mRNA Inhibitor

mRNA Inhibitor (1):

Cat. No.	Product Name	Effect	Purity

HY-112905

AN11736	Inhibitor
AN11736 is a CPSF3 inhibitor. AN11736 exerts a potent anti-trypsin effect by specifically inhibiting the activity of the trypanosome CPSF3 endonuclease, disrupting the mRNA maturation process. AN11736 exhibits IC₅₀s against T. congolense and T. vivax of 0.14 and 1.3 nM, respectively. AN11736 exhibits strong anti-trypsin activity in mouse and cattle models.

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