2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-14608S3
    L-Glutamic acid-13C5,15N
    		99.9%
    L-Glutamic acid-13C5,15N is the 13C- and 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
    L-Glutamic acid-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N
  • HY-P2804
    GAPDH, rabbit muscle
    Glyceraldehyde phosphate dehydrogenase (EC 1.2.1.12) is the target of anti-thymocyte and anti-apoptotic agents. Glyceraldehyde phosphate dehydrogenase catalyzes the chain oxidation of reduced nicotinamide adenine dinucleotide by perhydroxyl radicals.
    GAPDH, rabbit muscle
  • HY-W017007
    3-Methyl-L-histidine
    		99.98%
    3-Methyl-L-histidine is an endogenous amino acid that can be found in actin and myosin.
    3-Methyl-L-histidine
  • HY-100587
    D-Glutamine
    		98.0%
    D-Glutamine is a cell-permeable D type stereoisomer of Glutamine.
    D-Glutamine
  • HY-128852
    N-Acetyl-D-galactosamine, 98%
    		99.85%
    N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets. N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin.
    N-Acetyl-D-galactosamine, 98%
  • HY-W018555
    D-Cysteine
    		≥98.0%
    D-Cysteine, the D-isomer of cysteine, is an orally active antibacterial agent and a regulator of neural progenitor cell proliferation. D-Cysteine can inhibit Escherichia coli, Streptococcus mutans, and Streptococcus sanguinis. The no-observed-adverse-effect level of D-Cysteine in rats should be less than 500 mg/kg/day.
    D-Cysteine
  • HY-P2806
    Pyruvate Kinase, Microorganism
    Pyruvate Kinase, Microorganism (PK) is a glycolytic enzyme that catalyzes the conversion of phosphoenolpyruvate and ADP to pyruvate and ATP.
    Pyruvate Kinase, Microorganism
  • HY-113371
    2-Methylcitric acid
    		99.72%
    2-Methylcitric acid (Methylcitric acid) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate.
    2-Methylcitric acid
  • HY-101407
    Nicotinamide N-oxide
    		99.85%
    Nicotinamide N-oxide, an in vivo nicotinamide metabolite, is a potent, and selective antagonist of the CXCR2 receptor.
    Nicotinamide N-oxide
  • HY-N2144
    7,4'-Di-O-methylapigenin
    		99.01%
    The compound 7,4'-Di-O-methylapigenin may be partly responsible for the reported antifungal activity of C.
    7,4'-Di-O-methylapigenin
  • HY-W012531
    2-Hydroxycinnamic acid
    		99.86%
    2-Hydroxycinnamic acid is a phenolic acid with antimicrobial and antioxidant properties. 2-Hydroxycinnamic acid has antimicrobial activity against Staphylococcus aureus and is not susceptible to drug resistance. 2-Hydroxycinnamic acid shows inhibitory effects on infection of HIV/SARS-CoV S pseudovirus with an IC50 of 0.3 mM. In addition, 2-Hydroxycinnamic acid has neuroprotective and antitumor activity.
    2-Hydroxycinnamic acid
  • HY-B0225
    Methyldopa
    		98.25%
    Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system.
    Methyldopa
  • HY-B0502A
    Enrofloxacin monohydrochloride
    		99.73%
    Enrofloxacin monohydrochloride (BAY Vp 2674 monohydrochloride) is an effective antibiotic with an MIC90 of 0.312 μg/mL for Mycoplasma bovis. Enrofloxacin monohydrochloride shows inhibitory activity against vaccinia virus (VV).
    Enrofloxacin monohydrochloride
  • HY-107846
    Xylan
    Xylan represents the main hemicellulose component in the secondary plant cell walls of flowering plants. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose.
    Xylan
  • HY-B2209A
    Hydroxocobalamin monohydrochloride
    		99.93%
    Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia.
    Hydroxocobalamin monohydrochloride
  • HY-107512
    Kynurenic acid sodium
    		99.82%
    Kynurenic acid sodium, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid sodium is also an agonist of GPR35/CXCR8.
    Kynurenic acid sodium
  • HY-126854
    N-Acetyllactosamine
    		99.95%
    N-Acetyllactosamine (N-Acetyl-D-lactosamine), a nitrogen-containing disaccharide, is a galectin-3 inhibitor, which is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects.
    N-Acetyllactosamine
  • HY-N1428S
    Citric acid-d4
    		99.31%
    Citric acid-d4 is the deuterium labeled Citric acid (HY-N1428). Citric acid is a natural preservative and food tartness enhancer. Citric acid induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries.
    Citric acid-d<sub>4</sub>
  • HY-W017018S4
    L-Ornithine-d7 hydrochloride
    		99.90%
    L-Ornithine-d7 (hydrochloride) is the deuterium labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.
    L-Ornithine-d<sub>7</sub> hydrochloride
  • HY-113415A
    Testosterone sulfate (pyridinium)
    		99.89%
    Testosterone sulfate pyridinium is a Testosterone sulfate with a pyridinium. Testosterone sulfate is the metabolite of Testosterone. Testosterone is the main male sex hormone which determination is useful for assessment of androgen status.
    Testosterone sulfate (pyridinium)
Cat. No. Product Name / Synonyms Application Reactivity