2. Immunology/Inflammation Protein Tyrosine Kinase/RTK PI3K/Akt/mTOR MAPK/ERK Pathway Stem Cell/Wnt Metabolic Enzyme/Protease
  3. Interleukin Related FAK Src Akt ERK MMP
  4. IL13Rα2 D1

IL13Rα2 D1 is an effective IL-13/IL13Rα2 signaling axis inhibitor. IL13Rα2 D1 can inhibit IL-13-induced cell adhesion, migration, invasion, and proliferation. IL13Rα2 D1 can inhibit FAK, Src, AKT, ERK1/2 phosphorylation, and MMP expression. IL13Rα2 D1 can be used for research on cancers such as colorectal cancer.

For research use only. We do not sell to patients.

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IL13Rα2 D1

IL13Rα2 D1 Chemical Structure

CAS No. : 2319573-67-4

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IL13Rα2 D1 Related Antibodies

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

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Lck Fyn Blk Fgr Hck Lyn Yes SRC-3

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Akt Akt1 Akt2 Akt3

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ERK ERK1 ERK2 ERK5 ERK8

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MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8

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Description

IL13Rα2 D1 is an effective IL-13/IL13Rα2 signaling axis inhibitor. IL13Rα2 D1 can inhibit IL-13-induced cell adhesion, migration, invasion, and proliferation. IL13Rα2 D1 can inhibit FAK, Src, AKT, ERK1/2 phosphorylation, and MMP expression. IL13Rα2 D1 can be used for research on cancers such as colorectal cancer[1].

IC50 & Target[1]

IL-13

 

Molecular Weight

1377.54

Formula

C61H100N16O20
CAS No.
Sequence

Gly-Ser-Glu-Thr-Trp-Lys-Thr-Ile-Ile-Thr-Lys-Asn
Sequence Shortening

GSETWKTIITKN
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IL13Rα2 D1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IL13Rα2 D12319573-67-4Interleukin RelatedFAKSrcAktERKMMPILPTK2 protein tyrosine kinase 2PTK2Focal adhesion kinasePKBProtein kinase BExtracellular signal regulated kinasesMatrix metalloproteinasesIL-13IL13Rα2AKTERK1/2colorectal cancerInhibitorinhibitorinhibit

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