2. Signaling Pathways
  3. Others
  4. mRNA

mRNA

messenger RNA

 

mRNA Related Products (319):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-174524
    Human TLR4 mRNA
    Human TLR4 mRNA encodes the human toll like receptor 4 (TLR4) protein, a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR4 has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria.
    Human TLR4 mRNA
  • HY-174783
    Human ACVR2A mRNA
    Human ACVR2A mRNA encodes the human activin A receptor type 2A (ACVR2A) protein, a member of the TGFB family. ACVR2A mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. It may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality.
    Human ACVR2A mRNA
  • HY-174602
    Human IL5 mRNA
    Human IL5 mRNA encodes the human interleukin 5 (IL5) protein, a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL5 plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases.
    Human IL5 mRNA
  • HY-174700
    Human FGF21 mRNA
    Human FGF21 mRNA encodes the human fibroblast growth factor 21 (FGF21) protein, a member of the fibroblast growth factor (FGF) family. FGF21 is a secreted endocrine factor that functions as a major metabolic regulator. It stimulates the uptake of glucose in adipose tissue.
    Human FGF21 mRNA
  • HY-174760
    Human CCL22 mRNA
    Human CCL22 mRNA encodes the human C-C motif chemokine ligand 22 (CCL22) protein, a cytokine that displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. CCL22 also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes.
    Human CCL22 mRNA
  • HY-174544
    Human POU5F1 mRNA
    Human POU class 5 homeobox 1 (POU5F1) mRNA encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis.
    Human POU5F1 mRNA
  • HY-174571
    Human NEUROG2 mRNA
    Human NEUROG2 mRNA encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells. NEUROG2 plays a role in the differentiation and survival of midbrain dopaminergic neurons.
    Human NEUROG2 mRNA
  • HY-174712
    Human FGF1 mRNA
    Human FGF1 mRNA encodes the human Fibroblast growth factor 1 (FGF1) protein, a member of fibroblast growth factor (FGF) family. FGF1 functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It also acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis.
    Human FGF1 mRNA
  • HY-174532
    Human TGFB3 mRNA
    Human TGFB3 mRNA encodes the human transforming growth factor beta 3 (TGFB3) protein, a secreted ligand of the TGF-beta superfamily. TGFB3 is involved in embryogenesis and cell differentiation, and may play a role in wound healing.
    Human TGFB3 mRNA
  • HY-174656
    Human IFNW1 mRNA
    Human IFNW1 mRNA encodes the human interferon omega 1 (IFNW1) protein, an interferon that possesses antiviral activity.
    Human IFNW1 mRNA
  • HY-174610
    Human IL3 mRNA
    Human IL3 mRNA encodes the human interleukin 3 (IL3) protein, a potent growth promoting cytokine. IL3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
    Human IL3 mRNA
  • HY-174685
    Human FLI1 mRNA
    Human FLI1 mRNA encodes a transcription factor containing an ETS DNA-binding domain. FLI1 is a sequence-specific transcriptional activator that can recognize the DNA sequence 5''-C[CA]GGAAGT-3''.
    Human FLI1 mRNA
  • HY-174757
    Human CCL25 mRNA
    Human CCL25 mRNA encodes the human C-C motif chemokine ligand 25 (CCL25) protein, a cytokine that displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils.
    Human CCL25 mRNA
  • HY-174739
    Human CCRL2 mRNA
    Human CCRL2 mRNA encodes the human C-C motif chemokine receptor like 2 (CCRL2) protein, a chemokine receptor like protein. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation.
    Human CCRL2 mRNA
  • HY-174725
    Human CXCR4 mRNA
    Human CXCR4 mRNA encodes the human C-X-C motif chemokine receptor 4 (CXCR4) protein, a CXC chemokine receptor specific for stromal cell-derived factor-1. CXCR4 acts with the CD4 protein to support HIV entry into cells.
    Human CXCR4 mRNA
  • HY-174749
    Human CCL8 mRNA
    Human CCL8 mRNA encodes the human C-C motif chemokine ligand 8 (CCL8) protein, a member of the CC subfamily. CCL8 displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils.
    Human CCL8 mRNA
  • HY-174774
    Human BMPR1B mRNA
    Human BMPR1B mRNA encodes the human bone morphogenetic protein receptor type 1B (BMPR1B) protein, a family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis.
    Human BMPR1B mRNA
  • HY-174691
    Human FGF9 mRNA
    Human FGF9 mRNA encodes the human fibroblast growth factor 9 (FGF9) protein, a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
    Human FGF9 mRNA
  • HY-174718
    Human EPGN mRNA
    Human EPGN mRNA encodes the human epithelial mitogen (EPGN) protein, a member of the epidermal growth factor family. EPGN can promote the growth of epithelial cells and may stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
    Human EPGN mRNA
  • HY-174637
    Human IL13RA2 mRNA
    Human IL13RA2 mRNA encodes the human interleukin 13 receptor subunit alpha 2 (IL13RA2) protein, a subuint of the interleukin 13 receptor complex. IL13RA2 binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.
    Human IL13RA2 mRNA