2. Signaling Pathways
  3. Others
  4. Others

Others

 
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-102081
    2OH-BNPP1
    		99.65%
    2OH-BNPP1 is an inhibitor of BUB1 kinase, a Ser/Thr kinase, used for the treatment of cancer.
    2OH-BNPP1
  • HY-118090
    L-γ-Glutamyl-L-glutamic acid
    		99.72%
    L-γ-Glutamyl-L-glutamic acid (γ-Glu-Glu) is the isomer of D-γ-Glutamyl-D-glutamic acid (HY-118090A), and can be used as an experimental control. D-γ-Glutamyl-D-glutamic acid is a poly(γ-glutamic acid) of clusters of D- and D-glutamic acid repeating units in a linear chain.
    L-γ-Glutamyl-L-glutamic acid
  • HY-136990
    GLPG0259
    		99.84%
    GLPG0259 is a ATP-competitive inhibitor of MAPK-activated protein kinase 5 (MK5) with oral activity. GLPG0259 reduces inflammation and bone destruction in a mouse model of collagen-induced arthritis. GLPG0259 also inhibited the metastasis of prostate cancer (PCa) cells.
    GLPG0259
  • HY-106844A
    (+)-EMD 57033
    		99.72%
    (+)-EMD 57033 is a cardiac troponin C (cTnC) activator, is a dominant Ca2+ sensitizer. (+)-EMD 57033 binds the cardiac/slow skeletal troponin C isoform and exerts myocardial contractile promotion function.
    (+)-EMD 57033
  • HY-W614925
    4-Hydroxyphenylacetaldehyde
    		98.96%
    4-Hydroxyphenylacetaldehyde is an intermediate in dopamine metabolism. 4-Hydroxyphenylacetaldehyde can be used in neurological and cancer related research.
    4-Hydroxyphenylacetaldehyde
  • HY-107343
    Docosahexaenoic acid ethyl ester
    Docosahexaenoic acid ethyl ester (Ethyl docosahexaenoate) is a 90% concentrated ethyl ester of docosahexaenoic acid manufactured from the microalgal oil. Docosahexaenoic acid ethyl ester enhances 6-hydroxydopamine-induced neuronal damage by induction of lipid peroxidation in mouse striatum. Docosahexaenoic acid (DHA) is a key component of the cell membrane, and its peroxidation is inducible due to the double-bond chemical structure. Docosahexaenoic acid has neuroprotective effects.
    Docosahexaenoic acid ethyl ester
  • HY-W068212
    16-Hydroxyhexadecanoic acid
    		98.0%
    16-Hydroxyhexadecanoic acid (Juniperic acid) is one of the main monomers of cutin in Vicia faba flower petals. 16-Hydroxyhexadecanoic acid can be used as an internal standard for the measurement of hydroxy and hydroperoxy fatty acids in plasma.
    16-Hydroxyhexadecanoic acid
  • HY-145551
    Atinvicitinib
    		98.03%
    Atinvicitinib is a kind of pyrazole compound. Atinvicitinib has the potential for the research of atopic dermatitis (extracted from patent WO2021123094A1).
    Atinvicitinib
  • HY-146695
    S100P-IN-1
    		Inhibitor 99.74%
    S100P-IN-1 (Compound 4) is a S100P inhibitor with an IC50 of 22.7 nM. S100P-IN-1 shows anti-metastatic effects on pancreatic cancer cells.
    S100P-IN-1
  • HY-W012145
    TMPD dihydrochloride
    		98.81%
    TMPD dihydrochloride, a readily oxidizable compound, is an enzymatically convert redox active substrate molecule. TMPD dihydrochloride is also an electron donor and serves as a reducing cosubstrate for heme peroxidases. TMPD dihydrochloride is also a complex IV substrate.
    TMPD dihydrochloride
  • HY-163084
    HJ445A
    		98.31%
    HJ445A is a potent MYOF inhibitor and binds to the MYOF-C2D domain with a KD of 0.17 μM. HJ445A potently repressed the proliferation of gastric cancer cells with IC50 values of 0.16 and 0.14 μM in MGC803 and MKN45, respectively. HJ445A demonstrates superior antitumor efficacy in vivo and can be used for cancer research.
