2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1652):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-164165
    Paclitaxel-2′-succinate NHS ester
    		98.78%
    Paclitaxel-2′-succinate NHS ester is a paclitaxel derivative with a succinic acid linker, in which the carboxyl group is activated by the NHS ester. The NHS ester group is highly reactive toward amino or hydroxyl groups and can be used to conjugate with other molecules such as peptides, proteins, antibodies, enzymes or polymers. Paclitaxel-2′-succinate NHS ester can be used in the development of nanomedicines and in the study of cancer therapy.
    Paclitaxel-2′-succinate NHS ester
  • HY-N3126
    Orsellinic acid
    		98.36%
    Orsellinic acid is a Benzoic acid (HY-N0216) derivative. Orsellinic acid can be isolated from Chaetomium globosum endophytic on Ephedra fasciculata (Mormon tea). Orsellinic acid blocks PAF-mediated Apoptosis, inhibits caspase-3/7 activation, and PARP cleavage. Orsellinic acid can be used in research of neurons and various tumors (non-small cell lung cancer, breast cancer, neuroblastoma, pancreatic cancer).
    Orsellinic acid
  • HY-137905
    Pomalidomide-amido-C5-PEG2-C6-chlorine
    		99.69%
    Pomalidomide-amido-C5-PEG2-C6-chlorine is a derivant of Pomalidomide (HY-10984).
    Pomalidomide-amido-C5-PEG2-C6-chlorine
  • HY-W002450
    L-Cyclohexylalanine
    		≥98.0%
    L-Cyclohexylalanine is an amino acid derivative. L-Cyclohexylalanine modifies an atrial natriuretic peptide, regulates homeostasis of body fluid and blood pressure homeostasis and vasodilation activity.
    L-Cyclohexylalanine
  • HY-145967A
    (R)-FT709
    (R)-FT709 is an active compound. (R)-FT709 can be used for the research of cancers.
    (R)-FT709
  • HY-133597
    4-Chlorocatechol
    		99.37%
    4-Chlorocatechol is a major degradation product of 4-chloro-2-aminophenol (4C2AP). 4-Chlorocatechol is also a substrate for catechol 1,2-dioxygenases and chlorocatechol dioxygenase.
    4-Chlorocatechol
  • HY-W039116
    Thalidomide-4-Br
    		99.70%
    Thalidomide-4-Br (compound 53) is a compound with a bromodomain. Thalidomide-4-Br can be used in the research of inflammation, tumor and neurology.
    Thalidomide-4-Br
  • HY-W003903A
    Methyl benzyl-L-serinate
    		98.19%
    Methyl benzyl-L-serinate is a serine derivative.
    Methyl benzyl-L-serinate
  • HY-W011180
    Vitamin A Propionate
    Vitamin A Propionate is an ester compound of vitamin A. In nutritional studies of foals, different doses have different effects on growth, serum biochemistry and hematological indicators. Too high or too low doses will produce adverse effects and are related to the vitamin A concentration in plasma, liver and kidneys.
    Vitamin A Propionate
  • HY-U00153
    Dixyrazine
    		99.87%
    Dixyrazine, a phenothiazine derivative, can prevent brain oedema induced by intracarotid injection of protamine sulphate.
    Dixyrazine
  • HY-34763
    7-Hydroxycarbostyril
    		99.05%
    7-Hydroxycarbostyril (7-Hydroxy-2(1H)-quinolinone) (Compound 7) is a quinolinone derivative. 7-Hydroxycarbostyril can be used for synthesis of Brexpiprazole (HY-15780). Brexpiprazole, a typical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor.
    7-Hydroxycarbostyril
  • HY-W050088
    Isoxepac
    		99.92%
    Isoxepac (HP 549) is an orally active non-steroidal anti-inflammatory agent. Isoxepac can inhibit Carrageenan (HY-125474) paw oedema, adjuvant-induced polyarthritis, and prostaglandin synthesis. Isoxepac (200 mg) has an analgesic effect after meniscectomy with a low incidence of side effects. Isoxepac can be used in the research of inflammatory (rheumatoid arthritis) and pain-related diseases.
    Isoxepac
  • HY-N10478A
    Sitosterol sulfate (trimethylamine)
    Sitosterol sulfate (trimethylamine) is an active compound. Sitosterol sulfate can be used in a variety of biological research.
    Sitosterol sulfate (trimethylamine)
  • HY-105270A
    Tallimustine hydrochloride
    		98.23%
    Tallimustine hydrochloride, a distamycin-A derivative, is an anticancer agent.
    Tallimustine hydrochloride
  • HY-131142
    Monensin methyl ester
    		99.18%
    Monensin methyl ester, a neutral analog of Monensin (HY-N4302), is an ion active component for Na+ selective disk electrodes.
    Monensin methyl ester
  • HY-22183
    Anticonvulsant agent 3
    		99.64%
    Anticonvulsant agent 3 is a 2-amino derivative with anticonvulsant activity[1].
    Anticonvulsant agent 3
  • HY-76633
    Dimethyl 4-hydroxyisophthalate
    		99.66%
    Dimethyl 4-hydroxyisophthalate is a methyl salicylate analogue.
    Dimethyl 4-hydroxyisophthalate
  • HY-B1185
    Beclamide
    		98.86%
    Beclamide is an active molecule with anticonvulsant activity, used as an anticonvulsant drug.
    Beclamide
  • HY-124031
    Lobetyolinin
    		98.98%
    Lobetyolinin is a polyacetylene compound. Lobetyolinin can be extracted from the traditional Chinese medicine Codonopsis pilosula. Lobetyolinin has antiarrhythmic effects. Lobetyolinin can be used in liver cancer research.
    Lobetyolinin
  • HY-Z16070
    Hydronopol
    		98.09%
    Hydronopol is a saturated alcohol terpene derivative. Hydronopol shows central inhibitory, anticonvulsant, analgesic, anticholinergic and antihypertensive activities. Hydronopol can be used for the researches of neurological and cardiovascular disease.
    Hydronopol