2. Academic Validation
  3. Preparation and application of dextran and its derivatives as carriers

Preparation and application of dextran and its derivatives as carriers

  • Int J Biol Macromol. 2020 Feb 15:145:827-834. doi: 10.1016/j.ijbiomac.2019.11.151.
Fang Chen 1,  Gangliang Huang 2,  Hualiang Huang 3
Affiliations

Affiliations

  • 1 Active Carbohydrate Research Institute, Chongqing Key Laboratory of Inorganic Functional Materials, College of Chemistry, Chongqing Normal University, Chongqing 401331, China.
  • 2 Active Carbohydrate Research Institute, Chongqing Key Laboratory of Inorganic Functional Materials, College of Chemistry, Chongqing Normal University, Chongqing 401331, China. Electronic address: huangdoctor226@163.com.
  • 3 School of Chemistry and Environmental Engineering, Wuhan Institute of Technology, Wuhan, 430073, China.
PMID: 31756474 DOI: 10.1016/j.ijbiomac.2019.11.151
Abstract

As a natural and renewable biological macromolecule, dextran not only has excellent biodegradability, but also has good biocompatibility. Dextran and its derivatives are functional Polymers for the construction of targeted drug delivery systems. Herein, the application of dextran as prodrug and nanoparticle/nanogel/microsphere/micelle carrier for targeting drug delivery system was summarized. It is clarified that dextran is an important biomaterial with application value.

Keywords

Dextran; Nanocarrier; Targeted drug delivery.

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