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(VI)

" in MedChemExpress (MCE) Product Catalog:

54

Inhibitors & Agonists

1

Fluorescent Dye

2

Biochemical Assay Reagents

2

Peptides

18

Natural
Products

6

Recombinant Proteins

2

Isotope-Labeled Compounds

8

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18623

    Syk Src Cancer
    VI 16832 is a broad spectrum Type I kinase inhibitor which can be used as an enrichment tool for the comparative expression analysis of protein kinases in different cancer cell lines.
    VI 16832
  • HY-N7438

    Others Others
    Mogroside VI A, an isomer of Mogroside VI isolated from Luo Han Guo, exerts sweetness property. Mogroside VI A can be used for sweetener and/or taste modifier research .
    Mogroside VI A
  • HY-E70005I

    Type VI collagenase

    MMP Cancer
    Collagenase, Type VI (EC 3.4.24.3) is a collagenase that can degrade type VI collagen. Type VI collagen is a component of cell membranes in various tissues (such as skin, heart, blood vessels, cartilage, and synovial fluid). Excessive collagenase can cause extracellular matrix lesions. Collagenase is also a biomarker for tumor invasion and metastasis. Collagenase, Type VI can specifically act on the peptide bond between proline and glycine. This feature can be used to quickly and sensitively detect its concentration level in experiments using corresponding modified electrodes .
    Collagenase, Type VI
  • HY-N0265
    Asperosaponin VI
    2 Publications Verification

    Caspase Apoptosis PERK p38 MAPK Akt HIF/HIF Prolyl-Hydroxylase PPAR Cardiovascular Disease Neurological Disease
    Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities .
    Asperosaponin VI
  • HY-162228

    COX Phospholipase Inflammation/Immunology
    VI-60 is a dual, orally active inhibitor of cPLA2 and COX-2, which reveals an anti-inflammtory efficacy through the inhibition of p38 MAPK/cPLA2/COX-2/PGE2 pathway .
    VI-60
  • HY-N14203

    Antibiotic Bacterial Infection
    Maridomycin VI is a macrolide antibiotic. Maridomycin VI has the activity against Gram-positive bacteria and mycoplasma. Maridomycin VI has the effect of protecting Gram-positive bacterial infection mice .
    Maridomycin VI
  • HY-N7527

    Others Neurological Disease
    Baccatin VI is a natural taxoid with antinociceptive activities. Baccatin VI possesses significant antinociceptive activity against p-Benzoquinone-induced abdominal contractions .
    Baccatin VI
  • HY-N0265R

    Reference Standards Caspase Apoptosis PERK Akt p38 MAPK HIF/HIF Prolyl-Hydroxylase PPAR Cardiovascular Disease Neurological Disease
    Asperosaponin VI (Standard) is the analytical standard of Asperosaponin VI. This product is intended for research and analytical applications. Asperosaponin VI is a saponin component from Dipsacus asper. Asperosaponin VI induces osteoblast differentiation through the BMP-2/p38 and ERK1/2 signaling pathways. Asperosaponin VI protects against hypoxia-induced cardiomyocyte apoptosis by activating the PI3K/Akt and CREB pathways. Additionally, Asperosaponin VI also has antidepressant and wound-healing-promoting activities .
    Asperosaponin VI (Standard)
  • HY-N13146

    Others Cardiovascular Disease
    Azukisaponin VI is an oligosaccharide isolated from Vigna angularis. Azukisaponin VI has the activity of inhibiting the synthesis of lipid peroxides and can be used in the study of hyperlipidemia .
    Azukisaponin VI
  • HY-N0816R

    Reference Standards Apoptosis Pyroptosis Cancer
    Polyphyllin VI (Standard) is the analytical standard of Polyphyllin VI. This product is intended for research and analytical applications. Polyphyllin VI, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer .
    Polyphyllin VI (Standard)
  • HY-N5050

