2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1385):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-34887
    Acridone-4-carboxylic acid
    		98.69%
    Acridone-4-carboxylic acid (ACA) (Compound 2c) is a heme-interacting acridone derivatives that prevents free heme-mediated protein oxidation and degradation. Acridone-4-carboxylic acid inhibits protein carbonyl formation with an IC50 of 43 μM.
    Acridone-4-carboxylic acid
  • HY-128856
    P7C3-OMe
    		98.26%
    P7C3-OMe is a pro-neurogenic compound, has therapeutic benefits in neuropsychiatric and/or neurodegenerative disease. The R-enantiomer of P7C3-OMe is far more active than the S-enantiomer.
    P7C3-OMe
  • HY-76779
    4-(Chloromethyl)-7-hydroxycoumarin
    		98.01%
    4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII.
    4-(Chloromethyl)-7-hydroxycoumarin
  • HY-12692
    DO3A tert-Butyl ester
    		≥98.0%
    DOTA tert-Butyl ester is a cyclic tosamide benzyl derivative.
    DO3A tert-Butyl ester
  • HY-139453
    LP-184
    		99.37%
    LP-184 (compound 6), an acylfulvene analog, inhibits tumor growth. LP-184 has potent anti-cancer activity in the ovarian, colon, prostate and pancreatic cell lines. (patent WO2007019308A2).
    LP-184
  • HY-105270A
    Tallimustine hydrochloride
    		98.23%
    Tallimustine hydrochloride, a distamycin-A derivative, is an anticancer agent.
    Tallimustine hydrochloride
  • HY-W072385
    1,2-Dibromo-4,5-methylenedioxybenzene
    		99.82%
    1,2-Dibromo-4,5-methylenedioxybenzene is an impurity in the synthesis of amphetamines.
    1,2-Dibromo-4,5-methylenedioxybenzene
  • HY-176462
    Gly-Dasatinib
    Gly-Dasatinib (compound I-7-1), an amino acid analog of Dasatinib (HY-10181), is a tyrosine kinase inhibitor. Gly-Dasatinib can be used for the study of cancer.
    Gly-Dasatinib
  • HY-159162A
    7-(2-Aminoethyl)camptothecin TFA
    		99.61%
    7-(2-Aminoethyl)camptothecin TFA (7CPT TFA) is the TFA salt form of Camptothecin (HY-16560) derivative 7-(2-Aminoethyl)camptothecin (HY-159162). 7-(2-Aminoethyl)camptothecin TFA can be used for synthesis of conjugate with triple helix-forming oligonucleotides (TFOs) and camptothecin (CPT). The TFO-CPT conjugate is used for DNA cleavage.
    7-(2-Aminoethyl)camptothecin TFA
  • HY-76633
    Dimethyl 4-hydroxyisophthalate
    		99.66%
    Dimethyl 4-hydroxyisophthalate is a methyl salicylate analogue.
    Dimethyl 4-hydroxyisophthalate
  • HY-B1185
    Beclamide
    		98.86%
    Beclamide is an active molecule with anticonvulsant activity, used as an anticonvulsant drug.
    Beclamide
  • HY-130702
    24(28)-Dehydroergosterol
    24(28)-Dehydroergosterol is a derivative of Episterol. Episterol is a sterol involved in the biosynthesis of steroids.
    24(28)-Dehydroergosterol
  • HY-B2191
    Sodium gualenate
    		≥98.0%
    Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.
    Sodium gualenate
  • HY-P2023
    Hirugen
    Hirugen is a derivative of hirudin, an anticoagulant protein found in leeches.
    Hirugen
  • HY-U00148
    KY-556
    		98.59%
    KY-556 is a promising and orally-active pro-agent of disodium cromoglycate (DSCG) against allergic diseases.
    KY-556
  • HY-B1045A
    Chlorazanil
    Chlorazanil is a triazine derivative and also a new nonmercurial diuretic agent.
    Chlorazanil
  • HY-111178
    Lauflumide
    		99.89%
    Lauflumide (BisfluoroModafinil) is the common alternative of modafinil. Modafinil is commonly prescribed for the research narcolepsy. Lauflumide has the potential for cognitive enhancing.
    Lauflumide
  • HY-W029411
    4-(Benzo[d]oxazol-2-yl)aniline
    		99.93%
    4-(Benzo[d]oxazol-2-yl)aniline is a potent antitumor agent. 4-(Benzo[d]oxazol-2-yl)aniline has inhibitory activity against mammary carcinoma cell lines.
    4-(Benzo[d]oxazol-2-yl)aniline
  • HY-106538
    Cadralazine
    		98.74%
    Cadralazine (ISF 2469) is an orally active antihypertensive agent. Cadralazine is a peripheral arteriolar vasodilator.
    Cadralazine
  • HY-145104
    Antioxidant agent-1
    		98.23%
    Antioxidant agent-1 is a new chalcone derivative as a potential antioxidant agent.
    Antioxidant agent-1