2. Signaling Pathways
  3. Epigenetics
  4. Small Interfering RNA (siRNA)
  5. Small Interfering RNA (siRNA) Inhibitor

Small Interfering RNA (siRNA) Inhibitor

Small Interfering RNA (siRNA) Inhibitors (10):

Cat. No. Product Name Effect Purity
  • HY-147425A
    Zerlasiran sodium
    		Inhibitor
    Zerlasiran sodium is an apolipoprotein A (ApoA) synthesis reducer.
  • HY-132590A
    Revusiran sodium
    		Inhibitor
    Revusiran sodium is a 1st-generation short interfering RNA, which directed against transthyretin (TTR) mRNA. Revusiran sodium can be used for transthyretin (TTR)-mediated amyloidosis research.
  • HY-153492A
    Olpasiran sodium
    		Inhibitor 98.82%
    Olpasiran sodium is a small interfering RNA that reduces lipoprotein(a) synthesis in the liver.
  • HY-153493A
    PF-04523655 sodium
    		Inhibitor
    PF-04523655 sodium is a siRNA directed against RTP801 gene. RTP801 sodium is an inhibitor of the mammalian target of rampamycin complex 1 (mTORC1) and downstream transcription factor HIF-1.
  • HY-153482A
    ATU027 sodium
    		Inhibitor 99.22%
    ATU027 sodium is a siRNA, which silences expression of protein kinase N3 (PKN3) in the vascular endothelium. ATU027 sodium has previously been shown to inhibit local tumor invasion as well as lymph node and pulmonary metastasis in mouse cancer models.
  • HY-147266A
    Elebsiran
    		Inhibitor
    Elebsiran is a siRNA against hepatitis B and D virus infections .
  • HY-153483A
    Bamosiran sodium
    		Inhibitor
    Bamosiran sodium is a small interfering RNA targeting β-adrenergic receptor 2, and is used to lower intraocular pressure
  • HY-173593
    Adenosine-3',5'-bisphosphate
    		Inhibitor
    Adenosine-3',5'-bisphosphate is a XRN1 inhibitor (IC50: 36 nM). Adenosine-3',5'-bisphosphate can be used in the study of colorectal cancer, breast cancer and lung cancer.
  • HY-147278A
    Manusiran sodium
    		Inhibitor
    Manusiran (SLN124) sodium, a GalNAc conjugated 19-mer siRNA targeting TMPRSS6 (transmembrane protease serine 6), reduces plasma iron and increases hepcidin levels[1][2].
  • HY-172878
    HDAC/PSMD14-IN-1
    		Inhibitor
    HDAC/PSMD14-IN-1 (Compound 8B) is a thiolutin derivative. HDAC/PSMD14-IN-1 is a orally active dual-target inhibitor of PSMD14/HDAC1 (IC50 238.7 nM/141.2 nM, respectively). HDAC/PSMD14-IN-1 has good cytotoxicity against ESCC cell lines (IC50: 30-250 nM) and effectively reverses epithelial-mesenchymal transition (EMT). HDAC/PSMD14-IN-1 can induce apoptosis. HDAC/PSMD14-IN-1 has anti-tumor activity in a KYSE30 cell mouse xenograft model. HDAC/PSMD14-IN-1 can be used in anti-esophageal cancer research.