1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-126752R
    Ophthalmic acid (Standard) 495-27-2
    Ophthalmic acid (Standard) is the analytical standard of Ophthalmic acid. This product is intended for research and analytical applications. Ophthalmic acid, an analogue of GSH, is a marker of oxidative stress and hepatic GSH consumption. Ophthalmic acid is an inhibitor of Glyoxalase I reaction.
    Ophthalmic acid (Standard)
  • HY-12752AR
    Alimemazine hemitartrate (Standard) 4330-99-8
    Alimemazine hemitartrate (Standard) is the analytical standard of Alimemazine hemitartrate. This product is intended for research and analytical applications. Alimemazine hemitartrate is a phenothiazine derivative that is generally used as an antipruritic agent and also a hemagglutinin (HA)-receptor antagonist.
    Alimemazine hemitartrate (Standard)
  • HY-12756AR
    E6446 dihydrochloride (Standard) 1345675-25-3
    E6446 (dihydrochloride) (Standard) is the analytical standard of E6446 (dihydrochloride). This product is intended for research and analytical applications. E6446 dihydrochloride is a potent and orally acitve TLR7 and TLR9 antagonist, used in the research of deleterious inflammatory responses. E6446 dihydrochloride is also a potent SCD1 inhibitor (KD: 4.61 μM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling. E6446 dihydrochloride also improves liver pathology in high-fat diet (HFD)-fed mice and may be useful in the study of non-alcoholic fatty liver disease (NAFLD).
    E6446 dihydrochloride (Standard)
  • HY-12767S2
    Carvedilol metabolite 4-Hydroxyphenyl Carvedilol-13C6 98%
    Carvedilol metabolite 4-Hydroxyphenyl Carvedilol-13C6 (4-Hydroxycarvedilol Carvedilol-13C6) is 13C labeled Carvedilol metabolite 4-Hydroxyphenyl Carvedilol.
    Carvedilol metabolite 4-Hydroxyphenyl Carvedilol-13C6
  • HY-12815AR
    MCC950 sodium (Standard) 256373-96-3
    MCC950 (sodium) (Standard) is the analytical standard of MCC950 (sodium). This product is intended for research and analytical applications. MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) is a potent, selective NLRP3 inhibitor with IC50s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively.
    MCC950 sodium (Standard)
  • HY-128448R
    Carmoisine (Standard) 3567-69-9 98%
    Carmoisine (Standard) is the analytical standard of Carmoisine. This product is intended for research and analytical applications. Carmoisine (Azorubine) is an azo dye that can be used as a food additive.
    Carmoisine (Standard)
  • HY-128799R
    CL097 (Standard) 1026249-18-2
    CL097 (Standard) is the analytical standard of CL097. This product is intended for research and analytical applications. CL097, a potent TLR7 and TLR8 agonist, induces pro-inflammatory cytokines in macrophages. CL097 induces NADPH oxidase priming, resulting in an increase of the fMLF-stimulated ROS production.
    CL097 (Standard)
  • HY-128922R
    Dexamethasone palmitate (Standard) 14899-36-6
    Dexamethasone palmitate (Standard) is the analytical standard of Dexamethasone palmitate. This product is intended for research and analytical applications. Dexamethasone palmitate (DXP) is a proagent of Dexamethasone (HY-14648). Dexamethasone palmitate can be used for the research of inflammation.
    Dexamethasone palmitate (Standard)
  • HY-129113R
    α-?Chaconine (Standard) 20562-03-2
    α-Chaconine (Standard) is the analytical standard of α-Chaconine. This product is intended for research and analytical applications. α-Chaconine inhibits the expressions of COX-2, IL-1β, IL-6, and TNF-α at the transcriptional level. α-Chaconine inhibits the LPS-induced expressions of iNOS and COX-2 at the protein and mRNA levels and their promoter activities in RAW 264.7 macrophages. Anti-inflammatory effects.