    Others Others
    OJV-VI is found in ophiopogonis .
    OJV-VI
  • HY-D1435

    Na+/K+ ATPase Neurological Disease
    Oxonol VI acts as an optical indicator for membrane potentials in lipid vesicles. Oxonol VI is suitable for detecting changes of membrane potential associated with the activity of the (Na + + K +)-ATPase in reconstituted vesicles .
    Oxonol VI
  • HY-137119

    5-iso Prostaglandin F2α-VI

    Prostaglandin Receptor Others
    (±)5-iPF2α-VI (5-iso Prostaglandin F2α-VI) is the racemate of 5-iPF2α-VI. 5-iPF2α-VI is a regioisomeric isoprostane formed from arachidonic acid (AA) and is a biomarker of oxidative stress .
    (±)5-iPF2α-VI
  • HY-N0816
    Polyphyllin VI
    Maximum Cited Publications
    6 Publications Verification

    Apoptosis Pyroptosis Cancer
    Polyphyllin VI, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer .
    Polyphyllin VI
  • HY-118933
    Calpain Inhibitor VI
    1 Publications Verification

    SJA6017

    Proteasome Others
    Calpain Inhibitor VI (SJA6017) is a synthesized peptide aldehyde inhibitor of calpain. Calpain Inhibitor VI inhibits purified m-calpain with the IC50 of 80 nM. Calpain Inhibitor VI can be used for the research of cataract .
    Calpain Inhibitor VI
  • HY-N7439

    PGC-1α Metabolic Disease
    Mogroside VI B, a cucurbitane glucoside, separated from the crude extract of Siraitia grosvenorii. Mogroside VI B shows effect on activating PGC-1α transcription .
    Mogroside VI B
  • HY-N6577

    EGFR Neurological Disease Inflammation/Immunology
    Astragaloside VI could activate EGFR/ERK signalling pathway to improve wound healing.
    Astragaloside VI
  • HY-N7306

    Others Others
    Jatrophane VI is a Diterpenoids product that can be isolated from the herbs of Euphorbia peplus .
    Jatrophane VI
  • HY-155254

    Biochemical Assay Reagents Others
    Sodium ionophore VI is a sodium ionophore that has been employed for developing cation optical sensors .
    Sodium ionophore VI
  • HY-Y0994A

    Biochemical Assay Reagents Others
    Potassium osmate(VI) dihydrate,99% is a biological molecule.
    Potassium osmate(VI) dihydrate,99%
  • HY-108275

    Biochemical Assay Reagents Metabolic Disease Cancer
    Mogroside VI is a triterpenoid glycoside and a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities .
    Mogroside VI
  • HY-N15355

    Others Others
    Jujubasaponin VI is a triterpenoid saponin compound found in Zizyphi Fructus, exhibiting anti-ulcer activity. Animal studies have shown that it can significantly inhibit the formation of stress-induced gastric ulcers, possibly through mechanisms such as protecting the gastric mucosa and suppressing gastric acid secretion. Jujubasaponin VI can be used in research related to digestive system diseases, particularly in the areas of gastric ulcers and gastric mucosal injury .
    Jujubasaponin VI
  • HY-120981S

    Isotope-Labeled Compounds Others
    (±)5-iPF2α-VI-d11 is the deuterium labeled (±)5-iPF2α-VI .
    (±)5-iPF2α-VI-d11
  • HY-137119A

    Prostaglandin Receptor Others
    8,12-iso-iPF2α-VI is a F2-isoprostanes. 8,12-iso-iPF2α-VI is a sensitive and specific marker of in vivo lipid peroxidation. 8,12-iso-iPF2α-VI can be used as a biomarker of oxidative damage in alzheimer's disease .
    8,12-iso-iPF2α-VI
  • HY-137119AS

    Isotope-Labeled Compounds Others
    8,12-iso-iPF2α-VI-d11 is the deuterium labeled 8,12-iso-iPF2α-VI .
    8,12-iso-iPF2α-VI-d11
  • HY-N3991

    Others Others
    14β-Benzoyloxy-2-deacetylbaccatin VI is a xetane-ring-containing taxoid compound isolated from the leaves and stems of Taxus chinensis .
    14β-Benzoyloxy-2-deacetylbaccatin VI
  • HY-E70057

