2. Signaling Pathways
  3. Epigenetics
  4. Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA) is a small exogenous double-stranded RNA (dsRNA) (20-25 nucleotides), which triggers the RNA interference (RNAi) pathway. The short dsRNA unwinds and the sense strand is degraded. Antisense strand forms RNA induced silencing complex (RISC) with various protein components. The antisense strand retained in RISC is specifically complementary to the target gene mRNA. Meanwhile, RISC has nuclease activity, which can cut and degrade the target gene mRNA, and inhibit the expression of target gene. Incomplete complementarity results in mRNA translation inhibition.

Small Interfering RNA (siRNA) Related Products (29531):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-153492A
    Olpasiran sodium
    		Inhibitor 98.82%
    Olpasiran sodium is a small interfering RNA that reduces lipoprotein(a) synthesis in the liver.
    Olpasiran sodium
  • HY-RS09092
    NCOA4 Human Pre-designed siRNA Set A
    		Pre-designed Set

    NCOA4 Human Pre-designed siRNA Set A contains three designed siRNAs for NCOA4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    NCOA4 Human Pre-designed siRNA Set A
  • HY-RS05767
    GPX4 Human Pre-designed siRNA Set A
    		Pre-designed Set

    GPX4 Human Pre-designed siRNA Set A contains three designed siRNAs for GPX4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    GPX4 Human Pre-designed siRNA Set A
  • HY-RS04818
    FBXW7 Human Pre-designed siRNA Set A
    		Pre-designed Set

    FBXW7 Human Pre-designed siRNA Set A contains three designed siRNAs for FBXW7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    FBXW7 Human Pre-designed siRNA Set A
  • HY-RS10376
    PGAM5 Human Pre-designed siRNA Set A
    		Pre-designed Set

    PGAM5 Human Pre-designed siRNA Set A contains three designed siRNAs for PGAM5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    PGAM5 Human Pre-designed siRNA Set A
  • HY-RS13886
    STAT1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    STAT1 Human Pre-designed siRNA Set A contains three designed siRNAs for STAT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    STAT1 Human Pre-designed siRNA Set A
  • HY-RS06249
    HMOX1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    HMOX1 Human Pre-designed siRNA Set A contains three designed siRNAs for HMOX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    HMOX1 Human Pre-designed siRNA Set A
  • HY-RS05069
    FOXO1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    FOXO1 Human Pre-designed siRNA Set A contains three designed siRNAs for FOXO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    FOXO1 Human Pre-designed siRNA Set A
  • HY-RS12352
    RUNX3 Human Pre-designed siRNA Set A
    		Pre-designed Set

    RUNX3 Human Pre-designed siRNA Set A contains three designed siRNAs for RUNX3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    RUNX3 Human Pre-designed siRNA Set A
  • HY-RS00028
    AARS1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    AARS1 Human Pre-designed siRNA Set A contains three designed siRNAs for AARS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    AARS1 Human Pre-designed siRNA Set A
  • HY-RS04409
    EPAS1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    EPAS1 Human Pre-designed siRNA Set A contains three designed siRNAs for EPAS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    EPAS1 Human Pre-designed siRNA Set A
  • HY-173432
    LIBX-A401
    		99.9%
    LIBX-A401 is an inhibitor of long-chain acyl-CoA synthetase 4 (ACSL4) (IC50 = 0.38 μM). LIBX-A401 has selectivity for ACSL4 over ACSL3 (IC50 over 50 μM) and PPARγ (IC50 over 10 μM).
    LIBX-A401
  • HY-RS07584
    LEF1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    LEF1 Human Pre-designed siRNA Set A contains three designed siRNAs for LEF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    LEF1 Human Pre-designed siRNA Set A
  • HY-RS14912
    TP53 Human Pre-designed siRNA Set A
    		Pre-designed Set

    TP53 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    TP53 Human Pre-designed siRNA Set A
  • HY-RS12940
    SIRT2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    SIRT2 Human Pre-designed siRNA Set A contains three designed siRNAs for SIRT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    SIRT2 Human Pre-designed siRNA Set A
  • HY-RS03122
    CPT1A Human Pre-designed siRNA Set A
    		Pre-designed Set

    CPT1A Human Pre-designed siRNA Set A contains three designed siRNAs for CPT1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CPT1A Human Pre-designed siRNA Set A
  • HY-RS02576
    CGAS Human Pre-designed siRNA Set A
    		Pre-designed Set

    CGAS Human Pre-designed siRNA Set A contains three designed siRNAs for CGAS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CGAS Human Pre-designed siRNA Set A
  • HY-RS04289
    EIF6 Human Pre-designed siRNA Set A
    		Pre-designed Set

    EIF6 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    EIF6 Human Pre-designed siRNA Set A
  • HY-RS15003
    TREM2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    TREM2 Human Pre-designed siRNA Set A contains three designed siRNAs for TREM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    TREM2 Human Pre-designed siRNA Set A
  • HY-RS00034
    AATF Human Pre-designed siRNA Set A
    		Pre-designed Set

    AATF Human Pre-designed siRNA Set A contains three designed siRNAs for AATF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    AATF Human Pre-designed siRNA Set A