2. Anti-infection
  3. HIV Reverse Transcriptase
  4. HIV-1-IN-83

HIV-1-IN-83 (Compound 18E) is a HIV-1 non-nucleoside reverse transcriptase inhibitor with an IC50 of 0.45 μM for wild-type HIV-1 non-nucleoside reverse transcriptase. HIV-1-IN-83 has potent antiviral activity against both HIV-1 wild-type and mutant strains and improves antidrug resistance for Y188L and RES056 mutant strains. HIV-1-IN-83 has no significant toxicity up to 11.088 μM.

For research use only. We do not sell to patients.

HIV-1-IN-83

HIV-1-IN-83 Chemical Structure

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HIV-1-IN-83 Related Antibodies

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Description

HIV-1-IN-83 (Compound 18E) is a HIV-1 non-nucleoside reverse transcriptase inhibitor with an IC50 of 0.45 μM for wild-type HIV-1 non-nucleoside reverse transcriptase. HIV-1-IN-83 has potent antiviral activity against both HIV-1 wild-type and mutant strains and improves antidrug resistance for Y188L and RES056 mutant strains. HIV-1-IN-83 has no significant toxicity up to 11.088 μM[1].

Molecular Weight

668.79

Formula

C33H32N8O4S2
SMILES

CC1=CC(C2=NN=C(O2)C3=CN=CC=C3)=CC(C)=C1OC4=C5SC=CC5=NC(NC6CCN(CC6)CC7=CC=C(C=C7)S(=O)(N)=O)=N4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HIV-1-IN-83 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HIV-1-IN-83HIVReverse TranscriptaseHuman immunodeficiency virusInhibitorAntiviralHIV-1Non-nucleoside reverse transcriptaseMT-4 cellsY188LRES056inhibitorinhibit

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