    HJ445A
  • HY-111652
    S-Gboxin
    		Inhibitor 99.62%
    S-Gboxin is a functional analog of the oxidative phosphorylation (OXPHOS) inhibitor Gboxin and has antitumor activity. S-Gboxin inhibits the growth of mouse and human glioblastoma with an IC50 of 470 nM. S-Gboxin has antitumor activity.
    S-Gboxin
  • HY-112440
    HZX-02-059
    		Activator 99.40%
    HZX-02-059 is a potent methuosis inducer and dual-target PIKfyve/tubulin inhibitor with anticancer activity. Methuosis mainly disrupts the balance of endocytosis and exocytosis, forming a large number of vesicles and inducing cell death. HZX-02-059 also induces cell vacuolization, promotes apoptosis, downregulates the p53 pathway, inhibits PI3K/AKT phosphorylation, and inhibits c-Myc and NF-κB transcription.
    HZX-02-059
  • HY-107661
    Arundic Acid
    		Modulator 98.0%
    Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid also increases the expression level of EAAT1 by activating the Akt, ERK, and NF-κB signaling pathways, which has the potential to eliminate excess glutamate and inhibit excitotoxic brain damage or death. Arundic acid has the potential for stroke and Alzheimer’s disease research.
    Arundic Acid
  • HY-48999A
    FSK hydrochloride
    		99.24%
    FSK hydrochloride is fluorosulfonyloxybenzoyl-l-lysine, with a long and flexible aryl fluorosulfate-containing side chain that can reach protein sites that are difficult to reach by covalent linkage. FSK hydrochloride is a modified nanomolecule that targets the epidermal growth factor receptor (EGFR), creating a covalent binding that results in irreversible binding. FSK hydrochloride captures unknown enzyme-substrate interactions in living cells through genetically encoded chemical cross-linking, targeting residues beyond Cys, and cross-linking at the binding periphery. FSK hydrochloride enables the construction of bioreactive SuFEx systems for creating covalent bonds in different proteins in vitro and in vivo.
    FSK hydrochloride
  • HY-147319
    RTI-7470-44
    		99.85%
    RTI-7470-44 is a potent, selective and blood-brain barrier (BBB) penetrant human trace amine-associated receptor subtype 1 (hTAAR1) antagonist with an IC50 value of 8.4 nM and a Ki value of 0.3 nM. RTI-7470-44 has moderate metabolic stability, and a favorable preliminary off-target profile. RTI-7470-44 can increase the spontaneous firing rate of mouse ventral tegmental area (VTA) dopaminergic neurons. RTI-7470-44 can be used for researching schizophrenia, agent addiction, and Parkinson’s disease (PD).
    RTI-7470-44
  • HY-P10632
    HiBiT tag
    		98.11%
    HiBiT tag is a complimentary peptide (VSGWRLFKKIS), with high affinity for LgBiT. HiBiT tag is fused to the Gβ subunit of the receptor. The complementation of LgBiT and HiBiT facilitates the stabilization of ETR and G protein. HiBiT is attached to a protein of interest (GFP) to quantify transport to the cytosol.
    HiBiT tag
  • HY-B1469
    Isosorbide
    		98.76%
    Isosorbide (D-Isosorbide), an orally active vasodilating agent that can be used for the research of heart failure and angina (chest pain). Isosorbide is also an oral hyperosmotic diuretic.
    Isosorbide
  • HY-112431A
    Carnostatine hydrochloride
    		Inhibitor 99.00%
    Carnostatine hydrochloride (SAN9812 hydrochloride) is a potent and selective carnosinase 1 (CN1) inhibitor with a Ki of 11 nM for human recombinant CN1. Carnostatine hydrochloride can be used for the treatment of diabetic nephropathy (DN).
    Carnostatine hydrochloride
  • HY-N1406
    6-Methylcoumarin
    		99.98%
    6-Methylcoumarin is a synthetic fragrance widely used in cosmetics.
    6-Methylcoumarin
Cat. No. Product Name / Synonyms Application Reactivity