, a complex carbohydrate. It is often used to improve iron deficiency anemia, a condition characterized by low levels of iron in the blood due to insufficient dietary intake or malabsorption. Iron-glucan works by providing a source of supplemental iron that the body can use to produce hemoglobin, the protein responsible for carrying oxygen in the blood. However, caution should be exercised when taking iron dextran because it may cause hypersensitivity reactions, including anaphylaxis, and may also increase the risk of infection or other adverse reactions. Therefore, it should only be administered under the supervision of a qualified healthcare provider in a clinical setting.

Cat. No.	Product Name	Target	Research Area

HY-P3761

Ac-Tyr-Val-Lys-Asp-aldehyde	Caspase	Others
Ac-Tyr-Val-Lys-Asp-aldehyde is a caspase-1 inhibitor, can be used for disease research including anemia-associated to chronic diseases, chemotherapy-induced anemia and Diamond-Blackfan anemia .

HY-P5908

DEALA-Hyp-YIPD	Peptides	Cardiovascular Disease
DEALA-Hyp-YIPD is an HIF-1α peptide that inhibits VHL/HIF-1α interaction with an IC₅₀ of 0.91 μM and a K_d of 180 nM .

Cat. No.	Product Name	Target	Research Area

HY-P99720

Luspatercept 2 Publications Verification ACE-536; luspatercept–aamt	TGF-beta/Smad	Metabolic Disease Cancer
Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia .

HY-P990025

Empasiprubart ARGX-117	Complement System	Inflammation/Immunology
Empasiprubar (ARGX-117) is a humanized inhibitory monoclonal antibody targeting complement C2. Empasiprubar binds to the Sushi-2 domain of C2, preventing the formation of C3 pre convertase and inhibiting the activation of classical and lectin pathways upstream of C3 activation. Empasiprubar can prevent complement mediated autoimmune hemolytic anemia and antibody mediated organ transplant rejection. Empasiprubar can prevent neuroglial lymphoconjunctival injury in GM1 antibody mediated mouse models .

HY-P99590

Sotatercept ACE-011	TGF-β Receptor	Cardiovascular Disease Inflammation/Immunology Cancer
Sotatercept (ACE-011) is a soluble activin receptor 2A (ACVR2A) type IgG Fc fusion protein. Sotatercept combines activin and growth differentiation factor to try to restore the balance between growth promotion and growth inhibition signal pathways. Sotatercept has potential application in pulmonary arterial hypertension, anemia, bone loss, erythropoiesis, multiple myeloma (MM) osteolytic lesions .

HY-P991201

REGN-7257	Interleukin Related	Inflammation/Immunology
REGN-7257 is a humanized monoclonal antibody targeting IL2RG that effectively blocks signaling of all γ-c cytokines. REGN-7257 can be used in the study of aplastic anemia. The corresponding isotype control is: Human IgG4 kappa, Isotype Control (HY-P99003) .

HY-P99720A

Luspatercept (mIgG2a) RAP-536	TGF-beta/Smad	Metabolic Disease
Luspatercept (mIgG2a) (RAP-536) is a fusion protein, consisting of a modified extracellular domain of human ActRIIB linked to the murine IgG2a Fc domain. Luspatercept (mIgG2a) inhibits Smad2/3 signaling, promotes differentiation of late-stage erythroid precursors and mitigates ineffective erythropoiesis (IE) in murine β-thalassemia. Luspatercept (mIgG2a) reduces anemia, α-globin aggregates, hemolysis, and disease complications of IE such as iron overload, splenomegaly, and bone defects .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B2209

Hydroxocobalamin 3 Publications Verification Vitamin B12a	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxocobalamin (Vitamin B12a) is an injectable natural vitamin B12 with a favorable adverse effect profile for use as a dietary supplement for vitamin B12 deficiency, including pernicious anemia .

HY-113066C

Guanosine 5'-diphosphate (sodium), 96% (HPLC) 2 Publications Verification GDP (sodium), Type I, 96% (HPLC)	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Potassium Channel
Guanosine 5'-diphosphate (sodium), 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, Type I, 96% (HPLC) is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate (sodium), 96% (HPLC) can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-16637D

Folic acid disodium Maximum Cited Publications 17 Publications Verification Vitamin B9 disodium; Vitamin M disodium	Structural Classification Natural Products Neurological Disease Classification of Application Fields Source classification Endogenous metabolite Disease Research Fields Cancer	Endogenous Metabolite DNA/RNA Synthesis
Folic acid disodium (Vitamin B9 disodium; Vitamin M disodium) is an orally active disodium salt form of Folic acid (HY-16637) with an intrinsic dissolution rate (IDR) of 4.96·10 ⁵ g/s . Folic acid disodium serves as cofactor in single-carbon transfer reactions and exhibits protective effects against neural tube defects, ischemic events, and cancer. Folate acid disodium overload leads to impaired brain development in embryogenesis and promotes growth of precancerous altered cells. Folic acid deficiency leads to megaloblastic anemia .

