2. Gene
  3. Cdk9 - cyclin-dependent kinase 9 Gene

Cdk9 - cyclin-dependent kinase 9 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 362110 | Gene type: protein coding

About Cdk9

Biased expression in Spleen (RPKM 124.8), Thymus (RPKM 121.4) and 9 other tissues.

Summary

Enables chromatin binding activity. Involved in positive regulation of cardiac muscle hypertrophy and response to xenobiotic stimulus. Located in nucleus. Orthologous to human CDK/cdk9.html" target="_blank" style="color: #6a4b92; font-weight:bold;">CDK9 (cdk1.html" target="_blank" style="color: #6a4b92; font-weight:bold;">cyclin dependent kinase 9). [provided by Alliance of Genome Resources, Apr 2022]

Cdk9 Products(1)

mRNA Protein Name
NM_001007743.1 NP_001007744.1 cyclin-dependent kinase 9
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables chromatin binding IDA
IDA: Inferred from direct assay
20081228 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of cardiac muscle hypertrophy IMP
IMP: Inferred from mutant phenotype
20081228 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
20828602 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Cdk9 Protein Structure

STKc_CDK9

STKc_CDK9: cd07865 (5 - 314)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase 9

cell division protein kinase 9

cyclin-dependent kinase 9 (CDC2-related kinase)

