2. Anti-infection Metabolic Enzyme/Protease
  3. HIV Protease HIV
  4. HIV-1-IN-88

HIV-1-IN-88 (compound 20a) is a potent HIV‑1 protease inhibitor (IC50 = 10 pM) with an antiviral EC50 of 10.4 nM. HIV-1-IN-88 exhibits potency against the multidrug-resistant variants HIV-1Muta and HIV-1I50V with EC50 values of 30.0 and 34.3 nM, respectively. HIV-1-IN-88 can be used for HIV research.

For research use only. We do not sell to patients.

HIV-1-IN-88

HIV-1-IN-88 Chemical Structure

CAS No. : 2459707-59-4

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HIV-1-IN-88 Related Antibodies

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Description

HIV-1-IN-88 (compound 20a) is a potent HIV‑1 protease inhibitor (IC50 = 10 pM) with an antiviral EC50 of 10.4 nM. HIV-1-IN-88 exhibits potency against the multidrug-resistant variants HIV-1Muta and HIV-1I50V with EC50 values of 30.0 and 34.3 nM, respectively. HIV-1-IN-88 can be used for HIV research[1].

IC50 & Target[1]

HIV‑1 protease

10 pM (IC50)

Molecular Weight

676.78

Formula

C32H44N4O10S
CAS No.
SMILES

O[C@@H]([C@@H](NC([C@H](CC(N)=O)NC(O[C@@]1([C@]2([C@@]([H])(OC1)OCC2)[H])[H])=O)=O)CC3=CC=CC=C3)CN(CC(C)C)S(=O)(C4=CC=C(C=C4)OC)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HIV-1-IN-88 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HIV-1-IN-882459707-59-4HIV ProteaseHIVHuman immunodeficiency virusHIV?1 proteasemultidrug-resistant variantsHIV-1MutaHIV-1I50VInhibitorinhibitorinhibit

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