HY-113066A

Guanosine 5'-diphosphate disodium salt 2 Publications Verification GDP disodium salt	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite Potassium Channel
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-106950

Fosfructose Diphosphofructose; Esafosfan; FDP	Cardiovascular Disease Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Fosfructose (Diphosphofructose;Esafosfan;FDP) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. It acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions.

HY-106950A

Fosfructose trisodium Diphosphofructose trisodium; Esafosfan trisodium; FDP trisodium	Cardiovascular Disease Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Fosfructose trisodium (Diphosphofructose trisodium;Esafosfan trisodium;FDP trisodium) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. It acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions.

HY-B2209R

Hydroxocobalamin (Standard) Vitamin B12a (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Hydroxocobalamin (Standard) is the analytical standard of Hydroxocobalamin. This product is intended for research and analytical applications. Hydroxocobalamin (Vitamin B12a) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-113066

Guanosine 5'-diphosphate GDP	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Nervous System Disorder Endogenous metabolite Inflammation/Immunology Disease Research Fields Cardiovascular System Disorder	Endogenous Metabolite Potassium Channel
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-N13061

Nervon	Structural Classification Animals Source classification Saccharides Monosaccharides	Others
Nervon is a crystalline cerebroside. Nervon can be used for the research of peripheral neuropathies and megaloblastic anemia caused by vitamin B12 deficiency .

HY-113066AR

Guanosine 5'-diphosphate disodium salt (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Endogenous Metabolite Potassium Channel
Guanosine 5'-diphosphate (disodium salt) (Standard) is the analytical standard of Guanosine 5'-diphosphate (disodium salt). This product is intended for research and analytical applications. Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-B2209A

Hydroxocobalamin monohydrochloride 3 Publications Verification Vitamin B12a monohydrochloride	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-B2209B

Hydroxocobalamin acetate 3 Publications Verification Vitamin B12a acetate	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	NO Synthase
Hydroxocobalamin acetate is an injectable natural vitamin B12. Hydroxocobalamin acetate binds to NO. Hydroxocobalamin acetate detoxifies Cyanide and NaSH. Hydroxocobalamin acetate reduces hypotension. Hydroxocobalamin acetate is used in research related to vitamin B12 deficiency, including pernicious anemia .

HY-B2209BR

Hydroxocobalamin acetate (Standard) Vitamin B12a acetate (Standard)	Structural Classification Natural Products Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Hydroxocobalamin (acetate) (Standard) is the analytical standard of Hydroxocobalamin (acetate). This product is intended for research and analytical applications. Hydroxocobalamin acetate is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the research of vitamin B12 deficiency including pernicious anemia .

HY-16637A

Folic acid sodium Vitamin B9 sodium; Vitamin M sodium	Neurological Disease Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Endogenous Metabolite
Folic acid (Vitamin B9) sodium is a orally active essential nutrient from the B complex group of vitamins. Folic acid sodium shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid sodium can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-16637

Folic acid Maximum Cited Publications 17 Publications Verification Vitamin B9; Vitamin M	Structural Classification Neurological Disease Classification of Application Fields Anti-aging Source classification Endocrine diseases Plants Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms other families Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Disease Research Fields Cancer	DNA/RNA Synthesis Endogenous Metabolite
Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-B2209AR

Hydroxocobalamin monohydrochloride (Standard) Vitamin B12a monohydrochloride (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Source classification Endogenous metabolite	Reference Standards Endogenous Metabolite
Hydroxocobalamin (monohydrochloride) (Standard) is the analytical standard of Hydroxocobalamin (monohydrochloride). This product is intended for research and analytical applications. Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-N2754

Sternbin Eriodictyol 7-methyl ether; 7-O-Methyleriodictyol	Structural Classification Flavonoids Flavonones Source classification Plants Compositae Crotalaria candicans Wight & Arn.	Bacterial
Sternbin (Eriodictyol 7-methyl ether) is a flavanone and antibacterial agent. Sternbin can be isolated from Heliotropium sinuatum. Sternbin has antibacterial activity against a wide range of bacteria. Sternbin has antiviral activity against infectious salmon anemia virus (ISAV). Sternbin inhibits the contraction of isolated rat smooth muscle .

