2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-Y0740
    4-Methoxybenzaldehyde
    		99.67%
    4-Methoxybenzaldehyde (p-anisaldehyde) is a fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .
    4-Methoxybenzaldehyde
  • HY-N0470
    L-Lysine hydrochloride
    		98.0%
    L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.
    L-Lysine hydrochloride
  • HY-Y0367
    Maleic Acid
    		99.86%
    Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes.
    Maleic Acid
  • HY-100921
    Spaglumic Acid
    		98.0%
    Spaglumic Acid (N-Acetylaspartylglutamic acid) is a neuropeptide found in millimolar concentrations in brain.
    Spaglumic Acid
  • HY-W015878
    5-Aminovaleric acid
    		≥98.0%
    5-Aminovaleric acid is believed to act as a methylene homologue of gamma-aminobutyric acid (GABA) and functions as a weak GABA agonist.
    5-Aminovaleric acid
  • HY-113201
    Tetradecanoylcarnitine
    		99.85%
    Tetradecanoylcarnitine is a human carnitine involved in β-oxidation of long-chain fatty acids.
    Tetradecanoylcarnitine
  • HY-N0390R
    L-Glutamine (Standard)
    L-Glutamine (Standard) is the analytical standard of L-Glutamine. This product is intended for research and analytical applications. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells.
    L-Glutamine (Standard)
  • HY-B0442
    Vardenafil
    		99.81%
    Vardenafil is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil can be used for the research of erectile dysfunction, hepatitis, diabetes[1]-[6].
    Vardenafil
  • HY-N0464
    D-(-)-Quinic acid
    		98.0%
    D-(-)-Quinic acid scavenges hydrogen peroxide (IC50=87.11 μg/mL) and exhibits antioxidant activity. D-(-)-Quinic acid is the inhibitor for MAO and α-Glucosidase (IC50 =93.75 μg/mL). D-(-)-Quinic acid is orally active.
    D-(-)-Quinic acid
  • HY-N0593S
    Deoxycholic acid-d4
    		98.0%
    Deoxycholic acid-d4 is the deuterium labeled Deoxycholic acid. Deoxycholic acid is specifically responsible for activating the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity.
    Deoxycholic acid-d<sub>4</sub>
  • HY-W016784
    Indole-3-acetamide
    		99.95%
    Indole-3-acetamide is a biosynthesis intermediate of 3-Indoleacetic acid (HY-18569). Indole-3-acetic acid is the most common natural plant growth hormone of the auxin class.
    Indole-3-acetamide
  • HY-W008150
    2-Hydroxy-3-methylbutanoic acid
    		98.57%
    2-Hydroxy-3-methylbutanoic acid is an α-hydroxy analogue of valine and a valine precursor that reduces urea excretion. 2-Hydroxy-3-methylbutanoic acid can promote the growth of chickens and rats, and is converted into valine in the body, participating in protein synthesis and maintaining nitrogen balance, thereby supporting animal growth and development. 2-Hydroxy-3-methylbutanoic acid has a more significant effect on the valine-deficient dietary model. 2-Hydroxy-3-methylbutanoic acid is mainly used in animal nutrition research to evaluate its potential application as a nitrogen source substitute in feed.
    2-Hydroxy-3-methylbutanoic acid
  • HY-P0241
    Neuromedin B
    		99.56%
    Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals.
    Neuromedin B
  • HY-N0339
    Syringic acid
    		99.85%
    Syringic acid is correlated with high antioxidant activity and inhibition of LDL oxidation.
    Syringic acid
  • HY-Y0546
    Benzophenone
    		99.99%
    Benzophenone is an endogenous metabolite. Benzophenone is a photosensitizer, that absorbs UV light, transfers its energy to DNA, and triggers DNA damage. Benzophenone can be used as the fragrance enhancer, ultraviolet curing agent, additive in plastics, or the flavor ingredient. Benzophenone can also be used in the manufacturing of insecticides, agricultural chemicals, hypnotics, antihistamines, and other pharmaceuticals. Benzophenone exhibits certain carcinogenicity in mouse/rat models under long term exposure. Benzophenone exhibits estrogenic activity.
    Benzophenone
  • HY-W015608
    2-Phenylpropionic acid
    		99.70%
    2-Phenylpropionic acid is an intermediate in the metabolism of alpha-Methylstyrene. 2-Phenylpropionic acid covalently binds to rat liver protein. 2-Phenylpropionic acid can be used in the research of nonsteroidal anti-inflammatory agents.
    2-Phenylpropionic acid
  • HY-50730
    Asparagusic acid
    Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor.
    Asparagusic acid
  • HY-P2807
    L-Lactate dehydrogenase, Microorganism
    L-Lactate dehydrogenase, Microorganism (LAD) is a redox enzyme. L-Lactate dehydrogenase catalyzes the reduction of pyruvate to L-lactate by NADH in vivo with absolute enantiospecificity.
    L-Lactate dehydrogenase, Microorganism
  • HY-W002112
    (±)-Nornicotine
    		98.84%
    (±)-Nornicotine is a major metabolite of Nicotine. (±)-Nornicotine is a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. (±)-Nornicotine disrupts β-catenin and ZO-1, and induces F-actin depolymerization. (±)-Nornicotine supports self-administration behavior. (±)-Nornicotine can be used in the research of atherosclerosis, Alzheimer's disease, and schizophrenia.
    (±)-Nornicotine
  • HY-126370A
    Geranylgeranyl pyrophosphate triammonium
    Geranylgeranyl pyrophosphate triammonium is a metabolite involved in protein geranylgeranylation. Geranylgeranyl pyrophosphate triammonium is the common precursor of  diterpenoids, for example, Paclitaxel. Geranylgeranyl pyrophosphate triammonium can be used for cancer research.
    Geranylgeranyl pyrophosphate triammonium
Cat. No. Product Name / Synonyms Application Reactivity