    α-?Chaconine (Standard)
  • HY-129440R
    N-(p-Coumaroyl) Serotonin (Standard) 68573-24-0 98%
    N-(p-Coumaroyl) Serotonin (Standard) is the analytical standard of N-(p-Coumaroyl) Serotonin. This product is intended for research and analytical applications. N-(p-Coumaroyl) Serotonin is a polyphenol isolated from the seeds of safflower and has antioxidative, anti-atherogenic and anti-inflammatory properties. N-(p-Coumaroyl) Serotonin inhibits PDGF-induced on phosphorylation of PDGF receptor and Ca2+ release from sarcoplasmic reticulum. N-(p-Coumaroyl) Serotonin ameliorates atherosclerosis and distensibility of the aortic wall in vivo and is usually used for the atherosclerosis research.
    N-(p-Coumaroyl) Serotonin (Standard)
  • HY-129524R
    Ethylene dimethanesulfonate (Standard) 4672-49-5
    Ethylene dimethanesulfonate (Standard) is the analytical standard of Ethylene dimethanesulfonate. This product is intended for research and analytical applications. Ethylene dimethane sulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs.
    Ethylene dimethanesulfonate (Standard)
  • HY-130046R
    16-Epiestriol (Standard) 547-81-9
    16-Epiestriol (Standard) is the analytical standard of 16-Epiestriol. This product is intended for research and analytical applications. 16-Epiestriol is a metabolite of the endogenous estrogen estrone with antibacterial and anti-inflammatory effects.
    16-Epiestriol (Standard)
  • HY-130313R
    Sodium lauroyl glutamate (Standard) 29923-31-7
    Sodium lauroyl glutamate (Standard) is the analytical standard of Sodium lauroyl glutamate. This product is intended for research and analytical applications. Sodium lauroyl glutamate is an anionic amino acid surfactant. Sodium lauroyl glutamate has the irritant contact dermatitis potential, and possible anti-irritating potential in a surfactant mixture on human skin.
    Sodium lauroyl glutamate (Standard)
  • HY-13038AR
    Fostamatinib (Standard) 901119-35-5
    Fostamatinib (Standard) is the analytical standard of Fostamatinib. This product is intended for research and analytical applications. Fostamatinib (R788) is the oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).
    Fostamatinib (Standard)
  • HY-13038BR
    Fostamatinib disodium hexahydrate (Standard) 914295-16-2
    Fostamatinib (disodium hexahydrate) (Standard) is the analytical standard of Fostamatinib (disodium hexahydrate). This product is intended for research and analytical applications. Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).
    Fostamatinib disodium hexahydrate (Standard)
  • HY-131002A
    DPTIP hydrochloride 2361799-64-4 98%
    DPTIP hydrochloride is a potent brain penetrant neutral sphingomyelinase 2 (N-SMase 2) inhibitor (exosome inhibitor), with an IC50 of 30 nM.
    DPTIP hydrochloride
  • HY-131106S
    Clorprenaline-d7 2748354-86-9 98%
    Clorprenaline-d7 is a deuterium labeled Clorprenaline. Clorprenaline is a β2-adrenergic receptor agonist that is implicated in bronchial expansion. Clorprenaline has the potential for asthma research.
    Clorprenaline-d7
  • HY-131118R
    Desmethyl Ketoprofen (Standard) 22071-22-3
    Desmethyl Ketoprofen (Standard) is the analytical standard of Desmethyl Ketoprofen. This product is intended for research and analytical applications.
    Desmethyl Ketoprofen (Standard)
  • HY-131145R
    Brombuterol hydrochloride (Standard) 21912-49-2
    Brombuterol (hydrochloride) (Standard) is the analytical standard of Brombuterol (hydrochloride). This product is intended for research and analytical applications. Brombuterol hydrochloride (Bromobuterol hydrochloride) is a β-adrenergic receptor agonist.
    Brombuterol hydrochloride (Standard)
  • HY-131150R
    Ristomycin sulfate (Standard) 11140-99-1
    Norfenefrine (hydrochloride) (Standard) is the analytical standard of Norfenefrine (hydrochloride). This product is intended for research and analytical applications. Norfenefrine hydrochloride is an orally active, endogenously found α-adrenergic agonist and can be used for the research of female stress incontinence.
    Ristomycin sulfate (Standard)
Cat. No. Product Name / Synonyms Application Reactivity