    ST8Sia VI; GD3 synthase

    Endogenous Metabolite Metabolic Disease
    alpha-2,8-Sialyltransferase (CstII) (ST8Sia VI) is a member of alpha2,8-sialyltransferase (ST8Sia) family, is often used in biochemical studies. alpha-2,8-Sialyltransferase (CstII) catalyzes elongation of the α2,8-linked oligo/polysialic acid chain on the Sia residue transferred .
    alpha-2,8-Sialyltransferase (CstII)
  • HY-N14505

    Antibiotic Bacterial Infection
    Mycinamicin VI is a macrolide antibiotic. Mycinamicin VI shows activity against Gram-positive bacteria .
    Mycinamicin Ⅵ
  • HY-143231

    IRAK Infection
    IRAK4-IN-8 (VI-177) is a potent IRAK4 inhibitor .
    IRAK4-IN-8
  • HY-12485R

    Reference Standards Bacterial Antibiotic Infection
    Polyphyllin VI (Standard) is the analytical standard of Polyphyllin VI. This product is intended for research and analytical applications. Polyphyllin VI, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer .
    TBA-354 (Standard)
  • HY-49073

    p38 MAPK Cancer
    p38 MAP Kinase Inhibitor VI (compound c32) is a p38 MAPK inhibitor with an inhibition rate of 24% .
    p38 MAP Kinase Inhibitor Ⅵ
  • HY-W100942

    Biochemical Assay Reagents Others
    Fmoc-D-2-Me-Trp-OH (compound VI) is a polypeptide that can be used as a biochemical assay reagent .
    Fmoc-D-2-Me-Trp-OH
  • HY-N0260
    Epmedin C
    5 Publications Verification

    Epimedin-C; Baohuoside-VI

    Others Inflammation/Immunology
    Epmedin C, a natural product, has estrogen-like effects for ovariectomized mice.
    Epmedin C
  • HY-115912

    Glycoprotein VI Cardiovascular Disease
    GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 3 are, respectively, 1.01 μM for collagen, 1.92 μM for CRP, 7.24 μM for convulxin and 51.74 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 3 is a promising antiplatelet agent .
    GPVI antagonist 3
  • HY-115911

    Glycoprotein VI Cardiovascular Disease
    GPVI antagonist 2 (Compound 1) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 2 are, respectively, 0.35 μM for collagen, 0.80 μM for CRP, 195.2 μM for convulxin and 81.38 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 2 is a promising antiplatelet agent .
    GPVI antagonist 2
  • HY-143755

    Influenza Virus Infection
    Cap-dependent endonuclease-IN-9 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-9 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-9 has strong inhibitory effect on RNA polymerase activity of A virus (extracted from patent CN112521386A, compound VI-1) .
    Cap-dependent endonuclease-IN-9
  • HY-143744

    Influenza Virus Infection
    Cap-dependent endonuclease-IN-3 is a potent inhibitor of cap-dependent endonuclease (CEN). Not only can Cap-dependent endonuclease-IN-3 inhibit influenza virus well, but also has lower cytotoxicity, better in vivo agent kinetic properties and in vivo pharmacodynamic properties. Cap-dependent endonuclease-IN-3 has the potential for the research of influenza A and influenza B infection (extracted from patent WO2019141179A1, compound VI-1) .
    Cap-dependent endonuclease-IN-3
  • HY-Y0319D

    Endogenous Metabolite Others
    Acetic acid lead can provide either acetate radicals or acetoxonium ions. Acetic acid lead may be an acceptable oxidising agent for the preparation of sulphur (VI) systems, as witnessed by its reaction with thiodithiazyl dichloride .
    Acetic acid lead
  • HY-101947
    SMI-16a
    5 Publications Verification

    PIM1/2 Kinase Inhibitor VI

    Pim Cancer
    SMI-16a is a selective Pim kinase inhibitor with IC50 values of 0.15, 0.02 and 48 μM for Pim1, Pim2 and PC3 cells, respectively.
    SMI-16a
  • HY-N0260R