HY-16637R

Folic acid (Standard) Vitamin B9 (Standard); Vitamin M (Standard)	Structural Classification Human Gut Microbiota Metabolites Microorganisms other families Ketones, Aldehydes, Acids Source classification Disease markers Endocrine diseases Nervous System Disorder Plants Endogenous metabolite	Reference Standards DNA/RNA Synthesis Endogenous Metabolite
Folic acid (Standard) is the analytical standard of Folic acid. This product is intended for research and analytical applications. Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

HY-137295

Ingenol 3,20-dibenzoate	Classification of Application Fields Terpenoids Source classification Diterpenoids Euphorbia esula L. Euphorbiaceae Plants Inflammation/Immunology Disease Research Fields	PKC Apoptosis
Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells .

HY-113427AR

cis-Vaccenic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Antibiotic Reference Standards
cis-Vaccenic acid (Standard) is the analytical standard of cis-Vaccenic acid. This product is intended for research and analytical applications. cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate , acts a potential fetal hemoglobin inducer .

HY-113427A

cis-Vaccenic acid	Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields Cancer	Antibiotic
cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate , acts a potential fetal hemoglobin inducer .

Species:	Human (2)
Tag:	His (2) SUMO (1)
Source:	Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P72190

	FANCC Protein, Human (His-SUMO) bA80I15.1; FA3; FAC; FACC; FANCC; FANCC_HUMAN; Fanconi Anemia complementation group C; Fanconi Anemia complementation group C protein; Fanconi Anemia group C protein; Fanconi pancytopenia type 3; FLJ14675; Protein FACC	Human	E. coli
	FANCC Protein repairs and maintains DNA, aids in STAT1 activation, and forms a multisubunit FA complex. It interacts with ZBTB32, STAT1, CDK1, and EIF2AK2. The FA complex excludes FA patients and may include HSP70, while interaction with EIF2AK2 leads to increased activation and cell death. FANCC Protein, Human (His-SUMO) is the recombinant human-derived FANCC protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P76915

	FACA/FANCA Protein, Human (sf9, His) Fanconi Anemia group A protein; FAA; FACA; FANCH	Human	Sf9 insect cells
	FANCA/FANCC proteins repair DNA and maintain chromosomal stability. FACA/FANCA Protein, Human (sf9, His) is the recombinant human-derived FACA/FANCA protein, expressed by Sf9 insect cells , with N-His labeled tag.

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HY-106950S1

Fosfructose-13C6 tetrasodium hydrate
Fosfructose- ¹³C₆ (tetrasodium hydrate) is the ¹³C labeled Fosfructose (HY-106950). Fosfructose is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma .

HY-113066S

Guanosine 5'-diphosphate-15N5 dilithium

Guanosine 5'-diphosphate- ¹⁵N₅ (GDP- ¹⁵N₅) dilithium is ¹⁵N labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-113066S2

Guanosine 5'-diphosphate-d13 dilithium

Guanosine 5'-diphosphate-d₁₃ (GDP-d₁₃) dilithium is deuterium labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-113066S1

Guanosine 5'-diphosphate-13C10 dilithium

Guanosine 5'-diphosphate- ¹³C₁₀ (GDP- ¹³C₁₀) dilithium is ¹³C-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-113066S3

Guanosine 5'-diphosphate-13C10,15N5 dilithium

Guanosine 5'-diphosphate- ¹³C₁₀, ¹⁵N₅ (GDP- ¹³C₁₀, ¹⁵N₅) dilithium is ¹³C and ¹⁵N-labeled Guanosine 5'-diphosphate (HY-113066). Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI).

HY-N6692S

Diacetoxyscirpenol-13C19
Diacetoxyscirpenol- ¹³C₁₉ is ¹³C labeled Diacetoxyscirpenol (HY-N6692). Diacetoxyscirpenol (DAS) is a trichothecene mycotoxin, a secondary metabolite product of fungi. Diacetoxyscirpenol (DAS) consumption induces haematological disorders (neutropenia, aplastic anemia) in human and animals .

HY-101277S1

Vadadustat-13C6
Vadadustat- ¹³C₆ (PG-1016548- ¹³C₆) is ¹³C labeled Vadadustat. Vadadustat (PG-1016548) is a titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor . Vadadustat is an erythropoiesis-stimulating agent and has the potential for anemia treatment in chronic kidney disease in vivo .

