Others Inhibitor

Others Inhibitors (103):

Cat. No.	Product Name	Effect	Purity

HY-112134

CSN5i-3	Inhibitor	99.95%
CSN5i-3 is a potent, selective and orally available inhibitor of CSN5/Jab1, and inhibits CSN-catalysed Cul1 deneddylation with an IC₅₀ value of 5.8 nM.

HY-18630A

Ro 48-8071 fumarate	Inhibitor	99.13%
Ro 48-8071 fumarate is an inhibitor of OSC (Oxidosqualene cyclase) with IC₅₀ of appr 6.5 nM.

HY-18681

Voxelotor	Inhibitor	99.99%
Voxelotor (GBT 440) is a potent inhibitor of haemoglobin S (HbS) polymerization. Voxelotor has the potential for sickle cell disease (SCD) treatment.

HY-13746B

Sardomozide dihydrochloride	Inhibitor	99.73%
Sardomozide dihydrochloride is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC₅₀ of 5 nM.

HY-101464

ML329	Inhibitor	≥98.0%
ML329 is a micropthalmia-associated transcription factor (MITF) inhibitor, which inhibits TRPM-1 promoter activity with an IC₅₀ of 1.2 μM.

HY-109081

Cedazuridine	Inhibitor	≥98.0%
Cedazuridine (E7727) (Compound 7a) is an orally active cytidine deaminase (CDA) inhibitor with an IC₅₀ value of 0.4 μM. Cedazuridine can be used for cancer research.

HY-101144

RSM-932A	Inhibitor	98.44%
RSM-932A (TCD-717) is a specific ChoKα inhibitor with IC₅₀s of 1 and 33 μM for human recombinant ChoKα and ChoKβ enzymes, respectively. RSM-932A acts as the “first in humans” compound targeting ChoKα. RSM-932A is potent in vitro anti-proliferative and in vivo anti-tumoral activity against human xenografts in mice, showing high efficacy with low toxicity profiles.

HY-115510

SPR inhibitor 3	Inhibitor	99.84%
SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell-free assay (IC₅₀=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC₅₀=5.2 μM). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels.

HY-112902

OGG1-IN-08	Inhibitor	99.60%
OGG1-IN-08 is a potent 8-oxoguanine DNA glycosylase-1 (OGG1) inhibitor with an IC₅₀ value of 0.22 μM. OGG1-IN-08 decreases both the glycosylase and lyase activities of OGG1.

HY-111365

TES-1025	Inhibitor	98.12%
TES-1025 is a potent and selective human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) inhibitor with an IC₅₀ of 13 nM.

HY-102074

ERDRP-0519	Inhibitor	99.90%
ERDRP-0519, an orally bioavailable small-molecule Measles virus (MeV) polymerase inhibitor, prevents measles disease in squirrel monkeys (Saimiri sciureus). ERDRP-0519 inhibits morbilliviruses with nanomolar potency..

HY-158009

SGF29-IN-1	Inhibitor	≥98.0%
SGF29-IN-1 (Compound Cpd_DC60) is a selective inhibitor for Spt-Ada-Gcn5 acetyltransferase (SAGA)–associated factor 29 (SGF29)-Tudor domain. SGF29-IN-1 exhibits activity against leukemia.

HY-146695

S100P-IN-1	Inhibitor	99.74%
S100P-IN-1 (Compound 4) is a S100P inhibitor with an IC₅₀ of 22.7 nM. S100P-IN-1 shows anti-metastatic effects on pancreatic cancer cells.

HY-112619

TES-991	Inhibitor	99.65%
TES-991 is a potent and selective human α Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) inhibitor, with an IC₅₀ of 3 nM.

HY-14454

TPh A	Inhibitor	99.81%
TPh A (Triphenyl Compound A) is a potent inhibitor of the nuclear protein pirin and binds specifically to pirin with a K_i of 0.6 uM. TPh A disrupts the formation of the bcl3–pirin complex. TPh A can be used as a novel small molecule tool to regulate pirin in cells.

HY-120252

ABC44	Inhibitor	98.7%
ABC44 is a potent serine hydrolase inhibitor with IC₅₀s of 0.1 μM and 6.5 μM for palmitoyl protein thioesterase 1 (PPT1) in situ and in vitro, respectively. ABC44 can be used for researching infantile neuronal ceroid lipofuscinosis.

HY-139616

Sec61-IN-2	Inhibitor	99.51%
Sec61-IN-2 (A347) is a protein secretion inhibitor (extracted from patent WO2020176863).

HY-112097

E260	Inhibitor	99.05%
E260 is a Fer/FerT kinase inhibitor.

HY-111652

S-Gboxin	Inhibitor	99.62%
S-Gboxin is a functional analog of the oxidative phosphorylation (OXPHOS) inhibitor Gboxin and has antitumor activity. S-Gboxin inhibits the growth of mouse and human glioblastoma with an IC₅₀ of 470 nM. S-Gboxin has antitumor activity.

HY-112431A

Carnostatine hydrochloride	Inhibitor	99.81%
Carnostatine hydrochloride (SAN9812 hydrochloride) is a potent and selective carnosinase 1 (CN1) inhibitor with a K_i of 11 nM for human recombinant CN1. Carnostatine hydrochloride can be used for the treatment of diabetic nephropathy (DN).

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