2. Disease Areas
  3. Infection
  4. HIV Infection

HIV Infection

Acute HIV infection is a self-limited phase occurring within the first few weeks after initial exposure to the human immunodeficiency virus (HIV), marked by rapid viral replication, high viral loads, and nonspecific symptoms such as fever, rash, and lymphadenopathy. This stage may last from days to over 10 weeks, during which the immune system begins to mount a response. Early diagnosis is critical for initiating timely treatment and reducing transmission risk. HIV infection is associated with acquired immunodeficiency syndrome (AIDS) and has links to other infectious diseases like syphilis. The CCR5 gene plays a key role in HIV pathogenesis, and related biological pathways include the Innate Immune System and ERK Signaling. Drugs such as Candesartan cilexetil and Lercanidipine have been studied in this context. Affected tissues include T cells and breast tissue, with associated phenotypes involving cellular dysfunction and neoplastic changes.

 

HIV Infection (1):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-178923
    NNRT-IN-14
    NNRT-IN-14 is an HIV-1 reverse transcriptase inhibitor (IC50 = 0.175 µM). NNRT-IN-14 can form hydrogen bonds with LYS101, PRO225, and PHE227, and π–π stacking with TYR181 and TRP229. NNRT-IN-14 can be used for the study of HIV.
    NNRT-IN-14