HY-Y1620S

3-(3,4-Dimethoxyphenyl)propanoic acid-d10
3-(3,4-Dimethoxyphenyl)propanoic acid-d₁₀ is the deuterium labeled 3-(3,4-Dimethoxyphenyl)propanoic acid. 3-(3,4-Dimethoxyphenyl)propanoic acid is an orally active short-chain fatty acids (SCFAs). 3-(3,4-Dimethoxyphenyl)propanoic acid stimulates γ globin gene expression, erythropoiesis in vivo and is used for the β hemoglobinopathies and other anemias .

HY-16637S5

Folic acid-13C6
Folic acid-13C6 is a deuterated labeled Folic acid . Folic acid (Vitamin B9) is a orally active essential nutrient from the B complex group of vitamins. Folic acid shows antidepressant-like effect. Folic acid sodium reduces the risk of neonatal neural tube defects. Folic acid can be used to the research of megaloblastic and macrocytic anemias due to folic deficiency .

Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83121

	Cubilin Antibody (YA2866) Cubilin; Cubn; IFCR; MGA1; Cubilin precursor; megaloblastic Anemia 1	WB, IHC-P	Human
	Cubilin Antibody (YA2866) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2866), targeting Cubilin, with a predicted molecular weight of 399 kDa (observed band size: 399 kDa). Cubilin Antibody (YA2866) can be used for WB, IHC-P experiment in human background.

HY-P83357

	FANCD2 Antibody (YA3102) FA D2; FA4; FAC D2; FACD 2; FACD; FACD2; FAD; FAD2; FANCD 2; FANCD; FANCD2; Fanconi Anemia group D2 protein; FLJ23826; Protein FACD2; Type 4 Fanconi pancytopenia	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	FANCD2 Antibody (YA3102) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3102), targeting FANCD2, with a predicted molecular weight of 164 kDa (observed band size: 164 kDa). FANCD2 Antibody (YA3102) can be used for WB, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

HY-P83059

	FANCB Antibody (YA2804) Fanconi Anemia complementation group B; FA2; FAB; FACB; FAAP90; FAAP95	WB	Human, Mouse
	FANCB Antibody (YA2804) is a non-conjugated IgG antibody, targeting FANCB, with a predicted molecular weight of 98 kDa (observed band size: 98 kDa). FANCB Antibody (YA2804) can be used for WB experiment in human, mouse background.

HY-P86790

	BRCA2 Antibody (YA6483) BRCA 2 antibody; BRCA1/BRCA2 containing complex subunit 2 antibody; Brca2 antibody; BRCA2, DNA repair associated antibody; BRCA2_HUMAN antibody; BRCC 2 antibody; BRCC2 antibody; Breast and ovarian cancer susceptibility gene early onset antibody; breast and ovarian cancer susceptibility protein 2 antibody; Breast cancer 2 early onset antibody; BRCA 2 antibody; BRCA1/BRCA2 containing complex subunit 2 antibody; Brca2 antibody; BRCA2, DNA repair associated antibody; BRCA2_HUMAN antibody; BRCC 2 antibody; BRCC2 antibody; Breast and ovarian cancer susceptibility gene early onset antibody; breast and ovarian cancer susceptibility protein 2 antibody; Breast cancer 2 early onset antibody; Breast Cancer 2 tumor suppressor antibody; Breast cancer susceptibility protein BRCA2 antibody; Breast cancer type 2 susceptibility protein antibody; BROVCA2 antibody; FACD antibody; FAD 1 antibody; FAD antibody; FAD1 antibody; FANCB antibody; FANCD 1 antibody; FANCD antibody; FANCD1 antibody; FANCD1 gene antibody; Fanconi Anemia complementation group D1 antibody; Fanconi Anemia group D1 protein antibody; GLM3 antibody; mutant BRCA2 antibody; OTTHUMP00000018803 antibody; OTTHUMP00000042401 antibody; PNCA2 antibody; XRCC11 antibody	WB, FC	Human

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Cat. No.	Product Name		Classification

HY-113066A

Guanosine 5'-diphosphate disodium salt 2 Publications Verification GDP disodium salt		Nucleotides and their Analogs
Guanosine 5'-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5'-diphosphate disodium salt activates adenosine 5'-triphosphate-sensitive K ⁺ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5'-diphosphate disodium salt is a potential iron mobilizer, which prevents the Hepcidin (HY-P70400)-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Elevated levels of guanosine 5’-diphosphate are associated with the pathogenesis of neurological diseases. Guanosine 5'-diphosphate disodium salt is promising for the research of inflammation, such as anemia of inflammation (AI) .

HY-113066

Guanosine 5'-diphosphate GDP		Nucleotides and their Analogs
Guanosine 5'-diphosphate (GDP) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate can be used in the research of inflammation, such as anemia of inflammation (AI) .

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