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16297A Abemaciclib Inhibitor 99.97% Yes
HY-10492 Dinaciclib Inhibitor 99.64% Yes
HY-16297 Abemaciclib methanesulfonate Inhibitor 99.95% Yes
Clinical Phase
Bioactive Molecules (22)
Cat. No. Product Name Effect
Purity Phase
HY-112272 Lerociclib Inhibitor 98.35% Phase 3
HY-112088 AZD4573 Inhibitor 99.98% Phase 2
HY-103712A Samuraciclib hydrochloride Inhibitor 99.98% Phase 2
HY-50940 AT7519 Inhibitor 99.76% Phase 2
HY-137478A KB-0742 dihydrochloride Inhibitor 99.24% Phase 2
HY-101212 Fadraciclib Inhibitor 99.78% Phase 2
HY-112272A Lerociclib dihydrochloride Inhibitor 98.11% Phase 2
HY-103712B Samuraciclib hydrochloride dihydrate Inhibitor 99.08% Phase 2
HY-50943 AT7519 Hydrochloride Inhibitor 99.42% Phase 2
HY-103712C Samuraciclib hydrochloride hydrate Inhibitor 99.88% Phase 2
HY-50940A AT7519 TFA Inhibitor 96.62% Phase 2
HY-103712 Samuraciclib Inhibitor / Phase 2
HY-16559A Riviciclib Inhibitor / Phase 2
HY-10008 SNS-032 Inhibitor 99.54% Phase 1
HY-138293 SY-5609 Inhibitor 99.33% Phase 1
HY-10012 AZD-5438 Inhibitor 99.91% Phase 1
HY-12871B Atuveciclib Inhibitor 99.80% Phase 1
HY-11001 PHA-793887 Inhibitor 99.25% Phase 1
HY-15504 RGB-286638 Inhibitor 99.70% Phase 1
HY-12422 Voruciclib Inhibitor 99.77% Phase 1
HY-15504A RGB-286638 free base Inhibitor 98.07% Phase 1
HY-12422A Voruciclib hydrochloride Inhibitor 99.23% Phase 1
Pre-clinical Phase
Bioactive Molecules (115)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103618 THZ531 Inhibitor 99.86% Unkown
HY-103248 Toyocamycin Inhibitor 99.78% Unkown
HY-12214A NVP-2 Inhibitor 99.60% Unkown
HY-103019 (+)-Enitociclib Inhibitor 99.89% Unkown
HY-18340 (R)​-​CR8 Inhibitor 99.61% Unkown
HY-101257 YKL-5-124 Inhibitor 98.79% Unkown
HY-123954 BTX-A51 Inhibitor 98.58% Unkown
HY-130665 TL12-186 Inhibitor 99.63% Unkown
HY-111388A Romaciclib monohydrochloride Inhibitor 99.29% Unkown
HY-11009 CGP60474 Inhibitor 99.23% Unkown
HY-130709 PROTAC CDK2/9 Degrader-1 Inhibitor 99.85% Unkown
HY-13461A PHA-767491 hydrochloride Inhibitor 99.49% Unkown
HY-13914 Roniciclib Inhibitor 98.09% Unkown
HY-15878 LDC000067 Inhibitor 99.00% Unkown
HY-12445 Asnuciclib Inhibitor 99.76% Unkown
HY-13266A BS-181 hydrochloride Inhibitor 99.80% Unkown
HY-12280 THZ2 Inhibitor 99.03% Unkown
HY-18340A (R)-CR8 trihydrochloride Inhibitor 98.95% Unkown
HY-X0150 JSH-150 Inhibitor 98.66% Unkown
HY-144117 GFB-12811 Inhibitor 98.04% Unkown
HY-119940 MC180295 Inhibitor 98.89% Unkown
HY-103628 PROTAC CDK9 Degrader-1 Inhibitor 98.03% Unkown
HY-12293 LY2857785 Inhibitor 99.92% Unkown
HY-111388B SEL120-34A hydrochloride Inhibitor 99.98% Unkown
HY-112626 CDK12-IN-2 Inhibitor 99.36% Unkown
HY-16559 Riviciclib hydrochloride 99.08% Unkown
HY-143584 AZ5576 Inhibitor 99.88% Unkown
HY-117203A CDK12-IN-E9 Inhibitor 99.97% Unkown
HY-13231 CDK9-IN-1 Inhibitor 98.52% Unkown
HY-X0009 Tambiciclib Inhibitor 99.21% Unkown
HY-16462 CDK9-IN-2 Inhibitor 99.37% Unkown
HY-101257B YKL-5-124 TFA Inhibitor 99.74% Unkown
HY-103019B (-)-Enitociclib Inhibitor 99.85% Unkown
HY-13033 CDK-IN-2 Inhibitor 98.97% Unkown
HY-18944 FIT-039 Inhibitor 99.56% Unkown
HY-124639 CDK9 inhibitor HH1 Inhibitor 99.56% Unkown
HY-137478 KB-0742 Inhibitor 99.38% Unkown
HY-126251 CDK9-IN-7 Inhibitor 98.05% Unkown
HY-12871 Atuveciclib Racemate Inhibitor 98.48% Unkown
