2. Gene
  3. Aip - aryl-hydrocarbon receptor-interacting protein Gene

Aip - aryl-hydrocarbon receptor-interacting protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ara9; Xap2; Fkbp16; D19Bwg1412e

Gene ID: 11632 | Gene type: protein coding

About Aip

Summary

This gene encodes an Hsp90-associated protein that is localized to the cytoplasm. The encoded protein interacts with the Aryl Hydrocarbon Receptor (AhR) and the tyrosine kinase receptor RET, inhibits AhR ubiquitination, and regulates the intracellular localization of AhR. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Aip Products(4)

mRNA Protein Name
NM_001276284.2 NP_001263213.1 AH receptor-interacting protein
NM_001409753.1 NP_001396682.1 AH receptor-interacting protein
NM_001409754.1 NP_001396683.1 AH receptor-interacting protein
NM_016666.4 NP_057875.1 AH receptor-interacting protein
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables aryl hydrocarbon receptor binding IPI
IPI: Inferred from physical interaction
9083006 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15082773 MGI
enables transcription coregulator activity IPI
IPI: Inferred from physical interaction
9083006 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within xenobiotic metabolic process IPI
IPI: Inferred from physical interaction
9083006 MGI
Cellular Component GO Annotation Evidence Reference Source
part of aryl hydrocarbon receptor complex IDA
IDA: Inferred from direct assay
9083006 MGI
located in cytosol IDA
IDA: Inferred from direct assay
9083006 MGI
located in membrane IDA
IDA: Inferred from direct assay
15082773 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

AH receptor-interacting protein

Aip Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Aip O08915 Gna13 Mus musculus P27601
Pull Down
19390533
Intra
Aip O08915 Gnaq Mus musculus P21279
Pull Down
19390533
Intra
Aip O08915 Gnaq Mus musculus P21279
Anti Tag CoIP
19390533
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P10486 AIP-II Inhibitor / Unkown
HY-RS00499 AIP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01269 AURKAIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02415 CDKN2AIP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04442 EPM2AIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14904 TOR1AIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14905 TOR1AIP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14914 TP53AIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17392 Aip Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23847 Aip Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aip NCBI NCBI:9049
Rattus norvegicus Aip NCBI NCBI:282827