2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1652):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-128695
    Oleanolic acid hemiphthalate disodium salt
    		98.05%
    Oleanolic acid hemiphthalate disodium salt is a hemiphthalate derivative of Oleanolic acid (HY-128695) with anti-inflammatory and potential anti-ulcer activities.
    Oleanolic acid hemiphthalate disodium salt
  • HY-118300
    Abitesartan
    Abitesartan is an active compound.
    Abitesartan
  • HY-116518
    Piperafizine A
    Piperafizine A (compound 4d’) is a N-monoalkylated plinabulin derivative. Anti-cancer reagent.
    Piperafizine A
  • HY-124929
    Mimocin
    Mimocin is an active compound.
    Mimocin
  • HY-49065
    WAY-658494
    WAY-658494 is an active molecule.
    WAY-658494
  • HY-B0910AR
    Pyrithioxin dihydrochloride (Standard)
    Pyrithioxin (Pyritinol) dihydrochloride (Standard) is the analytical standard of Pyrithioxin dihydrochloride (HY-B0910A). Pyrithioxin (Pyritinol) is an orally active neurodynamic compound. Pyrithioxin can promote the metabolism of glucose and amino acids, increase carotid blood flow and improve cerebral blood flow. Pyrithioxin exhibits anti-inflammation, anti-tumor and neuroprotective effect. Pyrithioxin can be used for the researches of cancer, inflammation, immunology, metabolic and neurological disease such as cerebral infarct, epilepsy, fibrosarcomas and rheumatoid polyarthritis.
    Pyrithioxin dihydrochloride (Standard)
  • HY-N16644
    4'-O-Methylthujaplicatin
    4'-O-Methylthujaplicatin is a thujaplicatin derivative. 4'-O-Methylthujaplicatin is related to the Yatein (HY-N1060) biosynthetic pathway.
    4'-O-Methylthujaplicatin
  • HY-106502
    4′-Deoxydoxorubicin
    4′-Deoxydoxorubicin (Esorubicin) is the derivative of Doxorubicin (HY-15142A). 4′-Deoxydoxorubicin can be used for the research of cancer.
    4′-Deoxydoxorubicin
  • HY-168736
    CRC-IN-1
    CRC-IN-1 (compound (-)-15h) is a potent anti-colorectal cancer (CRC) agent, as well as a derivative of the anticancer agent Evodiamine (HY-N0114).
    CRC-IN-1
  • HY-N16646
    Micrometam A
    Micrometam A is a phenethylamine derivative found in Micromelum falcatum. Micrometam A exhibits anti-halogenation activity with a LD50 of 18.5 μg/mL.
    Micrometam A
  • HY-W585893R
    Endrin ketone (Standard)
    Endrin ketone (Standard) is the analytical standard of Endrin ketone. This product is intended for research and analytical applications. Endrin ketone is an Endrin degradation product. Endrin is a carcinogen.
    Endrin ketone (Standard)
  • HY-175846
    TQFL13
    TQFL13 is derivative of Thymoquinone (TQ) (HY-D0803) with potent anti-breast cancer activity. TQFL13 exhibits higher cytotoxicity against breast cancer cells (BT549, MDA-MB-231, 4T1). TQFL13 increases apoptosis and blocks the cell cycle at S and G2/G1 phases in breast cancer cells. TQFL13 shows dose-dependent anti-tumor efficacy in mouse breast cancer allograft model. TQFL13 can be used for the study of breast cancer.
    TQFL13
  • HY-129313
    LG 6-102
    LG 6-102 is an active compound.
    LG 6-102
  • HY-134280
    8-Br-NHD+
    8-Br-NHD+ (Nicotinamide 8-Br-hypoxanthine dinucleotide) is a derivative of NAD+ (nicotinamide adenine dinucleotide) that acts as a potential substrate, competitive inhibitor or modulator of enzymes that interact with β-NAD+. 8-Br-NHD+ can be used to synthesize a cyclic ADP nucleotide (cADPR) analog.
    8-Br-NHD+
  • HY-P10885
    Lead-lapemelanotide zapixetan
    Lead-lapemelanotide zapixetan is a precursor of lapemelanotide, which can be used in life science research.
    Lead-lapemelanotide zapixetan
  • HY-105060
    TA 077
    TA 077 is a nitrosourea derivative with antitumor activity. TA 077 can be used for the research of cancer, such as lung cancer and leukemia.
    TA 077
  • HY-13631T
    (1R,9S)-Exatecan
    (1R,9S)-Exatecan (DX8951f) is the (1R,9S) stereoisomer of Exatecan (HY-13631). Exatecan (DX-8951) is a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
    (1R,9S)-Exatecan
  • HY-173584
    GSK484-Ph
    GSK484-Ph (compound 15d) is an analog of GSK484 (HY-100514) with potent anticancer effects. GSK484-Ph potently inhibits 4T1 cells and can be used for the study of breast cancer.
    GSK484-Ph
  • HY-W740221
    7-Ethylcamptothecin-d3-1
    7-Ethylcamptothecin-d3-1 is the deuterium labeled 7-Ethylcamptothecin (HY-N2108). 7-Ethylcamptothecin is a derivative of Camptothecin (HY-16560) and a key intermediate in the synthesis of SN-38 (HY-13704). 7-Ethylcamptothecin can be used in tumor-related research.
    7-Ethylcamptothecin-d<sub>3</sub>-1
  • HY-N16131
    Sydonic acid
    Sydonic acid is a bisabolane-type sesquiterpenoid that can be isolated from the fungus Aspergillus sydowii BTBU20213012, which was obtained from a marine sediment sample in the Western Pacific.
    Sydonic acid