    Epimedin-C (Standard); Baohuoside-VI (Standard)

    Reference Standards Others Inflammation/Immunology
    Epmedin C (Standard) is the analytical standard of Epmedin C. This product is intended for research and analytical applications.
    Epmedin C (Standard)
  • HY-115998

    Carbonic Anhydrase Cancer
    Carbonic anhydrase inhibitor 11 (compound VI) is a potent, selective carbonic anhydrase inhibitor. Carbonic anhydrase inhibitor 11 shows Ki values of 40, 39, 200 and 900 nM against CA II, IX, and XII, respectively .
    Carbonic anhydrase inhibitor 11
  • HY-144390
    (S)-S007-1558
    1 Publications Verification

    GPVI antagonist 1

    Glycoprotein VI Cardiovascular Disease
    (S)-S007-1558 (compound 5) is a glycoprotein VI (GPVI) platelet receptor antagonist. (S)-S007-1558 inhibits collagen-induced platelet aggregation with an IC50 of 25.3 μM .
    (S)-S007-1558
  • HY-100959

    OR-486; 3,5-Dinitropyrocatechol

    COMT Neurological Disease
    3,5-Dinitrocatechol (OR-486) is a potent catechol-O-methyltransferase inhibitor, with an IC50 of 12 nM. 3,5-Dinitrocatechol can be used in the preparation of the molybdenum (VI)- 3,5-Dinitrocatechol complex .
    3,5-Dinitrocatechol
  • HY-133716

    Drug Intermediate Inflammation/Immunology
    Pantoprazole N-oxide (Impurity-VI) is the impurity found during the Pantoprazole (HY-17507) production. Pantoprazole is an inhibitor for proton pump (PPI) that can be used for diseases related to excessive gastric acid, such as gastric ulcers and gastroesophageal reflux disease (GERD) .
    Pantoprazole N-oxide
  • HY-P10949

    Glycoprotein VI Cardiovascular Disease
    Pep-10L peptide is a glycoprotein VI (GPVI) antagonist with Ki values of 180, 225, and 179 μM for CPR, GPO-1, and Type 1 collagen, respectively. Pep-10L peptide has anti-thrombotic effects .
    pep-10L peptide
  • HY-116083

    Endogenous Metabolite Others
    13,14-Dihydro-15-keto-tetranor prostaglandin D2 (Compound VI) is a prostaglandin D2 metabolite. 13,14-Dihydro-15-keto-tetranor prostaglandin D2 as a biomarker can be used to study prostaglandin D2-related diseases .
    13,14-Dihydro-15-keto-tetranor prostaglandin D2
  • HY-109091
    Lanraplenib
    2 Publications Verification

    GS-9876

    Syk Inflammation/Immunology Cancer
    Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib (GS-9876) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans .
    Lanraplenib
  • HY-100959R

    OR-486 (Standard); 3,5-Dinitropyrocatechol (Standard)

    COMT Reference Standards Neurological Disease
    3,5-Dinitrocatechol (Standard) is the analytical standard of 3,5-Dinitrocatechol. This product is intended for research and analytical applications. 3,5-Dinitrocatechol (OR-486) is a potent catechol-O-methyltransferase inhibitor, with an IC50 of 12 nM. 3,5-Dinitrocatechol can be used in the preparation of the molybdenum (VI)- 3,5-Dinitrocatechol complex .
    3,5-Dinitrocatechol (Standard)
  • HY-109091B
    Lanraplenib succinate
    2 Publications Verification

    GS-9876 succinate

    Syk Inflammation/Immunology Cancer
    Lanraplenib succinate (GS-9876 succinate) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib succinate (GS-9876 succinate) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans .
    Lanraplenib succinate
  • HY-109091A

    GS-9876 monosuccinate

    Syk Inflammation/Immunology Cancer
    Lanraplenib monosuccinate (GS-9876 monosuccinate) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib monosuccinate (GS-9876 monosuccinate) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans .
    Lanraplenib monosuccinate

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