Nrbp1 - nuclear receptor binding protein 1 Gene

Mus musculus

Also known as Nrbp; B230344L17Rik

Gene ID: 192292 | Gene type: protein coding

About Nrbp1

Summary

Enables protein homodimerization activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intracellular signal transduction. Located in perinuclear region of cytoplasm. Is expressed in cap mesenchyme; ovary; and renal interstitium. Orthologous to human NRBP1 (nuclear receptor binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Nrbp1 Products(2)

mRNA	Protein	Name
NM_001347326.1	NP_001334255.1	nuclear receptor-binding protein isoform 1
NM_147201.2	NP_671734.1	nuclear receptor-binding protein isoform 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
NOT enables ATP binding	IDA IDA: Inferred from direct assay	12176995	MGI
enables identical protein binding	IPI IPI: Inferred from physical interaction	12176995	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	12176995	MGI
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	12176995	MGI
NOT enables protein kinase activity	IDA IDA: Inferred from direct assay	12176995	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in epithelial cell differentiation	IMP IMP: Inferred from mutant phenotype	22510880	MGI
involved in epithelial cell proliferation	IMP IMP: Inferred from mutant phenotype	22510880	MGI
involved in in utero embryonic development	IMP IMP: Inferred from mutant phenotype	22510880	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	12176995	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

nuclear receptor-binding protein

HLS7-interacting protein kinase

MLF1 adapter molecule

Nrbp1 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	Nrbp1	Q99J45	Mlf1	Mus musculus	Q9QWV4	Y2H	12176995
Intra	Nrbp1	Q99J45	Nrbp1	Mus musculus	Q99J45	Y2H	12176995
Intra	Nrbp1	Q99J45	MLF1	Homo sapiens	P58340	Y2H	12176995
Intra	Nrbp1	Q99J45	Nrbp1	Mus musculus	Q99J45	Anti Tag CoIP	12176995

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09562	NRBP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Nrbp1	NCBI	NCBI:29959

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