FGFR2 - fibroblast growth factor receptor 2 Gene

Oryctolagus cuniculus

Gene ID: 100009417 | Gene type: protein coding

About FGFR2

Chromosome 18: 68,468,927-68,572,794 reverse strand.OryCun2.0:CM000807.1

This gene has 10 transcripts (splice variants), 221 orthologues and 56 paralogues.

mRNA	Protein	Name
NM_001082688.1	NP_001076157.1	fibroblast growth factor receptor 2 precursor

IgI_2_FGFR

PTKc_FGFR2

Protein Preferred Names

Protein Names

fibroblast growth factor receptor 2

Approval

Bioactive Molecules (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-10981	Lenvatinib	Inhibitor	99.84%	Yes
HY-50904	Nintedanib	Inhibitor	99.94%	Yes
HY-18708	Erdafitinib	Inhibitor	99.66%	Unkown
HY-13311	Infigratinib	Inhibitor	99.72%	Yes
HY-109099	Pemigatinib	Inhibitor	99.84%	Yes
HY-100818	Futibatinib	Inhibitor	99.65%	Unkown
HY-11106	Nintedanib esylate	Inhibitor	99.95%	Yes
HY-10981A	Lenvatinib mesylate	Inhibitor	99.86%	Yes
HY-N0060	Ferulic acid	Inhibitor	99.87%	Yes
HY-13311A	Infigratinib phosphate	Inhibitor	99.74%	Yes

Clinical Phase

Bioactive Molecules (17)

Cat. No.	Product Name	Effect	Purity	Phase
HY-13330	Fexagratinib	Inhibitor	99.85%	Phase 3
HY-100019	Rogaratinib	Inhibitor	99.86%	Phase 3
HY-15391	Lucitanib	Inhibitor	98.94%	Phase 3
HY-101568	Roblitinib	Inhibitor	99.74%	Phase 2
HY-13034	Gandotinib	Inhibitor	99.82%	Phase 2
HY-10987A	ENMD-2076	Inhibitor	99.12%	Phase 2
HY-19957	Zoligratinib	Inhibitor	99.76%	Phase 2
HY-19981	Derazantinib	Inhibitor	99.28%	Phase 2
HY-10987	ENMD-2076 Tartrate	Inhibitor	99.42%	Phase 2
HY-10186	TG 100801	Inhibitor	98.61%	Phase 2
HY-101466A	E7090 succinate	Inhibitor	99.17%	Phase 2
HY-10187	TG 100801 Hydrochloride	Inhibitor	/	Phase 2
HY-13304	LY2874455	Inhibitor	98.03%	Phase 1
HY-119367	ODM-203	Inhibitor	99.91%	Phase 1
HY-19983	ASP5878	Inhibitor	99.69%	Phase 1
HY-101768	PRN1371	Inhibitor	99.43%	Phase 1
HY-100491	H3B-6527	Inhibitor	≥98.0%	Phase 1

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99007	Aprutumab	Inhibitor	96.50%	Phase 1

Pre-clinical Phase

Bioactive Molecules (35)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-N0183	Formononetin	Inhibitor	99.92%	Unkown
HY-12823	BLU9931	Inhibitor	99.95%	Unkown
HY-147250	Lirafugratinib	Inhibitor	99.60%	Unkown
HY-122704A	Surfen dihydrochloride	Inhibitor	≥99.0%	Unkown
HY-17601	Alofanib	Inhibitor	99.90%	Unkown
HY-15599	SSR128129E	Inhibitor	99.85%	Unkown
HY-18602	FIIN-2	Inhibitor	99.63%	Unkown
HY-145231	FGFR2-IN-2	Inhibitor	98.09%	Unkown
HY-147250A	Lirafugratinib hydrochloride	Inhibitor	98.73%	Unkown
HY-10185	TG 100572 Hydrochloride	Inhibitor	98.96%	Unkown
HY-148779	FGFR3-IN-5	Inhibitor	99.28%	Unkown
HY-101466	E7090	Inhibitor	99.64%	Unkown
HY-131908	CPL304110	Inhibitor	99.68%	Unkown
HY-15813	FIIN-1	Inhibitor	99.11%	Unkown
HY-12965	S49076	Inhibitor	99.44%	Unkown
HY-149843	LC-MB12	Inhibitor	99.23%	Unkown
HY-18603	FIIN-3	Inhibitor	99.66%	Unkown
HY-131704	FGFR4-IN-5	Inhibitor	98.03%	Unkown
HY-10184	TG 100572	Inhibitor	/	Unkown
HY-141685	3-Methylthienyl-carbonyl-JNJ-7706621	Inhibitor	/	Unkown
HY-101544	ARQ 069	Inhibitor	/	Unkown
HY-N9507	Picrasidine Q	Inhibitor	/	Unkown
HY-148597	FGFR-IN-10	Inhibitor	/	Unkown
HY-151903S	FGFR2/3-IN-1	Inhibitor	/	Unkown
HY-142921	FGFR-IN-2	Inhibitor	/	Unkown
HY-147713	FGFR3-IN-1	Inhibitor	/	Unkown
HY-147715	FGFR3-IN-3	Inhibitor	/	Unkown
HY-152146	HDAC-IN-50	Inhibitor	/	Unkown
HY-155028	FGFR-IN-11	Inhibitor	/	Unkown
HY-145230	FGFR2-IN-1	Inhibitor	99.78%	Unkown
HY-158248	FGFR4-IN-19	Inhibitor	/	Unkown
HY-150652	FGFR-IN-8	Inhibitor	/	Unkown
HY-162626	FGFR2 degrader 1	Degrader	/	Unkown
HY-152104	FGFR-IN-9	Inhibitor	/	Unkown
HY-15599A	SSR128129E free acid	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	FGFR2	NCBI	NCBI:2263

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