2. Gene
  3. Aip - aryl-hydrocarbon receptor-interacting protein Gene

Aip - aryl-hydrocarbon receptor-interacting protein Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as XAP2

Gene ID: 282827 | Gene type: protein coding

About Aip

Summary

Predicted to enable several functions, including GAF domain binding activity; Aryl Hydrocarbon Receptor binding activity; and unfolded protein binding activity. Involved in negative regulation of cyclic-nucleotide phosphodiesterase activity and regulation of protein kinase A signaling. Located in cytosol. Human ortholog(s) of this gene implicated in pituitary adenoma 1. Orthologous to human AIP (Aryl Hydrocarbon Receptor interacting protein). [provided by Alliance of Genome Resources, Apr 2022]

Aip Products(1)

mRNA Protein Name
NM_172327.3 NP_758830.2 AH receptor-interacting protein
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
12810716 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
17329248 RGD
Biological Process GO Annotation Evidence Reference Source
involved in protein kinase A signaling IDA
IDA: Inferred from direct assay
12810716 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

AH receptor-interacting protein

HBV-X associated protein

immunophilin XAP2

Aip Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Aip Q5FWY5 Pde2a Rattus norvegicus Q01062
Anti Bait CoIP
17329248
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P10486 AIP-II Inhibitor / Unkown
HY-RS00499 AIP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS02415 CDKN2AIP Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04442 EPM2AIP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14904 TOR1AIP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14905 TOR1AIP2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS14914 TP53AIP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17392 Aip Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23847 Aip Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aip NCBI NCBI:9049
Mus musculus Aip NCBI NCBI:11632