2. Signaling Pathways
  3. Others
  4. mRNA

mRNA

messenger RNA

 

mRNA Related Products (319):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-174519
    Human TLR9 mRNA
    Human TLR9 mRNA encodes the human toll like receptor 9 (TLR9) protein, a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR9 mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
    Human TLR9 mRNA
  • HY-174626
    Human IL1R1 mRNA
    Human IL1R1 mRNA encodes the human interleukin 1 receptor type 1 (IL1R1) protein, a cytokine receptor that belongs to the interleukin-1 receptor family. IL1R1 is an important mediator involved in many cytokine-induced immune and inflammatory responses.
    Human IL1R1 mRNA
  • HY-174613
    Human IL27 mRNA
    Human IL27 mRNA encodes the human interleukin 27 (IL27) protein, one of the subunits of a heterodimeric cytokine complex. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity and induce isotype switching in B-cells.
    Human IL27 mRNA
  • HY-174573
    Human NEUROD1 mRNA
    Human NEUROD1 mRNA encodes the human neuronal differentiation 1 (NEUROD1)protein, a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. NEUROD1 forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box.
    Human NEUROD1 mRNA
  • HY-174535
    Human TGFA mRNA
    Human TGFA mRNA encodes the human transforming growth factor alpha (TGFA) protein. TGFA is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development.
    Human TGFA mRNA
  • HY-174714
    Human FAS mRNA
    Human FAS mRNA encodes the human Fas cell surface death receptor (FAS) protein, a member of the TNF-receptor superfamily. FAS has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system.
    Human FAS mRNA
  • HY-174608
    Human IL32 mRNA
    Human IL32 mRNA encodes the human interleukin 32 (IL32) protein, a member of the cytokine family. IL32 induces the production of TNFalpha from macrophage cells.
    Human IL32 mRNA
  • HY-174675
    Human GATA3 mRNA
    Human GATA3 mRNA encodes the human GATA binding protein 3 (GATA3) which belongs to the GATA family. GATA3 is an important regulator of T-cell development. It also plays an important role in endothelial cell biology.
    Human GATA3 mRNA
  • HY-174549
    Human PDGFRA mRNA
    Human PDGFRA mRNA encodes the human platelet derived growth factor receptor alpha (PDGFRA) protein, a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. PDGFRA may play a role in organ development, wound healing, and tumor progression.
    Human PDGFRA mRNA
  • HY-174780
    Human AMHR2 mRNA
    Human AMHR2 mRNA encodes the human anti-Mullerian hormone receptor type 2 (AMHR2) protein, a receptor for the anti-Mullerian hormone (AMH).
    Human AMHR2 mRNA
  • HY-174566
    Human NRG2 mRNA
    Human NRG2 mRNA encodes the human neuregulin 2 (NRG2) protein, a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, NRG2 can induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.
    Human NRG2 mRNA
  • HY-174716
    Human EREG mRNA
    Human EREG mRNA encodes the human epiregulin (EREG) protein, a member of the epidermal growth factor family. EREG may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation.
    Human EREG mRNA
  • HY-174572
    Human NEUROD2 mRNA
    Human NEUROD2 mRNA encodes the human neuronal differentiation 2 (NEUROD2) protein, a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Human NEUROD2 can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.
    Human NEUROD2 mRNA
  • HY-174499
    Cas9 Nickase mRNA (5moU)
    Cas9 Nickase mRNA expresses a version of the Streptococcus pyogenes SF370 Cas9 protein (CRISPR Associated Protein 9) that contains a D10A amino acid substitution. This mRNA also contains a C-terminal nuclear localization signal followed by a HA tag.Cas9 functions as part of the CRISPR (clustered regularly interspaced short palindromic repeats) genome editing system. In the CRISPR system, an RNA guide sequence targets the site of interest and the Cas9 protein is employed to perform the DNA cleavage. While wild-type Cas9 creates a double-stranded break at the target site, Cas9 nickase creates a single-stranded break. This favors homology-directed repair and decreases the occurrence of non-homologous end joining.
    Cas9 Nickase mRNA (5moU)
  • HY-174745
    Human CCR3 mRNA
    Human CCR3 mRNA encodes the human C-C motif chemokine receptor 3 (CCR3) protein, a member of G protein-coupled receptors family. CCR3 may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.
    Human CCR3 mRNA
  • HY-174525
    Human TLR3 mRNA
    Human TLR3 mRNA encodes the human toll like receptor 3 (TLR3) protein, a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR3 recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses.
    Human TLR3 mRNA
  • HY-174577
    Human MYC mRNA
    Human MYC mRNA encodes the human MYC proto-oncogene, bHLH transcription factor (MYC) protein, a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation.
    Human MYC mRNA
  • HY-174583
    Human MEF2C mRNA
    Human MEF2C mRNA encodes the human myocyte enhancer factor 2C (MEF2C) protein, a member of the MADS box transcription enhancer factor 2 (MEF2) family. MEF2C has both trans-activating and DNA binding activities and may play a role in maintaining the differentiated state of muscle cells.
    Human MEF2C mRNA
  • HY-174644
    Human IL11 mRNA
    Human IL11 mRNA encodes the human interleukin 11 (IL11) protein, a member of the gp130 family of cytokines. IL11 is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells.
    Human IL11 mRNA
  • HY-174699
    Human FGF22 mRNA
    Human FGF22 mRNA encodes the human fibroblast growth factor 22 (FGF22) protein, a member of the fibroblast growth factor (FGF) family. FGF22 plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. It also can stimulate cell proliferation (in vitro) and may be involved in hair development.
    Human FGF22 mRNA