HY-139980 CDK9-IN-13 Inhibitor 99.94% Unkown
HY-153260 TP-1287 Inhibitor 95.10% Unkown
HY-123955 Casein Kinase inhibitor A86 Inhibitor 99.26% Unkown
HY-103646 CK7 Inhibitor 99.72% Unkown
HY-153556 GW297361 Inhibitor 98.13% Unkown
HY-15241 NVP-LCQ195 Inhibitor 98.81% Unkown
HY-100429 CAN508 Inhibitor 99.59% Unkown
HY-102039 CDK9-IN-8 Inhibitor 99.65% Unkown
HY-100950 ABC1183 Inhibitor 99.19% Unkown
HY-130852 CDK9-IN-11 Inhibitor 97.02% Unkown
HY-111427 CDK8/19-IN-1 Inhibitor 98.03% Unkown
HY-139328 CDK12-IN-5 Inhibitor 99.01% Unkown
HY-13461 PHA-767491 Inhibitor 99.85% Unkown
HY-162037 CDDD11-8 Inhibitor 99.62% Unkown
HY-115714 CDK9-IN-12 Inhibitor 99.65% Unkown
HY-130850 CDK9-IN-10 Inhibitor 98.09% Unkown
HY-143585 CDK9-IN-14 Inhibitor 99.91% Unkown
HY-151069 TMX-2039 Inhibitor 99.42% Unkown
HY-14372 BS-194 Inhibitor 99.36% Unkown
HY-13266 BS-181 Inhibitor 98.10% Unkown
HY-168518 PROTAC CDK9 degrader-9 Degrader 98.09% Unkown
HY-139329 CDK12-IN-6 Inhibitor 98.09% Unkown
HY-12843 Bohemine Inhibitor 98.93% Unkown
HY-112811 PROTAC CDK9 degrader-2 Inhibitor / Unkown
HY-111388 SEL120-34A Inhibitor / Unkown
HY-X0009A JSH-009 dimaleate Inhibitor / Unkown
HY-110368 BS-181 dihydrochloride Inhibitor / Unkown
HY-151436 ZLMT-12 Inhibitor / Unkown
HY-130001 CDK9-IN-9 Inhibitor / Unkown
HY-130981 FN-1501-propionic acid / Unkown
HY-131063 CDK6/9-IN-1 Inhibitor / Unkown
HY-164906 TMX-2138 Degrader / Unkown
HY-156083 CDK9-IN-28 Inhibitor / Unkown
HY-153426 CDK9-IN-23 Inhibitor / Unkown
HY-168896 CDK9 autophagic degrader 1 Degrader / Unkown
HY-119715 AG-012986 Inhibitor / Unkown
HY-161379 CLZX-205 Inhibitor / Unkown
HY-151878 CDK7-IN-20 Inhibitor / Unkown
HY-161595 CDK5-IN-4 Inhibitor / Unkown
HY-139327 CDK12-IN-4 Inhibitor / Unkown
HY-123034 CDKI-83 Inhibitor / Unkown
HY-145408 CDK7/9-IN-1 Inhibitor / Unkown
HY-150562 CDK9-IN-19 Inhibitor / Unkown
HY-170942 CDK9/PARP-IN-1 Inhibitor / Unkown
HY-147771 ZLWT-37 Inhibitor / Unkown
HY-168845 CDK2/9-IN-1 Inhibitor / Unkown
HY-169244 CDK-TCIP1 Inhibitor / Unkown
HY-149962 PROTAC CDK9 degrader-5 Inhibitor / Unkown
HY-136841 SLM6 Inhibitor / Unkown
HY-150641 CDK-IN-9 Inhibitor / Unkown
HY-149495 CP-07 Degrader / Unkown
HY-173348 BLINK15 Inhibitor / Unkown
HY-111356 IIIM-290 Inhibitor / Unkown
HY-155153 CDK9-IN-24 Inhibitor / Unkown
HY-173347 BLINK11 Inhibitor / Unkown
HY-163856 CDK7-IN-30 Inhibitor / Unkown
HY-161463 CDK2-IN-28 Inhibitor / Unkown
HY-161768 VCC972839:01 Inhibitor / Unkown
HY-151898 CDK4/6-IN-14 Inhibitor / Unkown
HY-156795 PROTAC CDK9/CycT1 Degrader-2 Inhibitor / Unkown
HY-155787 SHR5428 Inhibitor / Unkown
HY-162706 BSJ-5-63 Degrader 99.97% Unkown
HY-151984 CDK9-IN-22 Inhibitor / Unkown
HY-150573 CDK2-IN-12 Inhibitor / Unkown
HY-149963 PROTAC CDK9 degrader-6 Inhibitor / Unkown
HY-157980 CDK9-IN-32 Inhibitor / Unkown
HY-142696 CDK6/PIM1-IN-1 Inhibitor / Unkown
HY-162619 CDK9-IN-33 Inhibitor / Unkown
HY-173065 CDK9-IN-36 Inhibitor / Unkown
HY-170815 CDK4/9-IN-1 Inhibitor / Unkown
HY-149870 PROTAC CDK9 degrader-8 Inhibitor / Unkown
HY-112403 (S)-Roscovitine Inhibitor / Unkown
HY-112450 Olomoucine II Inhibitor / Unkown
HY-164619 CDK9-IN-34 Inhibitor / Unkown
HY-119120 JTK-101 Inhibitor / Unkown
HY-123826 CCT68127 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdk9 NCBI NCBI:1025