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Results for "

2'-Deoxy-2'-fluorouridine

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Isotope-Labeled Compounds

6

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W013403
    2'-Deoxy-2'-fluorouridine

    		IFNAR Infection
    2'-Deoxy-2'-fluorouridine is a derivative of the pyrimidine nucleoside uridine. 2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. Hepatitis C polyU/UC RNA strands containing 2'-Deoxy-2'-fluorouridine, bind to RIG-I but do not activate RIG-I signaling in a reporter assay using Huh7 cells. 2'-Deoxy-2'-fluorouridine also has been used as a starting material in the synthesis of respiratory syncytial virus (RSV) polymerase inhibitors. 2'-Deoxy-2'-fluorouridine can incorporate into DNA and RNA in rat and woodchuck model upon administration. 2'-Deoxy-2'-fluorouridine can be studied in anti-viral research .
    2'-Deoxy-2'-fluorouridine
  • HY-45492
    DMT-2'Fluoro-DG(IB) Amidite

    2'-F-ibu-dG Phosphoramidite

    		 Nucleoside Antimetabolite/Analog Others
    DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine .
    DMT-2'Fluoro-DG(IB) Amidite
  • HY-W013403S
    2'-Deoxy-2'-fluorouridine-d2

    		IFNAR Infection
    2'-Deoxy-2'-fluorouridine-d2 is the deuterium labeled 2'-Deoxy-2'-fluorouridine . 2'-Deoxy-2'-fluorouridine is a derivative of the pyrimidine nucleoside uridine. 2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. Hepatitis C polyU/UC RNA strands containing 2'-Deoxy-2'-fluorouridine, bind to RIG-I but do not activate RIG-I signaling in a reporter assay using Huh7 cells. 2'-Deoxy-2'-fluorouridine also has been used as a starting material in the synthesis of respiratory syncytial virus (RSV) polymerase inhibitors. 2'-Deoxy-2'-fluorouridine can incorporate into DNA and RNA in rat and woodchuck model upon administration. 2'-Deoxy-2'-fluorouridine can be studied in anti-viral research .
    2'-Deoxy-2'-fluorouridine-d2
  • HY-148957
    5-Bromo-2′-deoxy-2′-fluorouridine

    		Virus Protease Infection
    5-Bromo-2′-deoxy-2′-fluorouridine (Example 1), a 5-halo analog, is potential as an antiviral agent .
    5-Bromo-2′-deoxy-2′-fluorouridine
  • HY-154059
    2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium

    		Nucleoside Antimetabolite/Analog Cancer
    2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium
  • HY-154813
    3′,5′-Di-O-acetyl-2′-deoxy-2′-fluorouridine

    		Nucleoside Antimetabolite/Analog Others
    3′,5′-Di-O-acetyl-2′-deoxy-2′-fluorouridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents .
    3′,5′-Di-O-acetyl-2′-deoxy-2′-fluorouridine
  • HY-41793
    3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine

    2'-Deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluorouridine

    		 Nucleoside Antimetabolite/Analog Cancer
    3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
    3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine
  • HY-164252
    DMT-2'-F-U

    5′-O-Trityl-2′-Deoxy-2′-fluorouridine

    		 DNA/RNA Synthesis Others
    DMT-2'-FU (5'-O-Trityl-2'-deoxy-2'-fluorouridine)Is with DMTProtecting Group (Protect 5'end), FLabeled uridine ribonucleotide.
    DMT-2'-F-U
  • HY-154080
    5'-O-DMTr-2'-FU-methyl phosphonamidite

    		DNA/RNA Synthesis Others
    5’-O-DMTr-2’-FU-methyl phosphonamidite, 5’-O-DMTr-2’-deoxy-2’-fluorouridine-3’-O-(P-methyl-N,N-diisopropylamino) phosphonamidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
    5'-O-DMTr-2'-FU-methyl phosphonamidite

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