Syt3 - synaptotagmin III Gene

Mus musculus

Also known as sytIII

Gene ID: 20981 | Gene type: protein coding

About Syt3

Summary

Enables calcium-dependent phospholipid binding activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in several processes, including positive regulation of dendrite extension; regulation of dopamine secretion; and regulation of vesicle-mediated transport. Predicted to act upstream of or within cell differentiation and exocytosis. Predicted to be located in endosome. Predicted to be active in exocytic vesicle and plasma membrane. Is expressed in several structures, including eye; genitourinary system; heart; nervous system; and respiratory system. Orthologous to human SYT3 (synaptotagmin 3). [provided by Alliance of Genome Resources, Apr 2022]

Syt3 Products(2)

mRNA	Protein	Name
NM_001114116.1	NP_001107588.1	synaptotagmin-3
NM_016663.3	NP_057872.3	synaptotagmin-3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables calcium-dependent phospholipid binding	IDA IDA: Inferred from direct assay	8626542	MGI
enables identical protein binding	IPI IPI: Inferred from physical interaction	10531343	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	10531343	MGI
enables protein heterodimerization activity	IPI IPI: Inferred from physical interaction	20002670	MGI
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	10531343	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in regulation of postsynaptic membrane neurotransmitter receptor levels	IDA IDA: Inferred from direct assay	30545844	MGI
involved in regulation of postsynaptic membrane neurotransmitter receptor levels	IMP IMP: Inferred from mutant phenotype	30545844	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in postsynapse	IDA IDA: Inferred from direct assay	30545844	MGI
is active in postsynapse	IEP IEP: Inferred from expression pattern	30545844	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

synaptotagmin-3

Syt3 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Syt3	O35681	Syt10	Mus musculus	Q9R0N4	Comigration in SDS	10531343
Intra	Syt3	O35681	Syt9	Mus musculus	Q9R0N9	Comigration in SDS	10531343
Intra	Syt3	O35681	Syt3	Mus musculus	O35681	Comigration in SDS	10531343
Intra	Syt3	O35681	Syt6	Mus musculus	Q9R0N8	Comigration in SDS	10531343

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14115	SYT3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Syt3	NCBI	NCBI:84258

Name
Email *

	Sorry, but the email address you supplied was invalid.