2. Metabolic Enzyme/Protease Neuronal Signaling GPCR/G Protein
  3. Endogenous Metabolite Adrenergic Receptor
  4. Phosphorylcholine chloride

Phosphorylcholine chloride  (Synonyms: Phosphocholine chloride)

Cat. No.: HY-B2233 Purity: ≥98.0%
SDS
COA
Handling Instructions Technical Support

Phosphorylcholine chloride (Phosphocholine chloride) is the main phospholipid component in eukaryotic biofilms. Phosphorylcholine chloride exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine chloride exhibits a surprising range of immunomodulatory properties.

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Phosphorylcholine chloride Chemical Structure

Phosphorylcholine chloride Chemical Structure

CAS No. : 107-73-3

Size Price Stock Quantity
Solid or liquid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in Water In-stock
Solid or liquid
500 mg In-stock
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5 g   Get quote  

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Customer Review

Based on 6 publication(s) in Google Scholar

Other Forms of Phosphorylcholine chloride:

Phosphorylcholine chloride Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Phosphorylcholine chloride (Phosphocholine chloride) is the main phospholipid component in eukaryotic biofilms. Phosphorylcholine chloride exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine chloride exhibits a surprising range of immunomodulatory properties[1].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

In Vitro

Phosphorylcholine chloride is a component of drug delivery micelles, which improves the efficiency of cellular internalization and increases the cytotoxicity of cytotoxins carried in micelles in HeLa cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Phosphorylcholine chloride Related Antibodies
In Vivo

Phosphorylcholine chloride (200-600 μmol/kg; ip; single dose) activates nicotinic and muscarinic cholinergic neurotransmission, stimulates the activation of α2-adrenergic receptors, and increases plasma glucagon and choline concentrations, thereby stimulating peripheral autonomic nervous system activity[3].
Phosphorylcholine chloride (2 μg; ip; once every two weeks for 4 months) induces the production of anti-PC and anti-oxLDL antibodies, increases mature B cells in the spleen, and reduces atherosclerotic lesions in the aortic root in mouse models[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

219.60

Formula

C5H15ClNO4P
CAS No.
Appearance

Solid-Liquid Mixture

Color

Colorless to light yellow

SMILES

O=P(OCC[N+](C)(C)C)(O)O.[Cl-]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1138.43 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5537 mL 22.7687 mL 45.5373 mL
5 mM 0.9107 mL 4.5537 mL 9.1075 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (455.37 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

SDS (393 KB)

COA (247 KB) HNMR (231 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.5537 mL 22.7687 mL 45.5373 mL 113.8433 mL
5 mM 0.9107 mL 4.5537 mL 9.1075 mL 22.7687 mL
10 mM 0.4554 mL 2.2769 mL 4.5537 mL 11.3843 mL
15 mM 0.3036 mL 1.5179 mL 3.0358 mL 7.5896 mL
20 mM 0.2277 mL 1.1384 mL 2.2769 mL 5.6922 mL
25 mM 0.1821 mL 0.9107 mL 1.8215 mL 4.5537 mL
30 mM 0.1518 mL 0.7590 mL 1.5179 mL 3.7948 mL
40 mM 0.1138 mL 0.5692 mL 1.1384 mL 2.8461 mL
50 mM 0.0911 mL 0.4554 mL 0.9107 mL 2.2769 mL
60 mM 0.0759 mL 0.3795 mL 0.7590 mL 1.8974 mL
80 mM 0.0569 mL 0.2846 mL 0.5692 mL 1.4230 mL
100 mM 0.0455 mL 0.2277 mL 0.4554 mL 1.1384 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Phosphorylcholine chloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Phosphorylcholine107-73-3PhosphocholineEndogenous MetaboliteAdrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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